JP2007203244A - Crushing and agitating method - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a crushing and agitating method which enables the crushing and agitating of samples even by a battery power source. <P>SOLUTION: A permanent magnet 12 magnetized in a diameter direction is revolved around the outer periphery of a cylindrical container A housing a magnetized treating medium B and a material to be treated C while being rotated, and is reciprocally moved in a cylindrical axis direction. The treating medium B revolves while rotating in the cylindrical container A resulting in grinding or agitating the material to be treated C. Since the material to be treated C is thoroughly agitated and pressed by vertically reciprocal movement of the treating medium B, the material to be treated C is efficiently crushed by grinding and pressing. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to a crushing and agitation method for crushing or agitating a sample for inspection or analysis, and in particular, a place where a supply of commercial power cannot be obtained for crushing and agitation processes such as cell crushing, emulsification and homogenization of a biological sample. However, the present invention relates to a crushing and stirring method that can be carried out.

  For example, in order to use a biological sample for DNA analysis or the like, a pretreatment for crushing cells of animals or plants is required. As the crushing method, a crushing apparatus that performs crushing by ultrasonic waves, crushing by pressure, vibration crushing using a crushing medium such as beads is used. In addition, in the sample analysis work, pretreatment for stirring the sample is necessary to emulsify or homogenize the sample. A magnetic stirrer that magnetically rotates the stirrer placed in the container or a pestle inserted in the container by a motor. A stirring device such as a rotating homogenizer is used.

Since the crushing device is driven using commercial power as a power source, crushing treatment cannot be performed outdoors or in a thermostatic chamber where commercial power cannot be obtained. In addition, since the crushing device is a relatively large device, it is necessary to bring the material to be crushed into the place where the crushing device is installed and crush it. Between the place where the analysis is performed and the place where the pretreatment is performed This is an inefficient work that involves movement. In addition, even if cell disruption is required at the sample collection site, it is difficult to implement it. There is a need for a crushing apparatus that can carry out crushing processing manually or driven by a battery power source.

  As a conventional technology that enables manual crushing of a material to be crushed, the material to be crushed is frozen and put into a crushing vessel, and the crushing vessel into which the crushing weight is placed is manually vibrated, A container for crushing a frozen sample that crushes a frozen object to be crushed is known (see Patent Document 1).

  Further, a crushing method is known in which a pestle that is rotationally driven by a motor is inserted into a cylindrical container that contains a material to be crushed, and the material to be crushed is crushed while stirring (see Patent Document 2). In this crushing method, the motor can be driven by a battery power source.

In addition, a magnetic stirrer used for stirring a sample generally rotates a rod-shaped permanent magnet in a horizontal plane, places a stirring container above the rotating permanent magnet, and puts the stirring bar placed in the stirring container into a permanent magnet. It is rotated by the magnetic force from. Therefore, it is necessary to use a flat-bottomed container such as a beaker, and only one magnetic stirrer can stir one container, and the stirring ability is low, and the stirring process cannot be performed on the cylindrical container on the test tube. There is. In order to solve this problem, a magnetic stirrer capable of simultaneously stirring a plurality of cylindrical containers is known (see Patent Document 3).
Utility Model Registration No. 3086539 JP 2000-333669 A Japanese Patent Laid-Open No. 2000-04393

  However, the frozen sample crushing container in the above-mentioned prior art is based on the premise that the crushing material is easily crushed because the compressive force applied to the crushing material is small. Equipment is required, and although it can be manually crushed, it is difficult to use outdoors. In addition, there is a problem that requires a large amount of labor for crushing.

  In addition, the crushing method using a pestle in the above-mentioned prior art is suitable for stirring for sample emulsification and homogenization, but because of its small crushing capacity, it is suitable for cells such as fibrous samples and hard samples. When crushing or the like, it is necessary to use a crushing medium such as beads together. In addition, in order to avoid contamination, it is necessary to replace the pestle every time processing is performed on one cylindrical container, and the work of attaching and detaching the pestle from the rotation drive shaft of the motor is troublesome, and there is a problem of lack of workability. .

  Moreover, although the magnetic stirrer in the said prior art can be said to be suitable for stirring the liquid sample accommodated in the cylindrical container, it cannot be applied to a crushing process. That is, in the magnetic stirrer, the stirrer only rotates at a fixed height in the container. Therefore, although the grinding effect necessary for the crushing process can be obtained, an important crushing effect is expected in the crushing process. I can't.

  An object of the present invention is to provide a crushing and stirring method capable of exhibiting an effective crushing ability even outdoors where a large driving power cannot be obtained.

The crushing and stirring method according to the first invention of the present application for achieving the above object includes an operation of rotating the permanent magnet around the outer periphery of the cylindrical container and an operation of changing the relative position of the permanent magnet and the cylindrical axis direction of the cylindrical container. The magnetized body accommodated in the cylindrical container is rotated and moved up and down to crush or stir the object to be processed accommodated in the cylindrical container.

According to the above crushing and stirring method, the magnetized body accommodated in the cylindrical container is rotated following the rotation of the permanent magnet by the operation of rotating the permanent magnet around the outer periphery of the cylindrical container, so that it is accommodated in the cylindrical container. The workpiece is ground or stirred. Further, by changing the relative position between the permanent magnet and the cylindrical axis direction of the cylindrical container, the magnetized body moves in the cylindrical axis direction within the cylindrical container, so that the workpiece is evenly stirred, and the magnetized body is moved to the cylindrical container. The workpiece is crushed by the compressive force that collides with the inner bottom surface.

  Further, in the crushing and stirring method according to the second invention of the present application, the permanent magnet is rotated around the outer periphery of the cylindrical container while reversing the magnetic pole, thereby rotating and revolving the magnetized body accommodated in the cylindrical container. The processing object accommodated in the container is crushed or stirred.

  According to the above crushing and stirring method, the magnetized body can be revolved while rotating in the cylindrical container, so that the workpieces accommodated in the cylindrical container are uniformly stirred by the various movements of the magnetized body, The workpiece is effectively ground between the magnetic body and the inner peripheral surface of the cylindrical container.

  In the crushing and stirring method according to the third invention of the present application, the permanent magnet is rotated around the outer periphery of the cylindrical container while reversing the magnetic poles, and the relative height position between the permanent magnet and the cylindrical container is changed. The object to be processed contained in the cylindrical container is crushed or agitated by rotating the revolving motion, revolving motion and reciprocating motion in the cylindrical axis direction of the magnetized body accommodated.

  According to the crushing and stirring method described above, the magnetized body can be revolved while rotating in the cylindrical container and can be reciprocated in the cylindrical axis direction, so that the object to be stored in the cylindrical container can be moved by various movements of the magnetized body. The object to be treated is uniformly stirred, the object to be treated is effectively ground between the magnetized body and the inner peripheral surface of the cylindrical container, and the object to be treated is crushed by the reciprocating motion of the magnetized body.

Moreover, the crushing and stirring method according to the fourth invention of the present application separately shields the magnetism from the plurality of permanent magnets by the magnetic shield rotating between the plurality of permanent magnets arranged around the outer periphery of the cylindrical container and the cylindrical container. By passing through, the magnetized body accommodated in the cylindrical container is caused to rotate and revolve, thereby crushing or stirring the object to be processed accommodated in the cylindrical container.

According to the crushing and stirring method, when the magnetic field from an arbitrary number of permanent magnets arranged around the outer periphery of the cylindrical container is blocked by the magnetic shield, the magnetized body moves to a position where the magnetic transmission is present, Magnetic adsorption and magnetic repulsion occur at the magnetically transmitted position, and the magnetized body is repeatedly rotated, revolved, or linearly moved, and the object to be processed is stirred or ground by the magnetized body.

Moreover, the crushing and stirring method according to the fifth invention of the present application separately shields the magnetism from the plurality of permanent magnets by the magnetic shield that rotates between the plurality of permanent magnets arranged around the outer periphery of the cylindrical container and the cylindrical container. The object to be treated is accommodated in the cylindrical container by rotating and reciprocating the magnetized body accommodated in the cylindrical container and reciprocating in the cylindrical axis direction by changing the magnetic transmission position with respect to the height direction of the cylindrical container. It is characterized by crushing or stirring an object.

According to the above crushing and stirring method, when the magnetism of the plurality of permanent magnets is shielded or transmitted by the magnetic shield, the magnetized body moves to the position where it is magnetically transmitted. When the magnet is rotated and magnetically transmitted in the height direction of the cylindrical container, the magnetized body moves up and down. Therefore, when the magnetic transmission and magnetic shielding of a plurality of permanent magnets are changed, the magnetized body can be moved in the three-dimensional direction, and the workpiece is stirred, ground, or crushed by the three-dimensional movement of the magnetized body. The

In each of the above configurations, the magnetic body can be dropped from the upper limit position toward the inner bottom surface of the cylindrical container by magnetically blocking at the upper limit position where the permanent magnet is moved upward, and the workpiece to be processed by the dropped magnet body. Can be crushed. Furthermore, the effect of the crushing can be improved by magnetically blocking at the upper limit position where the permanent magnet is moved upward and simultaneously applying an attractive magnetic field downward to attract the falling magnetized body to the inner bottom surface of the cylindrical container.

In addition, the magnetized body is a columnar shape having a diameter smaller than the inner diameter of the cylindrical container, and its lower end shape is preferably formed in a shape corresponding to the inner bottom surface shape of the cylindrical container, and by rotating, moving or dropping in the cylindrical container The effects of stirring, grinding and crushing can be improved.

Further, the surface of the magnetized body is preferably coated with resin or ceramic, and not only can the metal component be prevented from being mixed into the object to be treated, but also the resistance to the object to be treated and buffer solution can be improved. it can.

In addition, by forming the magnetized body in a cold storage structure, it is possible to suppress the temperature rise of the workpiece due to frictional heat or the like by the magnetized cold storage in advance, and to treat the workpiece that is likely to be altered by the temperature rise. Is preferred.

Further, a permanent magnet is placed outside the lid that closes the opening of the cylindrical container, and the magnetized body moved upward is magnetically attracted to the inside of the lid, and the magnetized body is removed while the lid is removed from the cylindrical container. If it is made to take out from a cylindrical container, it will become possible to take out without touching a hand and an instrument to a magnetized body which becomes an obstacle after processing.

  According to the present invention, since the magnetized body can be rotated not only in the cylindrical container containing the object to be processed but also moved in a complicated manner such as a vertical movement, the object to be processed is effectively stirred and crushed by the magnetized body. Is done. When the workpiece is agitated, it can be evenly agitated by rotating or vertically moving the magnetized body. In addition, when crushing the workpiece, the crushing action of the magnetized body colliding with the bottom surface of the cylindrical container is performed in addition to the crushing by rotation of the magnetized body. be able to. Furthermore, since it can be driven by a battery power source or manually, a crushing and agitating device that can be used at a site where a workpiece is collected or where commercial power cannot be obtained is obtained.

Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings. The present embodiment is an example embodying the present invention, and does not limit the technical scope of the present invention.
FIG. 1 shows the configuration of a crushing and agitating apparatus 1 according to a first embodiment that embodies the crushing and agitating method according to the present invention, which is a basic configuration of the present invention. Using the motor 7 as a drive source, the permanent magnet 6 is rotated around the outer periphery of a bottomed cylindrical cylindrical container A containing a processing medium (magnetized body) B by a rotational driving mechanism 8, and the cylindrical container is driven by a vertical driving mechanism 9. The permanent magnet 6 is moved up and down in the direction of the cylindrical axis A. Due to the rotation and vertical movement of the permanent magnet 6, the processing medium B, which is formed by magnetizing the ferromagnetic material in a cylindrical shape, rotates and moves up and down in the cylindrical container A. Object C is crushed or stirred.

When the processing object C is crushed, the processing object C is ground between the processing medium B and the cylindrical container A by the rotational movement of the processing medium B, and the processing medium B moves up and down to move the bottom of the cylindrical container A. The workpiece C is crushed by colliding with. The vertical movement of the processing medium B can be applied evenly even to a long object C such as a leaf of a plant, and the processing medium B moved upward can be moved downward rapidly. The effect of crushing by the treatment medium B colliding with the bottom of the cylindrical container A is improved.

In addition, when the processing object C is stirred, the processing medium B rotates and moves up and down in the cylindrical container A so that the processing object C accommodated in the cylindrical container A is evenly stirred, and emulsified or homogenized. Etc. can be performed efficiently. When the main purpose is stirring, the processing medium B can be improved in the stirring effect by providing a projection provided later.

In the above configuration, the rotation drive mechanism 8 includes a reduction device that reduces the rotation speed of the motor 7 to a rotation speed suitable for crushing or stirring, and rotationally drives the permanent magnet 6. The vertical drive mechanism 9 reciprocates up and down the permanent magnet 6 that is rotated by a crank mechanism, a cam mechanism, or the like.

When the permanent magnet 6 is moved up and down, the processing medium B simply moves up and down following the permanent magnet 6, so that the processing medium B collides with the inner bottom surface of the cylindrical container A and crushes the workpiece C. Is small. Therefore, as shown in FIG. 2, it is effective to arrange a magnetic shield 11 in a ring shape at the upper limit position of the permanent magnet 6 so as to block the magnetic force exerted on the processing medium B by the permanent magnet 6 that has moved upward. It becomes a means. When the attractive force is interrupted by the magnetic shield 11 at the upper limit position of the processing medium B attracted by the permanent magnet 6 and lifted, the processing medium B falls by its own weight and collides with the inner bottom surface of the cylindrical container A. Since the workpiece C existing there is compressed, the workpiece C is crushed.

Further, in order to increase the crushing effect by the processing medium B, as shown in FIG. 2, the processing medium B is arranged on the suction magnet 14 provided on the bottom side of the cylindrical container A in synchronization with the arrival of the processing medium B at the upper limit position. A configuration in which the attracted magnetic shield 13 is moved away from the attracting magnet 14 is effective. Since the attracting force of the attraction magnet 14 acts on the processing medium B that falls, the fall acceleration of the processing medium B increases, and the target object C on the inner bottom surface of the cylindrical container A collides violently and is crushed.

In the above configuration, the rotationally driven permanent magnet 6 is driven up and down. However, the same effect can be obtained by rotating the permanent magnet 6 at a certain height position and moving the cylindrical container A up and down. In this case, the cylinder housing the cylindrical container A is moved up and down by the vertical drive mechanism 9.

In the above configuration, since the processing medium B rotates at a substantially constant position, the processing medium B is preferably formed to have a diameter slightly smaller than the inner diameter of the cylindrical container A. Can be ground extensively.

Further, the permanent magnet 6 does not necessarily have to be configured as a magnet block in which the N pole and the S pole are arranged to face each other, and one permanent magnet 6 with one of the N pole and the S pole facing the cylindrical container A side is rotated. It can also be driven. In this case, it is desirable to use the processing medium B formed to have a diameter that is approximately ½ of the inner diameter of the cylindrical container A, and since the rotating state revolves along the inner peripheral surface of the cylindrical container A, A state similar to crushing by rotating a pestle in a mortar like a circle is obtained.

In the above-described configuration, the processing medium B merely rotates and moves up and down following the rotation of the permanent magnet 6, so that the processing medium B is large enough to crush a hard sample even if it is suitable for use in stirring a liquid sample. It cannot be expected to obtain a crushing action. In order to obtain a larger crushing effect, it is necessary to increase the behavior change of the processing medium B. Next, an embodiment in which the behavior change of the processing medium B is increased will be described.

3 and 4 show the configuration of the crushing and agitating apparatus 2 according to the second embodiment. The permanent magnet 12 formed in a columnar shape is magnetized so that there are N and S poles in the diameter direction. As shown in FIG. 4, the N and S poles of the permanent magnet 12 are reversed. In this way, it is driven to rotate so as to perform a revolving motion that rotates on the circumference of a predetermined radius while rotating.

In FIG. 4, when the permanent magnet 12 is rotated, the positions of the north and south poles facing the cylindrical container A are reversed. When the magnetic poles are reversed by the rotation of the permanent magnet 12, the magnetic repulsive force and the magnetic attraction force act on the magnetized processing medium B to generate a rotation that rotates at substantially the same position. When the revolving motion rotating around the outer periphery of the cylindrical container A is performed while rotating the permanent magnet 12, the processing medium B revolves along the inner periphery of the cylindrical container A while following the revolving motion of the permanent magnet 12. Exercise. By appropriately setting the diameter of the processing medium B with respect to the inner diameter of the cylindrical container A, the workpiece C existing on the bottom surface of the cylindrical container A can be evenly ground.

A known planetary gear structure or the like can be applied to the structure in which the permanent magnet 12 revolves while rotating. In the planetary gear structure, the permanent magnet 12 can be rotated and revolved by attaching the permanent magnet 12 to the rotating shaft of the planetary gear that revolves while revolving around the sun gear. In the present embodiment, the permanent magnet 12 causes the permanent magnet 12 to rotate and revolve as shown in FIG. 3 in order to move up and down in the direction of the cylindrical axis of the cylindrical container A in addition to the rotation and revolution. The self-revolution mechanism 15 is rotationally driven by the rotational drive mechanism 16, and the rotational drive mechanism 16 is moved up and down in the height direction of the cylindrical container A by the elevation drive mechanism 24.

In FIG. 3, the self-revolving mechanism 15 abuts the rollers 12 a fixed to the top and bottom of the permanent magnet 12 against the outer peripheral surface of the container housing cylinder 21 provided in the housing 20, and supports rollers 29 and 29 (see FIG. 4). ) Is rotatably contacted with the outer peripheral surface of the container housing cylinder 21, and rotates around the outer periphery of the container housing cylinder 21 and moves up and down. The rotating shaft of the permanent magnet 12 and the rotating shaft of the support roller 29 are supported by the rotating support 17. In this self-revolving mechanism 15, the upper and lower surfaces of the rotation support 17 are held by the rotation drive mechanism 16 via bearings 22. The rotational drive mechanism 16 rotationally drives the rotational drive wheel 25 through a speed reduction mechanism by a motor (not shown), and rotationally drives the self-revolving mechanism 15 by the rotational drive wheel 25.

The revolving mechanism 15 moves up and down along the container housing cylinder 21 by moving the rotational drive mechanism 16 linearly up and down by the up and down drive mechanism 24. The elevating drive mechanism 24 is operated by an elevating drive source 26 equipped with a motor and a speed reduction mechanism, and reciprocates the rotary drive mechanism 16 up and down along the elevating shaft 27. The elevating drive mechanism 24 can be configured by a crank structure, a ball screw structure, or the like.

In the above configuration, when the cylindrical container A containing the processing medium B and the workpiece C is inserted into the container containing cylinder 21 and the rotation driving mechanism 16 is activated, the rotation support wheel 17 is driven to rotate by the rotation driving wheel 25. The permanent magnet 12 is rotated around the outer periphery of the container housing cylinder 21. Since the permanent magnet 12 is in contact with the container housing cylinder 21 by the upper and lower rollers 12a, the rotation of the rotating support 17 causes a revolving motion while rotating around the outer periphery of the cylindrical container A. As described above, the cylindrical container A The processing medium B accommodated therein is rotated and revolved, and the workpiece C is ground or stirred. Since the workpiece C is at the bottom of the cylindrical container A, the revolving mechanism 15 is mainly at the lowest position of the up-and-down movement so that the processing medium B mainly rotates and revolves on the bottom side of the cylindrical container A. Is driven to rotate.

The elevating drive mechanism 24 is activated at a required timing to move the rotary drive mechanism 16 up and down. When the elevating drive mechanism 24 is activated, the rotational drive mechanism 16 is moved upward and the self-revolving mechanism 15 is moved up and down along the container housing cylinder 21. The raising / lowering drive mechanism 14 raises the rotation drive mechanism 16 to the upper limit position shown with a broken line, and then shifts to a lowering operation. Since the processing medium B also moves up and down while rotating and revolving in the cylindrical container A by the up-and-down movement of the self-revolving mechanism 15, the processing object C is stirred up and down, and the processing medium B is compressed by the action of the processing medium B compressing. Crushed.

In order to improve the effect of crushing the workpiece C, it is desirable that the ascending movement speed of the self-revolving mechanism 15 is slow and the descending movement speed is high. For the change in the speed of the up-and-down movement, when the up-and-down drive mechanism 24 is configured by a crank structure, it is preferable to apply a crank structure provided with a known quick return mechanism. In the case of the ball screw structure, this can be realized by switching the rotational drive direction and simultaneously increasing the rotational speed.

In order to increase the falling speed of the raised processing medium B, it is effective to dispose an upper magnetic shield 30 on the upper peripheral surface of the container housing cylinder 21 as shown in FIG. Since the magnetic field from the permanent magnet 12 of the self-revolving mechanism 15 moved upward is shielded by the upper magnetic shield 30, the processing medium B from which the magnetic attractive force by the permanent magnet 12 has been released falls by its own weight, and the cylindrical container A Therefore, the effect of crushing the workpiece C increases.

Further, an attraction magnet 28 is disposed at a position corresponding to the bottom surface of the container housing cylinder 21, and the lower magnetic shield 31 is put in and out between the attraction magnet 28 and the bottom surface of the container housing cylinder 21. The operation of moving the lower magnetic shield 31 in and out is synchronized with the vertical movement of the rotation drive mechanism 16, and the lower magnetic shield 31 from above the attracting magnet 28 at the timing when the self-revolving mechanism 15 reaches the position where the upper magnetic shield 30 is disposed. Is moved to the retracted position. When the lower magnetic shield 31 moves from above the attracting magnet 28, the magnetic attraction force of the attracting magnet 28 reaches the falling processing medium B, so that the fall acceleration of the processing medium B increases, and the object to be processed with a large compression pressure. Since it collides with C, the effect | action which crushes to-be-processed object C increases.

In the configuration described above, the magnetization direction of the processing medium B is the diameter direction, but it can also be magnetized in the height direction. When the processing medium B is magnetized in the vertical direction, when the permanent magnet 12 is revolved around the outer periphery of the cylindrical container A while rotating, the processing medium B swings and moves in the cylindrical container as shown in FIG. Revolve in A. The workpiece C at the bottom of the cylindrical container A can be ground by this swinging motion and revolving motion.

Further, as shown in FIG. 5 (b), when the pair of permanent magnets 32a and 32b magnetized in the diametrical direction is revolved around the outer periphery of the cylindrical container A while rotating the combined permanent magnet 32, the processing is performed. The medium B revolves while rotating in the cylindrical container A as in the case shown in FIG. The workpiece C at the bottom of the cylindrical container A can be ground by the rotation and revolution.

When the processing medium B is magnetized in the vertical direction, as shown in FIG. 5, if the permanent magnet 34 is disposed on the bottom side of the cylindrical container A, a magnetic attractive force or a magnetic repulsive force acts on the lower magnetic pole of the processing medium B. Can be made. When the magnetic pole direction of the permanent magnet 34 is set so that the magnetic attractive force acts, the effect of crushing the workpiece C by attracting the processing medium B moved to the raised position to the bottom of the cylindrical container A is obtained. . Conversely, if the magnetic pole direction of the permanent magnet 34 is set so that the magnetic repulsive force acts, the processing medium B can be easily moved upward. Further, by repeating the operation of reversing the magnetic poles of the permanent magnet 34, the processing medium B can move up and down, and the effect of crushing the object C to be processed can be improved. This wobbling motion can also be obtained by changing the distance from the bottom of the cylindrical container A of the permanent magnet 34 in which magnetic poles are arranged in the direction of magnetic repulsion to the processing medium B.

The configuration in which the processing medium B rotates and revolves in the cylindrical container A is not limited to the structure in which the permanent magnet 12 is rotated and revolved as in the above-described configuration, but can also be in the following structure in which the permanent magnet 12 is fixed. is there.

FIG. 6 illustrates a rotation driving method of the processing medium B in the crushing and agitating apparatus according to the third embodiment. A plurality (eight in this case) of permanent magnets 33a to 33h are provided around the outer periphery of the cylindrical container A as magnetic poles. The rotating magnetic shield 35 provided with the magnetic transmission window 35a is rotated between the plurality of permanent magnets 33a to 33h and the cylindrical container A so as to be reversed between adjacent directions.

As shown in the figure, the processing medium B contacts the inner peripheral surface of the cylindrical container A with the magnetic pole (S pole) attracted to the magnetic pole (N pole in the illustrated state) of the permanent magnet 33a facing through the magnetic transmission window 35a. When the rotating magnetic shield 35 rotates and the magnetic transmission window 35a moves to the position of the adjacent permanent magnet 33b, since the magnetic pole facing the cylindrical container A side of the permanent magnet 33b is the S pole, the processing medium B rotates due to magnetic repulsion. The magnet is magnetically attracted to the permanent magnet 33b on the N pole side and comes into contact with the inner peripheral surface of the cylindrical container A.

As the rotating magnetic shield 35 rotates, the processing medium B revolves along the inner peripheral surface of the cylindrical container A while rotating, so that the workpiece C accommodated in the cylindrical container A is stirred or To be ground. The magnetic transmission window 35a provided in the rotating magnetic shield 35 can be provided at a plurality of locations instead of at one location. For example, when the permanent magnets 33a to 33h are arranged as shown in the figure, if the magnetic transmission window 35a is also provided at a position facing the diametrical direction of the rotating magnetic shield 35, the processing medium B is magnetized on one side. Since the action of adsorption and magnetic repulsion is exerted on the other side, the movement of the processing medium B to revolve is increased, and the effect of stirring or grinding the workpiece C can be improved.

In the structure in which the processing medium B is rotated and revolved using the rotating magnetic shield 35, to move the processing medium B up and down in the cylindrical container A, the rotating magnetic shield 35 is cylindrical as shown in FIG. It can be realized by forming a shape and moving the plurality of permanent magnets 33 up and down. Since the magnetic transmission window 35a is not opened at a portion corresponding to the upper side of the cylindrical container A, when the permanent magnet 33 moves above the cylindrical container A, the magnetic attractive force to the processing medium B is cut off and the processing medium B falls. Thus, the action of crushing the workpiece C is obtained. Similar to the configuration described above, the lower magnetic shield 31 on the attracting magnet 28 arranged at the position corresponding to the bottom of the cylindrical container A is moved to the retracted position in synchronization with the permanent magnet 33 reaching the rising limit position. Then, a magnetic attraction force is exerted on the falling processing medium B, and the falling acceleration can be increased.

FIG. 8 shows a main configuration of the crushing and agitating device 4 according to the fourth embodiment, and surrounds the cylindrical container A with a plurality of permanent magnets 33 formed in a vertically long shape corresponding to the height dimension of the cylindrical container A. A rotating magnetic shield 35 provided with a magnetic transmission window 35a that is fixed on the circumference and opens to a height corresponding to the height of the processing medium B is moved up and down.

When the rotating magnetic shield 35 is moved up and moved from the position shown in the figure while rotating the rotating magnetic shield 35 to rotate and revolve the processing medium B in the cylindrical container A, the position of the magnetic transmission window 35a is increased. Along with this, the processing medium B also moves up in the cylindrical container A. If the attracting magnet 28 is provided on the inner bottom portion of the rotating magnetic shield 35 formed in the bottomed cylindrical shape, a strong attracting magnetic field is applied to the bottom portion of the cylindrical container A when the processing medium B moves to a predetermined ascending position. . When the processing medium B reaches a predetermined rising position, the magnetic transmission window 35a is magnetically shielded, the rotary magnetic shield 35 is further moved upward, and the rotational speed of the rotary magnetic shield 35 is rapidly increased. When the magnetic attraction of the medium B is shaken off, the processing medium B falls and is attracted to the attracting magnet 28 and collides with the bottom side of the cylindrical container A, so that the effect of crushing the workpiece C is improved.

The shape, opening diameter, and position of the magnetic transmission window 35a provided in the rotating magnetic shield 35 can be arbitrarily set. For example, as shown in FIG. 9, when the plurality of magnetic transmission windows 35a are formed in a spiral shape, the processing medium B is reciprocated up and down while rotating the processing medium B only by rotating the rotary magnetic shield 35 without moving up and down. be able to.

Further, when the rotating magnetic shield 35 is rotated while being reciprocally oscillated small up and down, the processing medium generates vertical vibrations in addition to the rotation and revolution movements, so that the effect of crushing the workpiece C can be improved. .

In each of the first to fourth embodiments described above, the permanent magnets 12 and 33 or the magnetic shield 35 are driven up and down, but the processing medium B is also moved into the cylindrical container by moving the cylindrical container A up and down. It can be moved up and down within the meaning A.

In addition, the cylindrical container A is basically placed in the vertical direction, but the cylindrical container A can be placed horizontally if the cylindrical container A can be sealed with a lid D that closes the opening of the cylindrical container A so that the cylindrical container A does not leak. It is also possible to place and crush or stir. In this case, by reducing the length of the processing medium B or by providing protrusions on the peripheral surface, it is possible to suppress a reduction in the action of grinding and stirring in the horizontal placement.

In each configuration described above, the processing medium B has a columnar shape and the lower part has a shape corresponding to the shape of the inner bottom surface of the cylindrical container A. However, the shape is not limited to this shape, and as shown in FIG. Further, it can be configured in a shape in which a plurality of protrusions 37 are provided in the diameter direction. With this configuration, not only the stirring ability of the workpiece C is improved, but also the action of shearing the fibrous workpiece C is increased, and the grinding effect can be improved. Further, the treatment medium B is not only magnetized so that there are counter electrodes on both sides in the diametrical direction, but may also be magnetized in each of the plurality of protrusions 37 as shown in FIG. it can. As described above, the magnetization direction is not limited to the diameter direction, and the motion of the processing medium B can be changed by magnetizing in the vertical direction.

Moreover, there is a concern that the processing medium B formed of metal is mixed in the processing object C in which the metal powder peeled off with the crushing is crushed. When mixing of metal is not preferable, it is preferable to coat the surface of the processing medium B with ceramic or fluororesin, and there is an advantage that resistance when a corrosive buffer solution is used can be improved. can get.

Since the cylindrical container A can be a general-purpose tube called a centrifuge tube or a sample tube, the lower end shape of the processing medium B corresponds to the inner bottom surface shape of the cylindrical container A as shown in FIG. By using one, the effect of grinding or crushing the workpiece C can be improved.

Further, if the agitation process is performed with priority, as shown in FIG. 12, the processing medium B can be configured in a shape suitable for agitation. The processing medium B3 shown in FIG. 12A has a plurality of stirring protrusions 62 formed below a main body 61 formed of a magnetized ferromagnetic material. Further, a processing medium B4 shown in FIG. 12B has a main body core 63 formed by a ferromagnetic material magnetized on the upper part where a plurality of stirring blades 64 protrude downward by resin molding. The stirring blades 64 can be bent inward according to the shape of the bottom of the cylindrical container A, so that the workpiece C can be uniformly stirred by moving up and down in the cylindrical container A.

In addition, the processing medium B5 shown in FIG. 12C allows a rotating main body 67 formed of a magnetized ferromagnetic material to be freely rotated in a resin outer cylinder 65 in which a plurality of slits 66 are formed below. Arranged. Since a plurality of stirring protrusions 68 are provided below the rotary body 67 at positions corresponding to the slits 66, when the rotary body 67 is driven to rotate, the liquid or soft workpiece C is stirred by the stirring protrusions 68. At the same time as being dispersed, it is ejected outward from the slit 66 and stirred or crushed.

These processing media B3 to B5 are compared to those in which a rod-shaped pestle that has been widely used in the past is inserted into a cylindrical container containing the object to be processed, and the object is homogenized by rotating the pestle with a motor. In addition, since the processing media B3 to B5 can be rotated even in a state where the cylindrical container A is sealed, the processing object C is not scattered to the outside, and is suitable when the processing object C is a harmful substance. It becomes a proper stirring and crushing means.

When the crushing process is performed, heat is generated in the cylindrical container A due to friction. Since heat generation of the cylindrical container A and the processing medium B is not preferable when the object to be processed C is easily deteriorated due to a temperature increase, it is necessary to suppress the temperature increase of the object C to be processed.

As shown in FIG. 13, it is effective to form the processing medium B2 in a hollow structure and enclose a cold storage material 38 in the hollow. When this processing medium B2 is cooled in advance by a cooling device and the cold storage material 38 cooled or frozen is put into the cylindrical container A and crushed, the workpiece C is cooled by the processing medium B2 in direct contact therewith. Further, the quality change of the workpiece C due to the temperature rise can be effectively prevented.

In the configuration described above, the processing medium B present in the cylindrical container A after the crushing or stirring process becomes an obstacle in the subsequent work, and therefore it is preferable that the processing medium B can be easily removed from the cylindrical container A. It is. As shown in FIG. 14, when the permanent magnet 40 is placed outside the lid D of the cylindrical container A after the processing is completed, the processing medium B is pulled up above the cylindrical container A, and then the magnetism of the permanent magnet 33 is shielded. The medium B is attracted by the permanent magnet 40 and attracted to the inside of the lid D. When the processing medium B is attracted, the permanent magnet 40 becomes difficult to move on the lid D. Therefore, the permanent magnet 40 does not come off during the operation of removing the lid D from the cylindrical container A. When the lid D is removed from the cylindrical container A, the lid D At the same time, the processing medium B is taken out of the cylindrical container A.

In the embodiment described above, the processing medium B is rotated and moved up and down. However, when the processing can be performed only by rotating on the bottom side of the cylindrical container A, the vertical movement can be omitted. .

As described above, according to the present invention, the workpiece can be crushed or agitated by moving the magnetized body accommodated in the cylindrical container in a three-dimensional direction including rotational motion using a permanent magnet. The crushing process and the stirring process can be performed by a power source or manually. Therefore, the crushing and stirring process can be performed outdoors or in a safety cabinet where the required power cannot be obtained, and the sample can be processed at the site where analysis or inspection is performed.

The principal part sectional drawing which shows the structure of the crushing and stirring apparatus which concerns on 1st Embodiment. Sectional drawing which shows the structure which improves the crushing effect by a processing medium. Sectional drawing which shows the structure of the crushing and stirring apparatus which concerns on 2nd Embodiment. Explanatory drawing explaining the movement of the processing medium in an apparatus same as the above. Sectional drawing which shows a structure when the magnetization direction of a processing medium is made into the up-down direction. The top view which shows the principal part structure of the crushing and stirring apparatus which concerns on 3rd Embodiment. The perspective view which shows the structure of the rotating magnetic shielding body in an apparatus same as the above. Sectional drawing which shows the principal part structure of the crushing and stirring apparatus which concerns on 4th Embodiment. The perspective view which shows the example of a setting of the magnetic transmission window in a rotary magnetic shielding body. The top view which shows the modification of a processing medium. Sectional drawing explaining the correspondence of a shape with a cylindrical container and a processing medium. The 1/2 cross section showing the example of composition of the processing medium suitable for stirring processing. Sectional drawing which shows the processing medium which provided the cool storage structure. Sectional drawing explaining the taking-out method from the cylindrical container of a processing medium.

Explanation of symbols

A Cylindrical container B, B2, B3, B4, B5 Processing medium C Processed object 1, 2, 3, 4 Crushing and stirring device 6, 12, 33, 34, 40 Permanent magnet 8, 16 Rotation drive mechanism 9, 24 Lifting drive Mechanism 11 Magnetic shield 13 Suction magnetic shield 14, 28 Suction magnet 15 Self-revolving mechanism 21 Container housing cylinder 30 Upper magnetic shield 31 Lower magnetic shield 32 Paired permanent magnet 35 Rotating magnetic shield 35a Magnetic transmission window

Claims (13)

The permanent magnet is rotated around the outer circumference of the cylindrical container, and the relative height position of the permanent magnet in the cylindrical axial direction of the cylindrical container is changed, whereby the magnetized body accommodated in the cylindrical container is rotated and moved up and down to form a cylinder. A crushing and stirring method, characterized by crushing or stirring a material to be treated contained in a container. The permanent magnet is rotated around the outer periphery of the cylindrical container while reversing the magnetic pole, thereby rotating or revolving the magnetized body accommodated in the cylindrical container to crush or agitate the object to be treated accommodated in the cylindrical container. Characterized crushing and stirring method. By rotating the permanent magnet around the outer periphery of the cylindrical container while reversing the magnetic pole and changing the relative height position of the permanent magnet and the cylindrical container, the magnetized body contained in the cylindrical container rotates, revolves and moves up and down. A crushing and stirring method, characterized by crushing or stirring a workpiece to be treated and accommodated in a cylindrical container. A magnetic shield rotating between a plurality of permanent magnets arranged around the outer periphery of the cylindrical container and the cylindrical container individually shields or transmits the magnetism from the plurality of permanent magnets, and rotates the magnetized body accommodated in the cylindrical container. A crushing and stirring method, characterized by crushing or stirring a workpiece to be processed and revolved and accommodated in a cylindrical container. A magnetic shield that rotates between a plurality of permanent magnets arranged around the outer periphery of the cylindrical container and the cylindrical container individually shields or transmits magnetism from the plurality of permanent magnets and applies a magnetic application position in the height direction of the cylindrical container. A crushing and stirring method characterized by crushing or stirring an object to be processed accommodated in a cylindrical container by rotating and revolving and moving up and down the magnetized body accommodated in the cylindrical container. The crushing and stirring method according to any one of claims 1, 3, and 5, wherein the magnetized body is dropped from the upper limit position toward the inner bottom surface of the cylindrical container by magnetically blocking at the upper limit position where the permanent magnet is moved upward. The crushing according to any one of claims 1, 3 and 5, wherein the permanent magnet is magnetically cut off at an upper limit position and at the same time an attractive magnetic field is applied downward to attract the falling magnetized body to the inner bottom surface of the cylindrical container. Stirring method. The crushing and stirring method according to any one of claims 1 to 7, wherein the magnetized body magnetized in the vertical direction is vibrated up and down by reversing the magnetic poles of the permanent magnet disposed on the bottom of the cylindrical container or changing the facing distance. The crushing and stirring method according to any one of claims 1 to 8, wherein the magnetized body is moved up by magnetic repulsion. The crushing and stirring method according to any one of claims 1 to 9, wherein the magnetized body is formed in a columnar shape having a diameter smaller than the inner diameter of the cylindrical container, and a lower end shape thereof corresponds to an inner bottom surface shape of the cylindrical container. The crushing and stirring method according to any one of claims 1 to 10, wherein the surface of the magnetized body is coated with a resin or ceramic. The crushing and stirring method according to any one of claims 1 to 11, wherein the magnetized body is formed in a cold storage structure. A permanent magnet is placed outside the lid that closes the opening of the cylindrical container, the magnetized body moved upward is magnetically attracted to the inside of the lid, and the magnetized body is removed from the cylindrical container along with the removal of the lid from the cylindrical container. The crushing stirring method as described in any one of Claims 1-12 taken out outside.