IN2013CN00459A - - Google Patents

Download PDF

Info

Publication number
IN2013CN00459A
IN2013CN00459A IN459CHN2013A IN2013CN00459A IN 2013CN00459 A IN2013CN00459 A IN 2013CN00459A IN 459CHN2013 A IN459CHN2013 A IN 459CHN2013A IN 2013CN00459 A IN2013CN00459 A IN 2013CN00459A
Authority
IN
India
Prior art keywords
dicarboxylic acid
methods
relates
present
dicarboxylic
Prior art date
Application number
Inventor
Sheryl Luttringer
Debbie Yaver
Original Assignee
Novozymes Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Inc filed Critical Novozymes Inc
Publication of IN2013CN00459A publication Critical patent/IN2013CN00459A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to methods of producing C4 dicarboxylic acids such as malic acid comprising: (a) cultivating a host cell comprising a polynucleotide encoding a C4 dicarboxylic acid transporter; and (b) recovering the C4 dicarboxylic acid. The present invention also relates to methods for increasing C4 dicarboxylic acid production as well as host cells comprising the polynucleotides.
IN459CHN2013 2010-06-21 2011-06-21 IN2013CN00459A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35700710P 2010-06-21 2010-06-21
PCT/US2011/041301 WO2011163270A1 (en) 2010-06-21 2011-06-21 Methods for improved c4-dicarboxylic acid production in filamentous fungi

Publications (1)

Publication Number Publication Date
IN2013CN00459A true IN2013CN00459A (en) 2015-07-03

Family

ID=44504321

Family Applications (1)

Application Number Title Priority Date Filing Date
IN459CHN2013 IN2013CN00459A (en) 2010-06-21 2011-06-21

Country Status (6)

Country Link
US (2) US8497103B2 (en)
EP (1) EP2582829B1 (en)
CN (1) CN102947458B (en)
BR (1) BR112012028031A2 (en)
IN (1) IN2013CN00459A (en)
WO (1) WO2011163270A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2012002532A (en) * 2009-09-01 2012-04-11 Novozymes Inc Methods for improving malic acid production in filamentous fungi.
WO2014142647A1 (en) * 2013-03-14 2014-09-18 Wageningen Universiteit Fungals strains with improved citric acid and itaconic acid production
EP3161142A4 (en) * 2014-06-26 2018-05-16 Lygos, Inc. Recombinant host cells for the production of malonate
CN106148209B (en) * 2015-03-23 2020-11-20 中国科学院天津工业生物技术研究所 Novel binary organic acid producing strain and preparation and application thereof
BR112017017262A2 (en) * 2015-02-15 2018-04-17 Tianjin Inst Ind Biotechnology Cas strain of dibasic organic acid production, preparation and application thereof
CN106148208B (en) * 2015-03-23 2020-12-18 中国科学院天津工业生物技术研究所 Novel binary organic acid producing strain and preparation and application thereof
JP6637712B2 (en) * 2015-10-13 2020-01-29 花王株式会社 Method for producing C4 dicarboxylic acid
CN105754963A (en) * 2016-05-19 2016-07-13 江南大学 Method for improving yield of fumaric acid
US20190194700A1 (en) * 2016-09-15 2019-06-27 Kao Corporation Mutant Filamentous Fungus and Method for Producing C4 Dicarboxylic Acid Using Same
CN114806899B (en) * 2022-04-14 2024-04-02 王玮 Trichoderma reesei engineering bacteria for producing L-malic acid and application thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1047002A (en) 1911-04-03 1912-12-10 James S Diehl Scissors.
US3063910A (en) 1960-02-03 1962-11-13 Kyowa Hakko Kogyo Kk Method of producing l-malic acid by fermentation
DK122686D0 (en) 1986-03-17 1986-03-17 Novo Industri As PREPARATION OF PROTEINS
US5536661A (en) 1987-03-10 1996-07-16 Novo Nordisk A/S Process for the production of protein products in aspergillus
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE4343591A1 (en) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Process for the evolutionary design and synthesis of functional polymers based on shape elements and shape codes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
JP3649338B2 (en) 1994-06-03 2005-05-18 ノボザイムス バイオテック，インコーポレイティド Purified Myserioftra laccase and nucleic acid encoding it
EP1559776A3 (en) 1994-06-30 2006-01-11 Novozymes Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic Fusarium expression system and promoters and terminators for use therein
US5766439A (en) 1996-10-10 1998-06-16 A. E. Staley Manufacturing Co. Production and recovery of organic acids
US7504490B1 (en) * 1998-10-16 2009-03-17 Oscient Pharmaceuticals Corporation Nucleic acid and amino acid sequences relating to Apergillus fumigatus for diagnostics and therapeutics
DK1124949T3 (en) 1998-10-26 2006-11-06 Novozymes As Construction and screening of a DNA library of interest in filamentous fungal cells
CN100482801C (en) 1999-03-22 2009-04-29 诺沃奇梅兹有限公司 Promoters for expressing genes in fungal cell
US7601865B2 (en) 2004-01-29 2009-10-13 Zeachem, Inc. Recovery of organic acids
US20080090273A1 (en) * 2005-11-21 2008-04-17 Aaron Adriaan Winkler Malic Acid Production in Recombinant Yeast
EP2155885A4 (en) 2007-05-18 2010-12-01 Microbia Prec Engineering Inc Malic acid production in recombinant yeast
EP2158323A4 (en) 2007-05-18 2011-06-22 Microbia Prec Engineering Inc Organic acid production by fungal cells
BRPI0819273B8 (en) 2007-11-20 2022-07-19 Dsm Ip Assets Bv RECOMBINANT EUKARYOTIC MICROBIAL CELL AND PROCESS FOR THE PREPARATION OF A DICARBOXYLIC ACID
EP2304039B1 (en) 2008-06-17 2019-08-21 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
US9012187B2 (en) 2008-07-08 2015-04-21 Dsm Ip Assets B.V. Dicarboxylic acid production by fermentation at low pH
WO2010111344A2 (en) 2009-03-24 2010-09-30 Microbia, Inc. Methods and microorganisms for production of c4-dicarboxylic acids
JP2012223091A (en) 2009-08-25 2012-11-15 Ajinomoto Co Inc Method for producing l-amino acid
MX2012002532A (en) 2009-09-01 2012-04-11 Novozymes Inc Methods for improving malic acid production in filamentous fungi.
WO2011066304A2 (en) 2009-11-25 2011-06-03 Codexis, Inc. Engineered beta-class carbonic anhydrase polypeptides and uses thereof

Also Published As

Publication number Publication date
US20130288321A1 (en) 2013-10-31
EP2582829B1 (en) 2016-11-30
WO2011163270A1 (en) 2011-12-29
CN102947458B (en) 2016-05-04
BR112012028031A2 (en) 2019-09-24
US20110312046A1 (en) 2011-12-22
US8497103B2 (en) 2013-07-30
CN102947458A (en) 2013-02-27
EP2582829A1 (en) 2013-04-24

Similar Documents

Publication Publication Date Title
IN2013CN00459A (en)
IN2014CN04586A (en)
MX2012002532A (en) Methods for improving malic acid production in filamentous fungi.
WO2012103300A8 (en) Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
MX337919B (en) Polypeptides having cellobiohydrolase activity and polynucleotides encoding same.
SG171538A1 (en) Candida tropicalis cells and use thereof
MX2012006096A (en) Polypeptides having glucoamylase activity and polynucleotides encoding same.
MY187101A (en) Production of long chain polyunsaturated fatty acids in plant cells
MX2019004568A (en) Improved production of fatty acid derivatives.
MX353621B (en) Alpha-amylase variants.
MX337913B (en) Polypeptides having cellobiohydrolase activity and polynucleotides encoding same.
MY155569A (en) Recombinant cells producing ? - aminocarboxylic acid ? - aminocarboxylic acid esters or their lactams
EP4026901A3 (en) Method for screening alpha-amylases
EP3091073A3 (en) Polypeptides having xylanase activity and polynucleotides encoding same
ZA201305411B (en) Method for producing formic acid by reacting carbon dioxide with hydrogen
MX2013004353A (en) Recombinant n-propanol and isopropanol production.
MY180098A (en) Novel process for preparing silicas
MX2011009025A (en) Expression vector system comprising two selection markers.
IN2012DN00469A (en)
MX2014001594A (en) Polypeptides having cellulase activity and polynucleotides encoding same.
MX349517B (en) Polypeptides having protease activity and polynucleotides encoding same.
MY163070A (en) Process to produce valerolactone from levulinic acid
MX2012007868A (en) Method for preparing tetrazole methanesulfonic acid salts, and novel compound used in same.
MX364390B (en) Use of polypeptides having protease activity in animal feed and detergents.
CA2894261C (en) Alpha-amylases and polynucleotides encoding same