JP2001206832A - Cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a cosmetic capable of providing the skin with not only whiteness but also lightness/transparent feeling of the essential skin and an excellent skin care effect when the cosmetic is used. SOLUTION: This cosmetic comprises (A) a water-soluble moisturizing component selected from an amino acid, an organic acid or its salt, a saccharide, urea, glycinebetaine and a guanidine derivative, (B) a blood circulation promotion component and (C) a bleaching component.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic having an excellent skin care effect and an effect of restoring the original brightness and transparency of the skin.

[0002]

2. Description of the Related Art Hitherto, blackening of skin due to sunburn has been attributed to the fact that tyrosine present in skin becomes melanin pigment by the action of tyrosinase, and this melanin is excessively produced. In order to prevent or treat this pigmentation, cosmetics comprising a whitening component such as L-ascorbic acid and derivatives thereof, colloidal sulfur, hydrogen peroxide and hydroquinone have been proposed.

[0003]

However, these whitening cosmetics have insufficient storage stability, or do not have a sufficient whitening effect, or lighten dark skin. Although the effect is recognized, the skin care effect is problematic, and it has been difficult to expect the original brightness and transparency of the skin by improving the original function of the skin. Therefore, there is a demand for the development of a cosmetic that is not only effective in preventing or treating pigmentation, but also has an excellent effect of restoring the original brightness and transparency of the skin and has a high skin care effect.

[0004]

Means for Solving the Problems The present inventor has proposed a whitening ingredient,
It has been found that if a specific water-soluble moisturizing component and a blood circulation promoting component are combined and compounded, not only a whitening effect but also an effect of improving the original brightness and transparency of the skin and a cosmetic having a high skin care effect can be obtained. .

That is, the present invention provides the following component (A):
(B) and (C): (A) Contains a water-soluble moisturizing component selected from amino acids, organic acids or salts thereof, saccharides, urea, glycine betaine and guanidine derivatives, (B) a blood circulation promoting component, and (C) a whitening component. To provide cosmetics.

[0006]

BEST MODE FOR CARRYING OUT THE INVENTION Component (A) used in the present invention
Is a water-soluble moisturizing component, and examples of amino acids include glycine, alanine, valine, leucine, arginine, lysine, glutamic acid and the like. Examples of the organic acid or a salt thereof include sodium pyrrolidonecarboxylate, lactic acid, succinic acid, sodium lactate, citric acid, sodium citrate and the like. Examples of the saccharide include hyaluronic acid, chondroitin, dermatan sulfate, glucose, mannose, galactose, and maltose. Glycine betaine includes glycine betaine having a C ₄ -C ₂₄ alkyl group. As the guanidine derivative, the following general formula (1) or (2) described in JP-A-10-287541.

[0007]

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[In the formula (1), X is a linear or branched hydrocarbon group, or an aromatic ring group which may have a substituent,
It represents an aralkyl group, a cycloalkyl group or an oxacycloalkyl group, and Y represents a hydrogen atom or a linear or branched hydrocarbon group. In the formula (2), A and B represent an alkylene group having 2 to 8 carbon atoms which may be the same or different, and D represents a bond, -CO- or 1 to 1 carbon atoms which may have a substituent. 6 represents an alkylene group, E is a hydrogen atom,
A lower alkyl group, an aralkyl group or an aryl group which may have a substituent, m represents a number of 1 to 6, n represents a number of 0 to 6, R ¹ represents a hydrogen atom, a lower alkyl group; Or-(AO) _m- (BO) _n -DE. However, when R ¹ is a methyl group,-(AO) _m- (BO) _n -DE is not a hydroxyethyl group.
Or an acid addition salt thereof.

Among the guanidine derivatives of the above formula (1),
In particular, methylguanidine, ethylguanidine, n-propylguanidine, isopropylguanidine, n-butylguanidine, 2-methylpropylguanidine, t-butylguanidine, n-pentylguanidine, n-hexylguanidine, phenylguanidine, N-methyl-N -Phenylguanidine, 4-hydroxyphenylguanidine, 4-methoxyphenylguanidine, 4-ethoxyphenylguanidine, 3- (4-guanidinophenyl) propanoic acid, 4- (4-guanidinophenyl) butanoic acid,
2-methoxy-5-methylphenylguanidine, cyclohexylguanidine, benzylguanidine, glucopyranosylguanidine, 4-guanidinophenyl acetate are preferred.

Also, among the guanidine derivatives of the formula (2),
Particularly, 2- (2-hydroxyethoxy) ethylguanidine and 5-hydroxypentylguanidine are preferable.

Furthermore, as the guanidine derivative, 2- (2-hydroxyethoxy) ethyl guanidine succinate is particularly preferred.

These components (A) can be used singly or in combination of two or more.
It is preferable to mix it in an amount of from 20 to 20% by weight (hereinafter simply referred to as%) from the viewpoint of skin care effect and effect of improving skin's original brightness and transparency, particularly from 0.01 to 10%, more preferably from 0.01 to 10%.
The addition of 5% is more preferable in terms of stability.

The component (B) used in the present invention is not particularly limited as long as it is a blood circulation-promoting component usually used in cosmetics, and examples thereof include tocopherol nicotinate, tocopherol acetate, nicotinamide, rice germ oil, bodaiju Extracts, maroni extract, yuzu extract and the like are mentioned, and yuzu extract, bodaiju extract and nicotinamide are particularly preferable.

The component (B) can be used alone or in combination of two or more. In the case of tocopherol nicotinate, tocopherol acetate, nicotinamide, and rice germ oil, 0.01 to 5 parts % Is preferable from the viewpoint of the effect of improving the original brightness and transparency of the skin, and particularly 0.01 to 2%, more preferably 0.01 to 2%, from the viewpoint of stability. In the case of a plant extract, 0.00001 to 5%, especially 0.0001 to 3%, and more preferably 0.0001 to 2% of dry solid content in the total composition is blended for the original brightness and transparency of the skin. It is preferable in terms of the effect of improving the feeling. As the plant extract, those commercially available as an extract or the like can be used as they are.

The whitening component of the component (C) used in the present invention is not particularly limited as long as it is a whitening component usually used in cosmetics. For example, L-ascorbic acid and its derivatives,
Hydroquinone derivatives such as arbutin, kojic acid and its derivatives, ellagic acid and its derivatives, placental extracts; chamomile, tea, clove, fruit, groundnut, licorice, loquat, orange peel, ginseng, peony, mountain herb, germ winter And plant extracts such as ginger, matsukasa, mulberry bark, magnolia, chinko, asenyaku, yellow gon, aloe, altea, spirea, dutch mustard, kina, comfrey, rosemary, and funnel.
Of these, chamomile, Altea and tea are particularly preferred.

Component (C) can be used alone or in combination of two or more. L-ascorbic acid and its derivatives, hydroquinone derivatives such as arbutin, kojic acid and its derivatives, ellagic acid and its derivatives, placenta extraction When a substance is used, 0.01 to 50%, especially 0.1%, of the total composition.
It is preferable to add 0.5 to 30%, more preferably 0.1 to 20%, from the viewpoint of a sufficient whitening effect and an effect of improving skin original brightness and transparency. In the case of a plant extract, 0.00001 to 5%, particularly 0.0001 to 3%, as a dry solid content in the whole composition.
%, More preferably 0.0001 to 2%, from the viewpoint of a sufficient whitening effect and an effect of improving the skin's original brightness and transparency. As the plant extract, a commercially available extract or the like can be used as it is.

The cosmetic of the present invention comprises the above component (A),
By containing (B) and (C), the original brightness and transparency of the skin are improved and a skin care effect (skin roughness improving effect) is obtained.
When it is set, it is more remarkably exhibited. That is, when the pH is adjusted to 3 to 6 by adding a pH adjuster, the above effects, particularly the skin care effect, are improved, and it is also preferable from the viewpoint of safety. A more preferred pH is between 3.5 and 5.5.

Further, the cosmetic of the present invention, when its appearance is made transparent or translucent, has not only an advantage in appearance, but also the above-mentioned effect is further improved based on the fact that the active ingredient is solubilized. Here, the term “transparent or translucent” refers to a range of 20 to 100 when the transmittance of 550 nm is measured using a spectrophotometer (UV-160) manufactured by Shimadzu Corporation and the transparency of distilled water is set to 100 as a control. Means In order to make the cosmetic of the present invention transparent or translucent, it is preferable to mix water and a solubilizer with the above components. Here, the solubilizing agent includes a hydrophilic surfactant, for example, a nonionic surfactant.

Examples of the nonionic surfactant include polyoxyethylene castor oil and hydrogenated castor oil derivatives such as polyoxyethylene castor oil and polyoxyethylene castor oil; polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan tetra Polyoxyethylene sorbitan fatty acid esters such as oleate; fatty acid esters of polyoxyethylene glycol such as polyoxyethylene glyceryl monoisostearate and polyoxyethylene glyceryl triisostearate; polyoxyethylene octyl dodecyl ether, polyoxyethylene lauryl ether Polyoxyethylene alkyl ethers such as polyoxyethylene cetyl ether, polyoxyethylene stearyl ether, and polyoxyethylene nonylphenyl ether; Other polyoxyethylene-added surfactants such as Le, polyglycerol alkyl ethers,
Polyglycerin fatty acid esters, sucrose fatty acid esters and the like can be mentioned.

From the viewpoint of safety, the content of the hydrophilic surfactant is 0.05 to 30%, preferably 0.05 to 1% in the total composition.
0% is preferred. Water is 40 to 99.9 in the cosmetic of the present invention.
7%, particularly preferably 70 to 99.97%,
The solubilizing agent is used in a weight ratio of 0.01: 1 to component (A).
10: 1, particularly preferably 0.01: 1 to 5: 1.

The cosmetic of the present invention may further contain other components which are usually added to cosmetics. For example, non-volatile silicone can be blended with liquid oil such as squalane and fatty acid ester for the purpose of imparting a refreshing feeling, and squalane and fatty acid ester can be blended with the purpose of improving spreadability and familiarity with the skin, as well as ultraviolet absorbers, chelating agents, and preservatives. And a medicinal agent such as a pigment, a fragrance, a viscosity modifier, and an anti-inflammatory agent.

The cosmetic of the present invention is produced by a conventional method by blending the above-mentioned components. Examples of the form include lotion, lotion, serum, milky lotion, cream and the like. Among them, lotion, lotion and beauty Liquids are preferred.

The cosmetic of the present invention is preferably used by applying it to the skin with hands or cotton or the like in the same manner as ordinary basic cosmetics.

[0024]

Examples 1 to 17 and Comparative Examples 1 to 3 Transparent or translucent lotions having the formulations shown in Tables 1 to 10 were prepared, and the effect of improving rough skin (skin care effect); and the effect of imparting skin brightness and transparency. Was evaluated. The results are shown in Tables 1 to 10.

[0025]

[Table 1]

[0026]

[Table 2]

[0027]

[Table 3]

[0028]

[Table 4]

[0029]

[Table 5]

[0030]

[Table 6]

[0031]

[Table 7]

[0032]

[Table 8]

[0033]

[Table 9]

[0034]

[Table 10]

[Evaluation Method] 1) Evaluation of the Effect of Improving Rough Skin A glass cup (inner diameter: 2 cm) containing acetone / ether (volume ratio: 1: 1) was attached to the inner side of a human forearm, and degreased for 15 minutes. Induced rough skin. After applying a fixed amount of each sample to half the area of the rough skin every morning and evening for 5 days, the effect of improving the rough skin was observed by visual judgment by five specialized panelists. Evaluation criterion 5: Extreme recovery: All five panelists judged that the recovery was remarkable. 4: Recovery: Three or more panelists judged that the recovery was almost complete. 3: Slight recovery: One or two of the panelists were judged to have largely recovered. 2: No recovery: All panelists did not judge that recovery was successful. 1: Deteriorated: One or more of the panelists judged that it was deteriorating.

2) Evaluation of Skin Brightness and Transparency After applying a fixed amount of each sample to the human face for 30 days every morning and evening, the brightness and transparency were evaluated by visual evaluation by five expert panelists.
The effect of improving the transparency was observed. 5: Extreme recovery: All five panelists judged that the recovery was remarkable. 4: Recovery: Three or more panelists judged that the recovery was almost complete. 3: Slight recovery: One or two of the panelists were judged to have largely recovered. 2: No recovery: All panelists did not judge that recovery was successful. 1: Deteriorated: One or more of the panelists judged that it was deteriorating.

From Tables 1 to 10, it can be seen that the cosmetics containing the components (A), (B) and (C) are excellent in the effect of improving skin brightness and transparency and also in the effect of improving rough skin. Understand. In addition, the difference between 5 and 4, which are the evaluation criteria of the skin brightness / transparency improvement effect in Tables 1 to 10, was clearly different visually.

[0038]

By using the cosmetic of the present invention, not only whiteness but also the original brightness and transparency of the skin can be imparted to the skin, and an excellent skin care effect can be obtained.

 ────────────────────────────────────────────────── ─── Continuing on the front page (72) Inventor Junsuke Kiba 2-1-3 Bunka, Sumida-ku, Tokyo F-term in Kao Corporation Research Laboratories 4C083 AA072 AA112 AA122 AB282 AC102 AC122 AC182 AC231 AC292 AC302 AC482 AC581 AC582 AC612 AC642 AC681 AC711 AC741 AC742 AC842 AD191 AD352 AD662 BB51 CC01 CC04 DD01 DD23 EE12 EE16

Claims (2)

[Claims] 1. The following components (A), (B) and (C): (A) a water-soluble humectant selected from amino acids, organic acids or salts thereof, saccharides, urea, glycine betaine and guanidine derivatives, (B) Cosmetics containing a blood circulation promoting component and (C) a whitening component. 2. The cosmetic according to claim 1, which has a pH of 3 to 6.