JP2006252099A - Bio-security system - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To realize an advanced safer bio-security system against a pathogen such as a bacterium and virus, which causes an infectious disease. <P>SOLUTION: The bio-security system 1, which performs security management of the pathogen causing an infectious disease, comprises an IC tag 11 mounted on a pathogen container 10 which stores pathogenic bacteria and memorizes management information per a unit of a pathogen container, a plurality of terminals 2, 4, and 5 for receiving and transmitting management information between the IC tag 11, and a server 3 connected with the plurality of terminals 2, 4, and 5 via a communication line. The bio-security system 1 integrally performs history management of the pathogen per a unit of a pathogen container by the server 3 on the basis of receiving and transmitting of the management information between the plurality of terminals 2, 4, and 5 and IC tag 11. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a biosecurity system, and is particularly suitable for a biosecurity system that individually manages pathogens such as bacteria and viruses that cause infectious diseases.

  As a conventional nosocomial infection diagnosis apparatus, there is one disclosed in Japanese Patent Laid-Open No. 7-79929 (Patent Document 1). This in-hospital infection status diagnosis device is designed to provide in-hospital patients and doctors, nurses, and other in-house workers such as bacteria, From the inspection means for inspecting the infection state, storage means for storing the bacterial species data of the carrier as the examination result in the bacterial species data file, the bacterial species data of the bacterial species data file and the resident position data of the carrier In-hospital distribution data of the bacteria-type carriers is created, and data processing means for visually outputting the in-hospital distribution of the designated bacteria-type carriers among the in-hospital distribution data is provided.

  Further, as a conventional infectious disease monitoring system, there is one disclosed in Japanese Patent Laid-Open No. 2003-305010 (Patent Document 2). This infectious disease monitoring system is a means for collecting and storing test results related to infectious diseases from the outside in order to quickly and accurately constantly monitor the detection status of infectious diseases in the hospital or the distribution status of patients with infectious diseases. A means of monitoring the detection status of infectious diseases in hospitals or the distribution status of patients with infectious diseases from the test results, and related information such as the monitoring results and the test results, tabulation results, and ward maps that provide the basis for the results Means for outputting to an external storage medium, communication, e-mail or the like.

Japanese Unexamined Patent Publication No. 7-79929 JP 2003-305010 A

  However, the above-mentioned conventional technology is limited to monitoring the infection status and detection status of infectious diseases in hospitals and the distribution status of patients with infectious diseases, and outputting the monitoring results, which becomes a source of infection. The pathogen itself was not security managed as an individual. In recent years, with the development of biotechnology, establishment of a biosecurity system has been demanded, and it is important to secure security by taking into account pathogens such as bacteria and viruses that cause infectious diseases.

  An object of the present invention is to realize an advanced and safer biosecurity system against pathogens such as bacteria and viruses that cause infectious diseases.

  In order to achieve the above-mentioned object, the present invention is a biosecurity system that performs security management of a pathogen causing infectious diseases, and is attached to a pathogen container that contains the pathogen, and management information is stored in units of pathogen containers. An IC tag to be stored; a plurality of terminals that transmit / receive management information to / from the IC tag; and a server that is connected to the plurality of terminals via a communication line, and manages the plurality of terminals and the IC tag Based on transmission / reception of information, the history management of the pathogen is performed in a unified manner in the pathogen container unit by the server.

A more preferable specific configuration example of the present invention is as follows.
(1) The management information includes the pathogen type, storage state history information, location information, and sterilization treatment record information.
(2) An ultra-low temperature freezer that stores the pathogen container, the terminal provided in the ultra-low temperature freezer, and a door opening / closing authentication device that authenticates opening and closing of a door for taking in and out the pathogen container, The management information includes information of the internal temperature history of the ultra-low temperature freezer, the number of times the door is opened and closed, and the name of the individual authenticated by the door opening / closing authentication device.
(3) After the pathogen is stored in the pathogen container, history information for each pathogen unit is recorded and updated in the storage device of the server in relation to storage, transportation, experiment, and disposal processing.
(4) The plurality of terminals include a hospital terminal owned by a hospital and a laboratory terminal owned by a laboratory, and the server includes a management center server connected to the hospital terminal and the hospital terminal.

  According to the present invention, it is possible to realize an advanced and safer biosecurity system by centrally managing pathogens such as bacteria and viruses that cause infectious diseases at an individual level.

  Hereinafter, a biosecurity system according to an embodiment of the present invention will be described with reference to the drawings.

  First, the outline of the biosecurity system of the present embodiment will be described with reference to FIG. FIG. 1 is a schematic diagram of a biosecurity system 1 of the present embodiment.

  First, in the biosecurity system 1, a pathogen sample, which is a biological sample collected at a site where an infectious disease has occurred, is stored in a pathogen container 10 equipped with an IC tag 11 and managed in units of the pathogen container 10. . As a result, pathogen samples can be strictly managed at the individual level, and safe and reliable operations can be performed. The pathogen container 10 is composed of an elongated small plastic container, for example, a 1 ml tube. An IC tag 11 is attached to the pathogen container 10. For example, a small IC tag 11 using nanotechnology is embedded and attached so as not to impair the strength of the pathogen container 10. The pathogen sample is frequently repeatedly frozen and thawed, and is subjected to physical impacts such as being stored for a long time in liquid nitrogen or subjected to heat treatment. Is set so as not to lose information reliably, and there is a system that can easily write and read information.

  Secondly, in the biosecurity system 1, security management is performed by theft prevention / distribution grasping at the time of distribution using the pathogen container 10 to which the IC tag 11 is attached. Security management by theft prevention / distribution grasping is real-time management / tracking management of the pathogen container 10, accurate information transmission by information management in the pathogen container 10 unit, strict warehousing / delivery management / delivery management / delivery at the point of responsibility decomposition. Strict management such as management and lot / sorting is performed.

  Thirdly, in the biosecurity system 1, anti-theft / strict storage during storage is performed using the pathogen container 10 with the IC tag 11 attached. In this anti-theft / strict storage, automatic grasping / removing, history management of storage status, location management in storage, access control, etc. are performed.

  Fourth, in the biosecurity system 1, security management is performed by data linkage using the pathogen container 10 to which the IC tag 11 is attached and the management center server 3. In this security management based on data linkage, centralized management, monitoring, accumulation and statistics of data, accurate information management and transmission in the unit of pathogen container 10, prompt information disclosure, pathogen storage status with other research facilities in Japan and overseas Centralized management is performed.

  Fifth, in the biosecurity system 1, security management is performed based on usage confirmation / certification using the pathogen container 10 with the IC tag 11 and the clothing with the IC tag. In the security management based on confirmation of usage / certification, matching of clothing (protective clothing, hats, gloves, etc.), entrance / exit management according to the level of clothing, matching between chemicals, confirmation of procedures for experiment / use / disposal, etc. are performed. It is.

  Sixth, in the biosecurity system 1, experiment management / history grasping is performed using the pathogen container 10 to which the IC tag 11 is attached and the experimental instrument. In this experiment management / history grasp, 10 pathogen containers at the time of use and researcher's authority management, matching of pathogen container 10 with target, use history management in pathogen container unit / researcher unit, usage status (minute) Note etc.) Management etc. are performed.

  Seventh, the biosecurity system 1 uses the pathogen container 10 with the IC tag 11 attached and uses the sterilizer 7 to perform security management by management / history grasp at the time of disposal. In the security management based on the management / history grasp of the disposal process, the history management of the sterilization / inactivation process is performed.

  As a result, the biosecurity system 1 prevents theft of pathogens, prevents the occurrence of infectious diseases inside and outside the hospital, speeds up the response of the infectious diseases, prevents infection in the laboratory, prevents the pathogen container 10 from being lost, and uses waste. Prevention of infection outside the laboratory.

  Next, the overall configuration of the biosecurity system 1 will be described with reference to FIG. FIG. 2 is an overall configuration diagram of the biosecurity system 1 of the present embodiment.

  The biosecurity system 1 is connected to the management center server 3 owned by the management center 3A via the communication line 9 such as a wired LAN, wireless LAN, Internet, telephone network, radio wave, etc. The laboratory terminal 4 owned by the laboratory 4A is connected to the research facility terminal 5 owned by the research facility 5A. Here, the term “laboratory” and “research facility” are used in order to clarify that they are different research institutions. Further, the management center server 3 may be owned by the hospital 2A, the laboratory 4A, and the research facility 5A, and in this case, each terminal may be shared by the server.

  Next, the hospital terminal 2 will be described with reference to FIG. FIG. 3 is a configuration diagram of the hospital terminal 2 in the biosecurity system 1 of FIG. As this hospital terminal 2, a number already arranged in the hospital 2 </ b> A may be used.

  The hospital terminal 2 is configured by a personal computer or the like, and includes an input device 21, a control device 22, a display device 23, a storage device 24, a communication device 25, and a printer 26.

  The input device 21 has a character input unit such as a keyboard and is connected to the control device 22 so as to input the input result to the control device 22. The control device 22 is configured by a microcomputer or the like, performs predetermined processing based on the input data, the IC tag 11 and the data transmitted from the management center server 3, stores the processing result in the storage device 24, and displays the display device 23. And a function of outputting to the printer 26 and further outputting to the outside via the communication device 25. The display device 23 includes a CRT display device, a liquid crystal display device, and the like, and is connected to the control device 22 to display input contents, received contents, processing contents, and the like. The storage device 24 stores information unique to the hospital 2A (for example, registered contents in the biosecurity system 1) and is connected to the control device 22. The communication device 25 has a function of enabling the hospital terminal 2 to transmit and receive to the communication line 9 and is connected between the communication line 9 and the control device 22. The printer 26 is a plain paper printer and is connected to the control device 22. The hospital terminal 2 transmits / receives to / from the IC tag 11 of the pathogen container 10 stored in the storage 6 installed in the hospital 2 </ b> A via various communication lines (wireless and wired) 9 and the management center server 3. It is comprised so that transmission / reception may be performed.

  A hospital dedicated server may be provided in the hospital 2A, and the hospital terminal 2 may be connected to the hospital dedicated server and connected to the management center server 3 through the communication line 9 from the hospital dedicated server.

  Next, the management center server 3 will be described with reference to FIG. FIG. 4 is a configuration diagram of the management center server 3 in the biosecurity system 1 of FIG.

  As shown in FIG. 4, the management center server 3 includes an input device 31, a control device 32, a display device 33, a storage device 34, a communication device 35, and a printer 36.

  The input device 31 has an input unit such as a keyboard and is connected to the control device 32. The control device 32 is configured by a microcomputer or the like, and performs main processing in the biosecurity system 1. The display device 33 includes a CRT display device, a liquid crystal display device, and the like, and is connected to the control device 32 to display necessary transmission / reception screens and input screens. The storage device 34 stores information necessary for processing of the control device 32 and is connected to the control device 32. The storage device 34 includes software for performing processing of the biosecurity system 1 and a traceability database 34a (see FIGS. 1 and 6). The communication device 35 has a function of enabling the control device 32 to transmit / receive to / from the communication line 9 and is connected between the communication line 9 and the control device 22.

  Next, the laboratory terminal 4 will be described with reference to FIG. FIG. 5 is a configuration diagram of the laboratory terminal 4 in the biosecurity system 1 of FIG.

  As shown in FIG. 5, the laboratory terminal 4 includes an input device 41, a control device 42, a display device 43, a storage device 44, a communication device 45, and a printer 46.

  The input device 41 has a character input unit such as a keyboard, and is connected to input the input result to the control device 42. The control device 42 is configured by a microcomputer or the like, performs predetermined processing based on input data, the IC tag 11 and data transmitted from the management center server 3, stores the processing result in the storage device 44, and displays the display device 43. And a function of outputting to the printer 46 and further to the outside via the communication device 45. The display device 43 includes a CRT display device, a liquid crystal display device, and the like, is connected to the control device 42, and displays a transmission / reception screen, an input screen, and the like necessary for the laboratory 4A. The storage device 44 stores information unique to the laboratory 4A (for example, registered contents in the biosecurity system) and is connected to the control device 42. The communication device 45 has a function of enabling the control device 42 to transmit / receive to / from the communication line 9 and is connected between the communication line 9 and the control device 22. The printer 46 is a plain paper printer and is connected to the control device 42. The laboratory terminal 4 transmits / receives to / from the IC tag 11 of the pathogen container 10 stored in the storage 6 installed in the laboratory 4A via various communication lines (wireless and wired) 9, the laboratory 4A Transmission / reception with the IC tag 11 of the pathogen container 10 sterilized by the sterilization apparatus 7 installed therein and transmission / reception with the management center server 3 are performed.

  A laboratory dedicated server may be provided in the laboratory 4A, and the laboratory terminal 4 may be connected to the laboratory dedicated server, and may be connected to the management center server 3 through the communication line 9 from the laboratory dedicated server. .

  Since the research facility terminal 5 is basically the same as the laboratory terminal 4, a detailed description thereof is omitted.

  Next, an example of the IC tag 11 used in the biosecurity system 1 of FIG. 1 will be described. This IC tag 11 is a tag (tag) incorporating a small IC (integrated circuit) chip of 1 mm 2 or less. A wireless antenna is attached, and communication with the reader is possible without contact. In addition, it is possible to record a large amount of data such as date of management, pathogen information, distribution history, etc., and it is difficult to duplicate or forge information, and information can be rewritten or added. The IC tag 11 includes an IC chip and an antenna that also serves as a power source. The IC chip includes a microcomputer for decoding and responding to received radio waves and a memory for storing its own identification number. The IC tag 11 is read by a system called RFID (Radio Frequency IDentification). When a radio wave is emitted from the reader toward the pathogen container 10 to which the IC tag 11 is attached, the antenna of the IC tag 11 resonates to generate electricity and activate the IC chip. The activated IC chip returns the stored information by radio waves. The reading device decodes the IC tag information from this reply radio wave. This reading device may be built in each of the terminals 2, 4, 5, and may be provided independently outside each of the terminals 2, 4, 5.

  By using the IC tag 11 as described above, the following advantages can be obtained. Since information is exchanged by radio waves, reading is fast, and even if the IC tag 11 is separated from the reading device, it can be read without contact. In addition, a package containing a plurality of IC tags can be read instantaneously, and traceability can be managed. Furthermore, the security of information can be improved by encrypting the identification number.

  Next, the security management during distribution in the biosecurity system 1 will be specifically described with reference to FIG. FIG. 6 is an explanatory diagram of security management related to theft prevention / distribution grasping during distribution in the biosecurity system 1 of the present embodiment.

  For example, when an emerging or re-emerging infectious disease occurs, infectious pathogens are collected as samples from people and their clothes on site. This must be managed in an appropriate manner, transported quickly and diagnosed. At that time, since it is a dangerous infectious agent, it is strictly enclosed in secondary and tertiary containers and transferred. However, in the past, what the pathogen sample indicates was managed with handwritten labels or barcode labels affixed on the packaging, making it difficult to read or physically erasing the label. , The label was peeled off, etc., causing valuable information to be mistakenly transmitted or lost.

  Therefore, in this embodiment, the collected pathogen sample is stored in the pathogen container 10 equipped with the IC tag 11, and the pathogen container 10 is stored in the secondary container 12 (see FIG. 8) and the tertiary container 13 (see FIG. 6). While being tightly sealed, it is transported between the hospital 2A, the laboratory 4A, and the research facility 5A using the transport mechanism 14, and can be transmitted to and received from the IC tag 11 from the outside of the tertiary container 13 at the time of the transport.

  Receipt / shipment information and location information for each pathogen container 10 with the IC tag 11 mounted between the terminals 2, 4, 5 of the hospital 2A, laboratory 4A, and research facility 5A and the management center server 3 of the management center 3A. The attribute information and the like are transmitted / received, and the transmission / reception status thereof is stored in the traceability database 34a of the management center server 3. Delivery information, GPS information (current position information), etc. are received between the terminal (not shown) of the transport facility 14 and the management center server 3 of the management center 3A for each pathogen container 10 with the IC tag 11 attached. The reception status is stored in the traceability database 34 a of the management center server 3. In these, the IC tag 11 is used for collective collection of information, collective inspection at the time of receipt / shipment, and offline information transmission, and can ensure high security while improving workability and preventing omission of actual product confirmation. it can. The traceability database 34a is used for centralized management of information on the pathogen container 10 unit and centralized management of the current position, and can clarify the responsibility based on the movement / delivery history and ensure high security. Then, after the pathogen is stored in the pathogen container 10, history information for each pathogen is recorded and updated in the traceability database 34 a of the storage device 34 in relation to storage, transportation, experiment, and disposal processing.

  Next, security management during storage in the biosecurity system 1 will be described with reference to FIG. FIG. 7 is an explanatory diagram of security management related to theft prevention / strict storage during storage in the biosecurity system 1 of the present embodiment.

  The storage device for the pathogen container 10 installed in the hospital 2A, the laboratory 4A, and the research facility 5A includes an ultra-low temperature freezer 6 that stores the pathogen container 10, and an information processing device 61 provided in the ultra-low temperature freezer 6. And a door opening / closing authentication device for authenticating opening / closing of the door for putting in and out the pathogen container 10 by an individual. The management information at the time of storage includes information such as the internal temperature history, the number of times of opening / closing the door, the operation history, the location of the pathogen container 10 inside, and the name of the individual authenticated by the door opening / closing authentication device. With these, high security can be obtained. Note that the information processing apparatus 61 transmits and receives to / from each of the terminals 2, 4, and 5, and may be shared with these terminals. The pathogen sample stored in the pathogen container 10 is stored for a long time in the ultra-low temperature freezer 6 using liquid nitrogen, but the IC tag 11 of this embodiment is configured so as not to lose information even in that case. Yes.

  Next, security management by data cooperation in the biosecurity system 1 will be described with reference to FIG. FIG. 8 is an explanatory diagram of security management by data linkage in the biosecurity system 1 of the present embodiment.

  When the pathogen container 10 is received and discharged at the hospital 2A, the laboratory 4A, and the research facility 5A, an IC tag is provided from the outside of the secondary container 12 that is a package containing a plurality of pathogen containers 10 by the terminals 2, 4, and 5. 11 information is read or written. Each terminal 2, 4, and 5 transmits these pieces of information to the management center server 3 and registers them in the traceability database 34a. As a result, each of the terminals 2, 4, and 5 can accurately refer to the distribution history of the pathogen container 10 from the management center server 3, confirm the location, and confirm the inventory amount.

  Next, security management at the time of disposal in the biosecurity system 1 will be described with reference to FIG. FIG. 9 is an explanatory diagram of security management by management / history grasp at the time of disposal in the biosecurity system 1 of the present embodiment.

  The pathogen sample (microorganism) for which the experiment has been completed is sterilized and inactivated using the sterilizer 7. In this case, a plurality of pathogen containers 10 are accommodated in the sterilizer 7 and sterilized, but since path management of disposal processing and sterilization / inactivation processing for each pathogen container 10 is performed, pathogens can be safely and securely provided. The sample can be discarded. An example of this is shown in list form in FIG.

  According to the present embodiment, it is possible to provide a biosecurity system that integrates and manages information that has conventionally been scattered in pathogen transfer and processing. It also protects against possible threats such as sample theft, emerging, re-emerging infectious diseases, delayed response, laboratory infection, sample dissipation, waste infection outside the laboratory, Accurate management method (BioSecurity & BioSafety) can be realized.

It is a schematic diagram of the biosecurity system of one example of the present invention. It is a whole block diagram of the biosecurity system of a present Example. It is a block diagram of the hospital terminal in the biosecurity system of FIG. It is a block diagram of the management center server in the biosecurity system of FIG. It is a block diagram of the laboratory terminal in the biosecurity system of FIG. It is explanatory drawing of the security management which concerns on theft prevention at the time of physical distribution / physical distribution grasp in the biosecurity system of a present Example. It is explanatory drawing of the security management which concerns on theft prevention at the time of storage / strict storage in the biosecurity system of a present Example. It is explanatory drawing of the security management by the data cooperation in the biosecurity system of a present Example. It is explanatory drawing of the security management by management / log | history grasping | ascertaining at the time of the discard process in the biosecurity system of a present Example.

Explanation of symbols

  DESCRIPTION OF SYMBOLS 1 ... Biosecurity system, 2 ... Hospital terminal, 2A ... Hospital, 3 ... Management center server, 3A ... Management center, 4 ... Laboratory terminal, 4A ... Laboratory, 5 ... Research facility terminal, 5A ... Research facility, 6 ... Storage (ultra-low temperature freezer), 7 ... sterilizer, 9 ... communication line, 10 ... pathogen container, 11 ... IC tag, 12 ... secondary container, 13 ... tertiary container, 23a ... traceability database, 61 ... information processing device.

Claims (5)

A biosecurity system that performs security management of pathogens that cause infections,
An IC tag attached to a pathogen container for storing the pathogen and storing management information in units of pathogen containers;
A plurality of terminals that transmit and receive management information to and from the IC tag;
A server connected to the plurality of terminals via a communication line,
A biosecurity system characterized in that, based on transmission / reception of management information between the plurality of terminals and the IC tag, the pathogen history is centrally managed by the server for each pathogen container.   2. The biosecurity system according to claim 1, wherein the management information includes a type of the pathogen, storage history information, location information, and sterilization record information.   2. The biosecurity system according to claim 1, wherein the ultra-low temperature freezer for storing the pathogen container, the terminal provided in the ultra-low temperature freezer, and door opening / closing for authenticating opening and closing of a door for taking in and out the pathogen container by an individual. And the management information includes information on the internal temperature history of the ultra-low temperature freezer, the number of times of opening and closing the door, and the name of the individual authenticated by the door opening and closing authentication device. Security system.   2. The biosecurity system according to claim 1, wherein pathogen unit history information is recorded and updated in the storage device of the server in relation to storage, transportation, experimentation, and disposal processing after the pathogen is stored in the pathogen container. A biosecurity system characterized by   2. The biosecurity system according to claim 1, wherein the plurality of terminals include a hospital terminal owned by a hospital and a laboratory terminal owned by a laboratory, and the server is connected to the hospital terminal and the hospital terminal. A biosecurity system including a management center server.

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