JP2000167022A - Double-room medical container - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a double-room medical container which can be easily manufactured, which can be securely sealed and separated without breaking the sealed part with a pressure to be applied in the manufacturing process, transportation process or in storing, and whose rooms can be made to communicate with each other by a simple operation when used. SOLUTION: This is a flexible container 1 with plural sections, and a medicine is stored and sealed in each section. Each section is made to communicate with each other with a communicating member 4 with a sealed part whose sealing is easily broken by pressure from outside.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a multi-chamber medical container used for drip injection and the like. More specifically, a liquid for dilution or dissolution (in the present invention, referred to as "liquid drug") and another drug (in the present invention, used by mixing or dissolving in a liquid drug) The other drug is referred to as “another drug.” A liquid drug (preferably a liquid drug) is sealed and stored in a sealed state, and these drugs are kept separated during transportation and storage, and the communication member is sealed when used. The present invention relates to a multi-chamber medical container capable of easily dissolving or mixing these drugs with a simple operation by breaking a stop portion.

[0002]

2. Description of the Related Art Intravenous injections are widely used in the medical field.
Infusion may be performed by mixing two or more drugs. For example, when mixing and infusing liquid medicines, these medicines are sufficiently mixed and used for infusion as an infusion.In such a case, the mixing operation is usually performed in an environment such as an examination room or a hospital room. To be carried out,
There is concern about the possibility of invasion of various bacteria.

[0003] For the purpose of avoiding such danger, various two-drug infusion containers having sanitary epidemiological properties have been developed. For example, the inner wall surface of a bag-shaped container formed of a synthetic resin film is fused and partitioned, divided into a plurality of chambers, and a chemical solution for mixing is stored in each room, and the partition is used when a chemical solution for infusion is required. There is known an infusion container that allows a plurality of chemical solutions to be mixed in an aseptic environment by opening and fusing a fusion portion of the container and communicating the entire bag-shaped container. Until the infusion container is used, it is necessary to surely separate the stored and separated medical solutions until the infusion is performed. Therefore, the normal handling process required for the infusion container, such as washing, dispensing, sterilization, etc. The fusion part should not be something that easily peels off, but when mixing each separated chemical solution, without breaking the infusion container itself, and furthermore, only the separation partition fusion part is separated or It is required to be able to be broken and integrated.

As an infusion container for satisfying these requirements, there are various methods, for example, a method in which the isolation means is thermally bonded (Japanese Patent Application Laid-Open Nos. 63-19149 and 1-2404).
No. 69, etc.) and a thermal bonding method using a resin mixture (Japanese Patent Application Laid-Open No. 2-4671). However, the infusion container according to the above method involves considerable difficulty in adjusting and maintaining the adhesive strength of the isolation portion within a desired strength range in the manufacturing process, and subsequent container washing, dispensing, or high-temperature sterilization. There is a problem that the separation part may be partially peeled in the process.

[0005]

SUMMARY OF THE INVENTION The present invention has been made in view of such a problem, that is, it is easy to manufacture, and a chemical solution stored in each room before use is manufactured in a process for manufacturing a multi-chamber medical container. The object of the present invention is to provide a multi-chamber medical container which can be securely sealed and separated without breaking the sealing part even at a pressure which would normally be applied in the transportation process, storage, etc., and which can be connected by a simple operation in use. And

[0006]

Means for Solving the Problems The present invention relates to [1] a flexible container which is divided into a plurality of compartments and in which a medicine is stored in a sealed state inside each compartment, wherein a space between each compartment is provided. A multi-chamber medical container, wherein the communication member has a sealing portion that is easily broken by external pressure, and the communication member has a sealing portion on one end surface. The double-chamber medical container according to the above [1], which is a formed cylindrical body, and [3] a sealing portion,
A cylindrical member of a communicating member, which is formed by a thick fulcrum portion serving as a fulcrum when breaking the seal and a peripheral portion made of a thin wall that is cut off, and a projection projecting from the thick fulcrum portion at a position facing the thick fulcrum portion The object has been achieved by developing the multi-chamber medical container according to the above [1] or [2], which is a plate material.

[0007]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The contents of the present invention will be described below in detail with reference to the drawings. FIG. 1 is an overall view showing an example of the multi-chamber medical container of the present invention. In FIG. 1, a flexible container 1 is a flexible container capable of separately storing a plurality of drugs including a liquid drug, preferably a liquid drug as a whole, and is transparent for confirming contents. It is composed of a material having heat resistance and heat resistance for retort sterilization. Preferred materials include a single polyolefin film, a laminated film of two or more polyolefins, a laminated film of a polyolefin and another synthetic resin, and the like.

Although there is no particular limitation on the method of manufacturing the flexible container 1, for example, a cylindrical film obtained by single-layer or multi-layer inflation molding, which is generally used in plastic molding, is cut to form upper and lower and partition walls. A method of performing thermal welding, a method of folding a film obtained by T-die molding or lamination molding into two, and superposing and thermally welding a peripheral portion and a partition wall may be used. At least one of the drugs used in the multi-chamber medical container of the present invention must use a liquid drug. Examples of the liquid drug include physiological saline, glucose solution, distilled water for injection, and various other electrolyte-containing solutions. The other drug is not particularly limited, but is preferably a liquid drug.

A bottom portion of the flexible container 1 is usually closed with a rubber stopper 21 and is provided with a port member 2 for filling and taking out, which is obtained by injection molding using polyolefin as a main material. 3 is adhered. At this time, it is advantageous in terms of cost and performance to use heat welding for bonding the mouth member 2. The partition by the partition at the center of the flexible container 1 is usually performed by heat welding. However, in order to secure the communication between the upper and lower partitions, at least one partition manufactured by injection molding using polyolefin as a main material is used for the partition. The communication member 4 having the sealing portion 5 is bonded to the heat-welded portion 3 of the tubular film.
Also in this case, heat welding is advantageous in cost and performance. The shape of the communication member can be freely selected, such as a circular, elliptical or rectangular cross section. In the upper and lower sections, the communicating members are arranged so that the inside of the flexible container finally becomes one infusion container through these communicating members. FIG. 1 shows two multi-chamber medical containers provided in series, but a multi-chamber medical container provided in series and divided into three units as shown in FIG. 2 may be used. Alternatively, sections other than the section provided with the take-out port member may be divided in parallel. It is not necessary to limit the size of each section provided with the ejection port member, but it is preferable that the section be capable of accommodating all the medicines filled in the multi-chamber medical container in this section.

FIG. 3 is an enlarged view of the communication member 4. In FIG. 3, the sealing portion 5 includes a projection 51 serving as a point of force at the time of pressurization, a thin peripheral portion 52, and a thick fulcrum 53 having a small width. FIG.
3A is a perspective view of the communication member, FIG. 3B is a cross-sectional view for clarifying the shape of the sealing portion, and FIG. 3C is a diagram in which the sealing portion of the communication member is broken to communicate. Indicates the status. The thickness of the thin peripheral portion is preferably 0.02 mm to 0.3 mm, and particularly preferably 0.1 to 0 mm in consideration of natural communication prevention or breaking force, so that the thin peripheral portion 52 is easily broken by pressing the projection 51. .2 mm is preferred. In use, when the protrusion 51 is pressed by a finger or the like, the thin peripheral portion 52 is torn and the thin peripheral portion 52 is left open, leaving the thick fulcrum 53. Sealing member 5
May be any of a circle, an ellipse, a rectangle, and a polygon. The sealing section 5 has a relatively small cross-sectional area, so that when a multi-chamber medical container is stacked for transportation or storage, or when pressure is applied to a section containing a liquid drug in some time, the pressure is the same as a whole. Although it is applied with strength, the small area of the sealing portion works advantageously, and it is easy to make it safe against normal handling and stacking pressure. Further, when the container capacity is large and the cross-sectional area of the communication portion needs to be increased, a plurality of communication portions are provided, or two or more sealing portions as shown in FIGS. 4A and 4B are provided. It is preferable to use a communication member having the same.

The method of filling the multi-chamber medical container is not particularly limited. For example, the cylindrical film is divided into a plurality of pieces by heat welding with a mouth member at the lower end and a communication member inside the film. Next, the upper chamber is filled with a drug, and the upper end is sealed by heat welding. Then, another drug is charged into the lower chamber from the mouth member and sealed with a rubber stopper to complete the multi-chamber medical container. At the time of use, the projection of the sealing portion of the communication member is pushed through the film of the flexible container to break the peripheral thin portion, and the two sections are communicated with each other. Mix. If the whole is a liquid drug,
When the section provided with the take-out member has a large volume and can accommodate the entire medicine, it is preferable to collect, mix and use the entire medicine in that section.

[0012]

According to the multi-chamber medical container of the present invention, the sealing portion is not broken even by a slight pressurization after filling the liquid medicine, so that each liquid medicine can be reliably isolated until immediately before use. At the time of use, the medicines filled in the multi-chamber medical container can be easily and surely mixed while maintaining the aseptic state by a simple operation of pushing the projection 51.
Further, since all the constituent materials are plastic, the container is a multi-chamber medical container excellent in disposability.

[Brief description of the drawings]

FIG. 1 is an overall sectional view showing an example of a multi-chamber medical container of the present invention.

FIG. 2 is an overall sectional view showing another example of the multi-chamber medical container of the present invention.

FIG. 3A is an enlarged perspective view of a communication member. (B) An enlarged sectional view of a sealing part. (C) A perspective view showing a state in which the sealing portion is broken.

FIG. 4A is an enlarged perspective view of a communication member. (B) A perspective view showing a state where the sealing portion is broken.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Flexible container 2 Port member 21 Rubber stopper 3 Heat welding part 4 Communication member 5 Sealing part 51 Projection part 52 Peripheral thin part 53 Thick fulcrum part 6 Hanging hole

Continued on the front page (72) Inventor Akihiko Sakata 3-2-2 Chidoricho, Kawasaki-ku, Kawasaki-ku, Kawasaki, Kanagawa Prefecture Inside the Showa Denko KK Kawasaki Laboratory (72) Inventor Manabu Nakamura 3, Chidoricho, Kawasaki-ku, Kawasaki-shi, Kanagawa (Showa Denko Co., Ltd.) Kawasaki Lab. (72) Inventor Junji Yotsuyanagi 3-2-2 Chidori-cho, Kawasaki-ku, Kawasaki City, Kanagawa Prefecture Showa Denko Co., Ltd. Kawasaki Lab.

Claims (3)

[Claims] 1. A flexible container which is divided into a plurality of sections and in which a medicine is stored in a sealed state inside each section, wherein a seal between the respective sections is easily broken by external pressure. A multi-chamber medical container characterized by being able to communicate with a communication member having a sealing portion. 2. The double-chamber medical container according to claim 1, wherein the communication member is a cylindrical body having a sealing portion formed on one end surface. 3. The sealing portion includes a thick fulcrum portion serving as a fulcrum when the seal is broken, a peripheral portion made of a thin portion to be cut off, and a projection projecting at a position facing the thick fulcrum portion. ,
The double-chamber medical container according to claim 1, wherein the medical container is a plate member that seals a cylindrical body of the communication member.