IN2015DN02381A - - Google Patents

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Publication number
IN2015DN02381A
IN2015DN02381A IN2381DEN2015A IN2015DN02381A IN 2015DN02381 A IN2015DN02381 A IN 2015DN02381A IN 2381DEN2015 A IN2381DEN2015 A IN 2381DEN2015A IN 2015DN02381 A IN2015DN02381 A IN 2015DN02381A
Authority
IN
India
Prior art keywords
lysine
hydroxy
cells
hydroxyl group
present
Prior art date
Application number
Inventor
Kuniki Kino
Ryotaro Hara
Ryoma Miyake
Hiroshi Kawabata
Original Assignee
Api Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Api Corp filed Critical Api Corp
Publication of IN2015DN02381A publication Critical patent/IN2015DN02381A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
    • C12Y114/11004—Procollagen-lysine 5-dioxygenase (1.14.11.4), i.e. lysine-hydroxylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention addresses the issue of providing a method whereby hydroxy -L- lysine can be efficiently produced. The present invention provides a production method for hydroxy- L- lysine, characterized by: causing a 2- oxoglutarate dependent L- lysine hydroxylase , cells including same, a preparation of said cells , or a culture fluid obtained by cultivating said cells, to act on L -lysine; and generating the hydroxy- L -lysine indicated in general formula (I) (in the formula , R1, R2, and R3 each indicate a hydrogen atom or a hydroxyl group and at least one among R1, R2 , and R3 indicates a hydroxyl group.)
IN2381DEN2015 2013-02-19 2014-02-18 IN2015DN02381A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013030311 2013-02-19
PCT/JP2014/053774 WO2014129459A1 (en) 2013-02-19 2014-02-18 Production method for l-lysine hydroxylase and hydroxy-l-lysine using same, and production method for hydroxy-l-pipecolic acid

Publications (1)

Publication Number Publication Date
IN2015DN02381A true IN2015DN02381A (en) 2015-09-04

Family

ID=51391249

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2381DEN2015 IN2015DN02381A (en) 2013-02-19 2014-02-18

Country Status (6)

Country Link
US (1) US9512452B2 (en)
EP (1) EP2889378B1 (en)
JP (2) JP6476110B2 (en)
CN (1) CN104685061B (en)
IN (1) IN2015DN02381A (en)
WO (1) WO2014129459A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6476110B2 (en) * 2013-02-19 2019-02-27 株式会社エーピーアイ コーポレーション L-lysine hydroxylase, method for producing hydroxy-L-lysine using the same, and method for producing hydroxy-L-pipecolic acid
EP2876156A1 (en) * 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof
EP3358016A4 (en) * 2015-10-02 2018-11-14 API Corporation Method for producing hydroxy-l-pipecolic acid
CN107287255A (en) * 2016-03-31 2017-10-24 南京诺云生物科技有限公司 The new application of Pseudomonas veronii CIP104663 albumen
CN107630049B (en) * 2017-04-01 2018-09-21 武汉茵茂特生物技术有限公司 The biological preparation method of ephedrine
CN112930338A (en) 2018-09-21 2021-06-08 株式会社Api Process for the preparation of amino acid derivatives
CN113710812A (en) 2019-04-19 2021-11-26 株式会社Api Process for producing (1R,3R) -3- (trifluoromethyl) cyclohexan-1-ol and intermediate thereof
JP7386616B2 (en) * 2019-04-25 2023-11-27 株式会社エーピーアイ コーポレーション Method for producing L-cyclic amino acid

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57183799A (en) 1981-04-17 1982-11-12 Kyowa Hakko Kogyo Co Ltd Novel plasmid
ES2317857T3 (en) 1999-12-28 2009-05-01 Mercian Corporation PROCESS FOR THE BIOLOGICAL PRODUCTION OF L-PIPECOLIC ACID.
FR2812635B1 (en) 2000-08-01 2002-10-11 Aventis Pharma Sa NOVEL HETEROCYCLIC COMPOUNDS, PREPARATION AND USE AS MEDICAMENTS IN PARTICULAR AS ANTI-BACTERIALS
FR2825717B1 (en) 2001-06-08 2005-02-18 Rhodia Chimie Sa STEREOSELECTIVE PREPARATION OF CYCLIC AMINO ACIDS
JP4590981B2 (en) * 2003-08-26 2010-12-01 三菱化学株式会社 Method for producing optically active cyclic amino acid
JP5395395B2 (en) 2008-10-10 2014-01-22 北興化学工業株式会社 Production of cyclic amino acids by microorganisms
SG187652A1 (en) 2010-08-31 2013-03-28 Api Corp Novel hydrolase protein
WO2014098188A1 (en) 2012-12-20 2014-06-26 株式会社エーピーアイ コーポレーション METHOD FOR PRODUCING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID DERIVATIVE, AND METHOD FOR PURIFYING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID
JP6476110B2 (en) * 2013-02-19 2019-02-27 株式会社エーピーアイ コーポレーション L-lysine hydroxylase, method for producing hydroxy-L-lysine using the same, and method for producing hydroxy-L-pipecolic acid
EP2876156A1 (en) 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof
WO2015098774A1 (en) 2013-12-26 2015-07-02 株式会社カネカ Production method for optically active cyclic imino acid

Also Published As

Publication number Publication date
JP6476110B2 (en) 2019-02-27
WO2014129459A1 (en) 2014-08-28
US20150259715A1 (en) 2015-09-17
CN104685061A (en) 2015-06-03
JP2019062927A (en) 2019-04-25
CN104685061B (en) 2018-05-01
JPWO2014129459A1 (en) 2017-02-02
EP2889378A4 (en) 2016-03-09
EP2889378A1 (en) 2015-07-01
US9512452B2 (en) 2016-12-06
EP2889378B1 (en) 2018-01-10

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