JP2002310972A - Biosensor sheet, biosensor cartridge and biosensor distribution apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To rapidly and easily quantify a specific component in a physiological specimen with high accuracy using a biosensor. SOLUTION: The biosensor sheet is constituted of a base sheet having a plurality of the biosensors 4 acquiring the electrical data related to the specific component in the physiological specimen arranged thereon longitudinally so that the test ends of them are turned in the same direction and the cover film covering the surface of the base sheet and bonded to the sheet in a peelable manner so as to surround the respective biosensors to hermetically seal the biosensor parts. The biosensor cartridge 3 housing the biosensors is constituted to be mounted on the main body of the biosensor distribution apparatus 1 to make it possible to supply the biosensors 4 so that the test ends thereof precede.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a biosensor sheet, a biosensor cartridge, and a biosensor dispensing device for quickly and easily quantifying a specific component in a biological sample.

[0002]

2. Description of the Related Art In recent years, various biosensors utilizing a specific catalytic action of an enzyme have been developed and applied to a clinical field, and a biosensor capable of rapidly and accurately measuring a specific component in a biological sample has been developed. Sensors have been put to practical use.

[0003] Taking a glucose sensor as an example, the number of diabetic patients is remarkable today, so that a complicated procedure of centrifuging blood and separating plasma is conventionally required so that the blood glucose level can be easily measured and managed. In spite of the demand for a sensor capable of measuring whole blood, a proposal has been made in JP-A-61-294351. When this type of sensor is set in a dedicated measuring instrument, a predetermined voltage is supplied to the electrode system, the current flowing between the electrodes is measured, and the substrate concentration in the sample solution is calculated based on the current value, and the concentration is calculated. The value is shown on the display unit.

[0004] Japanese Patent Application Laid-Open No. Hei 8-262020 discloses a biosensor dispensing apparatus in which a biosensor cartridge in which a plurality of biosensors are set is loaded, and the biosensors are arranged one by one at a test position by operating a knob. Is described. With the development of such a biosensor dispensing device, when the sensor is attached to the measuring instrument body, it may be accidentally dropped, inserted in the opposite direction, or even measured while inserted in the opposite direction. The trouble which is likely to occur to users such as diabetic patients who have many patients has been improved.

The biosensor dispensing device 3 shown in FIGS.
0, a plurality of blood glucose sensors 34 are provided in a housing 33 including an upper case 31 and a lower case 32.
Is mounted in the sensor cavity 35. A data port connector (not shown) is provided at a rear portion 33a of the housing 33, through which data is input to electronic components on a printed wiring board in the housing 33, and a data port connector is provided. The data stored in the electric circuit of the above is taken out to a monitoring device or a computer.

Further, by moving a sliding actuator (not shown) arranged in the upper case 31 from the standby position to the test position, the sensor 34 is released from one of the sensor cavities 35 and The contacts are coupled to a microprocessor or other data processing circuit of a printed wiring board in the housing 33 at an electrode contact portion 37, and the test end of the sensor 34 projects from the test end 33b of the housing 33. .

Therefore, by inserting the test end of the sensor 34 into a blood sample, data of the blood sample can be obtained and processed. The processing data is displayed on the display screen 38 of the display unit or stored. When the sliding actuator is moved to the standby position after the test is completed, the used sensor 34 is discharged from the housing 33, and the biosensor cartridge 36 is rotated by the latch 39.
A new sensor 34 is released from the sensor cavity 35 and placed at the test position.

[0008]

However, in the above-described conventional biosensor device, the sensor 34 to which the biological sample such as blood is adhered must be discarded as it is after the test is completed. In addition, it is very inconvenient for the user because a disposal operation is required for each measurement. The present invention has been made to solve the above-described problem, and has as its object to dispose used biosensors in a sanitary and easy manner while being able to arrange biosensors one by one at a test position. .

[0009]

SUMMARY OF THE INVENTION In order to solve the above problems, the present invention provides a biosensor sheet in which a plurality of biosensors are arranged in tandem, a biosensor cartridge containing the biosensor sheet in a housing, and a sensor cartridge. The biosensor dispensing device that loads the biosensor can be used to send out the biosensor in the cartridge and set it to the measurement position, or to set the biosensor after the measurement is completed, with only a simple manual operation using the lever or dial of the dispensing device. The sensor can be collected in the cartridge. This makes it possible to easily and easily perform a plurality of biological value measurements.

[0010]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention according to claim 1 is a base in which a plurality of biosensors for acquiring electrical data relating to a specific component in a biological sample are arranged in tandem such that each test end faces in the same direction. A biosensor sheet comprising a sheet and a cover film that covers the surface of the base sheet and is peelably joined to the base sheet so as to surround each biosensor and individually seals each biosensor. By peeling off the cover film while sending out along the longitudinal direction so that the test end precedes, the biosensors can be sequentially arranged at the test position.

According to a second aspect of the present invention, in the biosensor sheet according to the first aspect, each of the biosensors has a rigidity in which a region near a test end thereof is self-supporting and has another region at one end opposite to the test end. It is characterized in that it is formed in a tongue shape on a flexible base sheet so as to be continuous, and when the biosensor sheet is sent out through some opening, the biosensor will protrude from the opening. In addition, the operation of spotting a biological sample on the test end can be easily performed. When the biosensor is formed integrally with the base sheet, it is possible to prevent individual biosensors from falling off.

According to a third aspect of the present invention, in the biosensor sheet according to the first aspect, the cover film is welded to the base sheet at an angle of 45 degrees or less with respect to the sending direction. In addition, the peeling resistance of the film when the biosensor sheet is peeled off with the delivery operation can be reduced.

According to a fourth aspect of the present invention, there is provided the biosensor sheet according to the first aspect, wherein one unit of the biosensor is alternately folded and laminated, and the storage form is constant. Therefore, it is possible to automatically stack even after the collection.

According to a fifth aspect of the present invention, there is provided a biosensor cartridge accommodating the biosensor sheet according to the first aspect and supplying the biosensors one unit at a time, wherein the sensor supply chamber and the sensor recovery chamber are separated by a partition. A case in which a sensor feed port opening in the sensor supply chamber and a sensor collection port opening in the sensor collection chamber are formed in parallel with each other,
The biosensor sheet is held between the sensor outlet and the sensor collection port so as to pass through the outside of the housing, and is sequentially fed along the longitudinal direction, so that unused biosensors are outside the sensor supply port. A sheet feeding unit that supplies and collects used biosensors into the housing from the sensor collection port, and a film peeling unit that is disposed in the housing near the sensor supply port and peels off the cover film of the biosensor sheet. The biosensor can be sequentially supplied and the used biosensor can be collected cleanly in the sensor collection chamber.

According to a sixth aspect of the present invention, in the biosensor cartridge according to the fifth aspect, the sheet feeding means passes through a supply roller for winding and feeding the biosensor sheet toward the sensor sending port, and a sensor collecting port. It has a winding roller for winding up the biosensor sheet, so that the biosensor can be easily sent out.

According to a seventh aspect of the present invention, there is provided the biosensor cartridge according to the fifth aspect, wherein the sheet feeding means is disposed downstream of the sensor collection port to sandwich the biosensor sheet, and is provided upstream of the sensor feeding port. It is characterized by having a drawing means for drawing in the biosensor sheet laminated on the downstream side and stacking it on the downstream side, so that the biosensor is drawn in while being folded, so it is designed without considering much the change in resistance applied to the drawing means it can.

According to an eighth aspect of the present invention, there is provided the biosensor cartridge according to the fifth aspect, further comprising a sealing member for sealing a sensor delivery port around the biosensor sheet. Can be prevented, and each biosensor can be maintained under a certain environment.

According to a ninth aspect of the present invention, there is provided the biosensor cartridge according to the fifth aspect, wherein a desiccant is provided in the housing, and the characteristic deterioration of the reagent substance used in each biosensor is achieved. Can be prevented and the performance can be maintained.

According to a tenth aspect of the present invention, there is provided the biosensor cartridge according to the fifth aspect, wherein a wall constituting a recovery path from the sensor sending port to the sensor recovery port is formed in a biosensor sheet in a tongue shape. The sensor is arranged outside the housing with a gap that can be bent downstream, and the used biosensor enters the recovery path while being folded with the biological sample attached part inside. In addition, the biological sample can be prevented from attaching to the measurer.

The present invention according to claim 11 is the biosensor cartridge according to claim 6, wherein a supply roller for feeding out the biosensor sheet, a film winding roller for winding the cover film, and a used biosensor sheet are wound. The take-up roller has a configuration in which the take-up roller has a slip clutch with respect to its rotation axis. Can absorb changes.

According to a twelfth aspect of the present invention, the biosensor cartridge according to the fifth aspect is mounted to drive the sending of the biosensor sheet via sheet feeding means, and the electric data acquired by each biosensor. A biosensor dispensing device that processes and outputs a processing result, wherein, on the outer periphery of the device main body, the biosensor cartridge is formed on a first side surface of a box in which a sensor outlet is formed and a second side adjacent thereto. The first side surface and the second side surface are housed such that the side surfaces are exposed, and the first side surface and the second side surface are provided with a concave portion arranged substantially flush with an outer side surface around the first side surface and the second side surface. It is possible to easily, easily, and continuously perform the measurement of the biometric data a plurality of times. Since the sensor outlet is located at the end of the apparatus main body, the operation of spotting the biological sample on the biosensor is easy.

According to a thirteenth aspect of the present invention, in the biosensor dispensing apparatus according to the twelfth aspect, the operating portion of the driving means connected to the sheet feeding means of the biosensor cartridge is provided on the first portion of the biosensor cartridge box. It is characterized by being arranged on the outer surface of the device body in the direction intersecting with the side surface and the second side surface, and the supply operation of the biosensor is hindered because the measurer does not cover the sensor supply port during operation. Absent. Further, it is possible to provide a means for displaying a measured value on both the outer surface of the device body in the direction along the first side surface of the case of the biosensor cartridge and the outer surface opposite thereto.

Hereinafter, embodiments of the present invention will be described with reference to the drawings. (Embodiment 1) FIG. 1 is an external perspective view of a biosensor dispensing device provided with a biosensor cartridge. FIG. 2 is (a) an exploded perspective view of a biosensor sheet, (b) a sectional view, and (c).
FIG. 3 is a plan view of the biosensor cartridge of FIG.
A sectional view, FIG. 4 is a sectional view of the vicinity of the supply unit of the biosensor dispensing apparatus of FIG.

This biosensor dispensing device 1 relates to blood glucose, and comprises a substantially rectangular box-shaped main body device 2 and a biosensor cartridge 3, and the biosensors 4 are sequentially arranged at test positions. And a function of collecting blood glucose concentration data through the biosensor 4.

The main unit 2 has a recess 5 for accommodating the biosensor cartridge 3 at one end (hereinafter, referred to as a front end 2a) along the longitudinal direction, and the other end (hereinafter, referred to as a front end 2a).
A display screen 6 of a liquid crystal display unit for displaying information on the biosensor cartridge 3 and information on an executed test is arranged on the upper surface near the rear end 2b). The concave portion 5 has a rectangular shape corresponding to the outer shape of the biosensor cartridge 3 and has an open front end and an upward opening, and the biosensor cartridge 3 housed in the concave portion 5 is located on the upper surface of the main body device 2 around the biosensor cartridge 3. It is configured to be flush with the front end face.

Two drive rollers 7 and 8 and an electrode arm 9 are provided upright on the upward bottom surface of the recess 5. A latch (not shown) provided on the inner surface of the recess 5 is provided on the upper surface of the main body device 2 near the recess 5.
A button 10 for engaging with the latch concave portion 3a is disposed, and on the outer surface in a direction intersecting the upper surface and the front end surface of the main body device 2, a rotating disk-shaped (or slidable) connected to the drive rollers 7, 8 is provided. ) The operation part of the operation actuator 11 is exposed.

The electrode arm 9 is connected to a microprocessor and other data processing circuits (not shown) formed on a printed wiring board inside the main body device 2. A manual button and a data port connector (not shown) provided on the rear end 2b are connected. Thereby, by inputting information to the data processing circuit from the manual button, the biosensor 4
Is generated, the information related to the test being performed is processed and stored, and the stored information is displayed on the display screen 6 or transmitted to an analysis device or a computer device outside the device via the data port connector. Output is possible.

As shown in FIG. 2, the biosensor 4 has an enzyme reaction part 4a containing an enzyme and an electrode contact part 4b. The biosensor 4 is made of a resin sheet 12 such as polyethylene terephthalate (PET). As the enzyme reaction part 4a and the electrode contact part 4b are arranged in this order along the longitudinal direction,
A plurality of them are formed in tandem. The resin sheet 12 is joined to a biosensor base 13 having substantially the same width on the lower surface, and forms a biosensor sheet 14. The upper surface of the biosensor sheet 14 is covered with a laminate film 15.

However, in the resin sheet 12, the region of the biosensor 4 extending from slightly forward of the enzyme reaction part 4a to the electrode contact part 4b is separated in a tongue shape by a U-shaped groove 4c whose front end side has an arc shape. , In a region other than the biosensor 4, and is tightly joined to the biosensor base 13. Therefore, the individual biosensors 4 do not fall off and advance toward the test end 3b of the biosensor cartridge 3 as the biosensor sheet 14 is fed forward.
From the spotting portion 4d at the front end of the biosensor 4 to the enzyme reaction portion 4a
Until then, a capillary tube for sucking a biological sample extends.

The laminating film 15 is attached to the biosensor sheet 14 by the spotting portion 4 of each biosensor 4.
a of 45 ° or less between the front of a and the rear of the electrode contact portion 4b.
The biosensors 4 are welded to the mold and continuously welded along the longitudinal edges of the laminate film 15 so that the biosensors 4 are isolated from each other and sealed. 1
5a is a welding line. For this reason, each of the enclosed biosensors 4 is kept in a dry state without the inflow and outflow of outside air, so that even if one biosensor 4 is opened, the other biosensors 4 are not affected.

As shown in FIG. 3, the inside of the box 16 of the biosensor cartridge 3 is divided into a sensor supply chamber 18 and a sensor recovery chamber 19 by a partition wall 17. Box 1
6, a sensor supply port 20 opening to the sensor supply chamber 18 along the partition 17 and a sensor collection port 21 opening to the sensor collection chamber 19 so as to be parallel to the sensor supply port 20 are formed. I have. A sensor guide wall 22 that covers the outer surface of the box 16 from the sensor supply port 20 to the sensor collection port 21 with a predetermined gap 22a is disposed outside the box 16.

The sensor supply chamber 18 has a sensor supply roller 23 around which the biosensor sheet 14 covered with the laminate film 15 is wound, a peel roller 24 for peeling the laminate film 15 from the biosensor sheet 14, and a peeling roller 24. A film take-up roller 25 for taking up the laminate film 15 and a transmission roller 2 for transmitting rotation of the sensor supply roller 23 to the film take-up roller 25
6 are arranged. The rotation shaft of the sensor supply roller 23 and the film winding roller 25 is engaged with a gear or the like to rotate. The winding portion sandwiches the slip clutch with respect to the rotation shaft, forming a slip pair. ing. In the vicinity of the sensor supply port 20, the sensor supply port 20 is provided.
Is disposed, and a desiccant 28 is disposed near the sensor supply roller 23.

In the sensor collection chamber 19, a sensor collection roller 29 for winding the biosensor sheet 14 in cooperation with the sensor supply roller 23 and the film winding roller 25, and the biosensor sheet 14 near the sensor collection port 21. A pair of guide rollers 30 for guiding to the sensor collection roller 29 is provided.

An opening (not shown) through which the electrode arm 9 of the main unit 2 can enter is formed near the sensor supply port 20, and the drive roller 7 of the main unit 2 is mounted on the sensor supply roller 23. It is designed to fit. In the initial state, the laminate film 15 is peeled off from the front end of the biosensor sheet 14 and the sensor collection roller 29 is removed.
The front end of the laminate film 15 is wound around the partition wall 1 by a peeling roller 24 near the electrode arm 9.
7 and is wound around the film take-up roller 25.

Hereinafter, the operation of the biosensor dispensing device 1 will be described. The biosensor cartridge 3 into the main unit 2
When the latch 1 (shown above) on the inner surface of the recess 5 is retracted by the button 10,
6 is set from above. As a result, the drive rollers 7, 8 on the bottom surface of the recess 5 and the electrode arm 9 enter the inside of the box 16 of the biosensor cartridge 3, and
8 fit into the sensor supply roller 23 and the sensor collection roller 29, respectively. When the box 16 reaches the bottom of the recess 5, the latch on the inner surface of the recess 5 automatically engages with the latch recess 3a of the box 16 by the action of a spring or the like (or by operating the button 10), and the biosensor The cartridge 3 is fixed.

At the time of the test, first, the operating actuator 11 is rotated (in the case of the slide type, the front end 2a of the main unit 2).
Side). As a result, the main unit 2 is set to the test mode, and the driving rollers 7 and 8 rotate by a predetermined amount, and the sensor supply chamber 18 which rotates accordingly.
The sensor supply roller 23 feeds the biosensor sheet 14 by one unit along the partition wall 17. The peeling roller 24 is turned and peeled off the laminated film 15 of the biosensor sheet 14 just before the electrode arm 9, and the exposed spotting portion 4 d of the biosensor 4 is tested through the sensor supply port 20. It protrudes from the end 3b. The peeled laminate film 15 is taken up by a film take-up roller 25 rotating with the sensor supply roller 23.

When the biosensor 4 is disposed at a test position protruding from the test end 3b by a predetermined length, the biosensor 4
Electrode contact portion 4b is in contact with the electrode arm 9 and is electrically coupled to the electronic circuit of the printed wiring board disposed in the main body device 2. At the same time, the display screen 6 of the liquid crystal display unit is activated to the display mode. The visual recognition of the display screen 6 from above is not hindered even when the operation actuator 11 is operated.

In this state, the biosensor cartridge 3
The blood accumulated in, for example, a punctured finger is brought into contact with the spotting portion 4d of the biosensor 4 protruding from the test end 3b (sensor supply port 20). As a result, the blood at the spotting portion 4d is sucked by capillary action and guided to the enzyme reaction portion 4a in a sufficient amount, and glucose, which is a test target component in the blood, chemically reacts with the reagent in the enzyme reaction portion 4a. . As a result, an electric signal corresponding to the blood glucose level is taken out to the electronic circuit of the printed wiring board in the main body device 2 through the electrode contact portion 4b and the electrode arm 9, and subjected to data processing.
The blood glucose level is displayed on the display screen 6.

When the test is completed and the acquisition of information and the transmission of data are completed, the operating actuator 11 is manually operated in the same manner as before the test. Thereby, the sensor supply roller 2
3. The sensor recovery roller 29 rotates and the biosensor sheet 14 is sent out. The used biosensor 4 that has protruded from the sensor supply port 20 is folded back downstream when being drawn into the gap 22a between the case 16 and the sensor guide wall 22, and the surface on which the blood adheres is removed. It is collected in the sensor collection chamber 19 while being arranged inside.

At this time, the biosensor sheet 14 is sent out by a constant amount by operating the operation actuator 11 (by a latch or the like not shown),
When the used biosensor 4 is collected in the sensor collection chamber 19 and the unused biosensor 4 remains in the sensor supply chamber 18, the feeding is temporarily stopped. Accordingly, main device 2 is turned off or in a standby state. When performing the test continuously, the operating actuator 11 may be operated until the unused biosensor 4 is arranged at the test position. The used biosensor 4 and the position of the biosensor 4 to be used next can be confirmed on the display screen 6.

Thus, the operating actuator 11
The biosensors 4 in the box 16 can be sequentially arranged at the test position only by manually operating the biosensor 4. At the same time, the used biosensors 4 can be collected in the box 16. Therefore, not only can a test be performed a plurality of times simply and easily, but also unnecessary worries about hygiene such as a user's dirty hands with blood can be reduced. When all the biosensors 4 of the biosensor sheet 14 have been used, the entire biosensor cartridge 2 may be discarded. Since the biosensor dispensing device itself can be configured to be relatively compact, it can be carried by a user.

FIG. 5 shows a biosensor cartridge 2 that does not use the above-described sensor supply roller 23 and sensor recovery roller 29. In the sensor cartridge 2, a biosensor sheet 14 in which one unit of the biosensor 4 is alternately folded and stacked is used, and a sensor retraction roller 31 that sandwiches and pulls the biosensor sheet 14 into the sensor collection chamber 19 is used. Opposing member 3 parallel to it
2 are arranged.

By operating the sensor pull-in roller 31, the used biosensor 4 is guided by the guide roller 30, pulled in one unit at a time, folded and stored, and a new biosensor 4 is newly stored in the sensor supply chamber 18. The biosensor 4 can be sent out one unit at a time.

In the biosensor sheet 14 described above, the spotting portion 4 d of each biosensor 4 is connected to the sensor supply port 20.
The U-shaped groove 4c is formed so as to protrude from the
Since the biological sample can be spotted as long as d is arranged outside the sensor supply port 20, the biosensor sheet 14 is
It may be a tape having no mold groove 4c. Also described as testing blood glucose,
It can also be configured for other biological samples that can be analyzed using reagents. In fact, it is applicable for any type of chemical fluid other than biological samples.

[0045]

As described above, according to the present invention, a biosensor sheet is formed by arranging a plurality of biosensors in tandem and hermetically sealing the biosensor sheet in a housing. Is loaded into the main unit with
The biosensor in the housing can be sent out and placed at the test position, test data can be collected, and the used biosensor can be collected in the housing. This makes it possible to easily and easily perform a plurality of biological value measurements, thereby reducing the burden of setting and disposing of the biosensor as compared with the related art.

[Brief description of the drawings]

FIG. 1 is an external perspective view of a biosensor dispensing apparatus including a biosensor cartridge according to an embodiment of the present invention.

2A is an exploded perspective view, FIG. 2B is a sectional view, and FIG. 2C is a plan view of a biosensor sheet stored in the biosensor cartridge of FIG.

FIG. 3 is a cross-sectional view of the biosensor cartridge taken along line AA of FIG. 1;

FIG. 4 is a cross-sectional view of a location near a supply unit of the biosensor dispensing device of FIG.

FIG. 5 is a cross-sectional view of another biosensor cartridge that can be loaded into the biosensor dispenser of FIG.

FIG. 6 is an external perspective view of a conventional biosensor dispensing device.

FIG. 7 is a perspective view showing the inside of the biosensor dispensing device of FIG. 6;

[Explanation of symbols]

 REFERENCE SIGNS LIST 1 biosensor dispensing device 2 main unit 3 biosensor cartridge 4 biosensor 4 c U-shaped groove 4 d spot application part 5 recess 11 actuation actuator 12 resin sheet 13 biosensor base 14 biosensor sheet 15 laminate film 15 a welding line 16 box 17 Partition wall 18 Sensor supply chamber 19 Sensor collection chamber 22 Sensor guide wall 23 Sensor supply roller 24 Peeling roller 25 Film take-up roller 27 Moisture-proof member 28 Desiccant 29 Sensor collection roller 31 Sensor pull-in roller 32 Opposing member

 ────────────────────────────────────────────────── ─── Continuing on the front page (72) Inventor Masashi Watanabe 1-8, Koshincho, Takamatsu-shi, Kagawa Prefecture Inside of Matsushita Hisashi Denshi Kogyo Co., Ltd. (72) Inventor Akiya Yada 1-8, Koshinmachi, Takamatsu-shi, Kagawa Prefecture Electronics Industry Co., Ltd.

Claims (13)

[Claims] 1. A base sheet in which a plurality of biosensors for acquiring electrical data relating to a specific component in a biological sample are arranged in tandem such that test ends face in the same direction. A biosensor sheet comprising: a cover film that is peelably joined to a base sheet so as to surround the biosensor and individually seals each biosensor. 2. Each of the biosensors is provided with a tongue on a flexible base sheet such that a region near the test end has self-supporting rigidity and is continuous with another region at one end opposite to the test end. The biosensor sheet according to claim 1 formed. 3. The cover film has a length of 4 with respect to the sending direction.
The biosensor sheet according to claim 1, wherein the biosensor sheet is welded to the base sheet at an angle of 5 degrees or less. 4. The biosensor sheet according to claim 1, wherein one unit of the biosensor is alternately folded and stacked. 5. A biosensor cartridge which stores the biosensor sheet according to claim 1 and supplies each biosensor one unit at a time, wherein the biosensor cartridge is divided into a sensor supply chamber and a sensor collection chamber by a partition.
A housing in which a sensor outlet opening in the sensor supply chamber and a sensor recovery opening opening in the sensor recovery chamber are formed in parallel to each other; and a housing between the sensor outlet and the sensor recovery opening for the biosensor sheet. And pass it along the longitudinal direction to supply unused biosensors to the outside of the sensor supply port and collect used biosensors into the housing from the sensor collection port. A biosensor cartridge comprising: sheet feeding means; and film peeling means disposed in a housing near the sensor supply port to peel off a cover film of a biosensor sheet. 6. A supply roller, wherein a sheet feeding means winds a biosensor sheet and feeds the sheet toward a sensor sending port;
6. The biosensor cartridge according to claim 5, further comprising a take-up roller for taking up the biosensor sheet passing through the sensor collection port. 7. A pull-in means which is arranged on the downstream side of the sensor collection port to sandwich the biosensor sheet, pulls in the biosensor sheet laminated on the upstream side of the sensor discharge port, and laminates the biosensor sheet on the downstream side. The biosensor cartridge according to claim 5, comprising: 8. The biosensor cartridge according to claim 5, further comprising a sealing member for sealing a sensor sending port around the biosensor sheet. 9. The biosensor cartridge according to claim 5, wherein the housing has a desiccant. 10. A wall forming a recovery path extending from a sensor sending port to a sensor recovery port is provided on the outside of the housing by providing a gap in which a tongue-shaped biosensor formed on a biosensor sheet can be bent downstream. The biosensor cartridge according to claim 5, which is arranged. 11. A supply roller for sending out a biosensor sheet, a film take-up roller for taking up a cover film, and a take-up roller for taking up a used biosensor sheet have a slip clutch with respect to its rotation axis. 7. The biosensor cartridge according to claim 6, wherein the cartridge is configured as follows. 12. A biosensor cartridge according to claim 5 is mounted to drive the sending of the biosensor sheet of the biosensor cartridge, to process the electrical data acquired by each biosensor, and to output a processing result. A biosensor dispensing device, wherein the biosensor cartridge is housed on an outer periphery of a device main body such that a first side surface of a box in which a sensor outlet is formed and a second side surface adjacent thereto are exposed. A biosensor dispensing device having a concave portion for arranging the first side surface and the second side surface substantially flush with an outer peripheral surface thereof. 13. The operating section of the driving means connected to the sheet feeding means of the biosensor cartridge is disposed on the outer surface of the apparatus main body in a direction intersecting with the first side surface and the second side surface of the box of the biosensor cartridge. The biosensor dispensing device according to claim 12.