JP2000275249A - Automatic analyzer - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an automatic analyzer measuring item at different measuring time, capable of outputting data for each item, realizing precision control as a means of a data assurance and data evaluation control based on the measurement result of the precision control, and realizing the operation screen and printing of a system and a proper output to an external system in proper output forms. SOLUTION: This automatic analyzer can maintain the timing to isolate a specimen for measurement on measurement items required for the specimen in measuring the specimen, conducts the time control of the measurement/ calibration precision control measurement of the general specimen for each item with this timing used as a key, and can identify the mutual time relation. The zone identifier of the calibration/precision control sample measurement assuring the measurement result is calculated from the previous time control and is displayed or outputted.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an automatic analyzer for measuring the chemical and biological composition of a sample derived from a living body such as blood or urine, and more particularly to the control of quality control measurement, its display and external And the technology of data communication format.

[0002]

2. Description of the Related Art [Method of Quality Control in Automatic Analysis System] In an automatic analyzer for measuring the chemical and biological characteristics of a substance contained in a sample derived from a living body such as blood, urine, etc. The absorption principle is used as the measurement principle.

[0003] In this method, a chemical reaction and an enzymatic reaction are caused by using various reagents prepared according to an object to be measured, and a substance concentration is measured by a chemical change thereof. The resulting change in absorbance is measured over time. In the measurement of various measurement objects in the automatic analyzer, the measurement is performed by an analysis method in which various parameters such as a sample volume, a reagent volume, a reagent dispensing timing, and a reaction solution stirring timing are determined.

In actual measurement by an automatic analyzer, a sample of a known concentration is measured by the same analysis method prior to measurement of an unknown concentration sample, and the measured value actually observed by the device, that is, the absorbance or the absorbance is measured. Calibration for determining the relationship between the rate of change over time and the amount of substance is performed. In calibration, one or more substances containing a predetermined amount of the substance to be measured are prepared.

Further, when measuring a large number of unknown samples, the concentration of a specific sample is determined in order to ensure that the measurement is performed within a predetermined accuracy range for a certain period or for a certain number of samples. Quality control is performed by measuring and recording by the same analysis method. Generally, the measurement interval of the quality control sample varies depending on the measurement mode, but it is often performed for each fixed number of samples such as 50 samples and 100 samples, and when the time interval is set, the measurement is performed at intervals of 30 minutes or 1 hour. Will be However, these values and operation methods vary depending on the environment in which the measurement is placed.

[0006] The accuracy control includes all operations related to the item, that is, transport of a sample, collection and discharge of a sample, collection and discharge of a reagent, stirring of a reaction solution, measurement of change in absorbance, and data processing in general. The purpose of the present invention is to check that the processing is performed comprehensively normally by measuring under the same conditions as the actual sample.

[0007] Therefore, in this quality control, pooled sera obtained as a mixture of general specimens or specimens in which the concentration of a specific component is adjusted may be used.

In quality control, for each item,
Preferably, it is often performed at three points of general concentration, high concentration, and low concentration in an unknown sample.

The final control unit of the quality control uses each item in each apparatus, that is, the same analysis method and analysis condition. Target value of quality control sample for each measurement item,
In addition, when the quality control sample is measured, if the measured value falls within this range, it is recognized that the specified analysis has been performed correctly. ing.

[Management Method of Current Measurement Time] In a conventional automatic analyzer, a method of managing the measurement using a timing at which a specimen is identified as a key is generally used.
This is because, first, in the old days, the measurement items for each sample were uniform, and second, the time from the sample collection in the measurement to the end of measurement, that is, the timing at which data can be output, is constant. Results The method was to output the data when all the data items for the sample were collected. Third, the sample transport mode was simple, and the order of measurement was constant from sample identification to sample collection. , Etc. However, first of all, while the measurement items have been diversified, it has become necessary to measure the minimum required measurement items for each sample. As a result, a uniform measurement method is used for each sample. A method of selecting items has been adopted.

Secondly, for important items in emergency specimens, an analysis method has been developed in which the reaction time can be shortened and a reaction time such as 3 minutes or 5 minutes can be measured, which was conventionally required about 10 minutes. Became. On the other hand, an analysis method using an immune reaction has been applied to measurement of a smaller amount of a substance concentration, and an analysis method requiring about twice the reaction time of such a reaction has been developed. Thus, even within each sample, the required time from sample collection to output at which a measurement result is obtained has been different for each item.

In other words, considering a certain sample, even if data is output after the measurement result of the last sampled item has been output, if the conventional reaction time is uniform, it is substantially However, when the reaction time varies, it has become desirable to sequentially output data on the sample at the timing when the measurement result is calculated. Third, as mentioned above, the number of items has increased, and as a result of selecting and measuring items,
Since there is a difference in the number of request frequencies among the items, a method of constructing a system by combining suitable analysis units for each item has been devised. In this case, in order to operate each analysis unit more efficiently, the transport method of the sample becomes complicated, and after the part for identifying the sample, the sample is introduced into each analysis unit or transported from each analysis unit to the next analysis unit. In the process, samples pass each other, and as a result, a method of changing the order of transporting samples has been devised.

As described above, as a result of the advancement of the system,
If the time of measurement is represented by the time at the sample identification site, it is difficult to pursue a trouble or the like depending on the measurement order of the sample.

In order to deal with such troubles, in general, an automatic analyzer and its system measure the same sample at regular intervals, and make sure that the measurement is correctly performed when the results converge within a constant range. The above-mentioned method of accuracy control has been introduced. Quality control is performed, for example, when the reagent deteriorates over time to cause a decrease in sensitivity, or when a sample is collected from a sample, foreign substances are aspirated, and normal sample collection becomes impossible thereafter. In addition, it is possible to detect a trouble that occurs in the entire measurement system.

As one embodiment of this quality control, if a quality control sample at both ends of a section between measurements of a certain quality control sample is within an appropriate range, measurement of an unknown sample is performed in that section. There is a way to acknowledge that it was done correctly.

As a result of the progress of automation of the system, if predetermined preparation work for reagents, consumables, etc. is completed, the operator can automatically output data as long as the sample is erected, and the data can be output. It has become necessary to further automate the judgment and management of the operation state of the system. As a result, there has been a demand for automatic determination of data assurance by this precision management. A method of automatically performing re-measurement when it is determined that the measurement is not possible by the automatic determination is also performed. By adopting such a method, it is possible to suppress the restraint time of the operator and to shorten the time from erection of the sample to output of the data.

[0017]

SUMMARY OF THE INVENTION The present invention is intended to measure various items of measurement time, to enable data output for each item, and to perform accuracy management and accuracy management measurement performed as a means of data assurance. It is an object of the present invention to realize management of evaluation of data based on a result, and to realize an operation screen and printing of a system as an output form thereof and an appropriate output form to an external system.

[0018]

[Means for Solving the Problems] In the measurement of a sample, it is possible to hold a timing for collecting a sample for measurement for a measurement item required for the sample, and use this as a key for a general sample in item units. Performs time management of measurement, calibration, and quality control measurement, and makes it possible to identify the mutual temporal relationship.

Further, a section identifier for calibration and quality control sample measurement for guaranteeing the measurement result is calculated by the time management in the previous period, and this is displayed or output.

[0020]

DESCRIPTION OF THE PREFERRED EMBODIMENTS Embodiment 1 [Appearance and Configuration of Apparatus] FIG. 1 illustrates a system including a sample transport section and three analysis sections. The present system comprises a loading section 1 for mounting a sample, a transport section 2 for reading information attached to the sample or information provided on a member holding the sample, and transporting the sample in accordance with the information, and a sample positioned by the transport section 2. From the sample positioned by the transport unit 2 and then react with a reagent to measure the optical change thereof. A colorimetric measuring unit 5, a colorimetric measuring unit 6, and a sample collecting unit 3 that collects a sample that has undergone sample sorting.

The first colorimetric measuring section 5 is, for example, a dispensing method in which a dispensing flow path from a reagent bottle to a reaction container is provided corresponding to the reagent bottle. And the second colorimetric measurement unit 6, for example, according to the item requested from the movable reagent bottle,
A pipetting-type device that takes out a reagent and dispenses it into a reaction container can be used. Thus, in the present invention, a suitable operation screen is provided in a system in which systems of the same kind of reaction measurement system but different reagent dispensing systems are suitably combined.

In the present system, a retest buffer 7 for pooling samples from after sample collection until sample measurement data is obtained, and a transporter for re-measurement of the samples which need to be retested in the retest buffer 7. A retest line 8 for sending a sample to the unit 2 is provided.

The structure relating to the control of the present system includes a sample transport line control unit 11 for controlling a sample transport line composed of a sample input unit 1, a transport unit 2, a retest buffer 7, a retest line 8, and a sample recovery unit 3, and an electrolyte measurement unit. Measurement unit control unit 14 that controls the electrolyte measurement unit 4 that performs the measurement, and the colorimetric measurement unit 5
And first colorimetric measuring section controller 1 for controlling colorimetric measuring section 6
5 and a second colorimetric measuring section control section 16.

Further, there is provided a general control section 10 for supervising and controlling the control of the sample transport section and the three kinds of analysis sections.
The control unit controls the system.

On the other hand, the operation unit 20 comprises an operation control unit 22, a display unit 21, and an input unit 23 connected to the general control unit 10. Examples of suitable input environments for the input unit include a general keyboard, a pointing device associated with a display screen, a mouse, and a touch panel operated by touching an operation screen.

It is also desirable to use a method in which a portion to be selected is sequentially transitioned by a TAB key or an arrow key on a general keyboard and is selected by an ENTER key.

It should be noted that a personal computer which is inexpensive and has excellent operability can be used as the operation unit 20.

The system may be provided with a centrifugal separation function and an opening function as a function of opening a lid provided in the sample container, between the input section 1 and the analysis section 4 and between the other sections. .

This system is connected to the external system 30 via the general control unit 10 and the external system 3
Reference numeral 0 denotes a function for answering request information for each sample in response to an inquiry from the general control unit 10 and a system for receiving a notification of a measurement result from the general control unit 10.

It is also possible to perform substantial quality control work in the external system 30. External system 30
, A process of evaluating a measurement result and sending an instruction regarding a retest to the overall control unit 10 may be introduced.

[Summary of sample transport and measurement] The analyzer 5 can set 16 items and the analyzer 6 can set 44 items.
Here, the same measurement items as those set in the analyzer 5 may be set in the analyzer 6. However, in this case, since the analysis unit 5 and the analysis unit 6 are different in the configuration of the basic mechanism, even if the measurement items and the basic steps are the same, various analysis methods for various timings and operations are used. Will be different.

Hereinafter, the item A set in the analysis unit 5 and the item B set in the analysis unit 6 will be described.

First, for items A and B, preparation operations such as inputting or automatically recognizing a lot necessary for installing the reagent and using the reagent, and preparatory aspiration of the reagent into the channel are completed.

First, calibration is performed. As a sample for calibration,
A physiological saline is used as the concentration 0, and a sample of a known concentration is erected as a standard sample other than the concentration 0.

The rack transport and other processing steps will be described below with reference to the external view of FIG. 1 and the logical configuration diagram of FIG.

The sample is set on a rack, which is a sample transport container, and is set on the sample supply unit 1, ie, 101a. Each rack has an identifier as a rack, for example, a bar code label. It is also assumed that five samples can be placed on the rack, and the position of each can be detected by the device.

The rack is transferred to a position 111 on the main transfer line 2, ie, 123, and transferred to the identification device 103. The identification device may read an identifier attached to the rack, or may read an identifier such as a barcode attached to each sample.

In the conventional system, there is a case where the timing of specimen identification at this position is regarded as the timing of measurement. Externally, when transmitting the measurement timing of the sample, this timing may be used.
This is because sending the sample collection time of each item required for the sample to, for example, the external system 30 may significantly increase the amount of data communication.

Here, the request item for the sample is obtained from the external system 30, and the overall control unit 10 determines which of the analysis units 4, 5, and 6 is to be measured for which item. When the processing timing in each analysis unit can be specified from the timing in the sample identification unit, the sample collection timing in each unit may be calculated based on the previous sample identification time, but each analysis unit processes each item. In the case of such a system, a method for obtaining the actual measurement timing in each section is reliable.

Here, it is assumed that the calibration sample that has been installed requires sample collection in the analysis unit 5 and the analysis unit 6 as well. The rack reaching the branch point 115b checks the rack identifier at 114b via 113b. This is 1
03 for collating the read result.

Here, after it is confirmed that the predetermined rack has been transported, the sample is collected by the sample collecting section 112b.
At this time, the time of sample collection is recorded for each item. The time point may be recorded by a clock on a computer provided in the control unit 15 of the analysis unit.
May be the total number of cycles of a predetermined cycle time possessed by the analysis unit 5 from the start of the operation.

Also, the sample temporarily stored in the analyzer 5 is subjected to processing such as dilution, and then the sample is sampled again in the analyzer 5 for measurement. What is necessary is just to select the position which becomes the same order as the order in the final measurement timing. Then the rack is 115
After c is transferred to the inside of the analyzer 6 and similarly confirmed that the predetermined rack has been transferred at 114c, the sample is collected at the sample collection position 112c.

Thereafter, the rack reaches the input port of the retest buffer 7, that is, 103. Since a method such as an automatic retest is not performed on the calibration sample, the sample may be transferred to the storage unit 3 as it is.

Next, following the measurement of the calibration sample, the measurement of the first quality control sample is performed. For a general sample, the same processing is performed for determination of the sample transport path and measurement. However, the transport path of the sample differs depending on the items required for the sample.

[Processing Flow] Referring to FIG. 9, a processing flow in the present invention will be described. The system 900 includes a sample transport management 911 and a measurement result management unit 9 by the overall control unit.
20. Here, the sample transport management unit 911
Then, the erected samples are analyzed by predetermined analysis units 914, 915, 9
It is conveyed to any one or a plurality of 16 and analysis is started. When the analysis is performed, the measurement result is transmitted to the measurement result management unit 920 together with the timing at which the sampling is performed from each analysis unit, and the management of the measurement order and the relationship between the quality control measurement and the general measurement are determined. You.

According to this relationship, the measurement result is displayed on the measurement result display section 921 as described later. In addition, the measurement result is transmitted to the external information processing unit 930 via the measurement result transmission unit 925 as described later.

[Principle of Accuracy Management in Single Item] The accuracy management method in the present invention will be described when focusing on a single item.

FIG. 3 shows the relationship of the measurement order. FIG. 3 shows the relationship between the processing status of each sample with the sample number on the horizontal axis and the time on the vertical axis.

First, a standard sample C1 to be calibrated is installed, and the system performs sample identification. This timing is defined as tci1. Focusing on this sample, the time after the transport time 301
A sample is collected at tc1 and data is output after a reaction time 302. The system management sample 1Q1 following this sample is the time
The sample is identified at tqi1, and the sample is collected at time tq1. For the same items in the same analysis unit, no change occurs in the order after the time of sample collection, and therefore, in this embodiment, the time of sample collection is used as a key as described above. Quality control sample 1Q1
General sample 1R1 to general sample 6R to be sampled thereafter
Then, the quality control sample 2Q2 is sampled at time tq2.

Here, at time tq1 shown in FIG.
In the case where the measurement results of the quality control samples 1Q1 and 2Q2 are within a predetermined range, it is determined that the general samples sampled at a time point tq2 are within the range of the quality control.

Here, for example, for the general sample 3R3, the time of sample identification is before the calibration sample, but even in this case, at the time of sample collection, the sample is the fair sample and the quality control sample 1Q1 or later. Q1 and Q as areas
2 (A).

When the data of Q1 is output at time tqd1, the measurement of the quality control sample for Q1 is evaluated, and if it is within the allowable range, the samples after R1 are controlled at least at the starting point of the quality control section. Can be output, and data can be output. Strictly, data is output at time tqd2, and at the time of evaluation, data in the section (A) can be guaranteed.

FIG. 4 shows the relationship of section setting. Here, each time point is the time point of sample collection, and a single item will be described.

Measurement start time 401, calibration sample measurement 411
Subsequently, the quality control sample (1) is measured 421. From this, one or more general samples were measured, and 431-4
32. The quality control sample is measured again as the quality control sample measurement (2) 422, and the section (A) is determined. 421 and 42
When the measurement of No. 2 is within a predetermined allowable range, the general sample measurement of 431 to 432 is validated. The measurement 422 of the quality control sample measurement (2) also means the starting point of the next section, and the section (B) is determined by the quality control sample measurement (3) 423.

[Screen Display] Next, the section display by the accuracy control will be described with reference to FIG. 5, taking a measurement result screen for a single sample as an example. Although the measurement results of the entire system are not shown in the figure, it is assumed that a list is displayed for each sample, the sample is selected, and the measurement result display of FIG. 5 is displayed as a detailed display.

The sample number, sample I
An attribute such as D that can easily identify the sample is displayed. Here, information such as the patient name, age, and disease name of the sample may be displayed. It is displayed that the measured value corresponding to the measurement item is useful for the sample.

Measurement result 502 for measurement item 501 g
g is displayed and the data alarm 5 for the measurement item is displayed.
03g is displayed.

Here, the data alarm "B" indicates that the section determination by the quality control sample is not completed.

The state 504g at the start of the section indicates that it is within the allowable range, and then the section number 505g of the item is displayed. The section number may be a continuous number in a certain period. For example, in this embodiment, the section number is described as the seventh section on the day of the measurement day. Also, the state 506g of the measurement result of the quality control sample at the end of the section is displayed. Here, it is displayed that the measurement result of the quality control sample at the end of the section has not been obtained yet.

As described above, by displaying the quality control section for each item, it is possible to easily recognize the status of the quality control.

As the measurement time point of the specimen, the specimen identification time point may be used as before, or only the accuracy control may be performed by such a method.

In the present embodiment, the measurement results are obtained at the time when the request is confirmed, then at each time when the sample of the quality control sample at both ends of the quality control section is collected, and further, the measurement result of the unknown sample is obtained. It is assumed that the screen is updated successively at each time point and when each result of the quality control sample is obtained.

[Communication Format] Next, a description will be given of a format for notifying a measurement result to an external system as an example of output in this embodiment with reference to FIG.

Generally, in the communication function, when the analysis system identifies a sample, the key information identifying the sample is transmitted to the external system, and the measurement request information is transmitted as an answer by the external system. Although there is a function, here, the function of transmitting the measurement result will be limited and described.

The transmission format of the measurement result includes a start unit 601 and sample attribute information 601a. The sample attribute information includes information for identifying the sample such as a sample number and a sample ID, and information about the sample such as a name. Further, information on the item requested for the sample is also included. Subsequently, item data (1) 601b to item data (n) 601c are sequentially included for each item. After the information on all items, the transmission format is closed with the end 601d. Each item data has a sequence 602 indicating the number of the item measured in the sample.
a, item code 602b specifying the item, measured value 602
c, a measurement value unit 602d, an alarm code 602e related to the measurement value, and a data section 60 indicating measurement conditions and the like.
2f. Further, a measurement start time 602g and a measurement end time 602h are included.

The measurement start time may be defined at the time of sample identification or sample collection, and the measurement end time may be defined at the time of data output. The gist of the present invention is the next quality control section.
602i and the quality control state 602j. As shown in the previous screen, the quality control section may be a sequential number for a certain period. As the accuracy management state, as described in the screen, a code may be used to indicate that the start of the section is within the allowable range, the end of the section is within the allowable range, and the like. If the specification of the numbering method is determined, the external system side does not need to be aware of the device configuration and item arrangement, etc. Can be identified.

FIG. 7 shows a data output method.

Data evaluation is started for each item (70).
1) First, the section start of the quality control sample is evaluated (702). When the evaluation result is good, the unknown sample sample measurement result evaluation (703) is performed. If the quality control sample measurement is out of the allowable range at the start of the section, stop the measurement on the channel, or if measurement is taking place, follow the measurement results of the quality control sample and the unknown sample in the section. Add an alarm.

In the evaluation of the measurement result of the unknown sample (703), if the measurement result is OK, if there is an alarm, an alarm is added, and the measurement result is set to the sequential (real-time) transmission mode and the external system (704). This is to respond to the need to obtain data as soon as possible, such as on the clinical side.

Next, the measurement result of the quality control sample at the end of the section is evaluated (705).

In this case, if there is no problem in the section, an alarm is added if there is a problem, and the item of the unknown sample in the quality control section of the item is judged at once. To put it together (batch)
Mode to the external system. In external systems,
This information is overwritten on the information obtained by the sequential (real-time) transmission previously obtained, and when it is determined that there is a possibility that the measurement result may have a significant inconvenience, a process of notifying the user is performed. (Not shown).

In this way, it is possible to guarantee the data by the quality control measurement accurately in the external system and without adding the judgment logic in the external system.

(Embodiment 2) [Judgment of re-inspection] FIG. 8 shows a method of judging whether or not to perform re-inspection.

In the case where the quality control is performed by the method shown in the first embodiment, the case where the quality control itself is not established and the case where the quality control is correctly performed but the measurement of the unknown sample is not within the allowable range are performed. Divided.

At the start of reexamination determination 801, it is first determined 802 that the accuracy control is within the allowable range at the start of the section, and it is determined 803 that the quality control is within the allowable range at the end of the section. Is determined 804 according to the criterion of sample measurement. As this method, there is a method of determining that the sensitivity is within the sensitivity of the measurement system.

If both are within the allowable range, it is determined that there is no retest.

If there is a problem with the accuracy control, the retesting feasibility is evaluated 805.

The evaluation of the re-test feasibility is based on the fact that if there are a plurality of measurable channels for the same item in the system, for example, if the same measurement item is arranged to be measurable in parallel with a plurality of analyzers, By using a channel that was not used for measurement, or by an automatic washing function, for example, if a clogging occurs in the sample collection mechanism, if there is a way to recover by removing it, there is a possibility of retesting, It is determined that it is possible. If there is no such possibility, the automatic retest will not be performed.

If there is no problem in the accuracy control and there is a problem in the measurement of the unknown sample, for example, when the concentration is large and an error occurs, re-analysis is performed by a method such as an analysis method in which the sample volume is reduced. By doing so, data may be obtained, and in this case, it is determined that retesting is feasible. When it is determined that the retest is feasible, the refeed is supplied from the retest buffer 7 in FIG. 1 to the main transport line 2 via the retest line 8, and the measurement is performed again under appropriate conditions.

There is also a method of retesting the quality control sample itself, but when it is difficult to automatically restore the state of the apparatus, the quality control sample is not automatically retested and another channel is used. The method is highly feasible.

(Embodiment 3) Here, a case will be described in which the order of measurement of a plurality of samples is measured by each measurement unit regardless of the order in which they are installed in the apparatus.

In a simple manner, for example, when a plurality of samples are installed at one time, the samples are transported to each sample sorting mechanism according to the order of installation, and the samples are sampled and measured sequentially.

However, in a system having a plurality of measurement units, for example, when the same item is measured at a plurality of locations, any one of the plurality of measurement units is selected and measured. There is an analysis unit that does not contribute to the measurement of.

In this case, the transfer to the analysis section which does not contribute to the measurement necessarily requires an unnecessary transfer operation for the processing of the whole system when the transfer capacity of the sample is limited, and as a result, This results in a reduction in the processing capacity of the entire system.

Therefore, in this case, it should not be conveyed to the measuring section which is not necessary for the measurement. As a result, for example, a sample that needs to be measured by both the second measuring unit 15 and the third measuring unit 16 is installed on the first rack, and the sample is measured only by the third measuring unit 16 on the next rack. In the case of the sample transport mechanism shown in FIGS. 1 and 2, when the sample is completed in the system, the first rack position 101a and the second rack position 1
Despite the order of 01b, the second rack may be transported to the third measuring unit 16 prior to the first rack. In this case, in the quality control sample in which the order relation is important, the determination of the measurement order means that the measurement order does not change when viewed from the sample sampling positions 112b and 112c in the measurement mechanism and the positions.
13b, 114b, 112b or 113c, 114
c, 112c.

Therefore, in the system of such a system, by managing the sampling position or the order selected within a range in which the measurement order does not change when viewed from the sampling position, or the time, the accuracy management which results in the section management is performed. Can be realized.

[0087]

According to the present invention, the relationship between the timing of measurement and calibration of a quality control sample can be tracked for each item of each measurement section, so that the measurement of an unknown sample can be performed based on the calibration at any time and at what accuracy. It is possible to easily identify whether it is guaranteed by the control sample measurement. Further, according to the present invention, automatic retesting that reflects the state of quality control becomes possible.

[Brief description of the drawings]

FIG. 1 is a system configuration diagram.

FIG. 2 is a diagram showing a logical configuration.

FIG. 3 is a diagram showing a relationship of a measurement order.

FIG. 4 is a diagram showing a relationship of a measurement order.

FIG. 5 is a diagram showing a measurement result display screen.

FIG. 6 is a diagram showing a communication format.

FIG. 7 is a diagram illustrating a data output method.

FIG. 8 is a diagram illustrating a retest execution determination.

FIG. 9 is a processing block diagram.

[Explanation of symbols]

DESCRIPTION OF SYMBOLS 1 ... Sample input part, 2 ... Transport part, 3 ... Sample collection part, 4 ... Electrolyte analysis part, 5, 6 ... Colorimetric measurement part, 7 ... Retest buffer,
8 ... Retest line.

 ──────────────────────────────────────────────────続 き Continuing on the front page (72) Inventor Kazumitsu Kawase, 882-Momo, Oaza-shi, Hitachinaka-city, Ibaraki Pref., Ltd.Measurement Division, Hitachi, Ltd. F-term in Hitachi Instruments Measuring Instruments Division (reference) 2G058 AA05 AA08 CB08 CB09 CB15 CD04 CE08 GA01 GC02 GD01 GD03 GD06 GE02

Claims (8)

[Claims] 1. An automatic analyzer that can select and measure a plurality of items required for each sample from measurement items prepared in advance in the device, and a time when samples are collected for each item to be measured. Or means for storing the timing of the processing step so as to be able to specify the time at which the sample was collected, and means for specifying the time at which the sample was collected based on the stored timing. An automatic analyzer comprising means for performing time management of sample measurement and calibration or quality control based on the sample. 2. An automatic analyzer in which a plurality of items required for each sample can be selected and measured from measurement items prepared in advance in the device. In the case where a plurality of homologous sites capable of measuring the sample are provided, means for storing the time at which the sample is collected for each site, or the timing of the processing step is stored so that the time at which the sample is collected can be specified. Automatic means provided with means for specifying the time at which the sample was collected based on the stored timing, and means for performing time management of sample measurement and calibration or quality control based on the specified collection time. Analysis equipment. 3. A method for measuring a quality control sample of a first group and a measurement result of an unknown sample sandwiched between a measurement of a quality control sample of a second group and a measurement of an unknown sample between the second group. The automatic analyzer according to claim 1, wherein an identifier capable of specifying that the sample is sandwiched between the quality control samples is displayed or output. 4. The method according to claim 1, wherein a time at which a sample is collected is specified for an unknown sample between the measurement of the first group of quality control samples and the measurement of the second group of quality control samples. An automatic analyzer, wherein the identified measurement result, the state related to the measurement result of the first group of quality control samples, and the state related to the measurement result of the second group of quality control samples are displayed on the screen in a distinguishable manner. 5. The method according to claim 1, wherein a time at which a sample is collected is specified for an unknown sample between the measurement of the first group of quality control samples and the measurement of the second group of quality control samples. The identified measurement result, the state related to the measurement result of the first group of quality control samples, and the state related to the measurement result of the second group of quality control samples are output as a printout or an electrical signal so as to be identifiable. A featured automatic analyzer. 6. A state relating to a measurement result of the first group of quality control samples, wherein the measurement result of the unknown sample interposed between the measurement of the first group of quality control samples and the measurement of the second group of quality control samples, The automatic analyzer according to claim 1, wherein a measurement result of the unknown sample is evaluated from a state related to the measurement result for the quality control sample of the second group, and the evaluation result is displayed or output so as to be identifiable. . 7. A state relating to the measurement result of the first group of quality control samples, wherein the measurement result of the unknown sample sandwiched between the measurement of the first group of quality control samples and the measurement of the second group of quality control samples is: From the state related to the measurement result for the quality control sample of the second group, the measurement result of the unknown sample is evaluated, and when the evaluation result is not within the predetermined determination reference range, the quality control can be correctly performed for the item. 3. The automatic analyzer according to claim 1, wherein the unknown sample is automatically measured again when there is a possibility. 8. An analysis system for transporting and measuring a sample between the plurality of measuring units each having a sample collecting mechanism and measuring the sample from a place where the sample is installed. When the transport order up to sample collection for the sample collection is not fixed, the sample collection mechanism in each measurement unit has a means for storing the sample collection time, and the time selected by such means or the corresponding information And means for storing the measurement results together, and when evaluating the measurement results by comparing them with the measurement results of a known concentration, determine the measurement order based on each measurement result and the time or the corresponding information. A method of managing measurement results, characterized in that the measurement results are managed.