IN2015DN03012A - - Google Patents

Info

Publication number
IN2015DN03012A
IN2015DN03012A IN3012DEN2015A IN2015DN03012A IN 2015DN03012 A IN2015DN03012 A IN 2015DN03012A IN 3012DEN2015 A IN3012DEN2015 A IN 3012DEN2015A IN 2015DN03012 A IN2015DN03012 A IN 2015DN03012A
Authority
IN
India
Prior art keywords
compound
mixture
hydrogen atom
solution
solvent
Prior art date
Application number
Inventor
Kitsuyama Hirohide
Nagaya Akihiro
Yoshino Hironobu
Hidaka Ikurnasa
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of IN2015DN03012A publication Critical patent/IN2015DN03012A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered

Abstract

[Problem] To provide a method for producing a nitrogen- containing heterocyclic compound with high purity. [Solution] A method for producing a compound (A) of high purity, which comprises the step (a) and the step (b) described below. (a) a step wherein a mixture that contains the compound (A) and a compound (B) which is an impurity , is mixed with a solvent and a metal salt (b) a step wherein a mixture , which contains a smaller amount of the compound (B) in comparison to the mixture in step (a), is obtained in the form of a solution by filtering the mixed solution that is obtained in step (a) , or alternatively a mixture , which contains a smaller amount of the compound (B) in comparison to the mixture in step (a) is obtained by removing the solvent by distillation or carrying out crystallization after the filtration. (In the formulae each of R1 and R2 independently represents a hydrogen atom, a Ci.6. alkyl group or the like; R3 represents a hydrogen atom, a Ci.6 alkyl group or the like; and X represents a hydrogen atom or the like.)
IN3012DEN2015 2012-09-27 2013-09-27 IN2015DN03012A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012215046 2012-09-27
PCT/JP2013/076330 WO2014051077A1 (en) 2012-09-27 2013-09-27 Method for producing nitrogen-containing heterocyclic compound of high purity

Publications (1)

Publication Number Publication Date
IN2015DN03012A true IN2015DN03012A (en) 2015-10-02

Family

ID=50388470

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3012DEN2015 IN2015DN03012A (en) 2012-09-27 2013-09-27

Country Status (5)

Country Link
US (1) US9464095B2 (en)
JP (1) JPWO2014051077A1 (en)
CN (1) CN104507949B (en)
IN (1) IN2015DN03012A (en)
WO (1) WO2014051077A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104507948B (en) * 2012-09-27 2017-05-03 日产化学工业株式会社 Method for producing nitrogenated heterocyclic N-oxide compound
US20220071951A1 (en) 2018-12-28 2022-03-10 Osaka University Therapeutic agent for inherited bradyarrhythmia
EP4173623A1 (en) 2020-06-26 2023-05-03 Osaka University Therapeutic agent for drug-induced bradycardia and bradyarrhythmia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
JP4840594B2 (en) * 2004-03-23 2011-12-21 日産化学工業株式会社 Tricyclic benzopyran compounds as antiarrhythmic drugs
WO2007105658A1 (en) * 2006-03-10 2007-09-20 Nissan Chemical Industries, Ltd. Process for producing optically active chromene oxide compound
CN104507948B (en) * 2012-09-27 2017-05-03 日产化学工业株式会社 Method for producing nitrogenated heterocyclic N-oxide compound

Also Published As

Publication number Publication date
CN104507949A (en) 2015-04-08
US9464095B2 (en) 2016-10-11
CN104507949B (en) 2017-07-28
US20150239899A1 (en) 2015-08-27
JPWO2014051077A1 (en) 2016-08-25
WO2014051077A1 (en) 2014-04-03

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