JP2001072963A - Water-in-oil type bubblelike aerosol composition and preparation thereof - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a water-in-oil type bubblelike aerosol composition forming a stable emulsion and imparting a creamlike foam having a cool feeling by comprising a stock solution and a propellant, the stock solution consisting of an oil component, water and a lipophilic surfacant, and the propellant consisting of dimethyl ether and a carbon dioxide gas. SOLUTION: In a water-in-oil type bubblelike aerosol composition comprising a stock solution and a propellant, the composition comprises 60-98 wt.% of the stock solution consisting of 0.1-50 wt.% of an oil component, 50-95 wt.% of water and 0.1-10 wt.% of a lipophilic surfactant having not more than 9 of HLB, and 1-30 wt.% of dimethyl ether and 0.01-10 wt.% of a carbon dioxide gas as the propellant. A content of the dimethyl ether in the propellant is preferably 10-99.7 wt.%. As the oil component to be used in the stock solution is desirable a hydrocarbon, ester oil, a higher fatty acid, a silicone, fats and oils, wax, or the like, the oil component imparting permeability and gloss to a skin and hair, protecting them to retain a health state and bringing good extensibility.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a water-in-oil type foam aerosol composition and a method for producing the same. More specifically, the present invention relates to a water-in-oil type foam aerosol composition which gives a creamy foam having a cooling sensation containing dimethyl ether and a method for producing the same.

[0002]

2. Description of the Related Art Conventionally, in order to prepare a water-in-oil aerosol composition, it is necessary to heat each component and to stir it with, for example, a homomixer, and the operation is very complicated. Was. In addition, even when the formulation and manufacturing conditions are sufficiently designed, during mass production, the resulting water-in-oil aerosol composition varies, making management difficult and reducing stickiness during use. When the water content is increased for this purpose, the viscosity of the stock solution increases, the emulsifying property deteriorates, and there is a problem that layer separation easily occurs.

[0003] JP-A-6-329532 discloses that an oil component is 3 to 50% by weight, a nonionic surfactant is 0.1 to 10% by weight.
A water-in-oil aerosol composition comprising 50-97% by weight of a stock solution containing 50% -95% by weight and a water component and 3-50% by weight of a liquefied gas and a method for producing the same are described. This composition uses a stock solution in which a specific surfactant is mixed in at least one of an oil component and a water component in a specific mixing ratio, and has excellent storage stability and affinity for skin, hair, and the like. It gives a refreshing feeling. In this composition, liquefied petroleum gas (LPG) is mainly used as a liquefied gas, but the emulsion is stable because LPG is not dissolved in water and has a small polarity.

Another liquefied gas used in aerosol products is dimethyl ether. This is an amphiphilic substance, which has polarity and therefore has different injection characteristics from liquefied petroleum gas. However, when dimethyl ether is blended with the water-in-oil aerosol composition, there is a problem that the emulsification of the composition is destroyed, and dimethyl ether cannot be blended.

[0005]

SUMMARY OF THE INVENTION An object of the present invention is to provide a water-in-oil foam aerosol composition which forms a stable emulsion and gives a creamy foam having a cooling sensation.

[0006]

As a result of study to solve the above problems, it has been found that, generally, when dimethyl ether is blended, it is difficult to form an emulsion or the stability of the emulsion deteriorates. As a result, it has been found that the stability of the emulsion is improved despite containing dimethyl ether, and the present invention has been completed.

That is, the present invention relates to an aerosol composition comprising a stock solution and a propellant, wherein the stock solution comprises an oil component, water and a lipophilic surfactant, and the propellant comprises dimethyl ether and carbon dioxide gas. An aerosol composition (Claim 1), wherein the stock solution is 0.1 to 50% by weight of an oil component;
0.1 to 10% by weight of lipophilic surfactant and 50 to 9 of water
2. A water-in-oil foam aerosol composition according to claim 1, comprising 5% by weight (claim 2), 60 to 98% by weight of a stock solution, 1 to 30% by weight of dimethyl ether and 0.02% of carbon dioxide gas.
The water-in-oil foam aerosol composition according to claim 1 or 2 containing 1 to 10% by weight (Claim 3), wherein the lipophilic surfactant has an HLB of 9 or less. 4. The water-in-oil foam aerosol composition according to claim 1, 2 or 3, wherein the content of dimethyl ether in the propellant is 10 to 99.7% by weight. Claim 5), and dispensing an oil phase containing a surfactant and an oil component, and an aqueous phase containing a water-soluble component into a container, and then filling and shaking with dimethyl ether and carbon dioxide gas to form a water-in-oil type. The present invention relates to a method for producing a water-in-oil type foam aerosol composition according to claim 1, wherein an emulsion is formed (claim 6).

[0008]

DETAILED DESCRIPTION OF THE INVENTION The aerosol composition of the present invention is characterized in that the stock solution comprises an oil component, water and a lipophilic surfactant, and the propellant comprises dimethyl ether and carbon dioxide. / O-type) foam aerosol composition.

The lipophilic surfactant is a component that acts as an emulsifier to obtain a water-in-oil aerosol composition. Such lipophilic surfactants include nonionic surfactants, anionic surfactants, cationic surfactants, amphoteric surfactants, polymer surfactants, natural surfactants and the like. Among them, lipophilic ones can be used alone or in appropriate combination of two or more kinds.

Examples of the nonionic surfactant include sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquistearate, sorbitan monooleate, sorbitan sesquioleate, sorbitan sesquioleate, sorbitan trioleate and the like. Fatty acid esters; glycerin fatty acid esters such as glyceryl monostearate and glyceryl monooleate; decaglycerin fatty acid esters such as decaglyceryl tristearate and decaglyceryl trioleate; diglyceryl monooleate and tetraglyceryl monooleate Polyglycerin fatty acid esters; polyoxyethylene sorbite fatty acid esters such as POE (n) -sorbitol tetraoleate;
Polyethylene glycol fatty acid esters such as POE (n) -monostearate and POE (n) -monooleate; POE (n) -cetyl ether, POE (n)-
Polyoxyethylene alkyl ethers such as stearyl ether and POE (n) -oleyl ether; POE
(N) POP (m) -cetyl ether, POE (n) P
Polyoxyethylene polyoxypropylene alkyl ethers such as OP (m) -decyltetradecyl ether; POE (n) -nonylphenyl ether, POE
(N) -Polyoxyethylene alkylphenyl ethers such as octylphenyl ether; POE (n) -castor oil, POE (n) -polyoxyethylene castor oil such as hydrogenated castor oil, hydrogenated castor oils, and polyoxyethylene castor Oil derivatives; POE (n) -stearylamine,
Examples include polyoxyethylene alkylamines / fatty acid amides such as POE (n) -oleylamine, POE (n) -stearic acid amide, and POE (n) -oleic acid amide. The above (n) is (CH ₂ CH ₂ O)
(M) is the polymerization number of (CH ₂ CH (CH ₃ ) O), POE is polyoxyethylene, and P is
OP represents polyoxypropylene.

The anionic surfactants include, for example, alkyl sulfates, polyoxyethylene alkyl ether sulfates, N-acyl amino acid salts, N-acylmethyl taurine salts, polyoxyethylene alkyl ether acetates, alkyl phosphates Salt, polyoxyethylene alkyl ether phosphate, soap base, fatty acid soap such as sodium laurate, sodium palmitate, higher alkyl sulfate such as sodium lauryl sulfate, potassium lauryl sulfate, POE lauryl sulfate triethanolamine, POE Alkyl ether sulfates such as sodium lauryl sulfate; N-acyl sarcosine acids such as sodium lauroyl sarcosine; N-myristoyl-N-methyltaurine sodium; Sodium, higher fatty acid amides sulfonates such as lauryl methyl tau lid sodium,
Phosphate salts such as sodium POE oleyl ether phosphate and POE stearyl ether phosphoric acid, di-2
-Sulfosuccinates such as sodium ethylhexylsulfosuccinate, monolauroylmonoethanolamide polyoxyethylene sodium sulfosuccinate, sodium lauryl polypropylene glycol sodium sulfosuccinate,
Alkyl benzene sulfonates such as sodium linear dodecylbenzenesulfonate, triethanolamine linear dodecylbenzenesulfonate, sodium linear dodecylbenzenesulfonate, monosodium N-lauroylglutamate, disodium N-stearoylglutamate, N-myristoyl-L-glutamic acid N-acyl glutamates such as monosodium, higher fatty acid ester sulfates such as hydrogenated coconut oil fatty acid sodium glycerin sulfate, sulfated oils such as funnel oil, POE
Alkyl ether carboxylic acid, POE alkyl allyl ether carboxylate, α-olefin sulfonate, higher fatty acid ester sulfonate, secondary alcohol sulfate, higher fatty acid alkylolamide sulfate, sodium lauroyl monoethanolamidosuccinate , N-palmitoyl aspartate ditriethanolamine, sodium caseinate and the like.

Examples of the cationic surfactant include alkylammonium salts, alkyltrimethylammonium salts such as stearyltrimethylammonium chloride and lauryltrimethylammonium chloride, dialkyldimethylammonium salts such as distearyldimethylammonium chloride, and poly (N , N'-dimethyl-3,
Alkylpyridinium salts such as 5-methylenepiperidinium) and cetylpyridinium chloride; alkylbenzylammonium salts such as alkylquaternary ammonium salts and alkyldimethylbenzylammonium salts; alkylisoquinolinium salts; dialkylmorphonium salts; POE alkyl Examples include amines, alkylamine salts, polyamine fatty acid derivatives, amyl alcohol fatty acid derivatives, benzalkonium chloride, and benzethonium chloride.

Examples of the amphoteric surfactant include betaine acetate, imidazolium betaine, 2-undecyl-N, N, N- (hydroxyethylcarboxymethyl) -2-imidazoline sodium, and 2-cocoyl-2.
Imidazoline amphoteric surfactants such as imidazolinium hydroxide-1-carboxyethyloxy disodium salt, 2-heptadecyl-N-carboxymethyl-
N-hydroxyethyl imidazolinium betaine, lauryl dimethylamino acetate betaine, alkyl betaine,
Examples include betaine-based amphoteric surfactants such as amidobetaine and sulfobetaine.

Examples of the polymeric surfactant include sodium alginate and tragacanth rubber.

Examples of the natural surfactant include lecithin, saponin, soybean phospholipid, and soybean lysophospholipid liquid.

The HLB value of the lipophilic surfactant of the present invention is:
It is preferably 9 or less. If it exceeds 9, O / W
Tend to be type emulsions.

The oil component used in the stock solution is a component for imparting or protecting skin and hair from permeation and gloss, and for protecting and maintaining a healthy state and improving spreadability. Such an oil component is preferably at least one selected from hydrocarbons, ester oils, higher fatty acids, silicones, oils and fats, waxes and the like.

Examples of the hydrocarbon include n-hexane, i-hexane, kerosene, petroleum ether, liquid paraffin, squalene, squalane, petrolatum, paraffin, isoparaffin and the like.

Examples of ester oils include isopropyl myristate, cetyl octoate, octyl dodecyl myristate, isopropyl palmitate, butyl stearate, myristyl myristate, decyl oleate, cetyl lactate, myristyl lactate, isocetyl stearate, and isocetyl isostearate. Lanolin acetate, ethyl acetate, butyl acetate, oleyl oleate, cetostearyl alcohol, diisobutyl adipate, diisopropyl sebacate, dioctyl sebacate, hexyldecyl myristate, isocetyl palmitate, adipate-2
-Hexyldecyl and the like.

The higher fatty acids include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, isostearic acid, linoleic acid, linoleic acid, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and the like. Can be

Examples of the silicone include dimethylpolysiloxane, methylphenylpolysiloxane, methylhydrogenpolysiloxane, decamethylpolysiloxane, tetramethyltetrahydrogenpolysiloxane and the like.

The fats and oils include avocado oil, camellia oil, turtle oil, macadamia nut oil, corn oil, mink oil, olive oil, rapeseed oil, sesame oil, castor oil, linseed oil, safflower oil, jojoba oil, malt oil, coconut oil , Palm oil, hydrogenated castor oil and the like.

As the wax, beeswax, lanolin, lanolin acetate, candelilla wax, carnauba wax, whale wax,
Montan wax and the like.

The water component used in the stock solution is a component for giving the obtained water-in-oil aerosol composition a refreshing feeling of use. There is no particular limitation on the water component, and purified water such as distilled water and ion-exchanged water which are used in ordinary aerosol compositions can be used.

The content of the oil component in the stock solution is 0.1
It is preferably from 50 to 50% by weight, more preferably from 3 to 40% by weight. If it is less than 0.1% by weight, an emulsion cannot be obtained by shaking, and if it exceeds 50% by weight, the stock solution loses viscosity and does not foam.

The content of the lipophilic surfactant in the stock solution is preferably 0.1 to 10% by weight,
More preferably, it is about 7% by weight. When the amount is less than 0.1% by weight, no emulsion is formed. When the amount exceeds 10% by weight, stickiness is felt in use feeling.

The content of water in the stock solution is 50-95.
%, More preferably 60 to 90% by weight. When the amount is less than 50% by weight, the stock solution loses viscosity and does not foam, and when the amount exceeds 95% by weight, an emulsion cannot be formed.

In the aerosol composition of the present invention, dimethyl ether is used as a propellant, and carbon dioxide is further added. Addition of dimethyl ether to the stock solution of the above composition does not emulsify, but emulsifies by adding carbon dioxide gas.

The content of the stock solution in the aerosol composition of the present invention is preferably from 60 to 98% by weight,
More preferably, it is 0 to 95% by weight. 60% by weight
If it is less than 100%, the aerosol composition loses viscosity and does not foam, and if it exceeds 98% by weight, it does not foam and does not have a cool feeling.

The content of dimethyl ether is preferably 1 to 30% by weight in the aerosol composition, and 4 to 2% by weight.
More preferably, it is 5% by weight. If the amount is less than 1% by weight, a cooling sensation cannot be obtained, and if it exceeds 30% by weight, an emulsion cannot be obtained.

The content of carbon dioxide gas is preferably 0.01 to 10% by weight, more preferably 0.05 to 8% by weight. If it is less than 0.01% by weight, it does not foam and no emulsion can be obtained, and if it exceeds 10% by weight,
The pressure inside the aerosol can becomes too high, which causes safety problems.

In the propellant, the content of dimethyl ether is preferably from 10 to 99.7% by weight.
More preferably, it is about 99% by weight. When the amount is less than 10% by weight, the composition can be emulsified, but a cooling sensation cannot be obtained. When the amount exceeds 99.7% by weight, a cooling sensation can be obtained, but the composition cannot be emulsified. There is.

The stock solution of the water-in-oil foam aerosol composition of the present invention may contain, in addition to an oil component, a lipophilic surfactant, and water, alcohols, high molecular compounds, and the like according to the intended use. it can.

Examples of the alcohols include lower alcohols such as ethanol, propanol, isopropanol, isobutyl alcohol and t-butyl alcohol. Ethylene glycol as polyhydric alcohol,
Dihydric alcohols such as propylene glycol and 1,3-butylene glycol, trihydric alcohols such as glycerin and trimethylolpropane, tetrahydric alcohols such as pentaerythritol, pentahydric alcohols such as xylitol, sorbitol, mannitol Polymers of polyhydric alcohols such as hexahydric alcohols such as diethylene glycol, dipropylene glycol, triethylene glycol, polypropylene glycol, diglycerin, polyethylene glycol and triglycerin, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether and ethylene glycol Monophenyl ether, ethylene glycol monohexyl ether, ethylene glycol isopropyl ether, ethylene glycol dimethyl ether Alcohol, alkyl ethers such as diethylene glycol monoethyl ether, diethylene glycol monobutyl ether, triethylene glycol monoethyl ether, propylene glycol monoethyl ether, dipropylene glycol ethyl ether, diethylene glycol dimethyl ether, ethylene glycol monoethyl ether acetate, diethylene glycol monoethyl ether acetate And alcohol ether esters such as propylene glycol monoethyl ether acetate and propylene glycol monopropyl ether acetate.

The higher alcohols include, for example, linear alcohols such as lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol, monostearyl glycerine ether, lanolin alcohol, hexyldecanol, isostearyl alcohol, octyldodecanol. And other branched-chain alcohols.

Examples of the high molecular compound include agar, casein, dextrin, gelatin, pectin, starch, sodium alginate, methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, nitrcellulose and crystalline cellulose as natural water-soluble polymers. Examples of the synthetic water-soluble polymer include polyvinyl alcohol, polyvinyl methyl ether, polyvinylpyrrolidone, carboxyvinyl polymer, polyethyleneimine, and sodium polyacrylate. One or more of them are used depending on the intended use.

Further, an active ingredient can be blended according to the purpose of the product. Examples of the active ingredient include a hair setting agent, a humectant, an ultraviolet absorber, an antioxidant, an antibacterial agent, and various other active ingredients.

Examples of the hair setting agent include amphoteric dialkylaminoethyl (meth) acrylate-alkyl (meth) acrylate copolymer, octylamide acrylate-hydroxypropyl acrylate-butylaminoethyl methacrylate, and the like. The union type is a vinyl pyrrolidone-vinyl acetate copolymer, a hydroxyethyl acrylate-butyl acrylate-methyethyl ethyl acrylate copolymer as a nonionic type, an alkanolamine acrylate as an anionic type, and a vinyl pyrrolidone-type as a cationic type. N, N-dimethylaminoethyl methacrylic acid copolymer sulfate, hydroxyethylcellulose / dimethyldiallylammonium chloride are available as emulsion type alkyl acrylate copolymer emulsion, alkyl acrylate Styrene copolymer emulsion and the like.

Examples of the humectant include polyethylene glycol, propylene glycol, glycerin,
1,3-butylene glycol, xylitol, sorbitol, maltitol, chondroitin sulfate, hyaluronic acid, mucoitin sulfate, caronic acid, atelocollagen,
Cholesteryl-12-hydroxystearate, sodium lactate, bile salts, dl-pyrrolidone carboxylate,
Short-chain soluble collagen, adduct of diglycerin (EO) PO, extract of Perilla, extract of St. John's wort, and extract of melilot are mentioned.

Examples of the ultraviolet absorber include benzoic acid-based ultraviolet absorbers such as para-aminobenzoic acid, and anthranilic acid-based ultraviolet absorbers such as methyl anthranilate.
Salicylic acid ultraviolet absorbers such as octyl salicylate, phenyl salicylate and homomethyl salicylate, isopropyl paramethoxycinnamate, octyl paramethoxycinnamate, 2-ethylhexyl paramethoxycinnamate, mono-2-ethyl diparamethoxycinnamate Cinnamic acid ultraviolet absorbers such as glyceryl hexanoate and [4-bis (trimethylsiloxy) methylsilyl-3-methylbutyl] -3,4,5-trimethoxycinnamate;
Dihydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, 2-hydroxy-4
Benzophenone ultraviolet absorbers such as -methoxybenzophenone-5-sulfonate sodium, urocanic acid,
Ethyl urocanate, 2-phenyl-5-methylbenzoxazole, 2- (2'-hydroxy-5'-methylphenyl) benzotriazole, 4-tert-butyl-
4'-methoxybenzoylmethane and the like.

As antioxidants, for example, ascorbic acid, α-tocopherol, dibutylhydroxytoluene, butylhydroxyanisole, etc., and as antibacterial agents, for example, benzoic acid, salicylic acid, carboxylic acid, sorbic acid, paraoxybenzoate, parachlorometa Cresol, hexachlorophen, benzalkonium chloride,
Chlorhexidine chloride, trichlorocarbanilide, photosensitizer, phenoxyethanol and the like can be mentioned.

Examples of the various active ingredients include vitamin A oil, retinol, retinol palmitate, inosit, pyridoxine chloride, benzyl nicotinate, nicotinamide, dl-α-tocopherol nicotinate,
Vitamins such as magnesium ascorbate phosphate, vitamin D ₂ (ergocasiferol), dl-α-tocopherol, dl-α-tocopherol acetate, pantothenic acid, biotin, hormones such as estradiol and ethinylestradiol, arginine, aspartic acid, Amino acids such as cystine, cysteine, methionine, serine, leucine, tryptophan, allantoin,
Anti-inflammatory agents such as glycyrrhetinic acid and azulic acid, whitening agents such as arbutin, astringents such as zinc oxide and tannic acid, refreshing agents such as L-menthol and camphor and sulfur,
Drugs such as lysozyme chloride, pyridoxine hydrochloride, and γ-oryzanol, for example, dokudami extract, oak extract, melilot extract, edulis extract, licorice extract, peony extract, sabonso extract, loofah extract, kina extract, yukinoshita extract, clara extract, kohone extract, Fennel extract, primrose extract, rose extract, jaw extract, lemon extract, sicon extract, aloe extract, shobu root extract, eucalyptus extract, horsetail extract, sage extract, thyme extract,
Tea extract, seaweed extract, cucumber extract, clove extract, raspberry extract, melissa extract, carrot extract, carrot extract, marronie extract, peach extract, peach extract, mulberry extract, cornflower extract, hamamelis extract, placenta extract, chest extract, silk Various extracts such as an extract are included. The drug can be used in a free state. In addition, a salt capable of forming a salt can be used in the form of an acid or base salt, and a compound having a carboxylic acid group can be used in the form of an ester thereof.

Examples of uses (product examples) of the water-in-oil foam aerosol composition containing the active ingredient include, for example, setting agents, treatment agents, polishing agents, matting agents, hair coloring agents, decolorizing agents and the like. Hair products; scalp products such as cleansing agents (scalp oil removal); cleansing agents, moisturizers, vitamins, whitening agents, pre (after) shave lotions,
Skin products such as astringents, sunscreens, antiphlogistic analgesics, bactericides, athlete's foot, deodorants, antiperspirants, perfumes, repellents; household products such as glass cleaners and glazes in addition to the above human body products・ Automotive supplies.

In the aerosol composition of the present invention, an oil phase containing a surfactant and an oil component, and an aqueous phase containing a water-soluble component are dispensed into a container (pressure-resistant container for aerosol), and then dimethyl ether and carbon dioxide gas are added. It can be manufactured by filling and shaking. Alternatively, the stock solution may be emulsified in advance, and then dimethyl ether and carbon dioxide may be added.

Especially limited to the aerosol pressure-resistant container
However, a commonly used container can be applied.
Also, a water-in-oil aerosol is provided in the pressure-resistant container for aerosol.
When filling the composition, for safety reasons,
8kg / cm at 35 ℃ ^Two・ It is good to be less than G
Best, 7kg / cm^Two・ Preferably less than G
New

The production method of the present invention is a method that can easily produce an aerosol composition without requiring complicated steps, and the aerosol composition obtained by the production method is a water-in-oil emulsion. Nevertheless, it forms a creamy foam with a cooling sensation (typical foamy aerosol compositions are O / W type). Further, the aerosol composition is excellent in emulsion stability, is less irritating to the skin and hair, has excellent affinity, and gives a non-sticky and refreshing feeling of use, for example, cosmetics, quasi-drugs, pharmaceuticals It can be suitably used for example.

[0047]

EXAMPLES Next, the aerosol container of the present invention and a method for maintaining the quality of an aerosol composition using the same will be specifically described based on examples, but the present invention is not limited thereto.

Examples 1 to 3 and Comparative Examples 1 to 3 7.5% by weight of isopropyl palmitate as an oil component,
7.5% by weight of jojoba oil, decaglyceryl pentaoleate as a lipophilic surfactant (Nikko Chemicals Co., Ltd.)
A stock solution was prepared from 1.0% by weight of Decaglyn 5-0, HLB 3.5) and 84.0% by weight of purified water.

The obtained undiluted solution was dispensed into an aerosol container, a valve was attached, and dimethyl ether and carbon dioxide gas were successively charged so as to have the composition shown in Table 1.
After filling, the mixture was shaken to obtain a water-in-oil aerosol composition.

The aerosol composition was filled in a transparent pressure-resistant glass bottle and evaluated by the following method.

(Ease of Emulsification) The aerosol product was shaken by hand, and the ease of emulsification was visually judged according to the following criteria. : Emulsified within 30 seconds △: emulsified within 30 to 180 seconds ×: not emulsified

(Emulsification Stability) The emulsified composition was allowed to stand at 25 ° C. and evaluated by visual observation according to the following criteria. : No separation after standing for 30 days △: Separation after leaving for 30 days, but emulsification immediately upon shaking ×: No emulsification upon shaking

(Cooling feeling) The emulsified composition is sprayed on the arm,
Evaluation was made according to the following criteria. : 90% or more of the people felt that they had a feeling of cooling △: 30 to 90% of the people felt that they had a feeling of cooling ×: Less than 30% of the people felt that they had a feeling of cooling

[0054]

[Table 1]

The compositions of the present invention (Examples 1 to 3) are excellent in easiness of emulsification, emulsion stability and cooling feeling. on the other hand,
In Comparative Example 1 containing no carbon dioxide gas, no emulsification was performed, and in Comparative Example 2 containing no dimethyl ether, no cooling sensation was obtained. In Comparative Example 3 in which the amount of the stock solution was small and the amount of dimethyl ether was large, It did not emulsify at all.

Comparative Example 4 7.5% by weight of isopropyl palmitate as an oil component
7.5% by weight of jojoba oil, decaglyceryl diisostearate (manufactured by Nikko Chemicals Co., Ltd.)
(Decaglyn 2-IS, HLB 10.0) 1.0% by weight, and a stock solution was prepared from 84.0% by weight of purified water.

88.5% by weight of the obtained stock solution was dispensed into an aerosol container, and after attaching a valve, 10% by weight of dimethyl ether and 1.5% by weight of carbon dioxide gas were sequentially filled.

In the obtained aerosol composition, since a hydrophilic surfactant having an HLB of 10 or more was used, the stock solution did not become a water-in-oil type and did not form foam.

Comparative Example 5 70% by weight of isopropyl palmitate as an oil component and decaglyceryl pentaoleate as a lipophilic surfactant (Decaglyn PR5-produced by Nikko Chemicals Co., Ltd.)
0, HLB 3.5) 2.0% by weight, and purified water
A stock solution was prepared from 0% by weight.

88.5% by weight of the obtained stock solution was dispensed into an aerosol container, and after attaching a valve, 10% by weight of dimethyl ether and 1.5% by weight of carbon dioxide gas were sequentially filled.

In the obtained aerosol composition, the amount of the oil component was large and the amount of water was small, so that the stock solution was not viscous and did not form foam.

[0062]

According to the present invention, the aerosol composition forms a stable emulsion, becomes creamy because of containing carbon dioxide gas, and has a cooling feeling water-in-oil type foam because of containing dimethyl ether. An aerosol composition can be obtained. In addition, since it is difficult to ignite even when an open flame is brought close, safety against fire is excellent.

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI theme coat ゛ (Reference) A61K 7/32 A61K 7/32 7/42 7/42

Claims (6)

[Claims] An aerosol composition comprising a stock solution and a propellant, wherein the stock solution comprises an oil component, water and a lipophilic surfactant, and the propellant comprises dimethyl ether and carbon dioxide gas. 2. A water-in-oil foam aerosol according to claim 1, wherein the stock solution comprises 0.1 to 50% by weight of an oil component, 0.1 to 10% by weight of a lipophilic surfactant and 50 to 95% by weight of water. Composition. 3. An undiluted solution of 60 to 98% by weight, dimethyl ether of 1 to 30% by weight and carbon dioxide gas of 0.01 to 10%.
The water-in-oil type foam aerosol composition according to claim 1 or 2 which is contained by weight. 4. The water-in-oil foam aerosol composition according to claim 1, wherein the lipophilic surfactant has an HLB of 9 or less. 5. The water-in-oil foam aerosol composition according to claim 1, wherein the content of dimethyl ether in the propellant is 10 to 99.7% by weight. 6. A water-in-oil emulsion comprising dispensing an oil phase containing a surfactant and an oil component, and an aqueous phase containing a water-soluble component into a container, filling with dimethyl ether and carbon dioxide, and shaking. The method for producing a water-in-oil type foam aerosol composition according to claim 1, wherein: