JP2013003040A - Moisture transpiration amount measuring patch - Google Patents

Moisture transpiration amount measuring patch Download PDF

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JP2013003040A
JP2013003040A JP2011136208A JP2011136208A JP2013003040A JP 2013003040 A JP2013003040 A JP 2013003040A JP 2011136208 A JP2011136208 A JP 2011136208A JP 2011136208 A JP2011136208 A JP 2011136208A JP 2013003040 A JP2013003040 A JP 2013003040A
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color
moisture
color former
transparent film
moisture transpiration
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JP5709049B2 (en
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Shusuke Yokoi
秀輔 横井
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Life Care Giken Inc
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Life Care Giken Inc
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Abstract

PROBLEM TO BE SOLVED: To provide a moisture transpiration amount measuring patch with a simple structure capable of quantitatively measuring a moisture transpiration amount accurately by a simple operation of attaching it on a surface to be measured such as human skin.SOLUTION: A moisture transpiration amount measuring patch comprises: a transparent film 12 which is attached to the surface to be measured such as human skin by an adhesive 22; a coloring agent storage part 26 which faces the surface of the transparent film 12 in the side of the adhesive 22 and contains a coloring agent 28 absorbed in it; and a color changing part 24 which is connected to the coloring agent storage part 26 and is formed in a long shape in one direction, allowing the coloring agent 28 to permeate in the longitudinal direction. It is provided with: a moisture impermeable layer 30 which covers the surface of the color changing part 24 at the opposite side from the side of the transparent film 12; and a moisture permeable layer 34 which is arranged on the adhesive 22 side of the transparent film 12 and covers the coloring agent storage part 26. The transparent film 12 is provided with: a transparent display part 16 which makes the color changing part 24 visible; and a print part 14 which is arranged around the display part 16 and is provided with a scale 18 in the longitudinal direction of the color changing part 24.

Description

この発明は、ストレスやリフレッシュ効果等の心身の状態の測定、皮膚の各部位やその他の水分蒸発量測定のための水分蒸散量測定パッチに関する。   The present invention relates to a moisture transpiration amount measurement patch for measuring a state of mind and body such as stress and a refreshing effect, and for measuring each part of the skin and other moisture evaporation.

例えば、皮膚からの水分蒸発の種類には、ストレス等の精神的な刺激により、交感神経の働きによって手の平や足の裏から精神性の汗が分泌されることが知られている。この精神性発汗は運動による汗である温熱性発汗と異なり、極めて微量で数mg/cm/hrから数10mg/cm/hrの範囲である。この発汗により、経皮水分蒸発量(Trance Epidermal Water Loss、以下TEWL値と称す)は増加する。この現象から、TEWL値を測定することによって、ストレス等を調べることができる。 For example, it is known that the type of moisture evaporation from the skin causes mental sweat to be secreted from the palms and soles of the palm by the action of sympathetic nerves due to mental stimulation such as stress. This mental sweating is in a very small amount in the range of several mg / cm 2 / hr to several tens mg / cm 2 / hr, unlike thermal sweating which is sweat due to exercise. This perspiration increases the amount of transdermal water evaporation (Trance Epidermal Water Loss, hereinafter referred to as TEWL value). From this phenomenon, stress or the like can be examined by measuring the TEWL value.

皮膚からの水分蒸散量を連続的に測定する機器としてはTEWAメータ、エバポリメータなどが市販されているが、高価であり、大型で重く測定用のセンサーを長時間皮膚などの測定部位に固定することが必要であった。更に、目的の作業を行いながら測定することは困難であり、長時間の連続的な測定の場合には記録計が必要となるため、測定作業が被験者の負担になるものであった。このため、皮膚からの水分蒸散量の測定は、研究機関等での限定的なものに限られ、一般的ではなかった。   TEWA meters, evaporation polymeters, etc. are commercially available as instruments that continuously measure the amount of moisture transpiration from the skin, but they are expensive, large and heavy, and the measurement sensor must be fixed to the measurement site such as the skin for a long time. Was necessary. Furthermore, it is difficult to perform measurement while performing a target operation, and a recorder is required in the case of continuous measurement over a long period of time. For this reason, the measurement of the amount of moisture transpiration from the skin is limited to a limited one at a research institution and is not general.

そこで従来、TEWL値を簡単に測定し、ストレスの度合いを調べる試験シートが提供されている。本願発明者による特許文献1,2に開示されている試験シートは、粘着剤により皮膚に貼付される透明フィルムと、透明フィルムの粘着剤側の面に設けられ塩化コバルトを吸着させた塩化コバルト紙が設けられている。透明フィルムには、塩化コバルトが吸湿により反応する発色の色見本が設けられている。この試験シートの使用方法は、被験者の皮膚に貼り付け、皮膚の表面から蒸散する水分を塩化コバルト紙が吸湿して、吸着水分によって塩化コバルトの結晶構造が変化することによって色が変化するものである。この色の変化を、色見本と比較することにより蒸散する水分量を測定するものである。   Thus, conventionally, a test sheet for simply measuring the TEWL value and checking the degree of stress has been provided. The test sheet disclosed in Patent Documents 1 and 2 by the inventor of the present application includes a transparent film attached to the skin with an adhesive, and a cobalt chloride paper that is provided on the adhesive side of the transparent film and adsorbs cobalt chloride. Is provided. The transparent film is provided with a color sample for coloring in which cobalt chloride reacts by moisture absorption. The test sheet is applied to the skin of the subject, and the color changes as the cobalt chloride paper absorbs moisture that evaporates from the skin surface and the cobalt chloride crystal structure changes due to the adsorbed moisture. is there. The amount of water that evaporates is measured by comparing this color change with a color sample.

特開2004−236794号公報JP 2004-236794 A 特開2007−147449号公報JP 2007-147449 A

上記背景技術の場合、塩化コバルトの変色により水分量を定性的に測定するものであり、水分蒸発量を定量的に正確に測定することができるものではなかった。従って、簡単なパッチ等により、水分蒸散量をより正確に定量的に測定することができれば、種々の生活の場におけるQOL向上に役立つと考えられる。   In the case of the above background art, the amount of water is qualitatively measured by the discoloration of cobalt chloride, and the amount of water evaporation cannot be measured quantitatively and accurately. Therefore, if the amount of water transpiration can be measured more accurately and quantitatively with a simple patch or the like, it is considered useful for improving QOL in various places of life.

また、市販されているストレスや皮膚水分蒸散量を測定するための機器は高価であり、連続的な測定は不可能であり、実験的な測定に限られるものであった。   In addition, commercially available instruments for measuring stress and skin moisture transpiration are expensive, continuous measurement is impossible, and the measurement is limited to experimental measurement.

この発明は、上記背景技術の問題点に鑑みてなされたものであり、簡単な構造で、皮膚等の測定対象表面に貼るだけの簡単な操作で水分蒸散量を正確に定量的に測定することができる水分蒸散量測定パッチを提供することを目的とする。   The present invention has been made in view of the above-mentioned problems of the background art, and has a simple structure and accurately and quantitatively measures the amount of water transpiration with a simple operation that is applied to the surface of a measurement object such as skin. It is an object of the present invention to provide a patch for measuring moisture transpiration.

本発明は、粘着剤により皮膚等の測定対象表面に貼付される透明フィルムと、上記透明フィルムの粘着剤側の面に設けられ発色剤を吸着させた発色剤貯蔵部と、前記発色剤貯蔵部に連なり一方向に長く形成され前記発色剤の溶解液が長手方向に浸透する変色部と、前記変色部の前記透明フィルム側と反対側の面を覆う水分不透過層と、上記透明フィルムの粘着剤側の面に対面し前記発色剤貯蔵部を覆う水分透過層が設けられ、前記透明フィルムには前記変色部を視認可能にする透明な表示部と、前記表示部の周辺部に設けられ前記変色部の長手方向に沿う目盛が描かれた印刷部が設けられている水分蒸散量測定パッチである。   The present invention includes a transparent film that is attached to a surface to be measured such as skin with an adhesive, a color former storage unit that is provided on the adhesive side of the transparent film and adsorbs the color former, and the color former storage unit. A color-changing portion that is formed long in one direction and that penetrates in the longitudinal direction, a moisture-impermeable layer that covers the surface of the color-changing portion opposite to the transparent film, and an adhesive for the transparent film A moisture permeable layer facing the surface of the colorant and covering the color former storage part is provided, and the transparent film has a transparent display part that makes the discolored part visible, and a peripheral part of the display part. It is a moisture transpiration amount measurement patch provided with a printing part on which a scale along the longitudinal direction of the discoloration part is drawn.

また、前記変色部は複数設けられ、前記変色部に各々前記発色剤貯蔵部が設けられ、複数の前記変色部は互いに重ねられて前記表示部に対面し、前記重ねられた複数の変色部は、相対的に前記表示部に近い側に位置した前記変色部が前記表示部に対して遠い側に位置した前記変色部より長手方向に短く形成され、前記各変色部同士の間には水分不透過層が設けられ、複数個の前記発色剤貯蔵部には、互いに異なる色の発色剤が吸着されているものである。   In addition, a plurality of the color changing portions are provided, and each of the color changing portions is provided with the color former storage portion, and the plurality of the color changing portions are overlapped with each other so as to face the display portion. The discoloration part positioned relatively closer to the display part is formed shorter in the longitudinal direction than the discoloration part located farther from the display part, and there is no moisture between the discoloration parts. A transmissive layer is provided, and the color formers having different colors are adsorbed to the plurality of color former reservoirs.

前記発色剤貯蔵部には、前記発色剤の溶解・浸透速度を早める溶解促進剤として親水性高分子材料を混合したものである。前記発色剤貯蔵部には、前記発色剤の溶解・浸透速度を速める界面活性剤を混合したものである。前記親水性高分子材料は、例えばポリエチレングリコールである。前記変色部と前記発色剤貯蔵部及び表示部は、各々複数設けられているものでも良い。また、前記変色部と前記発色剤貯蔵部は、同一のシート材により形成され、前記発色剤貯蔵部は乾燥した固体の材料である。   In the color former storage section, a hydrophilic polymer material is mixed as a dissolution accelerator for increasing the dissolution / penetration rate of the color former. In the color former storage section, a surfactant that accelerates the dissolution / penetration rate of the color former is mixed. The hydrophilic polymer material is, for example, polyethylene glycol. A plurality of the color changing section, the color former storage section, and the display section may be provided. Further, the color changing portion and the color former storage portion are formed of the same sheet material, and the color former storage portion is a dry solid material.

本発明の水分蒸散量測定パッチは、皮膚等の測定対象表面に貼付することによって水分蒸散量を、簡単に正確に定量的に測定することが可能である。そして、測定対象表面である皮膚等から、例えば不感蒸散水分量や手の平の発汗量の測定によってストレス・興奮・痛み等の精神的な刺激等を数量化することが可能となる。   The moisture transpiration amount measurement patch of the present invention can measure the amount of moisture transpiration easily, accurately and quantitatively by applying it to the surface of the measurement object such as the skin. It is possible to quantify mental stimuli such as stress, excitement, and pain from the skin or the like that is the measurement target surface by measuring, for example, the amount of insensitive transpiration water or the amount of sweating on the palm.

この発明の第一実施形態の水分蒸散量測定パッチの横断面模式図である。It is a cross-sectional schematic diagram of the moisture transpiration amount measurement patch of 1st embodiment of this invention. この発明の第一実施形態の水分蒸散量測定パッチの正面図である。It is a front view of the moisture transpiration amount measurement patch of the first embodiment of the present invention. この発明の第一実施形態の水分蒸散量測定パッチの背面図である。It is a rear view of the moisture transpiration amount measurement patch of the first embodiment of the present invention. この発明の第一実施形態の水分蒸散量測定パッチの変形例を示す正面図である。It is a front view which shows the modification of the moisture transpiration amount measurement patch of 1st embodiment of this invention. この発明の第一実施形態の水分蒸散量測定パッチのパッチ目盛とTEWL測定値の相関性を示すグラフである。It is a graph which shows the correlation of the patch scale and TEWL measurement value of the moisture transpiration amount measurement patch of 1st embodiment of this invention. この発明の第二実施形態の水分蒸散量測定パッチの拡大横断面模式図である。It is an expansion cross-sectional schematic diagram of the moisture transpiration amount measurement patch of 2nd embodiment of this invention. この発明の第二実施形態の水分蒸散量測定パッチの背面図である。It is a rear view of the moisture transpiration amount measurement patch of a second embodiment of the present invention.

以下、この発明の実施形態について図面に基づいて説明する。図1〜図3はこの発明の第一実施形態を示すもので、この実施形態の水分蒸散量測定パッチ10は、その支持体となる透明フィルム12が設けられている。透明フィルム12の素材は柔軟性を有し透明性に優れ、また強靭性にも優れた樹脂フィルムで作られている。例えば、ポリプロピレン、ポリオレフィン、ポリエステル、ポリ塩化ビニル、ポリ塩化ビニリデン、ポリエチレン、ナイロン、ウレタン等が使用される。厚さは、20〜100ミクロンであり、好ましくは50〜75ミクロンである。透明フィルム12は、長方形の角を丸めた形状又は長丸や円形に切断されている。   Hereinafter, embodiments of the present invention will be described with reference to the drawings. 1 to 3 show a first embodiment of the present invention, and a moisture transpiration measuring patch 10 of this embodiment is provided with a transparent film 12 serving as a support. The material of the transparent film 12 is made of a resin film having flexibility, excellent transparency, and excellent toughness. For example, polypropylene, polyolefin, polyester, polyvinyl chloride, polyvinylidene chloride, polyethylene, nylon, urethane and the like are used. The thickness is 20 to 100 microns, preferably 50 to 75 microns. The transparent film 12 is cut into a shape with rounded rectangular corners, or an oval or a circle.

透明フィルム12の表面12aには、所定の文字や絵柄が描かれた印刷部14が設けられている。図2は、水分蒸散量測定パッチ10の透明フィルム12の表面12aから見た印刷部14を示したものであり、透明フィルム12の表面12aの中心には、透明な表示部16が設けられている。表示部16の内側には、透明フィルム12を透過し、透明フィルム12の裏面12bに設けられた後述する変色部24が視認される。表示部16の形状は、透明フィルム12の長手方向に沿う長い矩形である。表示部16の長手方向に沿う一方の側縁部には、水分蒸散量を示す目盛18が印刷され、他方の側縁部には目盛18に対応する水分蒸散量の状態が5段階で、「非常に良好」「やや良好」「普通」「やや乾燥」「乾燥」という文字20で印刷されている。   On the surface 12a of the transparent film 12, a printing unit 14 on which predetermined characters and patterns are drawn is provided. FIG. 2 shows the printing unit 14 as seen from the surface 12a of the transparent film 12 of the moisture transpiration measurement patch 10. A transparent display unit 16 is provided at the center of the surface 12a of the transparent film 12. Yes. Inside the display portion 16, a color changing portion 24 described later provided on the back surface 12 b of the transparent film 12 through the transparent film 12 is visually recognized. The shape of the display unit 16 is a long rectangle along the longitudinal direction of the transparent film 12. On one side edge along the longitudinal direction of the display unit 16, a scale 18 indicating the amount of moisture transpiration is printed, and on the other side edge, the state of the amount of moisture transpiration corresponding to the scale 18 has five levels. The characters 20 are printed as “very good”, “slightly good”, “normal”, “slightly dry”, and “dry”.

透明フィルム12の裏面12bには粘着剤22が均一に取り付けられている。粘着剤22は、例えばアクリル系粘着剤である。そして、透明フィルム12の裏面12bには、表示部16に対向する位置に変色部24が設けられている。変色部24は、ろ紙や和紙、レーヨンその他のセルロース系の親水性材料のシート材を所定形状に裁断したものであり、白色等の薄い色である。変色部24は表示部16の長手方向よりも長く、幅方向も広い矩形に設けられている。変色部24は、表示部16の「非常に良好」と印刷されている端部よりも所定長さに突出して設けられ、突出した部分は発色剤貯蔵部26となる。   An adhesive 22 is uniformly attached to the back surface 12 b of the transparent film 12. The adhesive 22 is, for example, an acrylic adhesive. A color changing portion 24 is provided on the back surface 12 b of the transparent film 12 at a position facing the display portion 16. The discoloration portion 24 is obtained by cutting a sheet material of filter paper, Japanese paper, rayon or other cellulose-based hydrophilic material into a predetermined shape, and has a light color such as white. The color changing portion 24 is provided in a rectangular shape that is longer than the longitudinal direction of the display portion 16 and wider in the width direction. The discoloration portion 24 is provided so as to protrude to a predetermined length from the end portion of the display portion 16 printed with “very good”, and the protruding portion becomes the color former storage portion 26.

発色剤貯蔵部26には、発色剤28が吸着され乾燥されている。発色剤28は水溶性であり、顔料、染料から選ばれた1種または複数種類を混合し、目視判定に適した色から選ばれる。色は、赤、青、黄色、緑等である。例えば赤の発色剤は、アマランス、エリスロシン、アルラレッド、ニューコクシン等である。青の発色剤は、インジコカーミン、ブリリアントブルー等である。黄色の発色剤は、タートラジン、サンセットイエロー等である。また、これらの混合によって任意の色を調整することができる。例えば、緑色は青色と黄色の混合、オレンジ色は赤色と黄色の混合により形成することができる。   The color former 28 is adsorbed and dried in the color former reservoir 26. The color former 28 is water-soluble, and is selected from colors suitable for visual determination by mixing one or more selected from pigments and dyes. The colors are red, blue, yellow, green and the like. For example, red color formers include amaranth, erythrosin, allura red, and new coxin. Examples of the blue color former include indigo carmine and brilliant blue. Examples of the yellow color former include tartrazine and sunset yellow. Moreover, arbitrary colors can be adjusted by mixing these. For example, green can be formed by mixing blue and yellow, and orange can be formed by mixing red and yellow.

発色剤28には、溶解促進剤29が混合されている。溶解促進剤29により、発色剤28の吸着水分への溶解と変色部への浸透速度は著しく速くなる。溶解促進剤29は水溶性のものであり、潮解性物質や親水性高分子材料、又は界面活性剤から選ばれた1種又は複数種が使用される。例えば、ソルビトール、ポリエチレングリコール、グリセリン、塩化アンモニウム、塩化カルシウム等である。特にポリエチレングリコールは、毒性が低く、化学変化しにくい特徴があるので有効である。ポリエチレングリコールは、その平均分子量は1000〜20000のものがよく、特に好ましくは1000〜4000の材料がよい。   A dissolution accelerator 29 is mixed with the color former 28. Due to the dissolution accelerator 29, the dissolution rate of the color former 28 in the adsorbed moisture and the penetration rate into the discolored portion are remarkably increased. The dissolution accelerator 29 is water-soluble, and one or more kinds selected from a deliquescent substance, a hydrophilic polymer material, or a surfactant are used. For example, sorbitol, polyethylene glycol, glycerin, ammonium chloride, calcium chloride and the like. In particular, polyethylene glycol is effective because it has low toxicity and is difficult to chemically change. The average molecular weight of polyethylene glycol is preferably 1000 to 20000, and particularly preferably 1000 to 4000.

溶解促進剤29として、親水性高分子材料や界面活性剤は、発色剤28の溶解を促進し、変色部24への浸透を早めるので有効である。親水性高分子材料としてはポリエチレングリコールやポリビニルアルコール、界面活性剤としては、非イオン系界面活性剤が好ましく、しょ糖脂肪酸エステルソルビタン脂肪酸エステル、ポリオキシエチレンソルビタン脂肪酸エステル、脂肪酸ソルビタンエステル、脂肪酸アルカノールアミド、脂肪酸ジエタノールアミド、ポリオキシエチレンアルキルエーテル、ポリオキシエチレンアルキルフェニルエーテル、アルキルポリグリコシド、アルキルモノグリセリルエーテル等がある。   As the dissolution accelerator 29, a hydrophilic polymer material or a surfactant is effective because it accelerates the dissolution of the color former 28 and accelerates the penetration into the discolored portion 24. As the hydrophilic polymer material, polyethylene glycol or polyvinyl alcohol, and as the surfactant, a nonionic surfactant is preferable, sucrose fatty acid ester sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, fatty acid sorbitan ester, fatty acid alkanolamide, Examples include fatty acid diethanolamide, polyoxyethylene alkyl ether, polyoxyethylene alkyl phenyl ether, alkyl polyglycoside, and alkyl monoglyceryl ether.

変色部24の、透明フィルム12と反対側の面には、水分不透過層30が変色部24を覆って設けられている。水分不透過層30は変色部24よりもわずかに大きいものである。変色部24に連なる発色剤貯蔵部26は、水分不透過層30の端部から外側に突出し露出している。水分不透過層30は、例えばポリプロピレン等のフィルムである。水分不透過層30の、変色部24と反対側の面には、粘着剤32が均一に塗布されている。粘着剤32は、例えばアクリル系粘着剤である。   A moisture-impermeable layer 30 is provided on the surface of the color changing portion 24 opposite to the transparent film 12 so as to cover the color changing portion 24. The moisture impermeable layer 30 is slightly larger than the discolored portion 24. The color former storage portion 26 connected to the color changing portion 24 protrudes outward from the end portion of the moisture-impermeable layer 30 and is exposed. The moisture impermeable layer 30 is a film such as polypropylene, for example. An adhesive 32 is uniformly applied to the surface of the moisture impermeable layer 30 opposite to the discolored portion 24. The adhesive 32 is, for example, an acrylic adhesive.

透明フィルム12の裏面12bには、発色剤貯蔵部26を覆う水分透過層34が設けられている。水分透過層34は、透明フィルム12よりも小さい形状で、少なくとも発色剤貯蔵部26の全体を覆う大きさである。水分透過層34の接着は、水分透過層34の水分不透過層30に接する所は粘着剤32に、透明フィルム12に接する所は粘着剤22により貼り付けられている。水分透過層34は、ポリエステル、ポリプロピレン等の疎水性の不織布または織布である。   On the back surface 12 b of the transparent film 12, a moisture permeable layer 34 that covers the color former storage unit 26 is provided. The moisture permeable layer 34 is smaller than the transparent film 12 and has a size that covers at least the entire color former storage unit 26. The moisture permeable layer 34 is adhered to the adhesive 32 where the moisture permeable layer 34 contacts the moisture impermeable layer 30 and the adhesive 22 where it contacts the transparent film 12. The moisture permeable layer 34 is a hydrophobic nonwoven fabric or woven fabric such as polyester or polypropylene.

透明フィルム12の裏面12bには、水分透過層34を覆って、剥離シート36が貼り合わされている。剥離シート36が取り付けられた水分蒸散量測定パッチ10は、図示しない樹脂フィルム等の袋に包装され、密封されている。これによって空気中の湿度による変質を防ぐことができる。   A release sheet 36 is bonded to the back surface 12 b of the transparent film 12 so as to cover the moisture permeable layer 34. The moisture transpiration amount measurement patch 10 to which the release sheet 36 is attached is packaged and sealed in a bag such as a resin film (not shown). As a result, alteration due to humidity in the air can be prevented.

次に、この実施形態の水分蒸散量測定パッチ10の使用方法について説明する。まず、水分蒸散量測定パッチ10から剥離シート36を剥がし、粘着剤22を露出させる。そして、被験者の皮膚、例えば手の平に水分蒸散量測定パッチ10を貼り付ける。このとき、水分蒸散量測定パッチ10を貼り付ける前に、手の平の汗や手洗い等で濡れた水分を予め拭き取る。貼付後その状態で、所定時間放置する。貼付時間は、数分〜24時間であり、例えば3分間でもよい。このとき、発生する手の平の汗を水分透過層34が捉え、その水分を発色剤貯蔵部26が吸着して発色剤28が溶け、変色部24に浸透して着色した水分が変色部24を移動する。吸着する水分が多いほど発色剤貯蔵部26から浸透する水分が多くなり、変色部24の着色領域での到達距離が長くなる。所定時間経過後、変色部24の色の到達距離を表示部16から見て、目盛18と比較して水分蒸散量を測定する。測定範囲は、ここでは0〜5mg/cmである。測定範囲は、変色部24の形状や大きさ、厚さ等を調整して数μg/cm〜100mg/cm程度の任意の値に設定することができる。 Next, a method of using the moisture transpiration amount measurement patch 10 of this embodiment will be described. First, the release sheet 36 is peeled from the moisture transpiration amount measurement patch 10 to expose the adhesive 22. Then, the moisture transpiration measurement patch 10 is attached to the skin of the subject, for example, the palm. At this time, before applying the moisture transpiration amount measurement patch 10, wet moisture is wiped off in advance by sweating of the palm or hand washing. After sticking, leave it in that state for a predetermined time. The sticking time is several minutes to 24 hours, and may be, for example, 3 minutes. At this time, the moisture permeation layer 34 captures the palm sweat that is generated, the color developer storage unit 26 adsorbs the moisture, the color developer 28 melts, and the colored moisture penetrates into the color changing portion 24 and moves through the color changing portion 24. To do. The more moisture that is adsorbed, the more moisture that permeates from the color former reservoir 26 and the longer the reach of the color changing portion 24 in the colored region. After a predetermined time has elapsed, the color reach of the color changing section 24 is viewed from the display section 16 and compared with the scale 18 to measure the amount of moisture transpiration. The measurement range here is 0-5 mg / cm 2 . The measurement range can be set to an arbitrary value of about several μg / cm 2 to 100 mg / cm 2 by adjusting the shape, size, thickness, and the like of the color changing portion 24.

水分蒸散量測定パッチ10の水分蒸散量の測定時間、反応速度、測定範囲等は、変色部24の形状や面積を適宜選択することによって任意に調整することができる。変色部24の面積を大きくすることによって測定時間を長く、例えば12時間〜24時間に設定し、長時間の測定が可能となる。また、水分透過層34の面積により吸着速度を調節することができる。水分透過層34の面積を大きくすると反応速度は速くなり、面積を小さくすれば遅くなる。水分透過層34の面積を大きくすることによって吸着水分量が増えるので測定感度は高くなり、測定時間を短くすることができる。変色部24の厚さ及び面積の組み合わせによっても吸着速度を任意に調整することが可能であり、厚く又は面積を大きくすると反応速度は遅くなる。   The measurement time, reaction rate, measurement range, and the like of the moisture transpiration amount of the moisture transpiration amount measurement patch 10 can be arbitrarily adjusted by appropriately selecting the shape and area of the color changing portion 24. By increasing the area of the color changing portion 24, the measurement time is set longer, for example, set to 12 hours to 24 hours, and long time measurement is possible. Further, the adsorption rate can be adjusted by the area of the moisture permeable layer 34. Increasing the area of the moisture permeable layer 34 increases the reaction rate, and decreasing the area decreases it. By increasing the area of the moisture permeable layer 34, the amount of adsorbed moisture increases, so that the measurement sensitivity increases and the measurement time can be shortened. The adsorption rate can be arbitrarily adjusted by the combination of the thickness and area of the color changing portion 24, and the reaction rate becomes slow when the thickness or area is increased.

この実施形態の水分蒸散量測定パッチ10は、皮膚に貼付することによって水分蒸散量を正確に定量することが可能であり低コストで、手軽に測定することができる。精神性発汗は、ストレス・興奮・痛み等の精神的な刺激の度合いに比例して分泌されるので、この発汗量を定量的に調べることによって、これらのストレス・興奮・痛み等の精神的な刺激を数量化することが可能となる。例えば、水分蒸散量測定パッチ10を手の平等に貼付し、自動車運転や日常の作業、危険作業等に従事する時に、発汗量を定量することによってストレスの度合いを数値化することが可能となる。さらに、水分蒸散量測定パッチ10を長時間貼り、その間の種々の作業や生活等個々の行動の単位時間当たりの発汗量を調べることによってどの作業や生活等からどれだけの精神的ストレスを受けているか容易に分析することが可能になる。その他、長時間の積算水分量を測定することもできる。   The moisture transpiration amount measurement patch 10 of this embodiment can accurately measure the amount of moisture transpiration by being applied to the skin, and can be easily measured at low cost. Mental sweating is secreted in proportion to the degree of mental stimulation such as stress, excitement, and pain. By quantitatively examining the amount of sweating, mental sweating such as stress, excitement, and pain Stimulation can be quantified. For example, when the moisture transpiration amount measurement patch 10 is affixed to the palm of the hand and engaged in car driving, daily work, dangerous work, etc., the amount of sweat can be quantified to quantify the degree of stress. Furthermore, by applying the moisture transpiration measuring patch 10 for a long time, and by examining the amount of perspiration per unit time of various actions such as various work and life, how much mental stress is received from which work and life. It becomes possible to analyze easily. In addition, it is possible to measure the accumulated moisture amount for a long time.

また、水分蒸散量測定パッチ10は、医療機関で、治療や検査の間に感じる患者の痛みや不安から生じるストレスを、治療中または長時間連続的に測定することができる。また、学校や職場での生徒や社員間の人間関係、いじめによるストレスを測定することができ、また一般の人が自分の心の状態をセルフチェックすることができる。これにより、QOL(生活の質)向上に役立つ。   In addition, the moisture transpiration measurement patch 10 can measure stress caused by pain and anxiety of a patient during treatment or examination at a medical institution during treatment or continuously for a long time. In addition, it is possible to measure the relationship between students and employees at school and workplaces, the stress caused by bullying, and the general public can self-check their own state of mind. This helps to improve QOL (quality of life).

さらに、精神性発汗の他に、不感蒸散を測定して皮膚のバリア機能、スキンケアの効果、保湿力、肌荒れのチェックを行うことができる。また、手足や背中、腹部等全身の温熱性発汗を測定して、不汗症や寝汗等のチェックを行うことができる。これは、皮膚科の医師や美容の専門家による診断に使用でき、また一般の人が自分の皮膚の状態を自宅や職場などいつでも定量測定することができる。   Furthermore, in addition to mental sweating, insensitive transpiration can be measured to check the skin barrier function, skin care effect, moisturizing power, and rough skin. In addition, thermal sweating of the whole body such as limbs, back, and abdomen can be measured to check for non-hidrosis and night sweats. This can be used for diagnosis by dermatologists and beauty specialists, and the general public can quantitatively measure their skin condition at home or at any time.

水分蒸散量測定パッチ10は絆創膏状のパッチであり、測定セルや測定機械、記録機器、パソコンなどの機械類が不要であり、測定が極めて容易で違和感が無く、簡便であり、一定時間のTEWL値の積算、不感蒸散量、各部位の水分蒸散量、睡眠時の寝汗などの測定が容易である。また、複数か所を同時に測定することができる。また、皮膚の任意の部位に貼付することによって、貼付部位の水分蒸散量を連続的に長時間にわたって測定することが可能である。   Moisture transpiration measurement patch 10 is a bandage-like patch that requires no measuring cell, measuring machine, recording device, personal computer, etc., is extremely easy to measure, has no sense of incongruity, is simple, and has a constant TEWL. It is easy to measure values such as integration of values, insensitive transpiration, moisture transpiration at each site, and night sweats during sleep. In addition, a plurality of locations can be measured simultaneously. Moreover, it is possible to continuously measure the amount of moisture transpiration at the applied site over a long period of time by applying it to an arbitrary site on the skin.

水分蒸散量測定パッチ10の印刷部14は、上記以外でもよく、例えば図4に示すように目盛18に0mg/cm〜5mg/cmの数値を印刷してもよい。測定範囲は、目盛18に対応する0〜5mg/cmである。測定範囲は、変色部24の形状や大きさ、厚さ等を調整して数μg/cm〜100mg/cm程度の任意の値に設定することができる。 Printing unit 14 of the water loss measurement patch 10 may print the value of 0mg / cm 2 ~5mg / cm 2 in the memory 18 as may be other than the above is shown in FIG. 4, for example. The measurement range is 0 to 5 mg / cm 2 corresponding to the scale 18. The measurement range can be set to an arbitrary value of about several μg / cm 2 to 100 mg / cm 2 by adjusting the shape, size, thickness, and the like of the color changing portion 24.

この実施形態では、本発明の水分蒸散量測定パッチの精度を調べるために、水分蒸散量測定パッチ10で目盛18から測定した値と、TEWAメータにより測定したTEWL値との相関性を調べた。水分蒸散量測定パッチ10を22歳から46歳の男女6人の前腕に貼付し、室温22±1℃、湿度55%の室内で5時間測定した。測定は、一定時間の目盛の変化量(mm)の記録と同時にTEWAメータによりTEWL値(g/m)を測定した。その結果を図5のグラフに示す。これによると、水分蒸散量測定パッチ10の目盛18の変化量とTEWL値の間に有意な相関のあることを認めた。 In this embodiment, in order to examine the accuracy of the moisture transpiration measurement patch of the present invention, the correlation between the value measured from the scale 18 by the moisture transpiration measurement patch 10 and the TEWL value measured by the TEWA meter was examined. The moisture transpiration measurement patch 10 was affixed to the forearms of 6 men and women aged 22 to 46 and measured for 5 hours in a room with a room temperature of 22 ± 1 ° C. and a humidity of 55%. In the measurement, the TEWL value (g / m 2 ) was measured with the TEWA meter simultaneously with the recording of the change amount (mm) of the scale for a certain time. The results are shown in the graph of FIG. According to this, it was recognized that there was a significant correlation between the amount of change of the scale 18 of the moisture transpiration measurement patch 10 and the TEWL value.

次にこの発明の第二実施形態について図6、図7に基づいて説明する。ここで、上記実施形態と同様の部材は同様の符号を付して説明を省略する。この実施形態の水分蒸散量測定パッチ38は、その支持体となる透明フィルム12が設けられている。透明フィルム12の表面12aには、所定の絵柄が印刷される印刷部14が設けられ、透明フィルム12の表面12aの中心には、透明な表示部16が設けられている。   Next, a second embodiment of the present invention will be described with reference to FIGS. Here, the same members as those in the above embodiment are denoted by the same reference numerals, and description thereof is omitted. The moisture transpiration amount measurement patch 38 of this embodiment is provided with a transparent film 12 as a support. A printing unit 14 on which a predetermined pattern is printed is provided on the surface 12 a of the transparent film 12, and a transparent display unit 16 is provided at the center of the surface 12 a of the transparent film 12.

透明フィルム12の裏面12bには粘着剤22が均一に塗布されている。そして、裏面12bには、表示部16の一方の端部を覆って第一変色部39が設けられている。第一変色部39は、ろ紙や和紙、その他のセルロース系のシートを所定形状にカットしたものであり、表示部16の長手方向よりも短く、例えば約半分の長さに設定され、幅方向は表示部16よりも広い矩形に設定されている。第一変色部39は、表示部16の一端部から所定長さに突出して設けられ、突出した部分は第一発色剤貯蔵部40となる。第一発色剤貯蔵部40には、発色剤41が吸着され乾燥されている。   An adhesive 22 is uniformly applied to the back surface 12 b of the transparent film 12. A first color changing portion 39 is provided on the back surface 12 b so as to cover one end portion of the display portion 16. The first color changing portion 39 is obtained by cutting filter paper, Japanese paper, or other cellulosic sheets into a predetermined shape, which is shorter than the longitudinal direction of the display portion 16, for example, is set to about half the length, and the width direction is It is set to a rectangle wider than the display unit 16. The first color changing portion 39 is provided so as to protrude from the one end portion of the display portion 16 to a predetermined length, and the protruding portion becomes the first color former storage portion 40. The color former 41 is adsorbed and dried in the first color former storage section 40.

第一変色部39の、透明フィルム12と反対側の面には、第二変色部42が設けられている。第二変色部42は、第一変色部39の途中から表示部16に沿って表示部16の先端部を超えて設けられ、幅方向には第一変色部39よりも広い矩形に設定されている。第二変色部42の第一変色部39に対応した途中から第一発色剤貯蔵部40との境界までの領域が、第二発色剤貯蔵部44となる。第二発色剤貯蔵部44には、第一変色部39の発色剤41とは色が異なる発色剤43が吸着され乾燥されている。第二発色剤貯蔵部44と、第一発色剤貯蔵部40は、互いに位置がずれて後述する水分透過層52に露出しているため、水分透過層52が捉えた水分を、第一発色剤貯蔵部40と第二発色剤貯蔵部44が同時に吸湿する。各発色剤41,43には、溶解促進剤29(溶解補助剤・溶解促進剤)が混合されている。   A second color changing portion 42 is provided on the surface of the first color changing portion 39 opposite to the transparent film 12. The second color changing section 42 is provided from the middle of the first color changing section 39 along the display section 16 beyond the tip of the display section 16, and is set to a rectangle wider than the first color changing section 39 in the width direction. Yes. A region from the middle corresponding to the first color changing portion 39 of the second color changing portion 42 to the boundary with the first color developing agent storage portion 40 becomes the second color forming agent storage portion 44. A color former 43 having a color different from that of the color former 41 of the first color changing section 39 is adsorbed and dried in the second color former storage section 44. Since the second color former storage unit 44 and the first color developer storage unit 40 are displaced from each other and exposed to the moisture permeable layer 52 described later, the moisture captured by the moisture permeable layer 52 is transferred to the first color developer. The storage unit 40 and the second color former storage unit 44 absorb moisture simultaneously. Each of the color formers 41 and 43 is mixed with a dissolution accelerator 29 (dissolution aid / dissolution accelerator).

互いに重ねられた第一変色部39・第一発色剤貯蔵部40と第二変色部42・第二発色剤貯蔵部44の間には、粘着剤50が塗布された透明な水分不透過層46が設けられ、互いの発色剤41,43が混ざることを防いでいる。水分不透過層46は、透明フィルム12の一端部近傍まで延びている。第二変色部42の、水分不透過層46と反対側の面には、水分不透過層48が設けられ、水分不透過層48の端部も、透明フィルム12の一端部近傍まで延びている。第二変色部42に連続する第二発色剤貯蔵部44は、水分不透過層48の端部から外側に突出し露出している。水分不透過層48の、第二変色部42と反対側の面には、粘着剤50が均一に取り付けられている。   A transparent moisture-impermeable layer 46 coated with an adhesive 50 is interposed between the first color change portion 39 and the first color change agent storage portion 40 and the second color change portion 42 and the second color change agent storage portion 44 that are stacked on each other. Is provided to prevent the color formers 41 and 43 from being mixed. The moisture impermeable layer 46 extends to the vicinity of one end of the transparent film 12. A moisture-impermeable layer 48 is provided on the surface of the second color changing portion 42 opposite to the moisture-impermeable layer 46, and the end of the moisture-impermeable layer 48 extends to the vicinity of one end of the transparent film 12. . The second color former storage section 44 continuous with the second color changing section 42 protrudes outward from the end of the moisture impermeable layer 48 and is exposed. A pressure-sensitive adhesive 50 is uniformly attached to the surface of the moisture impermeable layer 48 opposite to the second discoloration portion 42.

透明フィルム12の裏面12bには、第二発色剤貯蔵部44を覆う水分透過層52が設けられている。水分透過層52は、透明フィルム12よりも小さい形状で、第二変色部42と第二発色剤貯蔵部44を覆う大きさである。水分透過層52の水分不透過層48に接する所は粘着剤50に、透明フィルム12に接する所は粘着剤22により貼り付けられている。さらに、透明フィルム12の裏面12bには、水分透過層52を覆って、剥離シート36が粘着剤22により貼り合わされている。   A moisture permeable layer 52 that covers the second color former storage unit 44 is provided on the back surface 12 b of the transparent film 12. The moisture permeable layer 52 is smaller than the transparent film 12 and has a size covering the second color changing portion 42 and the second color former storage portion 44. The portion of the moisture permeable layer 52 that is in contact with the moisture impermeable layer 48 is attached to the adhesive 50, and the portion that is in contact with the transparent film 12 is attached to the adhesive film 22. Further, the release sheet 36 is bonded to the back surface 12 b of the transparent film 12 with the adhesive 22 so as to cover the moisture permeable layer 52.

次に、この実施形態の水分蒸散量測定パッチ38の使用方法について説明する。まず、水分蒸散量測定パッチ38から剥離シート36を剥がし、粘着剤22を露出させる。そして、被験者の皮膚、例えば手の平に水分蒸散量測定パッチ38を貼り付ける。貼付後その状態で所定時間放置する。このとき、発生する手の平の汗を水分透過層52が捉え、その水分を第一発色剤貯蔵部40、第二発色剤貯蔵部44が吸着して発色剤41,43が溶け、第一変色部39、第二変色部42に浸透して拡散する。第一発色剤貯蔵部40、第二発色剤貯蔵部44の間には水分不透過層46が設けられているため、発色剤41,43は混ざることがない。発色剤41,43は吸着する水分が多いほど第一発色剤貯蔵部40、第二発色剤貯蔵部44からの到達距離が長くなる。第一変色部39、第二変色部42の水分吸着速度は等しくても良いが、両者に差を持たせて、例えば第二変色部42の水分吸着速度を遅くしても良い。   Next, a method of using the moisture transpiration amount measurement patch 38 of this embodiment will be described. First, the release sheet 36 is peeled from the moisture transpiration measurement patch 38 to expose the adhesive 22. Then, the moisture transpiration measuring patch 38 is attached to the skin of the subject, for example, the palm. After sticking, leave it in that state for a predetermined time. At this time, the moisture permeable layer 52 captures the palm sweat generated, and the moisture is absorbed by the first color former storage unit 40 and the second color developer storage unit 44 so that the color formers 41 and 43 are melted. 39, penetrates and diffuses into the second color changing portion 42. Since the moisture-impermeable layer 46 is provided between the first color former storage unit 40 and the second color developer storage unit 44, the color formers 41 and 43 are not mixed. As the colorants 41 and 43 adsorb more water, the reach distance from the first color developer storage unit 40 and the second color developer storage unit 44 becomes longer. Although the moisture adsorption speeds of the first color changing portion 39 and the second color changing portion 42 may be equal, for example, the water adsorption speed of the second color changing portion 42 may be slowed by giving a difference between them.

測定の開始直後は、透明フィルム12の表示部16から第一変色部39の発色剤41が見える。そして、水分の吸着が進行すると、発色剤41は、第一変色部39の端部39aに達した時にとまり、それより先は、表示部16から第二変色部42の発色剤43が見えるようになる。これにより、発色剤41と発色剤43は色が異なるため、水分蒸発量が一定値を超えたことが確実にわかる。   Immediately after the start of measurement, the color former 41 of the first color changing portion 39 can be seen from the display portion 16 of the transparent film 12. As the moisture adsorption progresses, the color former 41 stops when it reaches the end 39a of the first color change portion 39, and beyond that, the color former 43 of the second color change portion 42 can be seen from the display portion 16. become. Thereby, since the color former 41 and the color former 43 are different in color, it is surely understood that the water evaporation amount exceeds a certain value.

この実施形態の水分蒸散量測定パッチ38は、上記実施形態と同様の効果を有するものであり、さらに、一定以上の水分蒸発量になると表示部16から見える色が異なる色に変化するため、水分蒸発量が一定値を超えたことが確実にわかり、測定しやすい。発色剤41と発色剤43は色が異なるため、水分蒸発量の度合いが確実に見やすくなり、正確に定量的に測定することができる。   The moisture transpiration amount measurement patch 38 of this embodiment has the same effect as that of the above embodiment, and furthermore, when the moisture evaporation amount exceeds a certain level, the color visible from the display unit 16 changes to a different color. Easily know that the amount of evaporation has exceeded a certain value, making it easy to measure. Since the color former 41 and the color former 43 are different in color, the degree of moisture evaporation is surely easy to see and can be measured accurately and quantitatively.

なお、本発明の水分蒸散量測定パッチは上記各実施の形態に限定されるものではなく、透明フィルムの印刷部の絵柄は自由に変更可能である。各部材の素材や形状も、適宜変更可能である。発色剤貯蔵部と変色部は別体でもよく、変色部の端部に発色剤貯蔵部が積層されてもよい。変色部の形状は、長方形の他、発色剤貯蔵部から遠い部位ほど細くなるような台形状にして、変色部先端側の吸着速度の低下を抑えるようにしても良い。発色剤貯蔵部及び変色部は、複数本並列に設けられていても良く、感度の異なるものや大きさの異なるものを複数設けても良い。水分蒸散量測定パッチの測定対象は、手の平以外に、顔、首、腕、手の甲、足等でもよい。人以外に動物の皮膚や植物の葉、果実の表皮、その他、工業的用途も含めて、微量の水分が蒸散する物質を対象に測定することができる。   In addition, the moisture transpiration amount measurement patch of the present invention is not limited to the above-described embodiments, and the pattern of the printing part of the transparent film can be freely changed. The material and shape of each member can be changed as appropriate. The color former storage part and the color change part may be separate from each other, and the color developer storage part may be laminated on the end of the color change part. The shape of the color changing portion may be a rectangular shape or a trapezoidal shape such that the portion farther from the color former storage portion becomes thinner to suppress a decrease in the adsorption speed on the tip side of the color changing portion. A plurality of color former storage portions and color change portions may be provided in parallel, or a plurality of different color sensitivities or sizes may be provided. In addition to the palm, the measurement target of the moisture transpiration amount measurement patch may be the face, neck, arm, back of the hand, foot, or the like. In addition to humans, it can be used to measure animal skin, plant leaves, fruit epidermis, and other substances that transpiration of trace amounts of water, including industrial applications.

10 水分蒸散量測定パッチ
12 透明フィルム
14 印刷部
16 表示部
18 目盛
22,32,50 粘着剤
24、39,42 変色部
26,40,44 発色剤貯蔵部
28,41,43 発色剤
29 溶解促進剤
30,46,48 水分不透過層
34,52 水分透過層
10 Moisture transpiration measurement patch 12 Transparent film 14 Printing unit 16 Display unit 18 Scale 22, 32, 50 Adhesive 24, 39, 42 Color changing unit 26, 40, 44 Color developing agent storage unit 28, 41, 43 Color developing agent 29 Dissolution promotion Agents 30, 46, 48 Moisture impermeable layer 34, 52 Moisture permeable layer

Claims (8)

粘着剤により測定対象表面に貼付される透明フィルムと、上記透明フィルムの粘着剤側の面に設けられ発色剤を吸着させた発色剤貯蔵部と、前記発色剤貯蔵部に連なり一方向に長く形成され前記発色剤の溶解液が長手方向に浸透する変色部と、前記変色部の前記透明フィルム側と反対側の面を覆う水分不透過層と、上記透明フィルムの粘着剤側の面に対面し前記発色剤貯蔵部を覆う水分透過層が設けられ、前記透明フィルムには前記変色部を視認可能にする透明な表示部と、前記表示部の周辺部に設けられ前記変色部の長手方向に沿う目盛が描かれた印刷部が設けられていることを特徴とする水分蒸散量測定パッチ。   A transparent film that is attached to the surface to be measured by an adhesive, a color former storage part that is provided on the adhesive side surface of the transparent film and adsorbs the color former, and is formed to be long in one direction connected to the color former storage part. And the color changing portion through which the solution of the color former permeates in the longitudinal direction, the moisture-impermeable layer covering the surface of the color changing portion opposite to the transparent film side, and the surface of the transparent film facing the adhesive side. A moisture permeable layer is provided to cover the color former storage part, and the transparent film is provided with a transparent display part that enables the color change part to be visually recognized, and is provided in a peripheral part of the display part along the longitudinal direction of the color change part. A moisture transpiration measuring patch, characterized in that a printing part with a scale is provided. 前記変色部は複数設けられ、前記変色部に各々前記発色剤貯蔵部が設けられ、複数の前記変色部は互いに重ねられて前記表示部に対面し、前記重ねられた複数の変色部は、相対的に前記表示部に近い側に位置した前記変色部が前記表示部に対して遠い側に位置した前記変色部より長手方向に短く形成され、前記各変色部同士の間には水分不透過層が設けられ、複数個の前記発色剤貯蔵部には、互いに異なる色の発色剤が吸着されている請求項1記載の水分蒸散量測定パッチ。   A plurality of the color changing portions are provided, and each of the color changing portions is provided with the color former storage portion. The plurality of the color changing portions are overlapped with each other to face the display portion. The discoloration portion located on the side closer to the display portion is formed shorter in the longitudinal direction than the discoloration portion located on the side far from the display portion, and a moisture-impermeable layer is formed between the discoloration portions. The moisture transpiration amount measuring patch according to claim 1, wherein the color formers of different colors are adsorbed to the plurality of color former reservoirs. 前記発色剤貯蔵部には、前記発色剤の溶解・浸透速度を早める溶解促進剤として親水性高分子材料を混合した請求項1又は2記載の水分蒸散量測定パッチ。   The moisture transpiration amount measurement patch according to claim 1 or 2, wherein a hydrophilic polymer material is mixed in the color former storage section as a dissolution accelerator for increasing the dissolution / penetration rate of the color former. 前記発色剤貯蔵部には、前記発色剤の溶解・浸透速度を速める界面活性剤を混合した請求項1又は2記載の水分蒸散量測定パッチ。   The moisture transpiration amount measuring patch according to claim 1 or 2, wherein a surfactant that accelerates the dissolution / penetration rate of the color former is mixed in the color former reservoir. 前記界面活性剤は、非イオン系界面活性剤である請求項4記載の水分蒸散量測定パッチ。   The moisture transpiration amount measuring patch according to claim 4, wherein the surfactant is a nonionic surfactant. 前記親水性高分子材料は、ポリエチレングリコールである請求項3記載の水分蒸散量測定パッチ。   The moisture transpiration amount measurement patch according to claim 3, wherein the hydrophilic polymer material is polyethylene glycol. 前記変色部と前記発色剤貯蔵部及び表示部は、各々複数設けられている請求項1乃至6のいずれかに記載の水分蒸散量測定パッチ。   The moisture transpiration amount measurement patch according to any one of claims 1 to 6, wherein a plurality of the discoloration section, the color former storage section, and the display section are provided. 前記変色部と前記発色剤貯蔵部は、同一のシート材により形成され、前記発色剤貯蔵部は固体の材料である請求項1乃至6のいずれかに記載の水分蒸散量測定パッチ。
The moisture transpiration amount measuring patch according to any one of claims 1 to 6, wherein the color changing portion and the color former storage portion are formed of the same sheet material, and the color former storage portion is a solid material.
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JP2017058156A (en) * 2015-09-14 2017-03-23 旭化成パックス株式会社 Inspection kit

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JP2017023408A (en) * 2015-07-22 2017-02-02 ライフケア技研株式会社 Perspiration amount measuring patch and perspiration amount measuring instrument
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