JP2003119490A - Psychosedative perfume composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a psychosedative perfume composition containing a newly found psychosedative ingredient. SOLUTION: This psychosedative perfume composition contains one or more ingredients selected from terpinyl acetate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysanthenone, liral, lilial, Β-phenylethylalcohoo, γ- methylionone, iso-e-super, Z-3-hexenyl salicylate, p-methylphenylacetoaldehyde, limonene, ocimene, helional, linalyl acetate, geranyl acetate, geraniol, dedione, linalool, citronellol, and γ-hexalactone whose psychosedative effects are found, respectively.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a fragrance composition having a specific psychological effect, and more specifically, relates to a sedative fragrance composition having a sedative effect. Is.

[0002]

2. Description of the Related Art It has been revealed that various stresses have various physiological or psychological effects. Particularly, in a modern society which is also called a stress society, how to deal with various stresses is a very important issue.

Providing mental healing can be mentioned as a means for reducing the adverse psychological effects of stress on humans. As a typical mode of this healing, there is a sedation of the irritated spirit due to various stresses.

Recently, aromatherapy has been attracting attention as a means of calming the mind. It has been traditionally confirmed that lavender oil, chamomile oil, etc. have a soothing effect on the mind in aromatherapy, and since these can exert a soothing effect due to the scent, it is possible to achieve a very mild soothing effect. It has an advantage that an effect can be obtained.

However, the selection and blending of the natural fragrances which should exert a psychological sedative effect depend largely on the empirical judgment of the aromatherapy expert, and the effect is not always clear. It is considered that this is largely due to the fact that natural flavors such as essential oils used for aromatherapy are composed of various components.

Therefore, for example, Japanese Patent Laid-Open No. 6-172781.
In the publication, 1,3-dimethoxy-5-methylbenzene has a sedative effect, and the effect is exhibited even by adding this to a fragrance or the like and vaporizing and sucking it, and further, the fragrance of the compound itself is strong. Therefore, it has been reported that this compound can be added to various fragrances and used to exert a psychological sedative effect.

[0007]

However, in order to actually obtain a psychological sedative effect in various life situations and aromatherapy, many people use the scent in combination depending on their tastes and life situations. It is necessary to be able to easily prepare an appropriate formulation depending on the compatibility with various flavors. To do so, it is necessary to find substances that can exert a wider variety of psychological sedative effects.

[0008] Therefore, the problem to be solved by the present invention is to find a new component which has a psychological sedative effect, and to produce a sedative fragrance composition containing the same.

[0009]

[Means for Solving the Problems] In order to solve this problem, the present inventor has investigated a sedative effect of many ingredients. As a result, among the components contained in natural essential oils, terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysanthenone, lyral, lilial, β-phenylethyl alcohol, γ-methylionone, iso-E-・ Super, Z-3-hexenyl salicylate, p-methylphenylacetaldehyde (also called syringaldehyde), limonene, ocimene, helionar, linalyl acetate, geranyl aceto,
Geraniol, hedion (also known as methyldihydrojasmonate), linalool, citronellol, and γ-hexalactone were found to have a psychological sedative effect (hereinafter also referred to as psychosedative effect), and for sedation The present invention relating to a fragrance composition has been completed.

That is, the present invention relates to terpinyl butyrate, γ
-Nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysanthenone,
Liral, lilial, β-phenylethyl alcohol, γ-methylionone, iso-E super, Z-
3-hexenyl salicylate, p-methylphenylacetaldehyde, limonene, ocimene, helional, linalyl acetate, geranyl acetate, geraniol,
Hedion, linalool, citronellol, and γ
-One or two selected from the group consisting of hexalactone
The invention provides a sedative fragrance composition (hereinafter, also referred to as the present sedative composition) containing one or more kinds of components.

In the present invention, the fragrance composition for mental sedation means a fragrance composition that exerts the effect of calming the user and giving a feeling of relaxation by using the fragrance composition. A sedative composition for mental sedation is contained in an external composition such as a cosmetic, a deodorant for a room, a sundries such as an aroma candle, a food composition, etc., to have a sedative effect on these products. Can be granted. The psychosedative effect means, for example, an effect of relaxing a mood by releasing a physiological psychological state such as irritability and excitement that humans experience in daily life, and a sensory test using a panel or a mental Index that can detect general sedation (eg CN
It can be confirmed by V measurement).

[0012]

BEST MODE FOR CARRYING OUT THE INVENTION Embodiments of the present invention will be described below. Terpinyl butyrate, that is, Terpinylbutyrate, which is a contained component of the present sedative composition, is known as a fragrance having a rosemary-like balsamic and floral scent. Terpinyl butyrate is manufactured by a conventional method,
It can be used in the present invention, and a commercially available product can also be used.

Γ-Nonalactone, that is, γ-Nonalac
Ton is known as a fragrance with a creamy coconut scent. γ-Nonalactone can be used in the present invention after being isolated and purified from an essential oil such as peach by a conventional method, or a commercially available product can also be used.

Acetyl iso Eugenol
genol), that is, Methoxy-4-acetoxypropenylbenzene
Is known as a perfume with a sweet floral note, like perilla and balsamic, carnation.
Acetylisoeugenol can be produced by a conventional method and used in the present invention, or a commercially available product can be used.

Methyl anisa
te is known as a fragrance with a sweet herbal and anise scent reminiscent of lilac and magnolia. Methyl anisate can be produced by a conventional method and used in the present invention, or a commercially available product can also be used.

Terpineol, that is, Terpineol
Is known as a fragrance having a lilac-like odor. Terpineol can be used in the present invention after being isolated and purified from an essential oil such as orange by a conventional method, and a commercially available product can also be used.

Nellore, or Nerol, is known as a fragrance having an aroma similar to geraniol. Nellore can be used in the present invention after being isolated and purified from an essential oil such as neroli by a conventional method, and a commercially available product can also be used.

Chrysantheno, or Chrysantheno
ne is known as a fragrance having a metallic herbal green scent. Chrysanthenone can be used in the present invention after being isolated and purified from an essential oil such as Artemisia by a conventional method, or a commercially available product can be used.

Lyral, or Lyral, is known as a fragrance having a lily of the valley aroma. Lillard
It can be produced by a conventional method and used in the present invention, or a commercially available product can be used.

Lilial, or Lilial, is known as a fragrance having a lily of the valley aroma. Lilyal can be produced by a conventional method and used in the present invention, or a commercially available product can be used.

Β-Phenylethyl alcohol, that is, β-Phenylethyl alcohol, is known as a fragrance having a mild rose-like odor. β-Phenylethyl alcohol can be isolated and purified from an essential oil such as rose by a conventional method and used in the present invention, or can be used as a commercial product.

Γ-Methylionone, that is, γ-Meth
yl ionone is known as a fragrance having a mild violet-like or Oris-like odor. γ-Methylionone can be produced by a conventional method and used in the present invention, or a commercially available product can be used.

Iso E or Super E
Super is known as a fragrance with a Woody Amber-like scent. Iso-E-Super can be produced by a conventional method and used in the present invention, or a commercially available product can be used.

Z-3-hexenyl salicylate, that is, cis-3-Hexenyl salicylate, is known as a fragrance having a balsamic floral-like aroma. Z-3
-Hexenyl salicylate can be produced by a conventional method and used in the present invention, or a commercially available product can be used.

[0025] p-Methylphenylacetaldehyde, that is, p-Methylphenylacetaldehyde, is known as a flavoring agent having fruity and green scents. p-
Methylphenylacetaldehyde can be used in the present invention after being isolated and purified by a conventional method from an essential oil such as corn, or a commercially available product can be used.

Limonene, or Limonene, is known as a fragrance with a fresh citrus-like aroma. Limonene can be used in the present invention after being isolated and purified from an essential oil such as orange by a conventional method, and a commercially available product can also be used.

Ocimene, that is, Ocimene, is known as a fragrance having a green, woody, and herbal scents reminiscent of anise and citrus lime. Ocimene can be used in the present invention after being isolated and purified from an essential oil such as thyme by a conventional method, or a commercially available product can be used.

Helional, or Helional, is known as a perfume with a sweet heliotrope, an anise-like floral odor. Helional can be produced by a conventional method and used in the present invention, or a commercially available product can be used.

Linalyl acetate, that is, Linalyl
Acetate is known as a perfume with a fresh and sweet fruity floral scent. Linalyl acetate can be used in the present invention after being isolated and purified from an essential oil such as lavender by a conventional method, or a commercially available product can be used.

Geranyl acetate, namely Geranyl
Acetate is known as a fragrance with a sweet rose-like odor. Geranyl acetate can be used in the present invention after being isolated and purified from an essential oil such as lemon by a conventional method, or a commercially available product can be used.

Geraniol, or Geraniol, is known as a fragrance with a rose-like aroma. Geraniol can be used in the present invention after being isolated and purified by a conventional method from an essential oil such as geranium, or a commercially available product can be used.

Hedion, or Hedione, is known as a fragrance having a jasmine-like floral odor. Hedion, for example, from essential oils such as jasmine,
It can be isolated and purified by a conventional method and used in the present invention, or a commercially available product can be used.

Linalool, or Linalool, is known as a fragrance having a lily of the valley aroma. Linalool can be used in the present invention after being isolated and purified from an essential oil such as orange by a conventional method, or a commercially available product can also be used.

Citronellol, namely Citronellol
Is known as a fragrance with a fresh rose-like aroma. Citronellol, for example, from essential oils such as rose,
It can be isolated and purified by a conventional method and used in the present invention, or a commercially available product can be used.

Γ-Hexalactone, that is, γ-Hexal
Actone is known as a fragrance with a warm herbal, tobacco and coumarin-like odor. γ-Hexalactone can be isolated and purified from essential oils such as apricot by a conventional method and used in the present invention, or a commercially available product can also be used.

The present sedative composition is an essential component, terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysanthenone, lyral, β-.
Phenylethyl alcohol, γ-methylionone, Iso E super, Z-3-hexenyl salicylate,
Perfume composition consisting of one or more components selected from the group consisting of p-methylphenylacetaldehyde, limonene, ocimene, helional, linalyl acetate, geranyl acetate, geraniol, hedion, linalool, citronellol, and γ-hexalactone. May be a thing, in order to improve the palatability of the fragrance, other fragrance ingredients, essential oils, etc., the desired sedative effect, within the limit that is not offset by the harmony effect or masking effect, You may contain suitably. The present sedative composition can be used mainly as a mixed fragrance. Further, the present sedative composition may also contain general components that can be generally contained in the fragrance composition, for example, antioxidants, preservatives, chelating agents, ultraviolet absorbers, pigments and the like. .

The present sedative composition can be made to exhibit a sedative action mainly by being added as a compounded fragrance to an object capable of containing a fragrance. Examples of such objects include, but are not limited to, external compositions such as cosmetics, deodorants and fragrances for rooms, sundries such as aroma candles, and food compositions.

The content of the present sedative composition in these objects can be freely selected according to the type of the object and the type of perfume to be selected, etc., within the limit that the sedative effect can be exerted. It is possible, and usually, it is possible to select according to the general content of the compounded fragrance. Generally, it is preferably 0.01 to 50.0 mass% with respect to the object, particularly preferably 0.1 to 20.0 mass%, and 1.0 to In many cases, 10.0% by mass is very suitable.

When the present sedative composition is contained in an object, the components having a sedative effect (terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysanthenone, lillar, liaral, β-phenylethyl alcohol, γ-methylionone, iso-E super,
One or more selected from the group consisting of Z-3-hexenyl salicylate, p-methylphenylacetaldehyde, limonene, ocimene, helional, linalyl acetate, geranyl aceto, geraniol, hedion, linalool, citronellol, and γ-hexalactone. ), The total amount is 0.001 to the object.
It is generally preferable that the content is 50.0% by mass, and the content of 0.01 to 20.0% by mass is particularly preferable in view of the palatability, and further 1.0 to 10.0
% Is often very suitable. When the content of the contained component is less than 0.001% by mass with respect to the object, there is a tendency that a sufficient sedative effect is not exhibited even if the influence of other compounding components is minimized.
Even if blended in an amount of more than mass%, the improvement of the psychosedative effect, which is commensurate with the content of the component having the psychosedative effect, is not observed, and the balance of aroma tends to be generally unfavorable.

In the object containing the present sedative composition, other than the present sedative composition, general constituents depending on the type of the object do not lose the intended effect of the present invention. Used within range.

For example, when the object is an external composition such as cosmetics, the specific formulation of the external composition (liquid agent, powder agent, granule agent, aerosol agent, solid agent, gel agent, etc.) In addition to the present sedative composition, the general components contained in these externally applied compositions can be contained in addition to the sedative composition, depending on the product form.

The cosmetics, which is one of the most preferable embodiments of the composition for external use, include, for example, perfume, eau de toilette, cologne, creams / milky lotions, lotions, foundations, white powder, lipstick, pomade, Soap, shampoo / rinse, body shampoo, body rinse, body powder, bath agent, etc. are exemplified as specific product forms.

Examples of daily commodities include room fragrances, deodorants, and aroma candles as specific product forms. The present invention is also an invention which provides a sedative method for sedating a psyche by inhaling the present sedative composition.

The subject who inhales the present sedative composition is
Usually, it is a human being, but it may be a mammal such as a dog or a cat. In addition, the means for inhaling is usually carried out through an object (a composition for external use, a miscellaneous goods, a food composition, etc.) containing the composition for sedation. That is, a normal use mode of these objects, or a specified use mode (for example, use of the external composition such as cosmetics in the outer skin, ignition of aroma candles that are miscellaneous goods, fragrance and deodorant According to (installation and spraying in a room, eating and drinking of food compositions, etc.), the inhalation target inhales the composition for mental sedation contained in the object, and the sedative component in the composition for mental sedation,
The spirit to be inhaled is calmed down.

[0045]

EXAMPLES The present invention will be described in more detail below with reference to examples. In addition, the compounding amount represented by% is the mass% with respect to a compounding object. CNV test Contingent Negative Variat
The sedative effect was examined by measuring the change in the negative potential called ion). CNV is caution,
It is known as a gradual change in the brain potential associated with psychological processes such as expectations and expectations, and changes in consciousness level.

In order to search for a sample having a psychosedative effect, an optical signal which means the start of exercise continues 2 seconds after the warning stimulus sound, and at the same time when the light is recognized, a panel button is clicked to perform an exercise reaction. Perform the tests required by. In this series of repetitions, the sample was placed on the tip of the panel nose (about 10 cm).
It is placed on the above), and the panel can recognize the scent of the sample with breathing. The electrodes for CNV measurement are mounted on the frontal part of the panel and the electrogram between the earlobe is measured. It should be noted that when humans are internally taken with caffeine, which has a wakefulness effect, the amplitude of CNV increases, and when nitrozepam, which has a sedative effect, is inhaled, C
It has been reported that the amplitude of NV is reduced.

The fluctuation of CNV amplitude is 400 after sound stimulation.
Remarkably appears in the initial component of ~ 1000 msec. Therefore, the varying area of the CNV amplitude in this section was expressed as a percentage (%) with the blank (in the case of odorless stimulation) as 100%, and this was used as an index for the psychosedative effect. When the area change is 100% or less, the sedative effect is shown, and when the area change is 100% or more, the wakefulness effect is shown.

Test Examples As samples, terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysanthenone, lyral, lilial, β-phenylethyl alcohol, γ-methylionone, iso-E-super, Z -3-Hexenyl salicylate, p-methylphenylacetaldehyde, limonene, ocimene, helional, linalyl acetate, geranyl acetate, geraniol, hedion, linalool, citronellol, and 1% ethanol of γ-hexalactone (each of which is a commercial product) A solution and 3-dimethoxy-5-methylbenzene (hereinafter, referred to as a sedative effect in JP-A-6-172781) have been reported.
(Also called DMMB) and 1 of lemon oil (each using a commercial product), which has been traditionally recognized for its spiritually enhancing effect.
% Ethanol solution was prepared, and the CNV test was conducted on the panel as 5 healthy adult women in the same manner as described above.

The results are shown in FIG. According to FIG. 1, terpinyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysanthenone, lyral, lilial, β-phenylethyl alcohol, γ-methylionone, iso.
E-super, Z-3-hexenyl salicylate, p
DMMB for -methylphenylacetaldehyde, limonene, ocimene, helional, linalyl acetate, geranyl acetate, geraniol, hedion, linalool, citronellol and γ-hexalactone.
Similarly, it was revealed that a psychosedative effect was observed (lemon oil confirmed a psychoactive effect).

Specific prescription examples of the present sedative composition will be shown below as examples. The present sedative compositions of Examples 1 to 9 were confirmed to have a sedative effect by the above CNV test.

[0051] Example 1 mental sedative perfume composition Ingredients Amount (parts by weight) γ-Nonalactone 0.2 Methyl anisate 2.0 p-Methylphenylacetaldehyde 2.0 Ocimene (1%) 0.5 γ-Hexalactone 1.0 Bergamot oil 10.0 Methyl dihydro jasmonate (Hedione) 20.0 Linalool 28.0 Orange oil 1.0 Linalool oxide 5.0 Phenylethyl alcohol 5.0 Benzyl alcohol 1.0 Benzaldehyde 1.0 Indol (10%) 0.5 Abs. Cassis 2.0 Nerol 2.0 Abs. Jasmin 1.0 Iso E super 5.0 Galaxolide (50%) 10.0 Bacdanol 1.0 Anis alcohol 1.0 DPG 0.8

[0052] Example 2 mental sedative perfume composition Ingredients Amount (parts by mass) Terpinyl butylate 1.0 γ-Nonalactone 0.1 Ocimen (1%) 0.5 Methyl dihydro jasmonate (Hedione) 20.0 Vertofix coeur 15.0 Polysantol 10.0 Galaxolide (50%) 10.0 Bergamot oil 9.0 Orange oil 4.0 Ethyllinalool 3.0 Lilia1 2.0 Bacdanol 1.0 Linalool 1.0 Coumarin 1.0 Ambroxane 1. 0 Citronellol 1.0 β-Phenylethyl alcohol 1.0 Calone (1%) 1.0 Pine oil 1.0 Benzyl acetate 0.5 Stemone 0.5 Terpineol 2.0 Damascone alpha (10%) 0.3 Allylamyl glycolate 0 2 Evernyl 0.2 Triplal 0.2 DPG 13.5

[0053] Example 3 mental sedative perfume composition Ingredients Amount (parts by mass) Terpinyl butylate 1.0 γ-Nonalactone 0.2 Methyl anisate 1.0 Chrysantenone 0.5 p-Methylphenylacetaldehyde 2.0 Hexalactone gannma 1.0 Methyl dihydro jasumonate (Hedion) 15.0 Lyral 13.0 Iso E super 12.0 Galaxolide (50%) 10.0 Orange oil 5.0 Linalool 15.0 γ-Methyl ionone 5.0 Limonene 10.0 cis-3-Hexenyl salicylate 2.0 β-Naphthylmethyl ether 1.0 Santalex 1.0 Mandarine oil 1.0 Rose oil 0.5 Laurel leaf oil 0.5 Allylamyl glycolate 0.3 Damacenone 0.2 DPG 2.8

[0054] Example 4 mental sedative perfume composition Ingredients Amount (parts by mass) Terpinyl butylate 1.0 γ-Nonalactone 0.2 Methyl anisate 1.0 p-Methylphenylacetaldehyde 2.0 γ-Hexalactone 0.5 β-Phenylethyl alcohol 10.0 Limonene 10.0 Methyl dihydro jasmonate (Hedione) 10.0 Lyral 10.0 β-Ionone 7.0 Geranyl acetate 1.0 Citronellol 7.0 Geraniol 2.0 Bergamot oil 5.0 Linalool 5 .0 Hexyl salicylate 5.0 Galaxolide (50%) 5.0 cis-3-Hexenyl salicylate 5.0 Benzyl acetate 5.0 Lime oil 3.0 Mandarin oil 2.0 Rose oil 2.0 Abs. Jasmin 0.5 cis-3-Hexenol 0.2 DPG 0.6

[0055] Example 5 mental sedative perfume composition Ingredients Amount (parts by mass) Acetyl iso Eugenol 2.0 Bacdanol 2.5 Bergamot oil 5.0 Grapefruit oil 4.0 Linalool 3.0 Linalyl acetate 3. 0 Cedramber 1.5 Coumarin 1.0 Methyl dihydro jasmonate (Hedione) 30.0 Ambroxane 0.5 Cardamon oil 0.5 Geranium oil 0.5 Limonene 3.0 Allyl amyl glycolate 0.1 Helional 1.0 Damascenone (10% ) 0.2 Cassis base 345B 1.0 Benzyl acetate 1.0 Iso E super 20.0 Habanolide 8.0 Musk T 5.0 Ethyl linalool 5.0 Lavandin oil 2.0 DPG 0.2

[0056] Example 6 mental sedative perfume composition Ingredients Amount (parts by mass) Acetyl iso Eugenol 1.0 Methyl dihydro jasmonate (Hedione) 20.0 Iso E super 15.0 Bergamot oil 10.0 DPG 5 2 Linalyl acetate 5.0 Habanolide 5.0 Dihydro myrcenol 5.0 Vertofix coeur 5.0 Bacadanol 3.0 Linalool 3.0 Musk T 3.0 Lavandin oil 3.0 Lyral 3.0 Coumarin 2.0 Limonene 2. 0 Patchouli oil 2.0 Citronellol 2.0 β-Phenylethyl alcohol 2.0 Vetiver oil 1.0 Ambroxane 0.5 Damascenone (10%) 0.5 Benzyl acetate 0.5 Evernyl 0.5 Eugenol 0.2 Jasmin oil 0 2 Vanillin 0.1 Cinamon bark oil 0.1 Galbanum oil 0.1 Allylcyclohexyl propionate 0.1

[0057] Example 7 mental sedative perfume composition Ingredients Amount (parts by mass) Acetyl iso Eugenol 5.0 Methyl dihydro jasmonate (Hedione) 15.0 Lyral 13.0 Iso E super 12.0 Galaxolide (50 %) 10.0 Orange oil 5.0 Linalool 20.0 γ-Methyl ionone 5.0 Limonene 5.0 cis-3-Hexenyl salicylate 2.0 β-Naphthylmethyl ether 1.0 Santalex 1.0 Mandarine oil 1.0 Rose oil 0.5 Laurel leaf oil 0.5 Allylamyl glycolate 0.3 Damascenone (10%) 0.2 DPG 3.5

[0058] Example 8 mental sedative perfume composition Ingredients Amount (parts by mass) Acetyl iso Eugenol 2.0 β-Phenylethyl alcohol 12.0 Limonene 10.0 Methyl dihydro jasmonate (Hedione) 10.0 Lyral 10 .0 β-Ionone 7.0 Citronellol 7.0 Geraniol 3.0 Bergamot oil 5.0 Linalool 5.0 cis-3-Hexenyl salicylate 5.0 Benzyl acetate 5.0 Lime oil 3.0 Mandarine oil 2.0 Rose oil 2.0 Abs. Jasmin 0.5 cis-3-Hexenol 0.2 DPG 1.3

[0059] Example 9 mental sedative perfume composition Ingredients Amount (parts by mass) Limonene 8.0 Linalool 10.0 Linalyl acetate 5.0 Bergamot oil 5.0 Liffarome 0.05 Benzyl acetate 5.0 β -Phenylethyl alcohol 8.0 Lilial 5.0 Lyral 3.0 β-ionone 0.5 Methyl dihydro jasmonate (Hedione) 15.0 α-Hexyl cinnamic aldrhyde 10.0 p-Methylphenylacetaldehyde 2.0 Helional 0.5 Aldehyde C- 14 0.1 Iso E Super 5.0 Galaxolide (50%) 10.0 Ethylene brassylate 3.0 Benzyl benzonate 4.85

Examples of typical product forms of externally applied compositions or sundries containing the present sedative composition are shown below as examples. The externally applied compositions or miscellaneous goods of these Examples were found to have a sedative effect by a sensory test in a typical use mode of each product form.

[0061] Example 10 baths Ingredients Amount (parts by mass) mental sedative perfume composition for sodium bicarbonate 70.0 anhydrous sodium sulfate 28.8 Example 3 1.0 Dye Y-202-1 0 .2 <Manufacturing Method> The components excluding the sedative composition for mental sedation were stirred with a V-type mixer until uniform, then the composition was added, and the mixture was further stirred until uniform until a bath agent was added. Obtained.

Example 11 Gel Fragrance Blending Component Blending Amount (parts by Mass) Carrageenan 3.0 Propylene Glycol 2.0 Propylparaben 0.3 Psychologically Stimulating Fragrance Composition of Example 3 5.0 Ion Exchange Water 89 0.7 <Production Method> Carrageenan, propylene glycol and propylparaben were mixed and ion-exchanged water was added with stirring, and this was heated with gentle stirring until the temperature reached about 80 ° C. After that, the temperature is adjusted to about 65 ° C., the sedative composition for mental sedation is added to the mixture by a homogenizer at 3000 rpm while stirring to make a uniform phase, which is then poured into a predetermined container and naturally cooled to obtain a gel fragrance. It was

[Example 12] Liquid type fragrance blending component blending amount (parts by mass) 95% ethanol 25.0 surfactant 5.0 sedative composition for mental sedation of Example 3 3.0 ion-exchanged water 67. 0 <Manufacturing Method> Each component except ion-exchanged water was mixed, and ion-exchanged water was added to the mixture while stirring gently to obtain a liquid type fragrance. Polyoxyethylene nonylphenyl ether EO-13 was used as the surfactant.

Example 13 Liquid type deodorant compounding ingredient compounding amount (parts by mass) Deodorant undiluted solution FS-500M (manufactured by Shiraimatsu Shinyaku Co., Ltd.) 5.0 95% ethanol 10.0 Surfactant 10.0 Fragrance composition for mental sedation of Example 2 10.0 Ion-exchanged water 65.0 <Production method> Mixing components other than ion-exchanged water and adding ion-exchanged water with gentle stirring to remove deodorant (liquid) Type). Polyoxyethylene nonylphenyl ether EO-10 was used as the surfactant.

[Example 14] Aerosol type deodorant compounding ingredient compounding amount (parts by mass) Deodorant stock solution FS-500M 5.0 95% ethanol 20.0 Mental soothing fragrance composition of Example 2 10.0 Ion Exchanged water 40.0 Liquefied petroleum gas (4Kg / cm ² · 20 ° C) 25.0 <Production method> Components other than liquefied petroleum gas are mixed and stirred to homogenize, put a prescribed amount in an aerosol container and attach a valve. After that, liquefied petroleum gas was injected to obtain a deodorant (aerosol type).

[0066] Example 15 baths Ingredients Amount (parts by weight) of sodium bicarbonate 70.0 mental sedative perfume composition for anhydrous sodium sulfate 28.8 Example 7 1.0 Dye Y-202-1 0 .2 <Manufacturing Method> The components excluding the sedative composition for mental sedation were stirred with a V-type mixer until uniform, then the above fragrance composition was added, and the mixture was further stirred until uniform, and a bath agent was prepared. Got

[Example 16] Gel fragrance compounding ingredient compounding amount (parts by mass) Carrageenan 3.0 Propylene glycol 2.0 Propylparaben 0.3 Psychologically relaxing fragrance composition of Example 7 5.0 Ion-exchanged water 89 0.7 <Production Method> Carrageenan, propylene glycol and propylparaben were mixed and ion-exchanged water was added with stirring, and this was heated with gentle stirring until the temperature reached about 80 ° C. After that, the temperature is adjusted to about 65 ° C., the sedative composition for mental sedation is added to the mixture by a homogenizer at 3000 rpm while stirring to make a uniform phase, which is then poured into a predetermined container and naturally cooled to obtain a gel fragrance. It was

[Example 17] Liquid-type fragrance blending component blending amount (parts by mass) 95% ethanol 25.0 Surfactant 5.0 Psychologically relaxing fragrance composition of Example 7 3.0 Ion-exchanged water 67. 0 <Manufacturing Method> Each component except ion-exchanged water was mixed, and ion-exchanged water was added to the mixture while stirring gently to obtain a liquid type fragrance. Polyoxyethylene nonylphenyl ether EO-13 was used as the surfactant.

Example 18 Liquid type deodorant compounding ingredient compounding amount (parts by mass) Deodorant undiluted solution FS-500M (manufactured by Shiraimatsu Shinyaku Co., Ltd.) 5.0 95% ethanol 10.0 Surfactant 10.0 Acetylisoeugenol 10.0 Ion-exchanged water 65.0 <Manufacturing method> Each component other than ion-exchanged water was mixed, and ion-exchanged water was added with gentle stirring to obtain a deodorant (liquid type). Polyoxyethylene nonylphenyl ether EO-10 was used as the surfactant.

Example 19 Aerosol type deodorant compounding ingredient compounding amount (parts by mass) Deodorant stock solution FS-500M 5.0 95% ethanol 20.0 acetylisoeugenol 10.0 ion-exchanged water 40.0 liquefied petroleum Gas (4Kg / cm ² · 20 ° C) 25.0 <Manufacturing method> Components other than liquefied petroleum gas are mixed and stirred to homogenize, and a predetermined amount is put in an aerosol container and a valve is attached. After injection, a deodorant (aerosol type) was obtained.

[Example 20] Cream compounding ingredients Compounding amount (% by mass) Stearic acid 10.0 Stearyl alcohol 4.0 Butyl stearate 8.0 Stearic acid monoglycerin ester 2.0 Vitamin E acetate 0.5 Vitamin A palmitate 0.1 Macadamia nut oil 1.0 Tea seed oil 3.0 Glycerin 4.0 1,2-Pentanediol 3.0 Sodium hyaluronate 1.0 Potassium hydroxide 2.0 Magnesium ascorbyl phosphate 0.1 L-Arginine Hydrochloride 0.01 Trisodium edetate 0.05 Perfume composition for mental sedation of Example 9 0.4 Preservative Appropriate amount of purified water Residue <Production method> A cream was obtained by a conventional method.

[Example 21] Cream compounding ingredients Compounding amount (% by mass) Cetanol 4.0 Vaseline 7.0 Isopropyl myristate 8.0 Squalane 15.0 Stearic acid monoglycerin ester 2.2 POE (20) sorbitan monostea Rate 2.8 Vitamin E Nicotinate 2.0 Glycerin 10.0 Sodium Hyaluronate 0.02 Dipropylene Glycol 4.0 Sodium Pyrrolidone Carboxylate 1.0 The sedative perfume composition of Example 9 0.3 Disodium edetate 0.01 Antioxidant Proper amount Preservative Proper amount Purified water Residue <Production method> A cream was obtained by a conventional method.

[Example 22] Emulsion blending component blending amount (mass%) squalane 5.0 oleyl oleate 3.0 vaseline 2.0 sorbitan sesquioleate 0.8 POE (20) oleyl ether 1.2 evening primrose oil 0 .5 1,3-butylene glycol 4.5 ethanol 3.0 carboxyvinyl polymer 0.2 potassium hydroxide 0.1 L-arginine L-aspartate 0.01 edetate 0.05 psychosedation of Example 8 Perfume composition for preservative 0.3 Preservative Appropriate amount of purified water Residue <Production method> An emulsion was obtained by a conventional method.

[Example 23] Lotion formulation component content (mass%) cetanol 3.5 POE oleyl alcohol ether 2.0 2-ethylhexyl-p-dimethylaminobenzoate 0.18 1,3-butylene glycol 9.5 Sodium pyrrolidone carboxylic acid 0.5 Nicotinic acid amide 0.3 Glycerin 5.0 Cyringeraldehyde 0.05 (p-methylphenylacetaldehyde) Purified water Residue <Manufacturing method> Lotion was obtained by a conventional method.

[Example 24] Lotion formulation component content (mass%) Cetanol 3.5 POE oleyl alcohol ether 2.0 2-ethylhexyl-p-dimethylaminobenzoate 0.18 1,3-butylene glycol 9.5 Sodium pyrrolidone carboxylic acid 0.5 Nicotinic acid amide 0.3 Glycerin 5.0 Perfume composition for mental sedation of Example 5 0.05 Purified water Residue <Manufacturing method> A lotion was obtained by a conventional method.

[0076]

INDUSTRIAL APPLICABILITY According to the present invention, a new ingredient having a psychological sedative effect is found, and an external composition and miscellaneous goods containing a sedative fragrance composition containing the same are provided. .

[Brief description of drawings]

FIG. 1 shows the CN of the components contained in the present sedative composition.
It is drawing which shows a V measurement result.

─────────────────────────────────────────────────── ─── Continuation of front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) C11B 9/00 C11B 9/00 P S X A61K 7/00 A61K 7/00 C K 7/46 7/46 A61L 9/01 A61L 9/01 Q (72) Inventor Tatsushi Hotta 22-1, Hayabuchi, Tsuzuki-ku, Yokohama-shi, Kanagawa Prefecture Shiseido Research Center (Shin-Yokohama) (72) Inventor Sumie Taguchi Yokohama-shi, Kanagawa Prefecture 2-2-1 Hayabuchi, Tsuzuki-ku, Shiseido Research Center Co., Ltd. (Shin-Yokohama) (72) Inventor Masanori Yoshimura 2-2-1, Hayabuchi, Tsuzuki-ku, Tsuzuki-ku, Yokohama-shi, Kanagawa (72) Inventor Keiko Sakai 2-2-1, Hayabuchi, Tsuzuki-ku, Yokohama City, Kanagawa Prefecture Shiseido Research Center (Shin-Yokohama) F-term (reference) 4C080 A A03 BB03 CC01 HH03 HH06 KK06 LL06 LL07 LL09 MM12 MM13 MM15 MM16 4C083 AA122 AB032 AB312 AB352 AC012 AC022 AC072 AC522 AD322 AC53 AD622 AC542 AC2 AC2 AC04 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC2 AC4 AC2 AC4 AC2 BB21 BB41 BB48 CC02 CC04 CC05 CC25 EE06 4H059 BC01 DA09 EA40

Claims (4)

[Claims] 1. Terpynyl butyrate, γ-nonalactone, acetylisoeugenol, methyl anisate, terpineol, nerol, chrysanthenone, lyral, lilial, β-phenylethyl alcohol, γ-methylionone, iso-E-super, Z-3- Contains one or more components selected from the group consisting of hexenyl salicylate, p-methylphenylacetaldehyde, limonene, ocimene, helional, linalyl acetate, geranyl acetate, geraniol, hedion, linalool, citronellol, and γ-hexalactone. A fragrance composition for tranquilization. 2. An external composition containing the sedative fragrance composition according to claim 1. 3. The external use composition according to claim 2, wherein the product form of the external use composition is a cosmetic. 4. A miscellaneous goods containing the sedative fragrance composition according to claim 1.