JP2001224675A - Pad and device for vaporizing liquid medicine - Google Patents

Abstract

PROBLEM TO BE SOLVED: To keep the well-balanced vaporization of an aromatic component and a medicine stable with the elapse of time over a long period of time by suppressing initial excessive vaporization wherein a part of the medicine or solvent easy to vaporize is largely vaporized in an initial stage. SOLUTION: A liquid medicine vaporization pad is constituted by coating or impregnating the vaporization surface of a vaporization member with a vaporization adjusting substance. A liquid medicine vaporization device is equipped with liquid medicine vaporization pad.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a liquid drug vaporizing pad and a liquid drug vaporizing device provided with the pad.
More specifically, a liquid medicine characterized by applying or impregnating a volatilization adjusting substance to a volatilization surface of a volatilization member in order to suppress excessive volatilization of an initial liquid medicine and to balance the amount of volatilization over time. The present invention relates to a liquid drug volatilization device comprising a volatilization pad and the liquid drug volatilization pad.

[0002]

2. Description of the Related Art Conventionally, there are various types of liquid medicine volatilizing devices. A container for storing a liquid medicine, a suction member inserted into the container and sucking the liquid medicine in the container, and a sucked liquid medicine A volatilization device including a volatilization member for volatilizing the gas is known. Further, among household fragrances, a water-based liquid volatilizer using water as a volatilizing medium is marketed from the viewpoint of safety and economy. In the aqueous base liquid volatilization apparatus, it was difficult to volatilize or diffuse the fragrance component continuously and satisfactorily due to the system in which the water content of the base is low and the fragrance rate is low. In order to solve such difficulties, a method of increasing the volatilization by increasing the volatilization area by using a volatilization pad formed of a capillary body as a volatilization member on the volatilization surface of the aqueous base liquid volatilization device has been taken. .

[0003] When a liquid drug volatilizes volatile components by the volatilizer, the liquid drug contains non-volatile components such as surfactants and dyes in addition to volatile components such as fragrances, deodorants, and insecticides. These are also sucked up by the sucking member together with the volatile components and sent to the volatile member. For this reason, the non-volatile component remains on the volatilization surface of the volatilization member without volatilizing with the passage of time, causing clogging, reducing the volatilization area of the volatilization member, and reducing the volatilization amount of the volatilization component.

For example, the fragrance component used in the fragrance or the like is composed of a combination of a plurality of components such as a component which is easy to volatilize due to a difference in boiling point, a component which is difficult to volatilize, and a component located in between. A moderate incense tone is obtained by the volatilization balance of the components, but the volatilization area is reduced by the non-volatile components remaining on the volatilization surface of the volatilization member, the volatilization balance of the aroma component is disrupted, and the change in the incense tone is remarkable. The merchandise value had decreased.

Further, in a conventional volatilization apparatus provided with a volatilization pad, it is said that a stable volatilization of a drug over time cannot be obtained due to excessive volatilization in which a portion of easily volatilizable drug components and solvents are volatilized at an initial stage. There are fatal flaws.

Therefore, in order to solve such a problem, a volatilization device including a container for accommodating a liquid medicine, a suction member for sucking up the liquid medicine, and a volatilization member for volatilizing the liquid medicine sucked by the suction member is provided. A volatilization device in which a part of a volatilizing member is covered with an impermeable member that does not allow a volatilized component of a liquid drug to pass therethrough, and a volatilization part is formed in the portion to store the non-volatilized component of the liquid drug (JP-A-11-1232).
No. 33), a container for accommodating a liquid medicine, a suction member for sucking the liquid fragrance in the container, and a transpiration unit for transpirating the sucked liquid fragrance, and at least the transpiration unit has a hygroscopic property. A fragrance (see Japanese Patent Application Laid-Open No. H11-155942), a liquid fragrance, or a deodorant, which is constituted by a superposed body of paper, and the superposed body has a honeycomb structure when opened. Using a core or a base material for volatilizing through a core and a pad as a volatilizing surface, and an outer wall or a lid is automatically opened and closed to achieve an aromatic deodorizing effect (Japanese Patent Application Laid-Open No. 07-031670). Publications have been made.

[0007]

However, it is effective to volatilize components which are difficult to volatilize by expanding the volatilization area and volatilize a liquid of a certain concentration for a long period of time. Has not been resolved at all in the early excess volatilization, which is more volatile at the beginning,
There has been a problem that the volatilization of the fragrance component and the drug, which are stable over time, cannot be maintained for a long time.

[0008]

The inventors of the present invention have conducted intensive studies to solve the above-mentioned problems. As a result, the present inventors have developed a liquid medicine volatilization pad in which a volatilization adjusting substance is applied or impregnated on a volatilization surface of a volatilization member. By equipping a conventional liquid drug volatilization device, it is possible to obtain a liquid drug volatilization device capable of suppressing excessive volatilization in the initial stage, homogenizing the amount of volatilization over time, and volatilizing a constant concentration of the liquid drug over a long period of time. The present invention has been completed. Therefore, an object of the present invention is to suppress the initial excess volatilization of an aqueous-based liquid drug that has solved the conventional problems, mitigate the decrease in the amount of drug volatilization over time, and reduce the amount of volatilization over time during use. It is an object of the present invention to provide a liquid medicine volatilization pad capable of balancing and continuously evaporating a liquid medicine, and a liquid medicine volatilization device provided with the pad. Hereinafter, specific embodiments of the present invention will be described in more detail.

[0009]

BEST MODE FOR CARRYING OUT THE INVENTION A liquid chemical vaporizing device according to the present invention comprises a liquid chemical vaporizing pad characterized by applying or impregnating a volatilization adjusting substance to a volatilizing surface of a volatilizing member, and a pad provided with the pad. , A container for storing a medicine, a suction member for sucking up the medicine, and a volatilization member for volatilizing the sucked medicine.

The liquid medicine is not particularly limited, but examples thereof include fragrance, deodorant, bactericide, insect repellent, repellent, attractant, insecticide and the like.

Examples of the vaporizing member of the liquid chemical vaporizing pad of the present invention include natural fibers such as pulp, cellulose, cotton and hemp, and fibrous materials such as synthetic fibers such as polyethylene, polypropylene, rayon, acetate, nylon and tetron. Or, a porous material such as unglazed or ceramics may be used.

The volatilization regulating substance is not particularly limited as long as it can control the volatilization of the drug. For example, isobutylene / maleic anhydride copolymer, starch / acrylonitrile graft copolymer, polyacrylate , Vinyl acetate-acrylate copolymers and other superabsorbent resins and methylcellulose, CMC, polyvinyl alcohol, carboxyvinyl polymer, carrageenan,
Examples thereof include a water-soluble polymer such as agar and gellan gum, and preferably a water-absorbent resin.
The application amount of the volatilization adjusting substance is 5 to 200 g / m ² ,
Preferably, 10 to 100 g / m ² can be exemplified.

As a method of applying or impregnating the volatilization adjusting substance to the volatilization surface of the volatilization member, for example, a method of applying a volatilization adjusting substance solution to a surface layer of a volatilization pad and impregnating the pad surface with a volatilization adjusting substance (FIG. 1) ), When a fibrous non-woven body is used as a volatile pad, a volatilization adjusting substance is incorporated between the fibrous materials during the production of the non-woven body, and the fibrous material is subjected to heat and pressure fusion, etc., and is embedded in the surface and inside of the molded body. (Fig. 2), and a sizing method (Fig. 3) in which a volatilization control substance is sandwiched between several volatilization pads, laminated and formed, and a treatment for changing the fibrous capillary property is performed. it can.

The volatilization surface of the liquid medicine volatilization pad obtained by processing the volatilization member with the volatilization control substance in this manner is subjected to a process of applying or impregnating the volatilization control substance, thereby obtaining a base surface and a surface layer. Different capillary properties are imparted to the layer or the base layer and the three layers of the middle layer and the surface layer. In other words, by adding the properties of the volatilization regulating substance to the capillary properties of the volatilization pad itself, a plurality of capillary property heterogeneous phases will be formed,
The volatility of the liquid drug is improved. In other words, provisional filling is performed by applying or impregnating the volatilization adjusting substance to the volatilization member, suppressing excessive volatilization at the initial stage, which was a fatal defect of the conventional technology, and homogenizing volatilization until the second half of liquid volatilization. Is achieved.

Further, in the conventional volatilization apparatus, the residue of the solubilizer generated by the volatilization of the volatilization pad residue was extremely clogged on the pad surface due to concentration, thickening, and retention.
In the present invention, clogging can be improved by processing the surface of the volatilization pad with a volatilization adjusting substance. In other words, by applying or impregnating the volatilization adjusting substance to the surface layer of the volatilization pad by a processing method such as a coating method, a partial impregnation method or a sizing method (bleeding prevention treatment), the movement of the solubilizer to the volatilization pad surface is reduced. In addition, the volatility of the volatilization adjusting substance acts to maintain the chemical volatility by absorbing moisture, thereby mitigating the decrease in the amount of chemical volatilization over time, balance the amount of volatilization over time during use, and maintain A liquid drug volatilization device with excellent properties can be obtained.

Hereinafter, the present invention will be described in more detail with reference to examples.

[0017]

EXAMPLE 1 Pigment sheet (Honshu Paper: dry pulp nonwoven fabric, diameter 50 mm, thickness 2.1 mm) as a volatile pad was coated on a surface with an isobutylene / maleic anhydride copolymer (Kuraray KI gel A solution (25% aqueous solution): KI). Gel B liquid (crosslinking agent) = 100:
1.25) Volatile pad A (the present invention), which was coated with 0.2 g of the mixed solution uniformly, further dried and coated and impregnated with 0.05 g of superabsorbent resin on the pad surface, and isobutylene / maleic anhydride Volatilization pad B (comparative product 1) in which 0.05 g of the copolymer powder (Kuraray KI gel 201K, particle size: 20 mesh) is evenly spread on the surface of a pigeon sheet;
(Comparative product 2) was prepared.

These volatile pads were placed in one of the fragrance containers shown in FIG.
20 g was filled in a container, and a volatilization test was performed at room temperature.

Formulation of fragrance liquid 95% ethanol 5 POE nonyl phenyl ether 2.8 Dioctyl sodium sulfosuccinate solution 1.2 Perfume (lavender # 1450) 2 Water 89 100 (% by weight) From the results of changes in the volatilization weight in the volatilization test The amount of volatilization per day for each volatilization pad is shown in Table 1 and FIG.

[0020]

[Table 1]

From Table 1 and FIG. 3, the volatilization amount per day tended to decrease from the initial volatilization amount for all of the three types of volatilization pads.

However, when the volatilization pad A of the present invention is compared with the conventional volatilization pad C (comparison product 2), the amount of volatilization per day is only at the volatilization pad C in the early stage of volatilization (15 days). From the middle period (41st), and conversely, it works to promote the amount of volatilization per day more than conventional volatilization pads, and balances the amount of volatilization over time. Was done.

In addition, the volatilization pad A of the product of the present invention was also found to have excellent fragrance persistence after the middle stage in the evaluation of the sensory test, and the amount of volatilization over time during the test period was balanced. It has been found that it clearly has excellent durability.

As for the volatile pad B (Comparative product 1), the KI gel 201K powder on the volatile surface swelled and the apparent volatile surface was enlarged. The same volatilization amount as that of the volatilization pad C (Comparative product 2) was obtained, and the effect of improving the conventional volatilization pad was not recognized.

In the sensory test evaluation of the volatile pad B (Comparative product 1), the persistence of the fragrance after the middle stage was not as long as the volatile pad A of the product of the present invention.

[0026]

EFFECTS OF THE INVENTION The liquid drug volatilization pad and the liquid drug volatilization apparatus provided with the pad of the present invention suppress the initial excessive volatilization of the aqueous base liquid drug, reduce the decrease in the amount of drug volatilization over time, During the period of use, the amount of volatilization over time can be balanced and the liquid drug can be volatilized continuously.

[0027]

[Brief description of the drawings]

FIG. 1 is a cross-sectional view of a volatilization pad of the present invention in which a pad surface is impregnated with a volatilization preparation substance, and hatched portions are explanatory diagrams showing a volatilization adjustment substance.

FIG. 2 is a cross-sectional view of a volatilization pad of the present invention in which a volatilization preparation substance is embedded on the surface and inside of the pad;

FIG. 3 is a cross-sectional view of a volatilization pad of the present invention in which a volatilization control substance is sandwiched between pads and laminated, and hatched portions are explanatory views showing the volatilization control substance.

FIG. 4 is an explanatory view showing a sectional view of a container for filling a liquid medicine.

FIG. 5 is an explanatory diagram showing a diagram representing a change in volatilization weight in Example 1.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Volatilization pad 2 Volatilization pad support 3 Suction core 4 Container body

 ──────────────────────────────────────────────────続 き Continued on the front page F term (reference) 3E068 AA35 AB10 AC09 CC01 DD34 DD40 4C002 AA01 AA03 DD03 DD12 DD13 EE05 EE07 FF10

Claims (3)

[Claims] 1. A pad for volatilizing a liquid drug, wherein a volatilization adjusting substance is applied or impregnated on a volatilization surface of a volatilization member. 2. A liquid medicine volatilization apparatus comprising the liquid medicine volatilization pad according to claim 1. 3. The liquid drug volatilization pad according to claim 1, wherein the volatilization adjusting substance is a superabsorbent resin.