JP2016207013A - Specimen storage tool, culture container, automatic management device, and identity guarantee system in cell medical/specimen inspection using the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To prevent the cultured cells or tissues of other than a donor from being used with mistake so that traceability having reliability is secured when the securing of the identify between cells and tissues collected from the inside of the body of a subject and the cells and the tissues actually inspected and the returning of the tissues collected and subjected to culture treatment by cell medical to a donor are executed.SOLUTION: An identity securing system of this specimen and removed tissues includes: a step of collecting living tissues 6 from a specimen 5 using a biopsy needle 1 having IC tag IC tag 4 written with identification information of the specimen 5; and a transfer step of storing the living tissues 6 collected by the biopsy needle 1 into an inspection/culture container culture container 7 having an attached container IC tag IC tag 8 and transferring information of an IC tag IC tag 4 of the biopsy needle 1 to the attached container IC tag IC tag 8. The collation of an inspection result of the living tissues 6 with the specimen 5 is performed by information of the attached container IC tag IC tag 8.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a system for ensuring the identity between a specimen and an excised tissue in cell medicine or specimen examination, and in particular, collects cells and tissues from a specimen such as a human body or its excised tissue or organ from a living body, and performs processing such as examination and culture. In order to prevent mistakes and confusion when replacing the specimen and the original human body after performing these treatments, cells that guarantee the identity of the specimen and the extracted tissue with the test results and the individual. The present invention relates to an identity guarantee system system in medical care and specimen testing.

  In recent years, tissues such as blood and tissues collected from human bodies and subcutaneous fat and skin of cells are collected, and the tissues and cells are processed and recovered, and the cells are processed using other cell biological techniques. The development of cell therapy such as regenerative medicine is remarkable. For example, in this type of medical treatment for repairing and regenerating tissues and organs lost due to some kind of disorder, it is important to prevent mistakes when the collected tissues are cultured and then returned to the living body. Until now, some classic methods have been used to prevent mistakes. For example, as an example, one incubator for culturing tissue is prepared for one patient and tissue or cells are cultured in the incubator, or one room for culturing is prepared for one patient. A method of culturing tissues and cells. This kind of classic mistake prevention measure is not a perfect tissue mistake prevention measure because there is a possibility that a mistake occurs during culture because human intervention is involved. In addition, there is a problem that it is necessary to prepare an apparatus and a room for each patient, which is expensive. In specimen testing, it is also important to prevent specimens and test results from being mistaken. Samples such as cells, blood, subcutaneous fat, and skin tissue collected from living organisms are examined, and the test results are notified to the patient. In the case where treatment is performed based on the test result, conventionally, the above-described measures for preventing sample contamination have been taken.

  As conventional technologies, research and development of cell and tissue management systems, cell and tissue inspection and culture systems, and automated cell management systems are underway, and they are also used for collecting biological tissues from the human body. Improvements and developments have been made on biopsy needles. For example, the information processing system disclosed in Patent Document 1 discloses a system that collects and accumulates parameters that are sources of quality control for cell management of a cell culture plant, and uses them effectively for actual quality control. Yes. Further, in the cell management system and the cell management method of Patent Document 2, an IC tag having a wireless communication function and an information storage function is attached to a container that accommodates cells, and identification information corresponding to the cells accommodated in the container is wirelessly communicated. Thus, the history of each process of cells is registered and managed in a database so as to prevent the danger given to the living body in actual regenerative medicine. Furthermore, a biopsy needle has been disclosed in which the structure of the needle tip is devised so that the target tissue can be separated from other tissues when the tissue is punctured and collected from a living body to ensure tissue collection (Patent Document 3). 4).

JP 2006-4299 A JP 2005-332046 A JP 2006-320546 A JP 2008-183020 A

  By repairing and regenerating lost tissues and organs by culturing and processing cells or tissues of the subject's own or other people, such as cells, and using them in place of damaged or lost organs In regenerative medicine, it is required to ensure traceability in the process of culturing collected cells and tissues, and when returning cultured cells, tissues, or organs to the original human body, There should be no mistakes that make mistakes. In particular, when dividing or replicating cultured tissues into multiple pieces, it is necessary to check whether other cultured tissues are mixed in the process of culturing into multiple divided tissues. Is required to be done easily and quickly. Furthermore, in the area of specimen testing, it is necessary to construct a reliable management system so that there are no mistakes in the various processing processes of the collected tissue.

  In the present invention, when cells or tissues collected from the body of a subject and cells actually examined, ensuring the identity between the tissues, and performing treatment for returning the tissues collected and cultured in regenerative medicine to the person In addition, we provide a system for ensuring the identity of specimens and extracted tissues, specimens, and test results in cell medicine and specimen testing, which can prevent mistakes during the procedure and ensure reliable traceability. For the purpose.

  According to the identity assurance system in the cell medicine / specimen test of the present invention, a specimen container having an IC tag, a culture container having an IC tag, and information written to the IC tag An automatic management device equipped with a reader / writer for reading, the automatic management device reads biometric information stored in an IC tag of the specimen container, and the same biometric information is stored in the culture container There is provided an identity guarantee system in cell medicine or specimen testing, characterized by having means for writing to the IC tag.

  According to another aspect of the present invention, there is provided a culture vessel in which an IC tag is disposed, and an automatic management device equipped with a reader / writer for writing / reading information to / from the IC tag. The device has a means for reading biometric information stored in an IC tag of a specific culture container and writing the same biometric information in an IC tag of another culture container An identity guarantee system is provided.

  The automatic management device reads the biometric information stored in the IC tag of the specific specimen container and / or the IC tag of the culture container, and replicates the biometric information to the IC tags of other culture containers And writing means.

  The automatic management device reads the biometric information stored in the IC tag of the specimen container and / or the IC tag of the culture container arranged in the first generation communication area, and is arranged in the second generation communication area. And a means for copying and writing to the IC tag of the culture container.

  The automatic management apparatus reads the biometric information stored in the IC tag of the specimen container and / or the IC tag of the culture container arranged in the first generation communication area, and stores the information in a plurality of second generation communication areas. It has a means to duplicate and write to the IC tag of the culture container arranged.

  It has a means for judging the identity of the biometric information written in the IC tag of the specimen container and the biometric information written in the IC tag of the culture container.

  The biometric identification information is partial information of gene sequence information that can identify a solid in the gene sequence information.

  History information is written in the IC tag.

  The sample container is at least one of a syringe, a biopsy needle, and a collected container for storing collected cells / tissues, and an IC tag is attached to the sample container of the sample container.

  The culture container is a container for accommodating and culturing cells / tissues, and is characterized in that an IC tag is disposed in a specimen storage part of the culture container.

  According to another aspect of the present invention, the automatic management apparatus is equipped with a reader / writer, and an IC tag disposed in a sample container and / or culture container installed in the first generation communication area. A reader for an identity assurance system in cell medicine, comprising means for reading and storing information stored in an IC tag disposed in a culture container installed in a second generation communication area A writer is provided.

  The automatic management apparatus has one first-generation communication area and a plurality of second-generation communication areas.

  The automatic management apparatus is equipped with anti-collision means.

  The automatic management apparatus has a mounting table on which the specimen container and / or the culture container are mounted, and the reader / writer is built in the mounting table.

  According to another aspect of the present invention, an IC tag is disposed in a sample container of a sample container that includes a sample collection unit for collecting cells / tissues.

  An IC tag is detachably disposed in the sample collection unit, and has a structure that allows the IC tag to remain in a collection source organ.

  According to another aspect of the present invention, an IC tag is disposed in a sample container of a culture container that includes a sample container for culturing cells / tissues.

  According to another aspect of the present invention, there is provided an IC tag and / or a specimen container for culturing cells / tissues disposed in a specimen container of a specimen container having a specimen collection part for collecting cells / tissues. An anti-collision means is mounted on the IC tag disposed in the specimen container of the culture container provided.

  According to the present invention, it is possible to perform reliable traceability by collecting a test target, performing a process such as culture, and collating the result information with an individual who has collected the result in general cell medicine and specimen testing.

  In the field of cell medicine in which cells and tissues after culture and treatment are returned to the original human body (specimen) to regenerate the tissues and organs, a biopsy needle having two IC tags written with the same information is used. Used when collecting one or more of the biopsy needles at the time of collection of tissue or the like, and by embedding the information of the other IC tag into the IC tag on the container side, The IC tag information embedded in the collection site and the cells to be returned to the body can be returned while matching the biometric information with the IC tag information of the container containing the tissue, so that mistakes such as mistakes can be prevented. .

It is the figure which showed according to the operation process the identity guarantee system of the sample and extracted tissue which concern on the Example of this invention. It is the figure which showed the mode of the information transfer in the automatic management apparatus in the case of dividing | segmenting the extract | collected cell and structure | tissue into a plurality and performing treatments, such as an inspection and culture, respectively. It is the figure which showed the identity guarantee system of the sample and extracted tissue which concern on the other Example of this invention according to the operation process.

  Next, the present invention will be described based on examples with reference to the drawings. The identity guarantee system in the cell medicine and the specimen test of the present invention will be described. Examples of the specimen include the human body of the subject or cells taken from the human body, and tissues such as blood, subcutaneous fat, and skin. Of course, the present invention can be applied to other animals such as a mouse, but here, a human who works most effectively with the prevention measures will be described as an example.

  First, the instrument and apparatus used in the system of the present invention will be described. First, the specimen container will be described with reference to FIG. Specimen container contains syringes that collect blood, specimen collection devices such as biopsy needles that collect tissues, or cells, blood, organs, and other tissues that are removed from living bodies by syringes, biopsy needles, surgical operations, etc. It is a storage device such as a test tube, petri dish (petri dish), or pus basin. In other words, the sample container means a container for storing a sample to be taken out from the body in the first stage. In this embodiment, a biopsy needle 1 having a cylinder 1a as an instrument for collecting cells and tissues and a plunger 1b sliding in and out of the cylinder 1a is used as a specimen container. A concave groove 2 is formed in the vicinity of the tip of the plunger 1b to facilitate collection of cells and tissues, and an IC tag 4 capable of wireless communication is attached to the knob 3 at the rear end of the plunger 1b. ing. The tip of the plunger 1b is a sharp tip so that the sample can be easily punctured. Note that the specimen container is not limited to the above-described tool. The cell and tissue collection device is not limited to the biopsy needle having the above structure, and may be a collection device having another structure.

  An IC tag is disposed on the sample container. Referring to FIG. 1, in the biopsy needle 1, an IC tag 4 capable of writing information is attached to the rear end portion of the plunger 1b that can be inserted into and removed from the cylinder 1a. In addition, the attachment location of an IC tag is not restricted to this. When the specimen container is a syringe, an IC tag is attached to the container when the cylinder, petri dish, test tube, pus basin, or the like. This IC tag is a chip-type RFID tag equipped with a so-called non-volatile memory, and a large amount of various information can be written by wireless communication by a reader / writer described later.

  As a variation of the sample container, as shown in FIG. 3, an IC tag or a biopsy needle 20 having a structure in which an IC tag is detachably disposed in the sample collection unit and the IC tag remains in the organ from which the sample is collected. There is a specimen container such as. In this case, the biopsy needle 20 is provided with a detachable IC tag 21 in the vicinity of the distal end of the plunger 20b that can be inserted into and removed from the cylinder 20a, and the IC tag 4 shown in FIG. Is attached.

  Next, the culture container will be described. The culture container is a container for culturing cells taken out from the body and tissues such as blood and organs. In the embodiment, the culture container is a petri dish, and the IC tag 8 attached to the container is attached to the container. The type of culture vessel is not limited to this, and examples include test tubes and other vessels that can contain cells and tissues. Similarly to the IC tag 4, the container attached IC tag 8 is a chip-type RFID tag equipped with a so-called nonvolatile memory, and a large amount of various information can be written by wireless communication by a reader / writer described later. Yes.

  Next, the automatic management apparatus 10 will be described. The automatic management device 10 is a device equipped with a reader / writer that can write / read information to / from an IC tag by wireless communication, and is an auxiliary storage device that can read / write information to / from the IC tag by wireless data communication. is there. In the embodiment, as shown in FIG. 1, the automatic management apparatus 10 includes a mounting table on which a specimen container and a culture container are mounted, and a reader / writer built in the mounting table. 10 is connected to a computing device (not shown) such as a computer as necessary. The automatic management apparatus 10 is mounted on the same mounting table as the means for copying the information read from the IC tags 4 and 8 attached to the specimen container or the culture container mounted on the mounting table. Means for writing the replicated information on the IC tag 8 of the culture vessel is provided. In this case, it is desirable to mount an anti-collision function on the IC tag. In addition, information input directly to the automatic management apparatus 10 through an arithmetic device (not shown) such as a computer connected to the automatic management apparatus 10 or directly to the automatic management apparatus 10 can be written in the IC tag.

  As a variation of the automatic management apparatus 10, as shown in FIG. 2, there is an automatic management apparatus 101 having a plurality of communication areas on the mounting table. In the embodiment of FIG. 2, the mounting table of the automatic management apparatus 101 is divided into three communication areas, and the IC tags 4 and 8 attached to the specimen container or the culture container mounted in the first generation communication area. Means for reading the information from the first generation area, means for copying the information read in the first generation communication area, and means for writing the copied information in the IC tag 8 of the second generation communication area 15 of the two areas. Note that the number of communication areas is not limited to this. In the communication area, in addition to the culture container and the specimen container, other instruments with IC tags attached may be placed to read / write information. In addition, information input directly to the automatic management apparatus 101 can be newly written in the IC tag through an arithmetic unit (not shown) such as a computer connected to the automatic management apparatus 101 as necessary. In the automatic management apparatus 101 having a plurality of communication areas, it is desirable that the reader / writer has an anti-collision function.

  In addition, the identity determination means of the biometric information arbitrarily added to the system of the present invention is provided in an arithmetic device (not shown) connected to the automatic management devices 10 and 101, and the automatic management devices 10 and 101 perform IC. A match / mismatch of the biometric information read from the tag is determined. When the biometric information is gene sequence information, it is determined whether or not the degree of coincidence of the characteristic gene sequence information part that identifies the individual is equal to or higher than a threshold that can be determined to be the same solid. .

  As a first embodiment of this system, a flow when the present invention is used for cell medicine will be described. In the field of cytomedicine, cells and tissues taken out from the human body are cultured and differentiated to create desired tissues and organs, which are then returned to the body of the person. At this time, it is very important that the person from whom the cells and tissues are collected and the person who returns the created tissues and organs are the same solid. Therefore, it is necessary to take measures to prevent the culture object from being mistaken.

  In the IC tag 4 of the specimen container 1, biometric information for identifying a human solid is written at an initial stage. The simplest biometric identification information is a combination of numbers and numbers such as medical chart numbers, but the biometric identification information with high accuracy is the gene sequence information from the viewpoint of prevention of patient confusion. A part of the characteristic gene sequence information that can identify the is used. In addition, when gene sequence information is used as biometric identification information, gene sequence information may be written in an IC tag in advance, or gene sequence information analyzed from the sample 5 at the stage of collecting the sample 5 is automatically managed. 10 and 101 can be said to be the writing of the biometric information with the highest accuracy.

  Next, a case where information is replicated from the specimen container to the culture container using the automatic management apparatus 10 will be described. In the IC tag 4 of the biopsy needle 1 as a specimen container, biometric identification information for identifying a human solid is written at an initial stage or a stage set in the automatic management apparatus 10 first. First, as shown in FIG. 1 (a), the sampler operates the rear end knob portion 3 of the biopsy needle 1 to project the distal end portion of the plunger 1b from the cylinder 1a, and the cells and tissues of the specimen 5 (or living body). The sampled portion of the sample is punctured, and a sample of the sample collected as shown in FIG. 1B or a part of the sample 5 (or living body) of the tissue 6 is collected as the culture object 6 and stored in the storage unit. . Here, information for specifying the target specimen 5 is written in the IC tag 4 of the biopsy needle 1 in advance. And as shown in FIG.1 (c), the to-be-cultured object 6 extract | collected with the biopsy needle 1 is accommodated in the container 7 for culture | cultivation. Further, as shown in FIG. 1 (d), an operation for operating the apparatus such as turning on the automatic management apparatus 10 by setting the culture vessel 7 containing the culture object 6 and the biopsy needle 1 in the automatic management apparatus 10 is performed. Then, the automatic management apparatus 10 reads the biometric information recorded on the IC tag 4 of the biopsy needle 1 and copies and writes it on the container-attached IC tag 8 of the culture container 7. In addition, the automatic management apparatus 10 can arbitrarily input information indicating a collection site, information indicating a collection date and time, information indicating a processing purpose such as examination and culture, and history information such as patient chart information, which is input through an arithmetic device (not shown). Write as information. In some cases, the electronic signature information of the person or organization involved in the procedure such as collection is also written. For example, a person who has actually collected tissue inputs his / her identification information to the IC tag 4 of the biopsy needle 1 used at the time of collection. Instead of writing biometric information in advance on the IC tag 4 of the biopsy needle 1, it may be written for the first time when the biopsy needle 1 is installed in the automatic management apparatus 10. In addition, the precision of prevention of the interposition of the to-be-cultured material 6 further increases by performing the operation | work which accommodates the to-be-cultured material 6 in the container 7 for culture | cultivation with the mounting base of the automatic management apparatus 10. FIG.

  In this way, the culture container 7 is such that the specimen container such as the biopsy needle 1 holds biometric information relating to the specimen 5 to be punctured and collected, and the cells after the culture treatment in the culture container 7 It is assured that the culture object 6 such as or tissue is collected from this specific specimen 5 (or living body).

Next, in the case where the culture object 6 is moved from the specimen container to the culture container or from the culture container to the next-generation culture container using the automatic management apparatus 101 of the development system of the automatic management apparatus 10 Will be described. In regenerative medicine, an object to be cultured 6 such as cells and tissues housed in a culture container 7 from a specimen collection tool is divided into a plurality of parts and transferred to a plurality of containers 7, or cells or tissues are cultured. Differentiating over several generations, it is transferred to the culture vessel 7 each time. Even in such a case, the automatic management apparatus 10 or the automatic management apparatus 101 according to the present invention is effectively used. As shown in FIG. 2, the mounting table container mounting table of the automatic management apparatus 101 includes a first generation source communication area 12 on which the original culture container 7 is mounted, and next to divided tissue, cultured tissue, and the like. It has a plurality of second-generation destination communication areas 15 on which next-generation culture containers 13 and 14 for accommodating the generations to be cultured 11 are placed. As shown in FIG. 2, the culture container 7 containing the culture object 6 is set in the first generation communication area 12 of the automatic management apparatus 101, and the next generation culture container 13, in the second generation communication area 15. 14 is set, the automatic management apparatus 101 reads the biometric information recorded on the IC tag 4 of the culture vessel 7 and replicates it by a duplicating means. Then, the copied biological identification information is written in the IC tags 17 and 18 of the next-generation culture containers 13 and 14. Further, the automatic management apparatus 101 writes history information such as information indicating a culture process input through an arithmetic device (not shown).

  The outline of the operation of the automatic management apparatus 101 having a plurality of movement destination areas 15 will be described. First, the movement source container 7 containing the tissue 6 with the automatic management apparatus 10 in an activated state is moved to the movement source area 12 of the apparatus 10. When the tissue 6 in the container is divided and transferred to the containers 13 and 14 in the movement destination region 15 by hand, the IC tag 8 of the movement source culture container 7 is in the meantime. The information read from the information is copied by the copying means and written to the IC tags 17 and 18 of the containers 13 and 14 via the communication means inside the apparatus. All the first-generation, second-generation to n-th generation tissue cultures 11 divided or cultured and differentiated thereby have the same biological identification information as the original first-generation culture object 6 and thus the specimen 5. It becomes possible to manage. The automatic management apparatus 101 is also provided with electronic signature information means for specifying a person who operates. As a result, it is possible to prevent the automatic management apparatus from operating unless the operating person inputs his / her identification information, thereby preventing unauthorized operation by an unauthorized person. Therefore, the living body specific information of the living body (the living body to which the tissue or organ as the culture object is returned) to be treated by regenerative medicine and the living body of the last cultured object (the tissue or organ to be returned to the living body) used for cell medicine By determining the coincidence with the specific information by the determining means, the identity between the living body and the tissue or organ is ensured. Since history information such as the culture process of the culture to be cultured recorded on the IC tag can be traced, traceability of the culture is also ensured. It should be noted that the specimen (or living body) and the subject can be more accurately obtained if the culture treatment or the transfer of the subject to be cultured from the culture vessel 7 to the next-generation culture vessel 13 or 14 is performed on the mounting table of the automatic management apparatus 10 or 101. The identity of the culture is ensured.

  Next, as a second embodiment of the present system, a flow when the system of the present invention is used for inspection will be described as an example with reference to FIG. In the medical examination field, a part of a specimen such as a cell or tissue taken out of a human body is divided or cultured, and analysis of cells, blood, tissue, or gene is performed, and a test result is notified or the test is performed. Treatment is based on the results. Therefore, it is very important that the solid provided with the specimen and the test result are the same solid. Therefore, it is necessary to take measures to prevent the inspection object from being mixed.

  The case where the system of the present invention is used for the inspection is basically the same as the case of the cell medicine of the first embodiment. Therefore, in the second embodiment, a case where an IC tag is also left on the specimen 5 side, which is characteristic in the case of examination, will be described. Biological identification information for identifying the specimen in the initial stage is written in both the IC tags 4 and 21 of the biopsy needle 20. The simplest biometric identification information is a combination of numbers and numbers such as medical chart numbers, but the biometric identification information with high accuracy is gene sequence information from the viewpoint of prevention of patient confusion. It is desirable to write a part of characteristic gene sequence information that can be specified as biometric identification information. In addition, when gene sequence information is used as biometric information, the gene sequence information may be written in an IC tag in advance, or the gene sequence information analyzed from this sample at the stage of collecting cells or tissues can be read by a reader / writer. Writing to the IC tag 4 can be said to be the writing of biometric information with the highest accuracy.

  Next, a case where information is replicated from the specimen container to the culture container using the automatic management apparatus 10 will be described. In the IC tags 4 and 21 of the biopsy needle 20 as a specimen container, biometric information for identifying a human solid is written at an initial stage. As shown in FIG. 3A, the sampler operates the rear end knob 3 of the biopsy needle 20 to project the tip of the plunger 20b from the cylinder 20a, and collects the cells and tissues of the specimen 5 (or living body). The part is punctured, and a part of the specimen 5 (or living body) collected as shown in FIG. At this time, the IC tag 21 provided at the needle tip is detached from the biopsy needle 20 and remains on the sample 5 side. In addition, as shown in FIG. 3C, the test object 6 collected by the biopsy needle 20 is accommodated in the culture container 7. Furthermore, as shown in FIG. 3 (d), when the container 7 and the biopsy needle 20 containing the object 6 to be inspected are set in the automatic management apparatus 10, and an operation for operating the apparatus such as turning on the automatic management apparatus 10 is performed, The automatic management apparatus 10 reads the biometric information recorded on the IC tag 4 of the biopsy needle 20 and copies and writes it on the IC tag 8 of the culture container 7. In addition, the automatic management apparatus 10 can include arbitrary information such as information indicating a collection site input through an arithmetic unit (not shown), information indicating a collection date and time, information indicating a processing purpose such as an examination, and medical record information of a patient. Write as. Written. In some cases, the electronic signature information of the person or organization involved in the procedure such as collection is also written. In addition, the system for preventing the inspected object 6 from being mixed is further enhanced by performing the operation of storing the inspected object 6 in the culture vessel 7 on the mounting table of the automatic management apparatus 10. Instead of writing biometric information in advance on the IC tag 4 of the biopsy needle 1, it may be written for the first time when the biopsy needle 1 is installed in the automatic management apparatus 10.

  Next, the case where the test object 6 is moved from the specimen container to the culture container or from the culture container to the next-generation culture container using the automatic management apparatus 101 will be described. In the medical examination, an object to be inspected 6 such as a cell or a tissue accommodated in the culture container 7 is divided for inspection and transferred to several culture containers. Even in such a case, the automatic management apparatus 10 or the automatic management apparatus 101 according to the present invention is effectively used. As shown in FIG. 2, the mounting table of the automatic management apparatus 101 accommodates a first generation communication area 12 on which the original culture container 7 is mounted, and an inspected object 11 such as a divided tissue or a cultured tissue. And a plurality of second-generation communication areas 15 on which the next-generation culture vessels 13 and 14 are placed. As shown in FIG. 2, an operation for operating the apparatus such as turning on the automatic management apparatus 101 by setting the culture container 7 containing the test object 6 and the next-generation culture containers 13 and 14 in the automatic management apparatus 101. Then, the automatic management apparatus 101 reads the biometric information recorded on the IC tag 4 of the culture container, duplicates it, and duplicates it on the IC tags 17 and 18 of the next-generation culture containers 13 and 14. Write. Further, the automatic management apparatus 101 writes history information indicating an inspection process input through an arithmetic unit (not shown) as arbitrary information.

  When the test result is finally clarified, the determination means determines the identity between the IC tag 8 of the culture container 7 in which the final test object 6 is accommodated and the IC tag 21 left on the specimen 5 side. This ensures the identity of the specimen and the experimental result. Since the history information such as the inspection process of the inspection object recorded on the IC tag can be traced, the traceability of the inspection object is also ensured. It should be noted that the specimen (or living body) and the subject can be more accurately obtained if the culture treatment or the transfer of the subject to be cultured from the culture vessel 7 to the next-generation culture vessel 13 or 14 is performed on the mounting table of the automatic management apparatus 10 or 101. The identity of the culture is ensured.

  As described above, according to the present invention, a subject to be examined such as a part of an organ is collected in the entire cell medical region or specimen examination region (including placing it on the IC tag examination target side as necessary) It is possible to perform reliable traceability using a flow of processing such as culturing (simultaneously copying biological identification information) and collating it with the individual from whom the information is collected. Therefore, it is possible to provide highly safe and accurate medical care and testing by performing cell medicine and specimen testing using the system of the present invention.

DESCRIPTION OF SYMBOLS 1,20 Biopsy needle 1a 20a Cylinder 1b 20b Plunger 2 Groove 3 Knob part 4, 8, 21 IC tag 5 Specimen 6 Culture object / inspection collection tissue 7 Culture container 8 Container-attached IC tag 10 Automatic management device 101 Automatic management device 11 Culture object / inspection divided tissue 12 First generation communication area (movement source area)
13, 14 Cultivation container destination container 15 Second generation communication area (destination area)
16 Container placement surfaces 17 and 18 IC tag 19 on the destination container 19

Claims (18)

  A specimen container having an IC tag, a culture container having an IC tag, and an automatic management device equipped with a reader / writer for writing / reading information to / from the IC tag, The automatic management apparatus has means for reading biological identification information stored in an IC tag of the specimen container and writing the same biological identification information in the IC tag of the culture container. Identity guarantee system in inspection.   A culture vessel comprising an IC tag; and an automatic management device equipped with a reader / writer for writing / reading information to / from the IC tag, wherein the automatic management device is an IC tag for a specific culture vessel An identity assurance system in cell medicine / specimen testing, comprising means for reading the biometric information stored in and storing the same biometric information in an IC tag of another culture vessel.   The automatic management device reads the biometric information stored in the IC tag of the specific specimen container and / or the IC tag of the culture container, and replicates the biometric information to the IC tags of other culture containers The identity assurance system in the cell medicine / specimen test according to claim 1, further comprising a writing unit.   The automatic management apparatus reads the biometric information stored in the IC tag of the specimen container and / or the IC tag of the culture container arranged in the first generation communication area, and is arranged in the second generation communication area. 4. The identity assurance system for cell medicine / specimen testing according to claim 1, further comprising means for copying and writing to an IC tag of the culture container.   The automatic management device reads the biometric information stored in the IC tag of the specimen container and / or the IC tag of the culture container arranged in the first generation communication area, and stores the information in a plurality of second generation communication areas. 5. The identity assurance system in cell medicine / specimen testing according to any one of claims 1 to 4, further comprising means for copying and writing to an IC tag of a culture container arranged.   6. The apparatus according to claim 1, further comprising means for determining the identity of the biometric information written in the IC tag of the specimen container and the biometric information written in the IC tag of the culture container. The identity guarantee system in the cell medicine / specimen test described in 1.   7. The identity assurance system for cell medicine / specimen testing according to any one of claims 1 to 6, wherein the biological identification information is partial information of gene arrangement information that can identify a solid in the gene arrangement information.   The history information is written in the IC tag, the identity guarantee system in the cell medicine / specimen test according to any one of claims 1 to 7.   2. The sample container is at least one of a syringe, a biopsy needle, and a collected container for storing collected cells / tissues, and an IC tag is disposed in a sample container of the sample container. The identity guarantee system in the cell medical treatment / specimen inspection according to any one of 1 to 8.   The cell medicine according to any one of claims 1 to 8, wherein the culture container is a container for containing and culturing cells / tissues, and an IC tag is disposed in a specimen container of the culture container.・ Identity assurance system for specimen testing.   The automatic management device is equipped with a reader / writer, reads information stored in an IC tag disposed in a specimen container and / or culture vessel installed in the first generation communication area, An automatic management device for an identity assurance system in cell medicine, comprising means for copying and writing to an IC tag disposed in a culture container installed in a communication area of a generation.   12. The automatic management apparatus for an identity assurance system in cell medical / specimen testing according to claim 11, wherein the automatic management apparatus has one first-generation communication area and a plurality of second-generation communication areas.   13. The automatic management apparatus for an identity assurance system in cell medicine / specimen testing according to claim 11 or 12, wherein the automatic management apparatus is equipped with anti-collision means.   The automatic management apparatus has a mounting table for mounting a specimen container and / or a culture container, and the reader / writer is built in the mounting table. Automatic management device for identity assurance system in cell therapy and specimen testing.   A sample container for an identity assurance system in a cell medical / specimen test, wherein an IC tag is disposed in a sample container of a sample container having a sample collection unit for collecting cells / tissues.   16. The identity assurance system for cell medical / specimen testing according to claim 15, wherein the IC collecting unit is detachably disposed in the sample collecting unit, and has a structure in which the IC tag remains in the organ from which the IC tag is collected. Sample container.   A culture container for identity assurance system in cell medicine / specimen inspection, wherein an IC tag is disposed in a specimen storage part of a culture container provided with a specimen storage part for culturing cells / tissues.   Specimen container of culture container having IC tag and / or sample container for culturing cells / tissue arranged in sample container of sample container having sample collecting part for collecting cell / tissue An IC tag for an identity assurance system in cell medicine / specimen testing, characterized in that an anti-collision means is mounted on the IC tag disposed in the box.