JP2002306610A - Seal valve for medicinal solution injection and extraction hole - Google Patents

Abstract

PROBLEM TO BE SOLVED: To extract a medicinal solution and inject the same to a mixing and injection tube from a medicinal solution bottle only by a syringe without a needle. SOLUTION: The outside diameter D1 of a plug body 1 made by an elastic body formed by penetrating a straight line cut part 1a or a slit part 1f in the vertical direction in the central part is made larger than the bore diameter D2 of a medicinal solution injection and extraction hole 2a by interference, and the plug body 1 is pressed in the medicinal solution injection and extraction hole 2a, thereby generating clamping pressure in the cut part 1a or in the slit part 1f to perform sealing. The cut part 1a of slit part 1f of the plug body 1 is elastically deformed and opened by press-in of the syringe or the tip part 2 of a connector, and elastically restored to perform sealing by removal of the syringe or the tip part 3 of the connector.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to the use of an injection needle in a medical field or the like for extracting a drug solution from a drug bottle or a drug container (including a pouch) or for injecting a drug solution or the like into a co-infusion tube of an infusion circuit. TECHNICAL FIELD The present invention relates to a sealing device for an injection / extraction port for a drug solution or the like which enables a drug solution or the like to be directly injected and extracted from the tip of a syringe or a connector without using the same. In the present specification, the term “connector” refers to a device or an instrument used for an infusion circuit or a nutrition circuit in the medical field, and a pipe or the like used for supplying a drug solution or a liquid containing nutrients from a supply source. Means a connection device used for connecting the

[0002]

2. Description of the Related Art As shown in FIG. 27, a conventional bottle stopper of a chemical bottle is provided with a rubber stopper 22 which is press-fitted into a chemical solution injection / extraction port 21 of a bottle body 20, and which is covered with the rubber stopper 22 to form a bottle mouth flange. 2
3 and a cap 24 fixed to the cap 3. When extracting a chemical solution, the center of the cap 24 is peeled off or
An opening is provided in advance, and an injection needle 26 attached to the tip of the syringe 25 is pierced from the opening into the rubber stopper 22 to suck out the liquid medicine inside.

In a conventional co-injection tube, as shown in FIG. 28, a rubber stopper 32 is airtightly fitted into a branch tube portion 31 formed on the side of a tube main body 30 having a T-shape. The tube main body 30 is inserted and connected in the middle of an infusion circuit (for example, a dialysis circuit of an artificial kidney, an infusion circuit, etc.), and is connected to the rubber stopper 32 of the branch tube part 31 by the tip of the syringe 25. The injection needle 26 attached to the syringe is inserted and the syringe 2 is inserted.
5 is injected into the infusion circuit.

[0004]

A conventional sealing device used for a bottle stopper of a drug solution bottle or a drug solution injection / extraction port of a co-infusion tube includes:
It is necessary to pierce the rubber stopper with the needle and use it, which increases the cost for the use of the needle, and the used needle is sufficient for disposal to prevent contamination of pathogenic bacteria due to blood adhesion to the patient. There are issues that need attention,
There was also a problem of hospital-acquired infection due to such mistaken injection of used needles.

The present invention has been proposed in view of the above-mentioned conventional problems, and has as its object the purpose of extracting a drug solution from a drug solution bottle or the like and using a syringe alone without using a syringe needle and dispensing the solution to a co-infusion tube. An object of the present invention is to provide a sealing device for an injection / extraction port which can be injected, for example, a drug solution.

[0006]

In order to achieve the above object, a first aspect of the present invention is to provide a plug body made of an elastic body formed by vertically penetrating a straight cut portion or a slit portion at the center. The outer diameter is made larger than the inner diameter of the injection port for the drug solution or the like by the amount of the interference, and the stopper body is pressed into the injection port for the drug solution or the like to generate a clamping pressure in the cut portion or the slit portion. It is characterized by being sealed.

[0007] According to the above structure, the plug body is pressed into the injection port of the chemical solution or the like, thereby generating a stress around the plug body. A tightening pressure can be generated in the cut or slit to seal the cut or slit. Therefore, if the stopper body is press-fitted into the injection port of the drug solution bottle, the drug solution container or the co-infusion tube, it is possible to prevent the drug solution, blood or other liquid in the drug solution bottle, the drug solution container or the co-infusion tube from leaking to the outside. Can be. At the time of injecting and extracting a drug solution or the like, when the tip of the syringe or the connector is inserted toward the cut or slit, the elastic body around the cut or slit is elastically deformed and opened to inject and extract the drug or the like. Becomes possible. Therefore, according to the present invention, it is possible to inject / extract a liquid such as a drug solution from a drug solution bottle, a drug solution container, a co-infusion tube, etc. without using a syringe needle, and it is possible to reduce problems caused by the syringe needle. . When the tip of the syringe or the connector is withdrawn from the cut or slit, the elastic body around the cut or slit is elastically restored to seal the cut or slit.

A second aspect of the present invention is characterized in that a convex portion is formed on the outer peripheral portion of the plug body in a direction perpendicular to the longitudinal direction of the cut portion or the slit portion of the plug body according to the first aspect. I do.

According to the above construction, the sealing function can be further improved by further increasing the tightening pressure of the cut portion or the slit portion of the plug body by the convex portion.

[0010] Claim 3 of the present invention is directed to claim 1 or 2 above.
Wherein the slit portion of the plug body is formed as an elongated opening gap that penetrates in the vertical direction of the plug body when the plug body is formed.

According to the above configuration, the slit portion can be formed at the same time when the plug body is formed, and the step of forming the cut portion can be omitted.

A fourth aspect of the present invention is characterized in that the elongated opening gap of the slit portion of the third aspect is formed in parallel with the vertical direction of the plug body.

According to the above configuration, substantially the same sealing function can be exerted even when pressure is applied to the slit from above and below.

According to a fifth aspect of the present invention, the elongated opening gap of the slit portion of the third aspect is formed in a V-shaped cross section or an inverted V-shaped section in which the gap is gradually increased or decreased in the vertical direction of the plug body. Features.

According to the above construction, when the slit portion has a V-shaped cross section, the sealing function of the slit portion increases as the pressure from below the stopper body, that is, from the inside of the chemical bottle or the like, increases, so that the internal pressure resistance is reduced. Will be suitable for When the slit portion is an inverted V type, the sealing function of the slit portion increases as the pressure from the outside of the chemical bottle or the like increases, so that the slit portion is suitable for external pressure resistance.

According to a sixth aspect of the present invention, the cut portion or the slit portion of the stopper body according to any one of the first to fifth aspects is elastically deformed and opened by press-fitting the tip of the syringe or the connector. Alternatively, it is characterized in that the connector is elastically restored by pulling out the distal end portion of the connector and sealed.

According to the above configuration, at the time of injecting and extracting a drug solution or the like, when the tip of the syringe or the connector is inserted toward the cut or slit, the elastic body around the cut or slit is elastically deformed to open. When the tip of the syringe or the connector is pulled out, the elastic body around the cut or slit is elastically restored, and the cut or slit is sealed. Leakage of the liquid inside can be prevented.

A seventh aspect of the present invention is characterized in that the vertical thickness of the outer peripheral portion of the plug body according to any one of the first to sixth aspects is greater than the vertical thickness of the central portion. .

According to the above configuration, the tightening pressure of the cut portion or the slit portion can be increased.

According to an eighth aspect of the present invention, a uniform region having a uniform thickness in the vertical direction is formed at the center of the plug body according to the seventh aspect,
It is characterized in that a gradually increasing region in the vertical direction is formed in the outer peripheral portion.

According to the above configuration, the tightening pressure of the cut portion or the slit portion can be increased as in the case of the seventh aspect.

A ninth aspect of the present invention is characterized in that the thickness of the plug body according to the seventh aspect in the vertical direction is gradually increased from the central portion to the outer peripheral portion.

According to the above configuration, the tightening pressure of the cut portion or the slit portion can be increased similarly to the seventh or eighth aspect.

A tenth aspect of the present invention is characterized in that the plug body according to the seventh aspect is provided with a concave portion formed at both or one of the upper central portion and the lower central portion.

According to the above construction, the vertical thickness of the outer peripheral portion of the plug main body can be made larger than the vertical thickness of the central portion. Can be increased.

According to an eleventh aspect of the present invention, the concave portion at the lower central portion has a diameter larger than that of the central portion at the upper surface. Is characterized in that the corners are arc-shaped.

According to the above configuration, as the internal pressure of the chemical solution container or the like increases, the tightening pressure of the cut portion or the slit portion increases, and the function of preventing leakage of the filled liquid improves.
Then, by inserting the distal end of the syringe or connector into the cut or slit from the outside, the elastic body around the cut or slit is easily elastically deformed downward to open, and liquid injection or extraction is performed. it can. Further, when the pressing of the cut portion or the slit portion by the distal end portion of the syringe or the connector is released, the elastic body around the cut portion or the slit portion is elastically restored, so that the cut portion or the slit portion can be securely sealed. In particular, since the corner between the inner peripheral surface of the concave portion and the ceiling surface of the concave portion in the lower central portion has an arc shape, the repulsive force of the elastic body when the tip of the syringe or connector is inserted into the cut portion or the slit portion from above. It can be made large and the sealing performance can be improved.

A twelfth aspect of the present invention is characterized in that the inner surface of the recess at the center of the upper surface according to the tenth aspect is formed to have a slightly smaller diameter than the outer diameter of the tip of the syringe or connector.

According to the above configuration, when the tip of the syringe or the connector is inserted into the recess at the center of the upper surface of the stopper body, and further inserted into the cut or slit, the injection or extraction of the drug solution or the like is performed. It is possible to prevent a drug solution or the like from leaking from the concave portion, and to stably hold the syringe or the connector.

According to a thirteenth aspect of the present invention, the concave part at the center of the upper surface according to the tenth aspect is provided with an annular convex part having an inner diameter slightly smaller than the outer diameter of the tip part of the syringe or the connector on the inner surface. Features.

According to the above configuration, a function equivalent to that of the twelfth aspect is obtained.

A fourteenth aspect of the present invention is the first aspect.
3. Instead of the cut portion or the slit portion of the stopper body according to any one of 3, a conical hole penetrating vertically in the center of the stopper body is formed with its small diameter side on the lower surface side of the stopper body, and a chemical solution or the like is formed. The conical hole is sealed by a tightening pressure generated by press-fitting the stopper body into the injection port.

According to the above construction, when the tip of the syringe or the connector is inserted into the conical hole at the center of the upper surface of the stopper body, the tip of the syringe or the connector elastically deforms the elastic body around the conical hole. It is possible to open the conical hole by invading while making it possible to inject or extract a chemical solution or the like. At this time, since the elastic body around the conical hole is in close contact with the distal end of the syringe or the connector over the entire circumference, it is possible to prevent the leakage of the drug solution or the like from the conical hole. When the tip of the syringe or the connector is pulled out of the conical hole, the elastic body around the conical hole is elastically restored to seal the conical hole. Since the tightening pressure acting on the conical hole increases from the upper surface side to the lower surface side of the stopper main body, it facilitates insertion of the tip of the syringe or the connector, and conversely, against leakage of a drug solution or the like. As in the case of the check valve, the tightening pressure increases and the sealing function increases.

[0034] Claim 15 of the present invention is directed to Claims 1 to 1 above.
4. An air displacement pipe is provided in a part of the plug body according to any one of 4 above, so as to penetrate the plug body in a vertical direction.

According to the above construction, when extracting or injecting a liquid such as a drug solution from a drug solution bottle or a drug solution container or the like, air is introduced into or outflowed through the air replacement pipe into the inside of the drug solution or the like. Injection and extraction can be facilitated.

A sixteenth aspect of the present invention is characterized in that the air displacement pipe according to the fifteenth aspect is formed by filling a pipe material with a water-repellent substance that allows gas to pass therethrough but does not allow liquid to pass therethrough.

According to the above configuration, through the air displacement pipe,
Liquid inflow and outflow can be prevented, and only replacement inflow and outflow of air can be allowed.

A seventeenth aspect of the present invention is characterized in that the substance of the sixteenth aspect is provided with antibacterial properties.

According to the above configuration, through the air displacement pipe,
Bacteria can be prevented from entering with air from the outside.

[0040] Claim 18 of the present invention is directed to claims 15 to
17, a vertical through hole is formed in a part of the plug body according to any one of (17), and an air replacement pipe shorter than the through hole is inserted into the through hole while being biased toward the upper surface side of the plug body. When pressurized into the injection port for chemicals, etc., the periphery of the through hole below the lower end of the air displacement pipe is tightened in a lip shape by the tightening pressure of the elastic body, the repulsive force of this tightening pressure and the stress relaxing action. It is characterized in that it is configured to be a check valve against the outflow of etc.

According to the above construction, leakage of the liquid inside through the air displacement pipe can be prevented by the check valve action by the tightening pressure of the elastic body around the through hole below the insertion position of the air displacement pipe. However, only the invasion of air from the outside can be made possible.

Claim 19 of the present invention is directed to claims 15 to
18. Instead of the through hole for inserting the air displacement pipe described in any one of (18), a hole with a bottom having a bottom is provided, and the air displacement pipe is inserted and installed in this hole, and a cut penetrating vertically through the hole bottom portion. When the plug body is press-fitted into the injection port of a chemical solution or the like, a tightening pressure is generated in the cut portion or the small hole by the tightening pressure of the elastic body and the stress relaxing action. It is characterized by.

According to the above configuration, air can be circulated by the cut portion or the small hole below the air displacement pipe, and the flow of the liquid can be prevented.

According to a twentieth aspect of the present invention, an annular concave groove is provided around an upper surface of a plug body made of an elastic body formed by vertically penetrating a linear cut portion or slit portion at the center portion. An annular convex portion having a larger volume than the annular groove fitted to the annular groove is formed on the inner surface of the cap for fixing the liquid to the injection port for the chemical solution or the like, and the annular convex portion is pressed into the annular groove. By doing so, a tightening pressure is generated in the cut portion or the slit portion to seal the cut portion or the slit portion.

According to the above construction, by pressing the annular convex portion of the cap into the annular concave groove of the plug body, a stress is generated around the annular concave groove of the plug body, and the action of relieving the stress and the repulsive force are generated. As a result, a tightening pressure is generated in a cut portion or a slit portion at the center of the plug body to seal the cut portion or the slit portion. Therefore, a function equivalent to that of the first aspect can be obtained without depending on the tightening pressure from the outer peripheral portion of the plug body.

According to a twenty-first aspect of the present invention, there is provided a stopper or a slit portion of the stopper body according to any one of the first to twentieth aspects, wherein an annular retaining projection is provided at a further tip of the tip of the syringe or the connector. Alternatively, when inserted into the conical hole, the distal end of the syringe or the connector is configured to be locked by the retaining projection to prevent the syringe or the connector from falling off.

According to the above configuration, the insertion connection state of the tip of the syringe or the connector can be maintained for a long time and stably.

According to a twenty-second aspect of the present invention, there is provided a plug main body which is press-fitted into a chemical solution injection / extraction port with a predetermined interference, and is secured to the chemical solution injection / extraction port by a cap.
The upper surface of the plug body is a flat surface, a concave portion is formed on the lower surface side, and a cut portion, a slit portion, or a conical hole is formed at the center portion, and the upper surface of the plug body is On the flat surface, an annular convex portion that fits into the central hole of the cap is formed around the cut portion or slit portion at the center or around the conical hole, and the inside of this annular convex portion is flush with the outside. And the inner peripheral surface of the center hole of the cap is an inverted conical hole-shaped tapered surface, so that the tapered surface and the flat surface inside the annular convex portion on the upper surface of the plug body are formed so as to be smoothly continuous. It is characterized by having done.

According to the above construction, when a drug solution or the like accompanying the injection or extraction of the drug solution or the like by the syringe or the connector accumulates on the upper surface of the stopper body, it is wiped off with absorbent cotton or gauze, and absorbent cotton or gauze impregnated with a disinfectant such as alcohol. Disinfection can be easily performed.

According to a twenty-third aspect of the present invention, the inside of the annular convex portion on the upper surface of the plug body according to the twenty-second aspect is a flat surface higher than the outside or a convex arcuate surface.

According to the above configuration, it is possible to more easily perform the wiping of the chemical solution or the like collected on the upper surface of the stopper main body with absorbent cotton or gauze, and the disinfection with absorbent cotton or gauze impregnated with a disinfectant such as alcohol.

According to a twenty-fourth aspect of the present invention, the concave portion on the lower surface side of the plug body according to the twenty-second or twenty-third aspect has a substantially arc-shaped or tapered inclined surface at a corner between the inner peripheral surface and the ceiling surface. It is characterized by the following.

According to the above configuration, the compression repulsive force against the pushing of the tip of the syringe or the connector and the external pressure can be increased, and the pull-up resistance due to the internal pressure can be increased to prevent the coil from being turned up. The sealing performance of the part, the slit part or the conical hole can be improved.

According to a twenty-fifth aspect of the present invention, an insertion hole at the tip of a syringe or a connector is provided in the center of the upper surface of the stopper body made of the elastic body according to the first or second aspect so as to penetrate vertically. An annular groove was formed in the middle of the insertion hole, and two semi-disks were joined to the annular groove to form a single disk, and a valve membrane member having a cut or slit portion at the joint was airtightly fitted and held. It is characterized by the following.

According to the above configuration, the formation of the cut portion or the slit portion can be omitted, and two half disks can be used instead.

According to a twenty-sixth aspect of the present invention, an insertion hole at the tip of a syringe or connector is formed at the center of the upper surface of a stopper body made of an elastic body with a predetermined interference, and one end of the lower end of the insertion hole is formed. A flap valve that opens and closes the lower end opening of the insertion hole with the base as a fulcrum, and always closes the lower end opening with the elasticity and / or internal pressure of the base, In addition, a plastic inner cylinder is inserted through the insertion hole so as to be mounted, and a lower end of the inner cylinder is protruded from a lower end of the insertion hole to form a valve seat.

According to the above construction, the flap valve can be hermetically sealed by the elasticity and the internal pressure of the base of the flap valve, and the elastic restoring force is constantly applied to the base of the flap valve by the pressing force of the lower end of the inner cylinder. As a result, the sealing action of the flap valve can be improved. In addition, the flap valve is opened by inserting the tip of the syringe or the connector to inject / extract the chemical solution.

Claim 27 of the present invention is directed to Claims 1-2.
0, an insertion hole at the tip of the syringe or connector is formed at the center of the upper surface of the stopper body according to any one of (1) to (5), and a female screw groove is formed on the inner surface of the insertion hole or a plastic inner cylinder fitted and mounted in the insertion hole. The female screw groove and a male screw ridge formed at the tip of the syringe or the connector are screwed together so that they can be locked.

According to the above configuration, it is possible to prevent leakage of the drug solution from the insertion hole or the inner cylinder during the extraction or injection of the drug solution by inserting the distal end of the syringe or the connector into the insertion hole or the inner cylinder. At the same time, the insertion position of the tip of the syringe or the connector into the insertion hole or the inner cylinder can be stopped at an arbitrary position, and the connection state can be held at that position.

Claim 28 of the present invention is directed to claims 1-2.
0, an insertion hole for a tip of a syringe or a connector is formed at the center of the upper surface of the stopper main body, and one or more insertion holes or the inner surface of a plastic inner cylinder fitted and mounted in the insertion hole are formed. The annular locking portion is formed, and the annular locking portion and the annular locking portion formed at the distal end portion of the syringe or the connector can be locked and released.

According to the above configuration, it is possible to prevent leakage of the drug solution from the insertion hole or the inner cylinder during the extraction or injection of the drug solution by inserting the distal end of the syringe or the connector into the insertion hole or the inner cylinder. At the same time, the insertion position of the distal end of the syringe or the connector into the insertion hole or the inner cylinder can be stopped at the engagement position of the mutual annular engagement portion. Thus, the connection state between the stopper body and the tip of the syringe or the connector can be held by itself.

[0062]

Embodiments of the present invention will be described below with reference to the drawings.

The first embodiment is different from the first embodiment shown in FIGS.
As shown in (C), the outer diameter D ₁ of the stopper body 1 made of an elastic body such as rubber formed by vertically penetrating a straight cut portion 1 a at the center portion is changed to the chemical solution of the chemical bottle or the co-infusion tube 2. And a predetermined interference (D _{1) that is} larger than the inner diameter D ₂ of the injection / extraction port 2a.
-D ₂ ), the stopper body 1 is press-fitted into the injection port 2a for a chemical solution or the like, whereby a tightening pressure is generated in the cut portion 1a to seal the cut portion 1a.

The second embodiment is different from the first embodiment shown in FIGS.
As shown in (C), the protrusions 1b and 1b are formed on the outer peripheral portion of the plug body in a direction orthogonal to the longitudinal direction of the cut portion 1a of the plug body 1 to further increase the tightening pressure of the cut portion 1a. is there.

The plug body 1 has a cylindrical outer peripheral surface,
Concave portions 1c and 1d are provided at the center of the upper surface and the center of the lower surface. The inner diameter of the recess 1c on the upper surface side is slightly smaller than the outer diameter of the tip of the syringe or connector.

In FIG. 2, in order to facilitate the insertion of the tip of the syringe or connector into the recess 1c on the upper surface side, the recess 1 is used.
An R-shaped guide portion 1e is formed at the entrance of c.

The depth of the recess 1c on the upper surface side is shorter than the length of the tip of the syringe or the connector. Further, the bottom surface of the concave portion 1c on the upper surface side is a flat surface.

The recess 1d on the lower surface side is shown in FIGS.
Has the same inner diameter as the recess 1c on the upper surface side. 2B and 2C, the concave portion 1d on the lower surface side has a larger diameter than the concave portion 1c on the upper surface side, and a corner portion between the inner peripheral surface of the concave portion 1d on the lower surface side and the ceiling surface of the concave portion 1d. Are arc-shaped. The concave portion 1d on the lower surface side is originally formed to facilitate downward elastic deformation of the elastic body around the cut portion 1a at the center when the tip of the syringe or the connector is inserted. In normal times other than injection and extraction, the cut portion 1a preferably has a shape as shown in FIG. 2 in order to increase the sealing performance without opening unnecessarily. That is,
By making the shape of FIG. 2 as compared with the shape of FIG. 1, the resilient supporting force (compression repulsive force) against external pressure is increased by the elastic body of the arcuate portion at the corner, and the cut portion 1a
In addition to increasing the sealing performance of the cut part 1 and increasing the resistance to pulling up against the internal pressure (tensile resistance), the elastic body on both sides of the cut portion 1a tightens the cut portion 1a as the internal pressure increases. The sealing performance of the part 1a can be improved.

The plug body 1 is formed into the above-described shape using a mold. Then, the cut portion 1a is cut by using an appropriate cutter after the plug body 1 is molded. In that case,
The length of the cut portion 1a is substantially the same as the inner diameter of the concave portion 1c on the upper surface side.

The stopper body 1 of the present invention is obtained by inserting the tip of a syringe or connector into the recess 1c on the upper surface side.
The distal end portion pushes open the elastic body around the cut portion 1a while elastically deforming the elastic body in both downward directions to open the cut portion 1a. This enables injection and extraction of liquid. At this time, the distal end outer peripheral surface of the syringe or the connector is in close contact with the cut portion 1a and penetrates into the cut portion 1a, and is also in close contact with the internal peripheral surface of the concave portion 1c.
The liquid inside the medicine bottle or the like is prevented from leaking to the outside. When the tip of the syringe or the connector is pulled out, the elastic body around the cut portion 1a is elastically restored, the cut portion 1a is sealed, and leakage of the liquid is prevented.

The sealing function of the cut portion 1a will be described with reference to FIG. 1B. The inner diameter of the plug body is φ, the vertical thickness of the plug body is T, the external pressure is P, and the tightening pressure is P. _1, when the E stress factors external pressure P is transmitted to the clamping pressure P _1, can be expressed as ^{T / φ x = E E ×} P = P 1, by increasing the external pressure P or stress factor E, it is possible to increase the clamping pressure P _1.

FIGS. 3A and 3B are schematic illustrations of a pattern for increasing the tightening pressure by changing the external pressure receiving area of the plug body 1, and the shape of the plug body 1 is shown in FIG. (A)
(B) the vertical thickness of the outer peripheral portion of the plug body 1 increases the external pressure P and the stress factor E by changing greater than vertical thickness of the central portion can be increased tightening pressure P ₁ as. That is, in FIG. 3A, a region having a uniform thickness in the vertical direction is formed at the center of the plug main body 1, and a region having a gradually increasing thickness in the vertical direction is formed at the outer peripheral portion. FIG. 3B shows a case where the thickness in the vertical direction is gradually increased from the center of the plug body 1 toward the outer periphery. These relationships can be better in shown in FIG. 3 (A) of FIG. 3 than (B) to increase the clamping pressure P _1. The plug body 1 may have other shapes.

Next, FIGS. 4A, 4B, and 4C are schematic views showing examples of the shape pattern of the slit portion 1f formed in the plug body 1, and the cut portion 1a of the plug body 1 described above. Is
As shown in (A), (B), and (C) of FIG.
You may substitute for f. FIG. 4A shows a case where the slit portion 1f is formed as an opening gap parallel to the plug body 1 in the vertical direction. FIGS. 4B and 4C show the slit portion 1f.
Is formed in an inverted V-shaped cross section or a V-shaped cross section that gradually increases or decreases in the vertical direction of the plug body 1.

FIGS. 5A and 5B show a third embodiment of the present invention. In this embodiment, a plug main body 1 is formed with a slit portion 1f having an opening gap having a V-shaped cross section. I have. FIGS. 5C and 5D are partially enlarged explanatory views of the slit portion 1f. Before the external pressure is generated, the slit portion 1f, as shown in FIG. The outer diameter of the elastic body in the peripheral portion of D was _{1 1.} However, when an external pressure was generated by pressing the stopper body 1 into an injection / extraction port of a chemical solution or the like, as shown in FIG. When the diameter is reduced to D ₂ ′, the slit portion 1f is sealed. D ₁ 'above
And D ₂ ′ are proportional to the outer diameters D ₁ and D _{2 of the} entire plug body 1. In addition, the parallel slit part 1 shown in FIG.
f and the inverted V-shaped slit portion 1f shown in FIG. 4B also have the same sealing characteristics as those of FIGS. 5C and 5D. Further, as shown in FIG. 5 (B), by forming the corners between the inner peripheral surface and the ceiling surface of the concave portion 1d on the lower surface side in an arc shape, it is possible to push the distal end portion of the syringe or the connector and apply the external pressure. , The tension repulsive force against the internal pressure is increased to prevent rolling up, and the sealing performance of the slit portion 1f can be improved as the internal pressure increases.

FIGS. 6A and 6B show a fourth embodiment of the present invention. In this embodiment, instead of the cut portion 1a or the slit portion 1f, the center of the plug main body 1 is provided. A cross section and a bottom surface in a case where a conical hole 1g penetrating in the up-down direction is formed with the small diameter side formed on the lower surface side of the plug main body 1 are shown. FIG.
(C), (D) and (E) are partial enlarged explanatory views of the conical hole 1g. As shown in FIG. 6 (C), the conical hole 1g is formed slightly larger when the plug body 1 is formed. Then, annealing is performed to contract the small-diameter side of the conical hole 1g in a closed state as shown in FIG. 6D. In FIG. 6D, the outer diameter of the elastic body at the periphery of the conical hole 1g before the generation of the external pressure is D ₁ ′. When the external pressure is generated, the elastic body has a diameter D ₂ , as shown in FIG. It is manufactured so as to reduce the diameter to 'and seal the conical hole 1g. The outer diameters D ₁ ′ and D ₂ ′ of the elastic body around the conical hole 1 g correspond to the outer diameter D ₁ of the plug body _1.
And D ₂ . Further, as shown in FIG. 6 (A), by forming the corner between the inner peripheral surface and the ceiling surface of the concave portion 1d on the lower surface side in an arc shape, it is possible to push the distal end portion 3 of the syringe or the connector, and It is possible to increase the compression repulsive force against the external pressure, increase the pulling resistance due to the internal pressure, prevent the winding up, and increase the sealing performance of the conical hole 1g as the internal pressure increases.

FIGS. 7 (A), 7 (B) and 7 (C) show the operating state of the fourth embodiment until the tip 3 of the syringe or connector is inserted into the conical hole 1g of the stopper body 1 and withdrawn. (D), (E), and (F) of FIG. 7 show the states as viewed from the bottom. That is, in FIG. 7A, the stopper main body 1 receives a clamping pressure from the outer periphery toward the center portion by being pressed into an injection / extraction port such as a chemical bottle, and also receives the internal pressure of the chemical bottle or the like. Indicates a state in which the conical hole 1g is sealed. FIG. 7B
By inserting the distal end portion 3 of the syringe or connector into the concave portion 1c, the elastic body around the conical hole 1g is pushed out while being elastically deformed into the concave portion 1d on the lower surface side, so that the conical hole 1g is formed.
Are open, and a state in which injection and extraction of a drug solution or the like is possible is shown. In this state, the conical hole 1g is expanded and opened so as to be turned downward, and the elastic body around the conical hole 1g adheres to the outer peripheral surface of the distal end portion 3 of the syringe or the connector over the entire circumference, and the liquid Leakage can be reliably prevented. FIG.
(C) shows a state in which when the distal end portion 3 of the syringe or the connector is withdrawn, the elastic body around the conical hole 1g is elastically restored to seal the conical hole 1g, and thereafter, FIG. Return to the state of A). Also in this case, the concave portion 1d on the lower surface side has a larger diameter than the concave portion 1c on the upper surface side, and the corners of the inner peripheral surface and the ceiling surface are tapered inclined surfaces. The compression repulsive force against the indentation and the external pressure can be increased, and further, the pull-up resistance due to the internal pressure can be increased to prevent rolling up, and the sealing performance of the conical hole 1g can be enhanced as the internal pressure increases.

FIGS. 8A and 8B show a fourth embodiment of the present invention, in which the stopper 3 'is formed at the tip of the tip 3 of the syringe or connector to form an annular retaining projection 3'. This shows the state before and after inserting the distal end portion 3 of the syringe or connector into the hole 1g. In particular, as shown in FIG. 8 (B), the retaining projection 3 'is projected to the back side of the conical hole 1g. It is intended to stabilize the holding of the distal end portion 3 of the syringe or the connector and to lock the syringe or connector from coming off. This configuration is effective when it is necessary to connect the distal end portion 3 of the syringe or the connector for a long time to a drug solution injection / extraction port such as a drug solution bottle or a mixed injection tube.

FIG. 9A shows a fifth embodiment of the present invention. In this embodiment, an air replacement pipe 4 is installed in a part of a plug body 1 by vertically penetrating the same. I have. The air replacement pipe 4 is formed by filling a pipe material 4a with a water-repellent substance 4b that allows gas to pass therethrough but does not allow liquid to pass through. This substance 4
b is made of an appropriate fibrous material having a filter function, and is provided with water repellency and antibacterial properties.

In order to install the air displacement pipe 4, as shown in FIG. 9A, a through hole 1h is formed in a part of the plug body 1, and the air displacement pipe 4 shorter than the through hole 1h is used. Plug body 1
To the upper side of the device. In this way, when the plug body 1 is press-fitted into an injection / extraction port such as a chemical bottle, the air is replaced by the clamping pressure generated in the stopper body 1 and the repulsive force and stress relaxing action against the clamping pressure. As shown in FIG. 9 (B), the elastic body around the through hole 1h below the lower end of the pipe 4 is tightened in a lip shape and functions as a check valve 5 against outflow of a chemical solution or the like.

In place of the through hole 1h, as shown in FIG. 9C, a bottomed hole 1j having a bottom 1i as shown in FIG.
A cut portion 1k penetrating vertically through the bottom 1i of the hole 1j
Is formed with an appropriate cutter. When the air replacement pipe 4 is inserted into the hole 1j and the plug body 1 is pressed into an injection port such as a chemical bottle, a clamping pressure generated in the stopper body 1, a repulsive force against the clamping pressure and a stress relaxation action. And cut part 1k
Is sealed, so that leakage of a chemical solution or the like can be prevented. Instead of the cut portion 1k, a small hole may be formed with a needle-shaped punch. Further, the through hole 1h and the hole 1j are formed at the same time when the plug body 1 is formed.

FIGS. 10 (A) and 10 (B) show a sixth embodiment of the present invention, in which an annular concave groove 1n having a V-shaped cross section is provided around the upper surface of the plug main body 1, and corresponding thereto. An annular convex portion 6a having a circular cross section is formed on the inner surface of the cap 6, and these are shown in FIG.
By press-fitting as shown in FIG. 2B, a tightening pressure is generated in the plug body 1 to seal the cut portion 1a or the slit portion 1f. The annular groove 1n
Is formed outside the cut portion 1a or the slit portion 1f of the plug body 1. Further, the annular convex portion 6a is
The tightening pressure is generated by making the volume larger than that of the annular groove 1n. The shape of the annular groove 1n and the shape of the annular protrusion 6a may be other shapes than those shown in FIG. In this embodiment, it is not an essential requirement that the outer diameter of the stopper main body 1 be larger than the inner diameter of the injection port for the injection of a drug solution or the like.
As shown in FIG. 10, by forming a corner between the inner peripheral surface and the ceiling surface of the concave portion 1d on the lower surface side in an arc shape, the compression repulsive force against the pushing of the distal end portion of the syringe or the connector and the external pressure. And it is possible to increase the pulling resistance due to the internal pressure to prevent rolling up, and the sealing performance of the slit portion 1f can be increased as the internal pressure increases.

FIGS. 11A and 11B show a seventh embodiment of the present invention.
As shown in FIG. 11 (A), the liquid injection port 2a of the co-infusion tube 2 is press-fitted to the liquid injection port 2a with a predetermined interference, and is fixed to the liquid injection port 2a by the cap 6 so as not to come off. is there. As shown in FIG. 11B, the plug body 1 has a flat surface 1v on the upper surface, a concave portion 1d on the lower surface side, and a cut portion 1a or a slit portion 1f or a central portion at the center. One of the conical holes 1g is formed. On the flat surface 1v on the upper surface of the plug body 1, an annular convex portion 1u which fits into the central hole 6b of the cap 6 is formed around the central cut portion 1a or slit portion 1f or around the conical hole 1g. The inside of the annular convex portion 1u is a flat surface 1v 'so as to be flush with the outside. The inner peripheral surface of the center hole 6b of the cap 6 is an inverted conical hole-shaped tapered surface 6b '. The tapered surface 6b 'and the plug body 1
Is formed so as to be smoothly continuous with the flat surface 1v ′ inside the annular convex portion 1u on the upper surface of the substrate. This facilitates wiping with absorbent cotton or gauze when a chemical solution or the like accompanying injection and extraction of the chemical solution or the like by the syringe or connector accumulates on the upper surface of the plug main body 1 and disinfection with absorbent cotton or gauze impregnated with a disinfectant solution such as alcohol. ing.

FIGS. 12A and 12B show an eighth embodiment of the present invention.
Has substantially the same configuration as that of the seventh embodiment, and only different points will be described. As shown in FIG. 12 (B), the upper surface of the plug body 1 is a flat surface 1v, an annular step 1u 'is used instead of the annular protrusion 1u, and the inside of the annular step 1u' is an outer flat surface 1v. In this case, the plug body 1 is fixed to the chemical injection port 2a of the co-infusion tube 2 by a predetermined amount, as shown in FIG. By press-fitting with a margin and fixing with the cap 6, the central flat surface 1v "can be raised upward in a convex arc shape. This makes it easier to wipe off chemicals and the like on the upper surface of the plug main body 1 with absorbent cotton and gauze, and to disinfect with absorbent cotton and gauze impregnated with a disinfectant such as alcohol.

FIGS. 13A and 13B show a ninth embodiment of the present invention.
Also has a configuration substantially similar to that of the seventh embodiment, and only different points will be described. As shown in FIG. 13 (B), the upper surface of the plug body 1 is a flat surface 1v, an annular step 1u 'is used instead of the annular projection 1u, and the inside of the annular step 1u' is a convex arcuate surface 1w. It is what it was. When formed in this manner, as shown in FIG. 13 (A), when the stopper body 1 is press-fitted with a predetermined interference into the drug solution injection / extraction port 2 a of the co-infusion tube 2 and fixed with the cap 6. Thus, the central convex arc-shaped surface 1w can be further raised upward. This further facilitates wiping with absorbent cotton or gauze when a chemical solution or the like accumulates on the upper surface of the plug main body 1 and disinfection with absorbent cotton or gauze impregnated with a disinfecting solution such as alcohol.

In the seventh to ninth embodiments shown in FIGS. 11 to 13, the recess 1d on the lower surface side of the plug body 1 is originally
When the distal end of the syringe or the connector is inserted, the elastic body around the central cut portion 1a or the slit portion 1f or the conical hole 1g is formed so as to be easily elastically deformed downward. In order to improve the sealing performance without unnecessary opening during normal times other than injection and extraction, the corner between the inner peripheral surface and the ceiling surface of the concave portion 1d on the lower surface side is formed in an arc shape, and the tip of the syringe or connector is formed. The compression repulsive force against the indentation and the external pressure is increased, and the pull-up resistance due to the internal pressure is increased to prevent rolling up. As the internal pressure increases, the sealing performance of the slit portion 1f can be enhanced. Note that the seventh to ninth embodiments are not limited to the mixed injection tube, and can be applied to a drug solution bottle and other containers.

FIG. 14 shows a tenth embodiment of the present invention. The stopper body 1 is tightly fitted to the injection port 2a for a chemical solution or the like, and the upper flange 1
m is locked and fixed by polymerization, and the whole is made of an elastic body such as rubber. The concave portion 1c at the center of the upper surface is deepened to form an insertion hole 1c 'in the distal end portion 3 of the syringe or connector. The valve leaflet 1o is formed between the hole 1c 'and the recess 1d at the center of the lower surface, and the cut portion 1a is formed at the center of the valve leaflet 1o.

As shown in FIG. 15A, protrusions 1b and 1b are formed on the outer peripheral surface of the plug body 1 at a right angle to the longitudinal direction of the cut portion 1a in accordance with the formation position of the valve membrane portion 1o. The protrusion further increases the tightening pressure of the cut portion 1a. The outer diameter of the plug main body 1 is set to be larger than the inner diameter of the injection port 2a for the drug solution or the like shown in FIG.

FIG. 16A shows an eleventh embodiment of the present invention. In this embodiment, in order to increase the contact area of the cut portion 1a at the time of sealing, the shape of the cut portion 1a is changed to a valve membrane. The portion 1o has an uneven shape in the thickness direction.
FIG. 16B is an enlarged view illustrating the shape of the cut portion 1a as a mountain-shaped uneven shape indicated by a solid line and a wave-shaped uneven shape indicated by a chain line. The shape of the cut portion 1a is one-letter shape, cross shape,
Any shape such as a chevron, a waveform, and a concavo-convex shape may be used.

FIGS. 17A to 17E show a twelfth embodiment of the present invention.
FIGS. 1 to 16 show a 16th embodiment in which the valve membrane portion 1o of the plug body 1 is flat in the tenth and eleventh embodiments.
In the twelfth embodiment shown in FIG. 7A, a convex type (internal pressure resistant type) is used, in the thirteenth embodiment shown in FIG. 17B, a concave type (external pressure resistant type), and in the fourteenth embodiment shown in FIG. In the embodiment, the inner and outer biconvex type (inner and outer pressure resistant type), the fifteenth embodiment shown in FIG. 17D is an outer flat / inner convex type (inner pressure resistant type), and the sixteenth embodiment shown in FIG. Fig. 2 shows an example in which an inner flat / outer convex type (external pressure resistant type) is used. The internal pressure resistant type increases the sealing action of the cut portion 1a as the internal pressure increases, and the external pressure resistant type increases the cut portion 1a as the external pressure increases.
The sealing effect of a is increased. The shape of the valve membrane portion 1o may be an appropriate shape depending on the application to which the plug body 1 is applied.

FIGS. 18 (A), (B) and (C) are explanatory views of the opening operation of the valve membrane portion 1o of the twelfth embodiment.
When the distal end portion 3 of the syringe or connector is inserted into the insertion hole 1c ', the internal pressure in the insertion hole 1c' increases and the cut portion 1a starts to open as shown in FIG. When the part 3 is further inserted, as shown in FIG. 18 (C), the valve membrane part 1o is pushed by the tip part 3, and the cut part 1a is fully opened. In this state, injection or extraction of a chemical solution is performed. Thereafter, when the distal end portion 3 of the syringe or the connector is pulled out, the elastic restoring force of the valve membrane portion 1o and the insertion hole 1 are removed.
The cut portion 1a is sealed by the negative pressure generated in c '. The opening and closing operation of the valve membrane portion 1o is substantially the same in the tenth to sixteenth embodiments.

FIG. 19 shows a seventeenth embodiment of the present invention, in which lip portions 1a 'are provided on both the inner and outer surfaces of the mating surface of the cut portion 1a.
Is formed to increase the sealing force of the cut portion 1a in the valve membrane portion 1o.

FIGS. 20A and 20B are views for explaining the opening operation of the valve membrane 1o according to the eighteenth embodiment of the present invention. In the eighteenth embodiment, the inner surface of the insertion hole 1c 'of the plug body 1 is shown. 1 in
Or a plurality of (two in FIG. 20) annular locking portions 1p are formed, and a corresponding one of the annular locking portions 3a is provided at the distal end portion 3 of the syringe or the connector, and these are removed. Lockable and detachable. Then, in the first-stage locked state shown in FIG. 20A, the stopper main body 1 and the distal end portion 3 of the syringe or connector are kept in a state where the cut portion 1a is closed.
20A and 20B self-hold the connected state and prevent leakage of the chemical solution from the insertion hole 1c '. In the second-stage locked state shown in FIG. 20B, the plug is opened with the cut portion 1a opened. The main body 1 and the distal end portion 3 of the syringe or the connector maintain the connected state by themselves, so that the injection or extraction of the drug solution can be performed stably while preventing the leak of the drug solution from the insertion hole 1c '.

FIG. 21 shows a nineteenth embodiment of the present invention. In this embodiment, a plastic inner cylinder 7 is fitted to the inner surface of the insertion hole 1c 'of the stopper main body 1, and a syringe or connector is mounted. The smoothness and abrasion resistance of the insertion hole 1c 'into which the tip 3 is inserted are improved.

FIG. 22 shows a twentieth embodiment of the present invention. In this embodiment, a female screw groove 7a is provided on the inner surface of a plastic inner cylinder 7 fitted and mounted in the insertion hole 1c 'of the plug body 1. A male screw ridge 3b is formed at the tip 3 of the syringe or connector in correspondence with this, and by screwing them together, the connected state between the tip 3 of the syringe or connector and the plug body 1 can be held by itself. And With this configuration, the injection and extraction of the drug solution can be stably performed, and at the same time, the leak of the drug solution from the insertion hole 1c 'is prevented. When the plastic inner cylinder 7 is omitted, the female screw groove 7a is inserted into the insertion hole 1 of the plug body 1.
It is formed directly on the inner surface of c '.

FIGS. 23 (A), 23 (B), and 23 (C) show a twenty-first embodiment of the present invention. In this embodiment, the insertion hole 1c 'of the plug main body 1 is a through hole. An annular groove 1q is formed at the back of 1c ', and two semi-disks 8a, 8a made of an elastic material such as rubber are combined into the annular groove 1q to form a single disk-shaped airtight fitting. Thus, a valve leaflet 1o is obtained. In this embodiment, two semi-disks 8a, 8a
The cut 1a or the slit 1f is formed on the plug body 1 by making the joint of the cut 1a or the slit 1f.
The step for forming f can be omitted. In this case, the plastic inner cylinder 7 may or may not be provided.

FIGS. 24 (A), 24 (B) and 24 (C) show a twenty-second embodiment of the present invention. In this embodiment, a base is provided at one side of the lower end opening of the insertion hole 1c 'of the plug body 1. Are formed in a series. in this case,
As shown in FIG. 24B, a plastic inner cylinder 7 is fitted into the insertion hole 1c 'by projecting downward from the lower end opening of the insertion hole 1c'. Lower end opening 7
b is a valve seat of the flap valve 1r. With this configuration, the flap valve 1r is always provided with an elastic restoring force at the base thereof by the pressing force of the lower end of the inner cylinder 7, thereby improving the sealing action. An annular valve seat contact groove 1s that fits and contacts the lower end opening 7b of the inner cylinder 7 is formed on the upper surface of the flap valve 1r. This flap valve 1r is shown in FIG.
As shown in (2), the opening is made by inserting the distal end portion 3 of the syringe or the connector, and injection and extraction of the drug solution are performed.

FIG. 25 shows a twenty-third embodiment of the present invention. In this embodiment, a female screw groove 7a is formed on the inner surface of the inner cylinder 7 in the twenty-second embodiment, and a syringe or connector corresponding to this is formed. Male screw ridge 3b is provided on the outer peripheral surface of tip 3.
Are formed, and these are screwed together so that the tip 3 of the syringe or the connector is held in a connected state with respect to the plug body 1 by itself.

FIGS. 26A, 26B, and 26C show a twenty-fourth embodiment of the present invention.
The thickness of the flap valve 1r in the embodiment is reduced, and the operating characteristics of the flap valve 1r are sharpened while the sealing action by the internal pressure is secured.

While the embodiments of the present invention have been described above, the present invention is not limited only to these embodiments, but has the meaning and meaning of matters described in the claims. Embodiments having configurations within the scope are also intended to be included within the scope of the present invention. For example, the stopper body of each embodiment is used by being press-fitted into an injection port such as a medicinal solution bottle, a medicinal solution container, a co-infusion tube or the like. May be used. In each embodiment, the inner surface of the concave portion 1c at the center of the upper surface of the plug body 1 or the inner surface of the insertion hole 1c 'has a tapered surface shape adapted to the distal end portion 3 of the syringe or the connector, or an annular convex portion is formed on the inner surface. Formed into a headband shape,
The sealing performance between the distal end portion 3 of the syringe or the connector and the inner surface may be enhanced to increase the function of preventing leakage of the drug solution during injection / extraction of the drug solution. Further, the present invention can be applied to liquids in general other than chemical liquids. At this time, the injection and extraction of the liquid may be performed by using an adapter having a connection port similar to that of the syringe tip 3.

[0100]

According to the first aspect of the present invention, the plug body is pressed into the injection port of a chemical solution or the like to generate a stress around the plug body, and the action of relieving the stress and the repulsive force are provided. A tightening pressure can be generated at a cut or slit at the center of the plug body to seal the cut or slit. Therefore, if the stopper body is pressed into the injection port of the drug solution bottle, the drug solution container or the co-infusion tube, the drug solution bottle,
It is possible to prevent the drug solution, blood or other liquid in the drug solution container or the co-infusion tube from leaking to the outside. When the tip of the syringe or the connector is inserted toward the cut or slit at the time of injecting and extracting a drug solution or the like, the elastic body around the cut or slit is elastically deformed and opened to inject and extract the drug solution or the like. Becomes possible. Therefore, according to the present invention, it is possible to inject and extract a liquid such as a drug solution from a drug solution bottle, a drug solution container, a co-infusion tube, etc. without using a needle, and it is possible to reduce a problem caused by the needle. . When the tip of the syringe or the connector is withdrawn from the cut or slit, the elastic body around the cut or slit is elastically restored, and the cut or slit can be sealed.

According to the second aspect of the present invention, the sealing function can be further improved by further increasing the tightening pressure of the cut portion or the slit portion of the plug body by the convex portion.

According to the third aspect of the present invention, the slit portion can be formed at the same time when the plug body is molded, and the step of forming the cut portion can be omitted.

According to the fourth aspect of the present invention, substantially the same sealing function can be exerted even when pressure is applied to the slit from above and below.

According to the fifth aspect of the present invention, when the slit portion has a V-shaped cross section, the sealing function of the slit portion increases as the pressure from below the stopper body, that is, from the inside of the chemical solution bottle or the like increases. Suitable for internal pressure resistance. When the slit portion is an inverted V type, the sealing function of the slit portion increases as the pressure from the outside of the chemical bottle or the like increases, so that the slit portion is suitable for external pressure resistance.

According to the sixth aspect of the present invention, at the time of injecting and extracting a drug solution or the like, when the tip of the syringe or the connector is inserted toward the cut or slit, the elastic body around the cut or slit is elastically deformed. When it is deformed and opened, injection and extraction of drug solution etc. becomes possible, and when the tip of the syringe or connector is pulled out, the elastic body around the cut part or slit part elastically restores and seals the cut part or slit part, It is possible to prevent the liquid inside the medicine bottle or the like from leaking.

According to the seventh aspect of the present invention, the tightening pressure of the cut portion or the slit portion can be increased.

According to the eighth aspect of the present invention, similarly to the seventh aspect, the tightening pressure of the cut portion or the slit portion can be increased.

According to the ninth aspect of the present invention, the tightening pressure of the cut portion or the slit portion can be increased as in the case of the seventh or eighth aspect.

According to the tenth aspect of the present invention, the vertical thickness of the outer peripheral portion of the plug main body can be made larger than the vertical thickness of the central portion. Can be increased.

According to the eleventh aspect of the present invention, as the internal pressure of the chemical solution container or the like increases, the tightening pressure of the cut portion or the slit portion increases, and the function of preventing leakage of the filled liquid improves. And by inserting the tip of the syringe or connector from outside into the cut or slit,
The elastic body around the cut portion or the slit portion is easily elastically deformed downward to open, and the liquid can be injected or extracted. Further, when the pressing of the cut portion or the slit portion by the distal end portion of the syringe or the connector is released, the elastic body around the cut portion or the slit portion is elastically restored, so that the cut portion or the slit portion can be securely sealed.

According to the twelfth aspect of the present invention, the tip of the syringe or the connector is inserted into the recess at the center of the upper surface of the stopper body, and further inserted into the cut or slit to inject or extract a drug solution or the like. When performing the above, it is possible to prevent the leakage of the drug solution or the like from the concave portion, and it is possible to stably hold the syringe or the connector.

According to the thirteenth aspect of the present invention, a function equivalent to that of the twelfth aspect is obtained.

According to the fourteenth aspect of the present invention, when the distal end of the syringe or the connector is inserted into the conical hole at the center of the upper surface of the stopper body, the distal end of the syringe or the connector becomes elastic around the conical hole. The conical hole can be opened by invading while deforming the body elastically, and injection or extraction of a chemical solution or the like can be performed. At this time, since the elastic body around the conical hole is in close contact with the distal end of the syringe or the connector over the entire circumference, it is possible to prevent the leakage of the drug solution or the like from the conical hole. When the tip of the syringe or the connector is pulled out of the conical hole, the elastic body around the conical hole is elastically restored to seal the conical hole. Since the tightening pressure acting on the conical hole is increased from the upper surface side to the lower surface side of the stopper body, it facilitates insertion of the tip of the syringe or the connector, and conversely,
As with the check valve, the tightening pressure increases against leakage of chemicals and the like, and the sealing function increases.

According to the fifteenth aspect of the present invention, when extracting or injecting a liquid such as a drug solution from a drug solution bottle, a drug solution container, or the like, the replacement inflow or outflow of air into the interior through the air replacement pipe is performed. In addition, it is possible to smoothly inject and extract a drug solution and the like.

According to the sixteenth aspect of the present invention, the inflow and outflow of liquid can be prevented through the air replacement pipe, and only the replacement inflow and outflow of air can be made possible.

According to the seventeenth aspect of the present invention, it is possible to prevent bacteria from entering from the outside together with air through the air replacement pipe.

According to the eighteenth aspect of the present invention, leakage of the liquid inside through the air displacement pipe is prevented by the check valve action by the tightening pressure of the elastic body around the through hole below the insertion position of the air displacement pipe. And only air intrusion from the outside can be allowed.

According to the nineteenth aspect of the present invention, the cut portion or the small hole below the air replacement pipe enables air to flow and prevents liquid from flowing.

According to the twentieth aspect of the present invention, by pressing the annular convex portion of the cap into the annular concave groove of the plug body,
A stress is generated around the annular concave groove of the plug main body, and a tightening pressure is generated at a cut portion or a slit portion of the center portion of the plug main body by an action of relieving the stress and a repulsive force, so that the cut portion or the slit portion is formed. Can be sealed. Therefore, the above-mentioned claim 1 does not depend on the tightening pressure from the outer peripheral portion of the plug body.
A function equivalent to that of the invention is obtained.

According to the twenty-first aspect of the present invention, the insertion connection state of the tip of the syringe or the connector can be maintained for a long time and stably.

According to the twenty-second aspect of the present invention, when a drug solution or the like accompanying injection and extraction of a drug solution or the like by a syringe or a connector accumulates on the upper surface of the stopper body, it is wiped with absorbent cotton or gauze and impregnated with a disinfecting solution such as alcohol. Disinfection with absorbent cotton, gauze, or the like can be easily performed.

According to the twenty-third aspect of the present invention, it is possible to more easily perform the wiping of the chemical solution or the like collected on the upper surface of the stopper main body with absorbent cotton or gauze, and the disinfection with absorbent cotton or gauze impregnated with a disinfectant such as alcohol. it can.

According to the twenty-fourth aspect of the present invention, it is possible to increase the compression repulsive force against the pushing and the external pressure of the distal end portion of the syringe or the connector, and also to increase the pulling resistance force due to the internal pressure to prevent the syringe from being rolled up. The higher the height, the higher the sealing performance of the cut portion, the slit portion, or the conical hole.

According to the twenty-fifth aspect of the present invention, the formation of the cut portion or the slit portion can be omitted, and two half disks can be used instead.

According to the twenty-sixth aspect of the present invention, the flap valve can be hermetically sealed by the elasticity and the internal pressure of the base of the flap valve, and elastically restored to the base of the flap valve by the pressing force of the lower end of the inner cylinder. Force can be constantly applied to improve the sealing action of the flap valve. In addition, the flap valve is opened by inserting the tip of the syringe or the connector to inject / extract the chemical solution.

According to the twenty-seventh aspect of the present invention, while extracting or injecting a drug solution by inserting the distal end of a syringe or connector into the insertion hole or the inner cylinder, leakage of the drug solution from the insertion hole or the inner cylinder is prevented. In addition, the insertion position of the tip of the syringe or the connector into the insertion hole or the inner cylinder can be stopped at an arbitrary position, and the connected state can be held at that position.

According to claim 28 of the present invention, while extracting or injecting a drug solution by inserting the tip of a syringe or connector into the insertion hole or the inner cylinder, leakage of the drug solution from the insertion hole or the inner cylinder is prevented. And the insertion position of the distal end of the syringe or connector into the insertion hole or the inner cylinder can be stopped at the engagement position of the mutual annular engagement portion, and therefore, the opening position of the cut portion or the slit portion The connection between the plug body and the distal end of the syringe or connector can be self-held at the and sealing position.

[Brief description of the drawings]

FIG. 1A is a plan view of a plug main body according to a first embodiment,
(B) is a longitudinal sectional view, and (C) is a principal part longitudinal sectional view in which a plug body is press-fitted into a co-infusion tube and fixed with a cap.

FIG. 2A is a plan view of a stopper main body according to a second embodiment,
(B) is a longitudinal sectional view, and (C) is a principal part longitudinal sectional view in which a plug body is press-fitted into a co-infusion tube and fixed with a cap.

FIGS. 3A and 3B are schematic explanatory diagrams of patterns in which a tightening pressure is increased by changing an external pressure receiving area of a plug main body.

FIGS. 4A, 4B, and 4C are schematic diagrams showing examples of a shape pattern of a slit formed in a plug body.

FIGS. 5A and 5B are a plan view and a longitudinal sectional view of a plug body according to a third embodiment, and FIGS. 5C and 5D are V-shaped slit sections before and after the generation of a tightening pressure in the third embodiment. FIG.

6 (A) and 6 (B) are a plan view and a longitudinal sectional view of a stopper body of a fourth embodiment, FIG. 6 (C) is an enlarged longitudinal sectional view of a conical hole portion in a state at the time of molding, and FIG. 6 (D) is annealing. FIG. 4E is a longitudinal sectional view of the conical hole portion in a contracted state after the compression, and FIG. 4E is an enlarged longitudinal sectional view of the conical hole portion when tightening pressure is applied.

FIGS. 7A, 7B, and 7C are views for explaining the opening operation of the conical hole portion by the tip of the syringe or the connector in the fourth embodiment, and FIGS. 7D, 7E, and 7F are bottom views in each case. FIG.

FIGS. 8A and 8B are explanatory views of the operation of the fourth embodiment before and after inserting a syringe or connector having a ring-shaped retaining projection at the distal end into a conical hole of a plug body. FIG.

9A is a longitudinal sectional view of a plug body according to a fifth embodiment in a state before a tightening pressure is generated, FIG. 9B is a longitudinal sectional view of the plug body in a state when a tightening pressure is applied, and FIG. FIG. 13 is a longitudinal sectional view of a modified example in which an air displacement pipe is installed in the plug body of the fifth embodiment.

FIGS. 10A and 10B are longitudinal sectional views showing states before and after fitting of a cap and a plug body in a sixth embodiment.

FIG. 11A is a vertical side view of the assembled state of the stopper body of the present invention in a mixed injection tube according to the seventh embodiment, and FIG. 11B is a longitudinal side view of the stopper body alone.

FIG. 12 (A) is a vertical side view of an assembled state of a stopper body of the present invention in a mixed injection tube according to an eighth embodiment, and FIG. 12 (B) is a longitudinal sectional side view of the stopper body alone.

FIG. 13 (A) is a longitudinal side view of the ninth embodiment of the present invention in which the plug body of the present invention is assembled to a co-infusion tube, and FIG. 13 (B) is a longitudinal side view of the stopper body alone.

FIG. 14 is a longitudinal sectional view of a main part of a tenth embodiment.

FIG. 15 (A) is a bottom view of the plug body of the tenth embodiment,
(B) is a cross-sectional plan view of an injection / extraction port for a drug solution or the like.

FIG. 16A is a longitudinal sectional view of a main part of the eleventh embodiment,
(B) is an enlarged view of a cut portion.

FIGS. 17A to 17E are longitudinal sectional views of main parts of the twelfth to sixteenth embodiments.

FIGS. 18 (A), (B), and (C) are explanatory views of an opening operation of a valve membrane portion according to a twelfth embodiment.

FIG. 19 is a longitudinal sectional view of an essential part of a seventeenth embodiment.

FIGS. 20A and 20B are longitudinal cross-sectional views of a relevant part showing states before and after an opening operation of a valve membrane according to an eighteenth embodiment.

FIG. 21 is a longitudinal sectional view of a main part of a nineteenth embodiment.

FIG. 22 is a longitudinal sectional view of a main part of a twentieth embodiment.

FIG. 23A is a longitudinal sectional view of a main part of a twenty-first embodiment,
(B) is a longitudinal sectional view of a main part in a state when the valve is opened, and (C) is an exploded perspective view of a valve leaflet.

24A is a longitudinal sectional view of a main part of the twenty-second embodiment in a state where a stopper body is used alone, FIG. 24B is a longitudinal sectional view of a principal part in a state where a plastic inner cylinder is attached to the stopper body, and FIG. ) Is a longitudinal sectional view of a main part in a state when the valve is opened.

FIG. 25 is a longitudinal sectional view of an essential part of a twenty-third embodiment.

26A is a longitudinal sectional view of a main part of a twenty-fourth embodiment in a state where a stopper body is used alone, FIG. 26B is a principal part longitudinal cross-sectional view of a state where a plastic inner cylinder is mounted on the stopper body, and FIG. ) Is a longitudinal sectional view of a main part in a state when the valve is opened.

FIG. 27 is a sectional view for explaining a bottle stopper of a conventional chemical solution bottle.

FIG. 28 is an explanatory sectional view of a conventional co-infusion tube.

[Explanation of symbols]

 Reference Signs List 1 stopper body 1a cut portion 1a 'lip portion 1b convex portion 1c upper surface side concave portion 1c' insertion hole 1d lower surface side concave portion 1e annular convex portion 1f slit portion 1g conical hole 1h through hole 1i bottom 1j hole 1k cut portion 1m upper flange Part 1n annular concave groove 1o valve leaflet part 1p annular locking part 1q annular groove 1r flap valve 1s valve seat contact groove 1u annular convex part 1u 'annular step part 1v flat surface 1v' flat surface 1v "flat surface 1w convex circular arc surface 2 Chemical liquid bottle or co-infusion tube 2a Chemical liquid injection / extraction port 2b Flange projection 3 Tip of syringe or connector 3 'Annular retaining projection 3a Annular locking part 3b Male screw ridge 4 Air replacement pipe 4a Pipe material 4b Water repellent Substance 5 Check valve 6 Cap 6a Annular projection 6b Center hole 6b 'Tapered surface 7 Inner cylinder 7a Female thread groove 7b Lower end opening 8a Semi-disc

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[Procedure amendment]

[Submission date] August 1, 2001 (2001.8.1)

[Procedure amendment 1]

[Document name to be amended] Statement

[Correction target item name] Name of invention

[Correction method] Change

[Correction contents]

[Title of the Invention] Sealing valve for injection port of chemical liquid etc.

[Procedure amendment 2]

[Document name to be amended] Statement

[Correction target item name] Claims

[Correction method] Change

[Correction contents]

[Claims]

[Procedure amendment 3]

[Document name to be amended] Statement

[Correction target item name] 0001

[Correction method] Change

[Correction contents]

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to the use of an injection needle in a medical field or the like for extracting a drug solution from a drug bottle or a drug container (including a pouch) or for injecting a drug solution or the like into a co-infusion tube of an infusion circuit. TECHNICAL FIELD The present invention relates to a seal valve for a drug solution or the like injection / extraction port which allows a drug solution or the like to be directly injected and extracted from the tip of a syringe or a connector without using the same. In the present specification, the term “connector” refers to a device or an instrument used for an infusion circuit or a nutrition circuit in the medical field, and a pipe or the like used for supplying a drug solution or a liquid containing nutrients from a supply source. Means a connection device used for connecting the

[Procedure amendment 4]

[Document name to be amended] Statement

[Correction target item name] 0004

[Correction method] Change

[Correction contents]

[0004]

A conventional seal valve used for a bottle stopper of a drug solution bottle or a drug solution injection / extraction port of a co-infusion tube is:
It is necessary to pierce the rubber stopper with the needle and use it, which increases the cost for the use of the needle, and the used needle is sufficient for disposal to prevent contamination of pathogenic bacteria due to blood adhesion to the patient. There are issues that need attention,
There was also a problem of hospital-acquired infection due to such mistaken injection of used needles.

[Procedure amendment 5]

[Document name to be amended] Statement

[Correction target item name] 0005

[Correction method] Change

[Correction contents]

[0005] The present invention has been proposed in view of the above-mentioned problems, and it is an object of the present invention to extract a drug solution from a drug solution bottle or the like by using only a syringe without using an injection needle and to supply the solution to a co-infusion tube. An object of the present invention is to provide a seal valve for an injection / extraction port for an injection port of a drug solution or the like which can be injected.

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI theme coat ゛ (reference) // F16K 24/00 F16L 37/28 F (72) Inventor Kihito Okui 1-chome Nishijuku, Minoh-shi, Osaka No. 21 No.4 Fukai Industrial Co., Ltd. F-term (reference) 3H017 AA05 AA09 3H055 GG21 HH00 JJ10 3J106 AB01 BA01 BA03 BB01 BB04 BC12 BD01 BE29 CA01 GA01 GA04 GA12 GA40 GB01 4C066 AA09 BB01 CC01 DD06 GG03 JJ02

Claims (28)

[Claims] 1. An outer diameter of a stopper body made of an elastic body formed by vertically penetrating a straight cut portion or a slit portion in a center portion, the outer diameter of the stopper body being larger than the inner diameter of an injection port for a drug solution or the like by a margin. A sealing device for an injection port for a drug solution or the like, characterized in that the plug body is pressed into an injection port for a drug solution or the like to generate a tightening pressure in the cut portion or the slit portion to seal. . 2. The injection port according to claim 1, wherein a convex portion is formed on an outer peripheral portion of the plug main body in a direction orthogonal to a longitudinal direction of the cut portion or the slit portion of the plug main body. For sealing device. 3. The injection port for chemicals or the like according to claim 1, wherein the slit portion of the plug body according to claim 1 or 2 is formed as an elongated opening gap penetrating in a vertical direction of the plug body when the plug body is formed. For sealing device. 4. A sealing device for an injection port for a drug solution or the like, wherein the elongated opening gap of the slit portion according to claim 3 is formed in parallel with the vertical direction of the plug body. 5. The injection of a drug solution or the like, wherein the elongated opening gap of the slit portion according to claim 3 is formed in a V-shaped cross section or an inverted V-shaped cross section in which the gap is gradually increased or decreased in the vertical direction of the plug body. Extraction port sealing device. 6. The cut portion or the slit portion of the stopper body is elastically deformed and opened by press-fitting the tip of the syringe or the connector, and is elastically restored by withdrawing the tip of the syringe or the connector to seal. The sealing device for an injection port for a drug solution or the like according to claim 1, wherein the sealing device is formed. 7. The injection port according to claim 1, wherein a vertical thickness of an outer peripheral portion of the stopper main body is made larger than a vertical thickness of a central portion thereof. Sealing device. 8. The injection of a chemical solution or the like according to claim 7, wherein a region having a uniform thickness in the vertical direction is formed in the center of the plug body, and a region having a gradually increasing thickness in the vertical direction is formed in the outer peripheral portion. Extraction port sealing device. 9. The sealing device for an injection port for chemical liquids or the like according to claim 7, wherein the thickness in the vertical direction is gradually increased from the center to the outer periphery of the plug main body. 10. The hermetically sealing device according to claim 7, wherein a concave portion is formed in at least one of a central portion of an upper surface and a central portion of a lower surface of the plug body. 11. The concave portion at the lower central portion according to claim 10 has a larger diameter than the concave portion at the upper central portion, and the corner between the inner peripheral surface of the concave portion at the lower central portion and the ceiling surface of the concave portion has an arc shape. A sealing device for an injection / extraction port for a drug solution or the like, characterized in that: 12. The sealing device for an injection port for a drug solution or the like according to claim 10, wherein the inner surface of the concave portion at the center of the upper surface is an insertion hole slightly smaller in diameter than the outer diameter of the tip of the syringe or the connector. 13. The injection of a drug solution or the like, characterized in that the recess at the center of the upper surface according to claim 10 is provided with an annular projection having an inner diameter slightly smaller than the outer diameter of the tip of the syringe or connector on the inner surface. Extraction port sealing device. 14. A conical hole penetrating vertically through a center portion of the plug body in place of the cut portion or the slit portion of the plug body according to any one of claims 1 to 13, and a small diameter side of the conical hole is formed in the plug body. A sealing device for a drug solution or the like injection / extraction port, which is formed on the lower surface side, and wherein the conical hole is sealed by a tightening pressure generated by press-fitting the plug body into the injection / extraction port for a drug solution or the like. 15. An injection and extraction of a chemical solution or the like, characterized in that an air replacement tube is installed in a part of the plug body according to any one of the above-mentioned items 1 through 14 so as to penetrate in a vertical direction of the plug body. Mouth sealing device. 16. The sealing device for an injection / extraction port for a chemical solution or the like, characterized in that the air replacement pipe according to claim 15 is formed by filling a pipe material with a water-repellent substance that allows gas to pass through but does not allow liquid to pass through. . 17. A sealing device for an injection port for a drug solution or the like, characterized in that the substance according to claim 16 is provided with antibacterial properties. 18. A vertical through-hole is formed in a part of the plug main body, and an air replacement pipe shorter than the through-hole is inserted into the through-hole so as to be biased toward the upper surface side of the plug main body. When pressurized into the injection port for chemicals, etc., the periphery of the through hole below the lower end of the air replacement pipe is tightened in a lip shape by the tightening pressure of the elastic body, the repulsive force of this tightening pressure and the stress relaxation action, etc. 18. The sealing device for an injection port for a liquid medicine or the like according to any one of claims 15 to 17, wherein the check valve is configured to be a check valve against the outflow of water. 19. A bottomed hole having a bottom at the bottom instead of the through hole for inserting the air displacement pipe according to any one of claims 15 to 18, wherein the air displacement pipe is inserted and installed in this hole,
A cut portion or small hole penetrating in the vertical direction is provided at the bottom of the hole, and when the stopper body is pressed into the injection port of the chemical solution or the like, the elastic member is tightened by the pressure and the stress relaxing action. A sealing device for an injection port for a drug solution or the like, characterized in that a tightening pressure is generated. 20. An annular concave groove is provided around an upper surface of a plug body made of an elastic body formed by vertically penetrating a linear cut portion or slit portion in the center portion, and the plug body is injected and extracted with a chemical solution or the like. An annular projection having a larger volume than the annular groove fitted to the annular groove is formed on the inner surface of the cap for fixing to the mouth, and the annular projection is press-fitted into the annular groove to perform the cutting. A sealing device for injecting / extracting an inlet for a drug solution or the like, wherein a sealing pressure is generated by generating a tightening pressure in a portion or a slit portion. 21. The syringe or connector according to claim 1, further comprising an annular retaining projection provided at a tip of the tip of the syringe or the connector.
0, when inserted into a cut portion, a slit portion, or a conical hole of the stopper body according to any one of the above items, the tip portion of the syringe or the connector is configured to be locked by the retaining protrusion to prevent the stopper from coming off. A sealing device for an injection / extraction port for a drug solution or the like, characterized in that: 22. A plug body which is press-fitted into said liquid injection opening with a predetermined interference, and is fixedly secured to said liquid injection opening by a cap, wherein the upper surface of said plug main body is a flat surface. A concave portion is formed on the lower surface side, and a cut portion, a slit portion, or a conical hole is formed at the center portion, and a cut portion at the center portion is formed on the flat surface of the upper surface of the plug body. An annular convex portion that fits into the center hole of the cap is formed around the portion or the slit portion or the conical hole, and the inside of the annular convex portion has a flat surface so as to be flush with the outside. Characterized in that the inner peripheral surface is formed as an inverted conical hole-shaped tapered surface, and the tapered surface and the flat surface inside the annular convex portion on the upper surface of the plug body are formed so as to be smoothly continuous with each other. Mouth sealing device. 23. A seal for an injection port for injecting and extracting a chemical solution, wherein the inside of the annular convex portion on the upper surface of the stopper body according to claim 22 is a flat surface higher than the outside or a convex arcuate surface. apparatus. 24. The chemical liquid according to claim 22, wherein the concave portion on the lower surface side of the plug body according to claim 22 or 23 has a substantially arc-shaped or tapered inclined surface at a corner between the inner peripheral surface and the ceiling surface. Sealing device for equal injection port. 25. An insertion hole formed at the center of the upper surface of a stopper body made of an elastic body, which penetrates in the vertical direction, at the tip of a syringe or a connector, and an annular groove is formed in the middle of the insertion hole. 3. The chemical liquid or the like according to claim 1, wherein the two semi-disks are combined into a single disk shape, and a valve membrane member having a cut portion or a slit portion at the joint is hermetically fitted and held. Sealing device for injection port. 26. An insertion hole formed at the center of the upper surface of a stopper body made of an elastic body to which a predetermined interference has been given, and an insertion hole at the tip of a syringe or connector, and a root at one lower end of the insertion hole. A flap valve for opening and closing the lower end opening of the insertion hole with the base portion as a fulcrum, and always closing the lower end opening by elasticity and / or internal pressure of the base portion, is connected to the insertion hole. A sealing device for an injection port for a drug solution or the like, characterized in that it is mounted through a plastic inner cylinder and a lower end of the inner cylinder projects from a lower end of the insertion hole to form a valve seat. 27. An insertion hole at the center of the upper surface of the stopper body according to any one of claims 1 to 20, 25, and 26, wherein the insertion hole is at the tip of a syringe or a connector, and fitted into the insertion hole or the insertion hole. A female screw groove is formed on the inner surface of the attached plastic inner cylinder, and the female screw groove and a male screw ridge formed at the distal end of the syringe or the connector are screwed together so that they can be retained and locked. Sealing device for injection port for chemicals etc. 28. An insertion hole for a tip of a syringe or a connector is formed in the center of the upper surface of the stopper body according to any one of claims 1 to 20, 25, and 26, and is fitted in the insertion hole or the insertion hole. One or more annular locking portions are formed on the inner surface of the plastic inner cylinder fitted together, and the annular locking portion and the annular locking portion formed at the distal end of the syringe or the connector are prevented from coming off and locked. A sealing device for an injection port for a drug solution or the like, which is detachable.