IL115849A0 - Tangential filtration preparation of liposomal drugs and liposome product thereof - Google Patents

Tangential filtration preparation of liposomal drugs and liposome product thereof

Info

Publication number
IL115849A0
IL115849A0 IL11584995A IL11584995A IL115849A0 IL 115849 A0 IL115849 A0 IL 115849A0 IL 11584995 A IL11584995 A IL 11584995A IL 11584995 A IL11584995 A IL 11584995A IL 115849 A0 IL115849 A0 IL 115849A0
Authority
IL
Israel
Prior art keywords
tangential filtration
liposome product
liposomal drugs
filtration preparation
preparation
Prior art date
Application number
IL11584995A
Original Assignee
Merz & Co Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz & Co Gmbh & Co filed Critical Merz & Co Gmbh & Co
Publication of IL115849A0 publication Critical patent/IL115849A0/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
IL11584995A 1994-11-03 1995-11-02 Tangential filtration preparation of liposomal drugs and liposome product thereof IL115849A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33379094A 1994-11-03 1994-11-03

Publications (1)

Publication Number Publication Date
IL115849A0 true IL115849A0 (en) 1996-01-31

Family

ID=23304261

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11584995A IL115849A0 (en) 1994-11-03 1995-11-02 Tangential filtration preparation of liposomal drugs and liposome product thereof

Country Status (2)

Country Link
IL (1) IL115849A0 (en)
WO (1) WO1996014057A1 (en)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827533A (en) 1997-02-06 1998-10-27 Duke University Liposomes containing active agents aggregated with lipid surfactants
JP4467789B2 (en) 1997-09-18 2010-05-26 パシラ ファーマシューティカルズ インコーポレーテッド Sustained release liposome anesthetic composition
IL135989A0 (en) 1997-11-14 2001-05-20 Skyepharma Inc Processes for the production of multivesicular liposomes
EP3604537B1 (en) 2003-06-13 2021-12-08 Alnylam Europe AG Double-stranded ribonucleic acid with increased effectiveness in an organism
WO2005060968A1 (en) 2003-12-11 2005-07-07 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
MXPA06009634A (en) 2004-02-24 2007-04-23 Gen Hospital Corp Catalytic radiofluorination.
US7674778B2 (en) 2004-04-30 2010-03-09 Alnylam Pharmaceuticals Oligonucleotides comprising a conjugate group linked through a C5-modified pyrimidine
CN101006065B (en) 2004-06-17 2012-07-11 英菲尼蒂发现公司 Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
US8669236B2 (en) 2005-05-12 2014-03-11 The General Hospital Corporation Biotinylated compositions
AU2007281212B8 (en) 2006-08-03 2013-02-28 Trustees Of Tufts College Non-flushing niacin analogues, and methods of use thereof
EP2065058A1 (en) 2007-11-28 2009-06-03 Koninklijke Philips Electronics N.V. Non-spherical contrast agents for CEST MRI based on bulk magnetic susceptibility effect
EP2067485A1 (en) 2007-12-07 2009-06-10 Koninklijke Philips Electronics N.V. Drug carrier providing MRI contrast enhancement
US9492417B2 (en) 2008-08-21 2016-11-15 The Johns Hopkins University Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer
BR122020021379B1 (en) 2008-10-24 2021-05-11 Sarepta Therapeutics, Inc. morpholino phosphorodiamidate oligomer, composition comprising the same and use of said oligomer to treat muscular dystrophy
AU2010221419B2 (en) 2009-03-02 2015-10-01 Alnylam Pharmaceuticals, Inc. Nucleic acid chemical modifications
EP2305216A1 (en) 2009-09-25 2011-04-06 Koninklijke Philips Electronics N.V. Two step ultrasound protocol for drug delivery
EP3199634A1 (en) 2009-11-13 2017-08-02 Sarepta Therapeutics, Inc. Antisense antiviral compound and method for treating influenza viral infection
EP2545173A2 (en) 2010-03-12 2013-01-16 Sarepta Therapeutics, Inc. Antisense modulation of nuclear hormone receptors
WO2011123621A2 (en) 2010-04-01 2011-10-06 Alnylam Pharmaceuticals Inc. 2' and 5' modified monomers and oligonucleotides
US10913767B2 (en) 2010-04-22 2021-02-09 Alnylam Pharmaceuticals, Inc. Oligonucleotides comprising acyclic and abasic nucleosides and analogs
WO2011133871A2 (en) 2010-04-22 2011-10-27 Alnylam Pharmaceuticals, Inc. 5'-end derivatives
WO2011133868A2 (en) 2010-04-22 2011-10-27 Alnylam Pharmaceuticals, Inc. Conformationally restricted dinucleotide monomers and oligonucleotides
EP2569431B1 (en) 2010-05-13 2015-09-23 Sarepta Therapeutics, Inc. Methods for identifying compounds which modulate interleukins 17 and 23 signaling activity
JP5925770B2 (en) 2010-06-24 2016-05-25 トラスティーズ オブ タフツ カレッジ Niacin mimics and methods of use
CA2802952A1 (en) 2010-06-24 2011-12-29 Arisaph Pharmaceuticals, Inc. Niacin mimetics, and methods of use thereof
EP2407157A1 (en) 2010-07-13 2012-01-18 Koninklijke Philips Electronics N.V. Lipid bilayer carrier for drugs or imaging agents
CN103338747A (en) 2011-01-28 2013-10-02 皇家飞利浦电子股份有限公司 Carriers for the local release of hydrophilic prodrugs
EP2535326A1 (en) 2011-06-16 2012-12-19 Koninklijke Philips Electronics N.V. Novel lipidomimetic compounds and uses thereof
US9907812B2 (en) 2011-06-22 2018-03-06 Vyome Biosciences Pvt. Ltd. Conjugate-based antifungal and antibacterial prodrugs
AU2012284259A1 (en) 2011-07-15 2014-03-06 Sarepta Therapeutics, Inc. Methods and compositions for manipulating translation of protein isoforms from alternative initiation start sites
JP6132848B2 (en) 2011-12-08 2017-05-31 サレプタ セラピューティクス, インコーポレイテッド Oligonucleotide analogues targeting human LMNA
AU2012355624A1 (en) 2011-12-23 2014-07-17 Novartis Ag Compounds for inhibiting the interaction of BCL2 with binding partners
CN104125954A (en) 2011-12-23 2014-10-29 诺华股份有限公司 Compounds for inhibiting interaction of bcl2 with binding partners
CA2859862A1 (en) 2011-12-23 2013-06-27 Novartis Ag Compounds for inhibiting the interaction of bcl2 with binding partners
CN104136429A (en) 2011-12-23 2014-11-05 诺华股份有限公司 Compounds for inhibiting the interaction of bcl2 with binding partners
MX2014007725A (en) 2011-12-23 2015-01-12 Novartis Ag Compounds for inhibiting the interaction of bcl2 with binding partners.
DK2861579T5 (en) 2012-05-15 2022-10-24 Novartis Ag Benzamide derivatives to inhibit the activity of ABL1, ABL2 and BCR-ABL1
CA2870339C (en) 2012-05-15 2020-06-02 Novartis Ag Compounds and compositions for inhibiting the activity of abl1, abl2 and bcr-abl1
AU2013261128B2 (en) 2012-05-15 2015-11-12 Novartis Ag Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1
BR112014027244A2 (en) 2012-05-15 2017-06-27 Novartis Ag benzamide derivatives for inhibition of abl1, abl2 and bcr-abl1 activity
AU2013274101B2 (en) 2012-06-15 2017-09-07 The Brigham And Women's Hospital, Inc. Compositions for treating cancer and methods for making the same
AU2013308519A1 (en) 2012-08-31 2015-04-09 The General Hospital Corporation Biotin complexes for treatment and diagnosis of Alzheimer's disease
CN111440796A (en) 2012-12-20 2020-07-24 萨雷普塔医疗公司 Improved exon skipping compositions for the treatment of muscular dystrophy
JP6364028B2 (en) 2013-02-19 2018-07-25 ノバルティス アーゲー Benzothiophene derivatives and selective compositions as selective estrogen receptor degraders
TR201903009T4 (en) 2013-03-14 2019-03-21 Sarepta Therapeutics Inc Exon skipping compositions for the treatment of muscular dystrophy.
BR112015023001B8 (en) 2013-03-14 2022-08-09 Sarepta Therapeutics Inc ANTISENSE OLIGONUCLEOTIDE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND USE OF SUCH COMPOSITION FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY (DMD)
WO2014144978A2 (en) 2013-03-15 2014-09-18 Sarepta Therapeutics, Inc. Improved compositions for treating muscular dystrophy
MX2015017123A (en) 2013-06-14 2016-08-03 Invictus Oncology Pvt Ltd Lipid-based platinum compounds and nanoparticles.
WO2015022663A1 (en) 2013-08-14 2015-02-19 Novartis Ag Compounds and compositions as inhibitors of mek
WO2015022664A1 (en) 2013-08-14 2015-02-19 Novartis Ag Compounds and compositions as inhibitors of mek
US9227969B2 (en) 2013-08-14 2016-01-05 Novartis Ag Compounds and compositions as inhibitors of MEK
WO2015092634A1 (en) 2013-12-16 2015-06-25 Novartis Ag 1,2,3,4-tetrahydroisoquinoline compounds and compositions as selective estrogen receptor antagonists and degraders
JO3517B1 (en) 2014-01-17 2020-07-05 Novartis Ag N-azaspirocycloalkane substituted n-heteroaryl compounds and compositions for inhibiting the activity of shp2
US9815813B2 (en) 2014-01-17 2017-11-14 Novartis Ag 1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and compositions therefor for inhibiting the activity of SHP2
ES2699351T3 (en) 2014-01-17 2019-02-08 Novartis Ag Derivatives of 1-pyridazin / triazin-3-yl-piper (-azine) / idine / pyrolidine and compositions thereof to inhibit the activity of SHP2
EP3099301B1 (en) 2014-01-29 2019-12-18 Vyome Therapeutics Limited Besifloxacin for the treatment of resistant acne
LT3118311T (en) 2014-03-12 2019-04-10 Nippon Shinyaku Co., Ltd. Antisense nucleic acid
BR112016022499A2 (en) 2014-04-03 2017-08-15 Invictus Oncology Pvt Ltd SUPRAMOLECULAR COMBINATORY THERAPEUTIC PRODUCTS
US20170369872A1 (en) 2014-12-18 2017-12-28 Alnylam Pharmaceuticals, Inc. Reversir tm compounds
EP3297681B1 (en) 2015-05-19 2022-03-16 Akamara Therapeutics, Inc. Process for preparing supramolecular platinum-based compounds
EP3303286B1 (en) 2015-06-01 2023-10-04 Cedars-Sinai Medical Center Compounds that bind to rela of nf-kb for use in treating cancer
ES2741746T3 (en) 2015-06-19 2020-02-12 Novartis Ag Compounds and compositions to inhibit SHP2 activity
EP3310771B1 (en) 2015-06-19 2020-07-22 Novartis AG Compounds and compositions for inhibiting the activity of shp2
CN112625028A (en) 2015-06-19 2021-04-09 诺华股份有限公司 Compounds and compositions for inhibiting SHP2 activity
TW201722965A (en) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 Compounds for use in antibacterial applications
EP3653216A1 (en) 2015-09-30 2020-05-20 Sarepta Therapeutics, Inc. Methods for treating muscular dystrophy
US20180312534A1 (en) 2015-10-16 2018-11-01 Invictus Oncology Pvt. Ltd. Fluorescent anticancer platinum drugs
US10751306B2 (en) 2015-11-06 2020-08-25 The Johns Hopkins University Methods of treating liver fibrosis by administering 3-bromopyruvate
EP3449000A1 (en) 2016-04-29 2019-03-06 Sarepta Therapeutics, Inc. Oligonucleotide analogues targeting human lmna
WO2017191599A1 (en) 2016-05-04 2017-11-09 Genoscience Pharma Substituted 2, 4-diamino-quinoline derivatives for use in the treatment of proliferative diseases
MX2018015625A (en) 2016-06-14 2019-03-06 Novartis Ag Compounds and compositions for inhibiting the activity of shp2.
AU2017290231A1 (en) 2016-06-30 2019-02-07 Sarepta Therapeutics, Inc. Exon skipping oligomers for muscular dystrophy
CN117298290A (en) 2016-12-19 2023-12-29 萨勒普塔医疗公司 Exon-skipping oligomer conjugates for muscular dystrophy
WO2018118599A1 (en) 2016-12-19 2018-06-28 Sarepta Therapeutics, Inc. Exon skipping oligomer conjugates for muscular dystrophy
LT3554552T (en) 2016-12-19 2022-10-10 Sarepta Therapeutics, Inc. Exon skipping oligomer conjugates for muscular dystrophy
CA3060514A1 (en) 2017-04-20 2018-10-25 Atyr Pharma, Inc. Compositions and methods for treating lung inflammation
EA201991450A1 (en) 2017-09-22 2019-12-30 Сарепта Терапьютикс, Инк. OLIGOMER CONJUGATES FOR EXONISM SKIP IN MUSCULAR DYSTROPHY
WO2019067981A1 (en) 2017-09-28 2019-04-04 Sarepta Therapeutics, Inc. Combination therapies for treating muscular dystrophy
US20200254002A1 (en) 2017-09-28 2020-08-13 Sarepta Therapeutics, Inc. Combination therapies for treating muscular dystrophy
WO2019067975A1 (en) 2017-09-28 2019-04-04 Sarepta Therapeutics, Inc. Combination therapies for treating muscular dystrophy
US10765760B2 (en) 2018-05-29 2020-09-08 Sarepta Therapeutics, Inc. Exon skipping oligomer conjugates for muscular dystrophy
EP4219717A3 (en) 2018-06-13 2023-12-20 Sarepta Therapeutics, Inc. Exon skipping oligomers for muscular dystrophy
TW202020153A (en) 2018-07-27 2020-06-01 美商薩羅塔治療公司 Exon skipping oligomers for muscular dystrophy
EP3620164A1 (en) 2018-09-05 2020-03-11 Genoscience Pharma SAS Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins b (ctsb), l (ctsl) and d (ctsd) related diseases
US20200190516A1 (en) 2018-12-13 2020-06-18 Sarepta Therapeutics, Inc. Exon skipping oligomer conjugates for muscular dystropy
GB201821269D0 (en) 2018-12-28 2019-02-13 Nippon Shinyaku Co Ltd Myostatin signal inhibitor
US20220168261A1 (en) 2019-02-14 2022-06-02 Akamara Therapeutics, Inc. Compounds and methods for managing cancer through immune system
CA3134165A1 (en) 2019-03-28 2020-10-01 Sarepta Therapeutics, Inc. Methods for treating muscular dystrophy with casimersen
WO2020214763A1 (en) 2019-04-18 2020-10-22 Sarepta Therapeutics, Inc. Compositions for treating muscular dystrophy
WO2020257489A1 (en) 2019-06-19 2020-12-24 Sarepta Therapeutics, Inc. Methods for treating muscular dystrophy
MX2022007937A (en) 2019-12-26 2022-07-27 Nippon Shinyaku Co Ltd Antisense nucleic acid that induces skipping of exon 50.
IL295967A (en) 2020-02-28 2022-10-01 Nippon Shinyaku Co Ltd Antisense nucleic acid inducing skipping of exon 51
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
WO2023178230A1 (en) 2022-03-17 2023-09-21 Sarepta Therapeutics, Inc. Phosphorodiamidate morpholino oligomer conjugates
WO2024073570A1 (en) 2022-09-28 2024-04-04 Altos Labs, Inc. Expression of regeneration factors in aged/senescent cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3852037T2 (en) * 1987-07-29 1995-03-23 Liposome Co Inc METHOD FOR SEPARATING PARTICLES BY SIZE.
US5314695A (en) * 1990-11-13 1994-05-24 Corvas International, Inc. Tissue factor based prothrombin time reagent
AU663343B2 (en) * 1991-10-04 1995-10-05 Dade Behring Inc. Preparation of prothrombin time reagents from recombinant human tissue factor and purified natural and synthetic phospholipids

Also Published As

Publication number Publication date
WO1996014057A1 (en) 1996-05-17

Similar Documents

Publication Publication Date Title
IL115849A0 (en) Tangential filtration preparation of liposomal drugs and liposome product thereof
GB2313310B (en) Local delivery and monitoring of drugs
AU4990397A (en) Compound-loaded liposomes and methods for their preparation
PL322624A1 (en) Skin care composition containing retinoides and liposomes
AU2002301268A1 (en) Production of multivesicular liposomes
PL313386A1 (en) Novel pearls ensuring controllable drug release and pharmaceutic preparation containing them
EP0863748A4 (en) Liposomal compositions and methods of using them
SK63795A3 (en) Metallocene catalytic synthesis method of their preparation and use
AU1870695A (en) Windowed bag and process of making
EP0750910A4 (en) Liposome preparation
IL118469A (en) Naphthalene derivatives their preparation and intermediates thereof
ZA967654B (en) Electrodes and methods of preparation thereof
HUP0001266A3 (en) Lipid complexes and liposomes of highly insoluble platinum complexes
ZA986437B (en) Derivatives of acyl-piperazinyl-pyrimidines their preparation and application as medicaments
ZA956915B (en) Glycinamide derivatives processes for their preparation and medicines containing them
EP0748327A4 (en) Structure of a novel lipid a and methods utilizing same
PL319588A1 (en) Lyophilisate of a lipid complex of water-insoluble campotectins
ZA984266B (en) Pharmaceutical composition and process of preparation
AU4981896A (en) Liposome composition and method for administering liposome-loadable drugs
NZ300198A (en) Preparation of n-arylhydroxylamines and n-hetarylhydroxylamines
AU7428691A (en) Long-acting liposome peptide pharmaceutical products and processes for the preparation thereof
IL123322A0 (en) Tetrahydroquinolines their preparation and pharmaceutical compositions containing them
IL117668A0 (en) Preparation of polyesters
IL113811A0 (en) Preparation of 9-amino camptothecin
IL117078A0 (en) Substituted benzenesulfonylureas and -thioureas processes for their preparation their use for the production of pharmaceutical preparations and pharmaceutical preparations containing them