IL150020A0 - High throughput or capillary-based screening for a bioactivity or biomolecule - Google Patents

High throughput or capillary-based screening for a bioactivity or biomolecule

Info

Publication number
IL150020A0
IL150020A0 IL15002001A IL15002001A IL150020A0 IL 150020 A0 IL150020 A0 IL 150020A0 IL 15002001 A IL15002001 A IL 15002001A IL 15002001 A IL15002001 A IL 15002001A IL 150020 A0 IL150020 A0 IL 150020A0
Authority
IL
Israel
Prior art keywords
biomolecule
bioactivity
capillary
high throughput
based screening
Prior art date
Application number
IL15002001A
Original Assignee
Diversa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/738,871 external-priority patent/US20010041333A1/en
Priority claimed from US09/790,321 external-priority patent/US20020048809A1/en
Priority claimed from US09/894,956 external-priority patent/US20020015997A1/en
Application filed by Diversa Corp filed Critical Diversa Corp
Publication of IL150020A0 publication Critical patent/IL150020A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
IL15002001A 2000-10-10 2001-10-10 High throughput or capillary-based screening for a bioactivity or biomolecule IL150020A0 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US68543200A 2000-10-10 2000-10-10
US09/738,871 US20010041333A1 (en) 1997-06-16 2000-12-15 High throughput screening for a bioactivity or biomolecule
US09/790,321 US20020048809A1 (en) 1997-06-16 2001-02-21 Capillary array-based sample screening
US09/894,956 US20020015997A1 (en) 1997-06-16 2001-06-27 Capillary array-based sample screening
US30910101P 2001-07-31 2001-07-31
PCT/US2001/031806 WO2002031203A2 (en) 2000-10-10 2001-10-10 High throughput or capillary-based screening for a bioactivity or biomolecule

Publications (1)

Publication Number Publication Date
IL150020A0 true IL150020A0 (en) 2002-12-01

Family

ID=27540945

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15002001A IL150020A0 (en) 2000-10-10 2001-10-10 High throughput or capillary-based screening for a bioactivity or biomolecule

Country Status (7)

Country Link
EP (1) EP1364052A2 (en)
JP (1) JP2005501217A (en)
AU (1) AU1164202A (en)
CA (1) CA2393374A1 (en)
IL (1) IL150020A0 (en)
MX (1) MXPA02005717A (en)
WO (1) WO2002031203A2 (en)

Families Citing this family (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
US7960148B2 (en) 2003-07-02 2011-06-14 Verenium Corporation Glucanases, nucleic acids encoding them and methods for making and using them
CA2891101A1 (en) 2003-08-11 2005-03-10 Basf Enzymes Llc Laccases, nucleic acids encoding them and methods for making and using them
CA2542219A1 (en) * 2003-10-10 2005-04-21 Biophysical Corporation Generation of biochemical images and methods of use
US20050221339A1 (en) * 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
EP2468853B1 (en) 2004-06-16 2015-04-01 DSM IP Assets B.V. Method for enzymatic decolorization of pheophytin
US20080070291A1 (en) 2004-06-16 2008-03-20 David Lam Compositions and Methods for Enzymatic Decolorization of Chlorophyll
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
EP2886658A1 (en) 2005-03-10 2015-06-24 BASF Enzymes LLC Lyase enzymes, nucleic acids encoding them and methods for making and using them
CA2861310A1 (en) 2005-03-15 2006-09-28 Bp Corporation North America Inc. Cellulases, nucleic acids encoding them and methods for making and using them
JP2009536313A (en) 2006-01-11 2009-10-08 レインダンス テクノロジーズ, インコーポレイテッド Microfluidic devices and methods for use in nanoreactor formation and control
NZ571087A (en) 2006-02-10 2012-04-27 Verenium Corp Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them
USRE45660E1 (en) 2006-02-14 2015-09-01 Bp Corporation North America Inc. Xylanases, nucleic acids encoding them and methods for making and using them
BR122017003017B1 (en) 2006-03-07 2018-10-23 Basf Enzymes Llc NUCLEIC ACID, EXPRESSION CASSETTE, VECTOR, CLONING VEHICLE, MOTRANSGENIC MICROORGANISM, POLYPEPTIDE, SIGNAL PEPTIDE, COMPOSITION, AND METHODS TO PRODUCE A RECOMBINANT CARIAN CARD A NON-CARBONIZED LIP FOR A NERCARIOUS CARBON TO FORM A CARBON-CARBON CONNECTION, TO MAKE A FOOD, FEED OR DRINK, AND TO CONVERT A BIOMASS ANY LIGNOCELLULOSTIC MATERIAL INTO A FUEL
CN101437954B (en) 2006-03-07 2015-09-09 嘉吉公司 The nucleic acid of zymohexase and coding zymohexase and their preparation and application
EP2530168B1 (en) 2006-05-11 2015-09-16 Raindance Technologies, Inc. Microfluidic Devices
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
DK2069389T3 (en) 2006-08-04 2015-01-12 Bp Corp North America Inc Glucanases, nucleic acids encoding them, and processes for their preparation and use
WO2008021123A1 (en) 2006-08-07 2008-02-21 President And Fellows Of Harvard College Fluorocarbon emulsion stabilizing surfactants
WO2008095033A2 (en) 2007-01-30 2008-08-07 Verenium Corporation Enzymes for the treatment of lignocellulosics, nucleic acids encoding them and methods for making and using them
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
WO2008109176A2 (en) * 2007-03-07 2008-09-12 President And Fellows Of Harvard College Assays and other reactions involving droplets
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
BRPI0817811A2 (en) 2007-10-03 2014-10-14 Verenium Corp Xylanases, nucleic acids that encode the same and methods for the manufacture and use of the same.
EP2235210B1 (en) 2007-12-21 2015-03-25 President and Fellows of Harvard College Methods for nucleic acid sequencing
PL2238242T3 (en) 2008-01-03 2015-06-30 Basf Enzymes Llc Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them
WO2010009365A1 (en) 2008-07-18 2010-01-21 Raindance Technologies, Inc. Droplet libraries
US20110218123A1 (en) 2008-09-19 2011-09-08 President And Fellows Of Harvard College Creation of libraries of droplets and related species
EP3290531B1 (en) 2008-12-19 2019-07-24 President and Fellows of Harvard College Particle-assisted nucleic acid sequencing
EP3415235A1 (en) 2009-03-23 2018-12-19 Raindance Technologies Inc. Manipulation of microfluidic droplets
WO2011042564A1 (en) 2009-10-09 2011-04-14 Universite De Strasbourg Labelled silica-based nanomaterial with enhanced properties and uses thereof
US9056289B2 (en) 2009-10-27 2015-06-16 President And Fellows Of Harvard College Droplet creation techniques
US10837883B2 (en) 2009-12-23 2020-11-17 Bio-Rad Laboratories, Inc. Microfluidic systems and methods for reducing the exchange of molecules between droplets
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
JP5934657B2 (en) 2010-02-12 2016-06-15 レインダンス テクノロジーズ, インコーポレイテッド Digital specimen analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US20130203606A1 (en) * 2010-02-25 2013-08-08 Advanced Liquid Logic Inc Method of Preparing a Nucleic Acid Library
KR101255828B1 (en) * 2010-05-25 2013-04-24 주식회사 나노엔텍 Qualitative and quantitative analytical method for analyzing the activity type of an enzyme that is activated by proteolysis
EP3447155A1 (en) 2010-09-30 2019-02-27 Raindance Technologies, Inc. Sandwich assays in droplets
WO2012109600A2 (en) 2011-02-11 2012-08-16 Raindance Technologies, Inc. Methods for forming mixed droplets
EP2675819B1 (en) 2011-02-18 2020-04-08 Bio-Rad Laboratories, Inc. Compositions and methods for molecular labeling
US20140154184A1 (en) * 2011-04-28 2014-06-05 The Regents Of The University Of California Time-gated fluorescence imaging with si-containing particles
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
EP2714970B1 (en) 2011-06-02 2017-04-19 Raindance Technologies, Inc. Enzyme quantification
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
ES2678211T3 (en) 2012-03-27 2018-08-09 Ventana Medical Systems, Inc. Signaling conjugates and use procedures
US9657290B2 (en) 2012-07-03 2017-05-23 The Board Of Trustees Of The Leland Stanford Junior University Scalable bio-element analysis
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9567631B2 (en) 2012-12-14 2017-02-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
US10221442B2 (en) 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
KR102090851B1 (en) 2012-08-14 2020-03-19 10엑스 제노믹스, 인크. Microcapsule compositions and methods
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10400280B2 (en) 2012-08-14 2019-09-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
CN108753766A (en) 2013-02-08 2018-11-06 10X基因组学有限公司 Polynucleotides bar code generating at
US10395758B2 (en) 2013-08-30 2019-08-27 10X Genomics, Inc. Sequencing methods
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
WO2015069634A1 (en) 2013-11-08 2015-05-14 President And Fellows Of Harvard College Microparticles, methods for their preparation and use
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
US9824068B2 (en) 2013-12-16 2017-11-21 10X Genomics, Inc. Methods and apparatus for sorting data
WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
CN106413896B (en) 2014-04-10 2019-07-05 10X基因组学有限公司 For encapsulating and dividing fluid means, system and method and its application of reagent
EP3889325A1 (en) 2014-06-26 2021-10-06 10X Genomics, Inc. Methods of analyzing nucleic acids from individual cells or cell populations
US10839939B2 (en) 2014-06-26 2020-11-17 10X Genomics, Inc. Processes and systems for nucleic acid sequence assembly
MX2017005267A (en) 2014-10-29 2017-07-26 10X Genomics Inc Methods and compositions for targeted nucleic acid sequencing.
US9975122B2 (en) 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
AU2016207023B2 (en) 2015-01-12 2019-12-05 10X Genomics, Inc. Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
KR20170106979A (en) 2015-01-13 2017-09-22 10엑스 제노믹스, 인크. System and method for visualizing structure variation and phase adjustment information
JP2018513445A (en) 2015-02-09 2018-05-24 10エックス ゲノミクス,インコーポレイテッド System and method for fading using structural variation identification and variant call data
CN107532333A (en) 2015-02-22 2018-01-02 里兰斯坦福初级大学理事会 Microtraps screening device, method and product
WO2016137973A1 (en) 2015-02-24 2016-09-01 10X Genomics Inc Partition processing methods and systems
EP3262188B1 (en) 2015-02-24 2021-05-05 10X Genomics, Inc. Methods for targeted nucleic acid sequence coverage
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
US11123297B2 (en) 2015-10-13 2021-09-21 President And Fellows Of Harvard College Systems and methods for making and using gel microspheres
JP6954899B2 (en) 2015-12-04 2021-10-27 10エックス ゲノミクス,インコーポレイテッド Methods and compositions for nucleic acid analysis
JP6735348B2 (en) 2016-02-11 2020-08-05 10エックス ジェノミクス, インコーポレイテッド Systems, methods and media for de novo assembly of whole genome sequence data
WO2017197338A1 (en) 2016-05-13 2017-11-16 10X Genomics, Inc. Microfluidic systems and methods of use
CN115254210A (en) 2016-11-14 2022-11-01 浩康生物系统公司 Method and apparatus for sorting target particles
US11085039B2 (en) 2016-12-12 2021-08-10 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
WO2018111765A1 (en) 2016-12-12 2018-06-21 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
JP7208902B2 (en) 2016-12-30 2023-01-19 エクセラ・バイオサイエンシーズ・インコーポレイテッド Multi-stage sample collection system
WO2018140966A1 (en) 2017-01-30 2018-08-02 10X Genomics, Inc. Methods and systems for droplet-based single cell barcoding
CN110870018A (en) 2017-05-19 2020-03-06 10X基因组学有限公司 System and method for analyzing a data set
CN109526228B (en) 2017-05-26 2022-11-25 10X基因组学有限公司 Single cell analysis of transposase accessible chromatin
US20180340169A1 (en) 2017-05-26 2018-11-29 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
SG11201913654QA (en) 2017-11-15 2020-01-30 10X Genomics Inc Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
EP3775271A1 (en) 2018-04-06 2021-02-17 10X Genomics, Inc. Systems and methods for quality control in single cell processing
CN109682786B (en) * 2019-01-16 2021-11-12 四川省畜牧科学研究院 Method for identifying haemonchus contortus eggs and application thereof
CN110047572A (en) * 2019-03-14 2019-07-23 周军河 A kind of intelligence warm spring system and application method
CN116675285B (en) * 2023-05-15 2023-11-10 苏州科技大学 Degradation method of perfluoro compound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853984A (en) * 1990-06-11 1998-12-29 Nexstar Pharmaceuticals, Inc. Use of nucleic acid ligands in flow cytometry
DE69322266T2 (en) * 1992-04-03 1999-06-02 Perkin Elmer Corp SAMPLES COMPOSITION AND METHOD
US5958672A (en) * 1995-07-18 1999-09-28 Diversa Corporation Protein activity screening of clones having DNA from uncultivated microorganisms
US6057103A (en) * 1995-07-18 2000-05-02 Diversa Corporation Screening for novel bioactivities
US20030215798A1 (en) * 1997-06-16 2003-11-20 Diversa Corporation High throughput fluorescence-based screening for novel enzymes
JP2000506007A (en) * 1996-02-23 2000-05-23 アリアド・ファーマシューティカルズ・インコーポレイテッド Cell-based assays
JP2002531056A (en) * 1998-08-07 2002-09-24 セレイ, エルエルシー Gel microdrop in gene analysis

Also Published As

Publication number Publication date
EP1364052A2 (en) 2003-11-26
MXPA02005717A (en) 2003-10-14
JP2005501217A (en) 2005-01-13
WO2002031203A2 (en) 2002-04-18
WO2002031203A3 (en) 2003-09-25
CA2393374A1 (en) 2002-04-18
WO2002031203A9 (en) 2003-07-03
AU1164202A (en) 2002-04-22

Similar Documents

Publication Publication Date Title
IL150020A0 (en) High throughput or capillary-based screening for a bioactivity or biomolecule
HUP0102915A3 (en) High throughput screen
EP1229125A4 (en) Process for producing polypeptide
EP1378749A4 (en) Screening method
AUPP904499A0 (en) A screening apparatus
GB0018140D0 (en) Screening for abnormalities
GB9922352D0 (en) Screening method
IL147637A0 (en) Sequence based screening
GB9923075D0 (en) Screening method
EP1237001A4 (en) Screening method
GB2350070B (en) Screening apparatus
GB0028578D0 (en) Screening assays
GB0021682D0 (en) Screening method 2
GB9930255D0 (en) Screening method
GB9924929D0 (en) Screening apparatus
GB0100754D0 (en) Screening device
GB2377907B (en) Method suitable for forming shaped screens
AU7740301A (en) Screening apparatus
AU2000224577A1 (en) Screening method
GB0029373D0 (en) Screening method
GB9928430D0 (en) Screening
TW485847U (en) Screening machine for heavy matter
GB0004629D0 (en) Screening method
GB0031273D0 (en) Screening method
GB0030504D0 (en) Screening method