ITTO980264A1 - APPLICATION OF A NON-QUATERNARY BASIC EXTRACT OF FUCHSIAEFOLIA PESCHIERA WITH ANTI-MALARICA ACTIVITY - Google Patents

APPLICATION OF A NON-QUATERNARY BASIC EXTRACT OF FUCHSIAEFOLIA PESCHIERA WITH ANTI-MALARICA ACTIVITY Download PDF

Info

Publication number
ITTO980264A1
ITTO980264A1 IT98TO000264A ITTO980264A ITTO980264A1 IT TO980264 A1 ITTO980264 A1 IT TO980264A1 IT 98TO000264 A IT98TO000264 A IT 98TO000264A IT TO980264 A ITTO980264 A IT TO980264A IT TO980264 A1 ITTO980264 A1 IT TO980264A1
Authority
IT
Italy
Prior art keywords
peschiera
activity
application
fuchsiaefolia
malarica
Prior art date
Application number
IT98TO000264A
Other languages
Italian (it)
Inventor
Silvio Rossi
Motta Giuseppe Bertelli
Original Assignee
Silvio Rossi
Motta Giuseppe Bertelli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Silvio Rossi, Motta Giuseppe Bertelli filed Critical Silvio Rossi
Priority to IT98TO000264A priority Critical patent/ITTO980264A1/en
Priority to JP2000537549A priority patent/JP2002507570A/en
Priority to CA002325879A priority patent/CA2325879A1/en
Priority to APAP/P/2000/001926A priority patent/AP2000001926A0/en
Priority to EP99907808A priority patent/EP1067938A1/en
Priority to PCT/IB1999/000524 priority patent/WO1999048501A1/en
Priority to AU27427/99A priority patent/AU2742799A/en
Priority to BR9909153-4A priority patent/BR9909153A/en
Publication of ITTO980264A1 publication Critical patent/ITTO980264A1/en
Priority to OA1200000261A priority patent/OA11491A/en
Priority to ZA200006020A priority patent/ZA200006020B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Compounds Of Unknown Constitution (AREA)

Description

Applicazione di un estratto basico non quaternario dalla PESCHIERA Fuchsiaefolia ad attività antimala= Application of a non-quaternary basic extract from PESCHIERA Fuchsiaefolia with antimala activity =

rica; ric;

La presente invenzione ha per oggetto l'applicazione dell'estratto basico non quaternario della Pianta The present invention relates to the application of the non-quaternary basic extract of the Plant

calssifinata con il nome botanico Peschiera Fuchsiae folia, raccolta in Brasile. Porto Alegre Rio do SouL ed identificata dalle Cibecol Industria Farmaceutica La corteccia della Peschiera F. è stata fatta perveni— calssifinata with the botanical name Peschiera Fuchsiae folia, collected in Brazil. Porto Alegre Rio do SouL and identified by Cibecol Industria Farmaceutica The bark of the Peschiera F.

re dai fiduciari re by the trustees

effettuarne l’estrazione dei principi attivi denominati Alcaloidi terziari. carry out the extraction of the active ingredients called tertiary alkaloids.

sono eluiti nell'ordine la PEVERINA PEVERINA are eluted in order

(pu= rificati per ulteriore separazione per DCC a riciclo e poi l'AFFINISINA. sono eluiti (purified for further separation by recycling DCC and then AFFINISIN. are eluted

e la rificati per DCC a riciclo, e successivamente a pH3,2 sono eluiti La VOACALOTIKA e la VOACAMINA and the rified for DCC for recycling, and subsequently at pH3,2 the VOACALOTIKA and the VOACAMINA are eluted

purificati per riciclo. sono stati separati anche per successivo riciclo la CONOFARINGINA (2.10 ) la CORONARIDINA e la VOACANGI S purified for recycling. CONOPHARINGIN (2.10), CORONARIDIN and VOACANGI S were also separated for subsequent recycling

MA BUT

L'insieme di questi alcaloidi così ottenuti sono stati inviati all'Organizzazione Mondiale di Sanità D.M.S. per le prove in vitro sul Plasmodium Palcipa All these alkaloids thus obtained were sent to the World Health Organization D.M.S. for in vitro tests on Plasmodium Palcipa

rum(l 'agente» patogeno della malaria) per le prove di laboratorio . rum (the pathogen of malaria) for laboratory tests.

T dati risultanti da queste prove sono la comprova dell 'attività antimalarica dell'estratto, dimostrato dal commento dello screener "YESYES". The data resulting from these tests are proof of the antimalarial activity of the extract, demonstrated by the comment of the screener "YESYES".

Claims (1)

RIVENDICAZIONI Si rivendica che l'estratto ottenuto con la metodo= logia descritta,ha efficacia sul Plasmodium Falcipa= rum e quindi usato puro o diluito nelle percentuali, descritte ed esemplificate nell'allegata documenta zione sia nella forma liquida per uso orale, sotto= cutanea, parenterale, per inalazione, per osmosi, per diluizione omeopatica, sia nella forma solida, per uso orale per inalazione, osmosi, ed in forma Omeopatica. venga tutelato dal presente atto. 1' efficacia dell' estratto secondo la rivendicazione I ha effetto sia per la profilassi che per la cura della malaria. CLAIMS It is claimed that the extract obtained with the described method is effective on Plasmodium Falcipa = rum and then used pure or diluted in the percentages described and exemplified in the attached documentation both in the liquid form for oral, subcutaneous, parenteral use, for inhalation, for osmosis, for homeopathic dilution, and in the solid form, for oral use by inhalation, osmosis, and in shape Homeopathic. is protected by this deed. The efficacy of the extract according to claim 1 is effective for both prophylaxis and treatment malaria.
IT98TO000264A 1998-03-26 1998-03-26 APPLICATION OF A NON-QUATERNARY BASIC EXTRACT OF FUCHSIAEFOLIA PESCHIERA WITH ANTI-MALARICA ACTIVITY ITTO980264A1 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT98TO000264A ITTO980264A1 (en) 1998-03-26 1998-03-26 APPLICATION OF A NON-QUATERNARY BASIC EXTRACT OF FUCHSIAEFOLIA PESCHIERA WITH ANTI-MALARICA ACTIVITY
JP2000537549A JP2002507570A (en) 1998-03-26 1999-03-25 Vocamin as antimalarial and antimalarial containing vocamin
CA002325879A CA2325879A1 (en) 1998-03-26 1999-03-25 Voacamine as anti-malarial agent and anti-malarial agent containing voacamine
APAP/P/2000/001926A AP2000001926A0 (en) 1998-03-26 1999-03-25 Voacamine as anti-malarial agent and anti-malarial agent containing voacamine.
EP99907808A EP1067938A1 (en) 1998-03-26 1999-03-25 Voacamine as anti-malarial agent and anti-malarial agent containing voacamine
PCT/IB1999/000524 WO1999048501A1 (en) 1998-03-26 1999-03-25 Voacamine as anti-malarial agent and anti-malarial agent containing voacamine
AU27427/99A AU2742799A (en) 1998-03-26 1999-03-25 Voacamine as anti-malarial agent and anti-malarial agent containing voacamine
BR9909153-4A BR9909153A (en) 1998-03-26 1999-03-25 Voacamine as an antimalarial agent, and antimalarial agent that contains voacamine
OA1200000261A OA11491A (en) 1998-03-26 2000-09-22 Voacamine as anti-malarial agent and anti-malarialagent containing voacamine.
ZA200006020A ZA200006020B (en) 1998-03-26 2000-10-26 Voacamine as anti-malarial agent and anti-malarial agent containing voacamine.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT98TO000264A ITTO980264A1 (en) 1998-03-26 1998-03-26 APPLICATION OF A NON-QUATERNARY BASIC EXTRACT OF FUCHSIAEFOLIA PESCHIERA WITH ANTI-MALARICA ACTIVITY

Publications (1)

Publication Number Publication Date
ITTO980264A1 true ITTO980264A1 (en) 1999-09-26

Family

ID=11416637

Family Applications (1)

Application Number Title Priority Date Filing Date
IT98TO000264A ITTO980264A1 (en) 1998-03-26 1998-03-26 APPLICATION OF A NON-QUATERNARY BASIC EXTRACT OF FUCHSIAEFOLIA PESCHIERA WITH ANTI-MALARICA ACTIVITY

Country Status (10)

Country Link
EP (1) EP1067938A1 (en)
JP (1) JP2002507570A (en)
AP (1) AP2000001926A0 (en)
AU (1) AU2742799A (en)
BR (1) BR9909153A (en)
CA (1) CA2325879A1 (en)
IT (1) ITTO980264A1 (en)
OA (1) OA11491A (en)
WO (1) WO1999048501A1 (en)
ZA (1) ZA200006020B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812199A1 (en) * 2000-07-31 2002-02-01 Maximun Frederic Yanze Effervescent antimalarial compositions containing chloroquine, optionally other active agents, effervescent couple and taste modifiers, is dissolved in water to give a pleasant tasting solution for oral administration
EP1491197A1 (en) * 2003-06-26 2004-12-29 Bertelli Motta, Guiseppe Pharmaceutical composition comprising voacamine for the stimulation and modulation of the human immunologic system
US20070232588A1 (en) * 2004-09-15 2007-10-04 Leonard Stella Anti-parasitic and/or anti-viral and/or anti-microbial compositions
US20070032460A1 (en) * 2005-08-04 2007-02-08 Leonard Stella Use of voacamine and related compounds in the treatment of malaria
CN101282956B (en) 2005-10-04 2013-03-20 防卫研究与发展组织总干事 Anti-malarial compound isolated from gomphostema niveum
EP1958638A1 (en) 2007-02-14 2008-08-20 Polichem S.A. Use of chitosans to increase nail growth rate
US20140303148A1 (en) 2011-11-28 2014-10-09 Industry-Academic Cooperation Foundation, Yonsei University Pharmaceutical compositions for inhibiting angiogenesis comprising plant-derived natural compound
US9783535B2 (en) 2012-12-20 2017-10-10 Demerx, Inc. Substituted noribogaine
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
KR20220008824A (en) 2019-04-17 2022-01-21 컴퍼스 패쓰파인더 리미티드 How to treat anxiety disorders, headache disorders and eating disorders with psilocybin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2823204A (en) * 1956-03-30 1958-02-11 Gobey Lab Alkaloids of voacanga

Also Published As

Publication number Publication date
BR9909153A (en) 2000-11-14
CA2325879A1 (en) 1999-09-30
OA11491A (en) 2004-05-07
AP2000001926A0 (en) 2000-09-30
AU2742799A (en) 1999-10-18
EP1067938A1 (en) 2001-01-17
WO1999048501A1 (en) 1999-09-30
JP2002507570A (en) 2002-03-12
WO1999048501A9 (en) 2000-03-16
ZA200006020B (en) 2001-06-25

Similar Documents

Publication Publication Date Title
ITTO980264A1 (en) APPLICATION OF A NON-QUATERNARY BASIC EXTRACT OF FUCHSIAEFOLIA PESCHIERA WITH ANTI-MALARICA ACTIVITY
Bliujiene et al. Exotic Lands, Quixotic Friends: Eastern Lithuania and the Carpathian Basin in Late Antiquity and the Early Middle Ages (AD c 380 to c 620
BR0010688A (en) Surface-modified mixed oxides containing noble metal and titanium for selective hydrocarbon oxidation
Roberts et al. Drawing boundaries and building models: investigating the concept of the ‘Chalcolithic frontier’in Northwest Europe
Behr The origins of kingship in early medieval Kent
Bujak Proposed phylogeny of the dinoflagellates Rhombodinium and Gochtodinium
EP1421178A4 (en) Improved methods for producing oocysts
Tencatt et al. A new species of Corydoras Lacépède, 1803 (Siluriformes: Callichthyidae) from the río Madre de Dios basin, Peru
Armit Inside Kurtz's compound: headhunting and the human body in prehistoric Europe
Muhly et al. Evidence for the sources and use of tin during the Bronze Age of the Near East: a reply to JE Dayton
Rutherford Mycenaean religion
MacLeod The first North American occurrence of the Late Cretaceous elasmobranch Ptychodus rugosus Dixon with comments on the functional morphology of the dentition and dermal denticles
Gallo Redescription of Lepidotes piauhyensis Roxo and Löfgren, 1936 (Neopterygii, Semionotiformes, Semionotidae) from the? Late Jurassic–Early Cretaceous of Brazil
Howes Smith A study of 9th-7th century metal bowls from Western Asia
Young Has anyone seen the Barbarians? Remarks on the missing archeology of the Visigoths in Gaul
Abungu Agriculture and settlement formation along the East African coast
Brodacki Functional anatomy and mode of life of the latest Jurassic crinoid Saccocoma
Bałuk et al. Free-living bryozoans from the Korytnica Clays (Middle Miocene; Holy Cross Mountains, Central Poland)
Konstantinidi-Syvridi Mycenae, Shaft Grave III: tomb of the high priestess?
Kunimatsu et al. A newly discovered galagid fossil from Nakali, an early Late Miocene locality of East Africa
Magnus Brooches on the move in Migration Period Europe
Buchholz Odin: Celtic and Siberian affinities of a Germanic deity
Luuk Symbol and its evolution
Muir-Wood Homoeomorphy in recent Brachiopoda: Abyssothyris and Neorhynchia
Hibbard Tanupolama vera (Matthew) from the late Hemphillian of Beaver County, Oklahoma