IL102288A0 - 7-azaisoindolinyl-quinolone-and naphthyridonecarboxylic acid derivatives,their preparation and antibacterial agents and feed additives containing them - Google Patents

7-azaisoindolinyl-quinolone-and naphthyridonecarboxylic acid derivatives,their preparation and antibacterial agents and feed additives containing them

Info

Publication number
IL102288A0
IL102288A0 IL102288A IL10228892A IL102288A0 IL 102288 A0 IL102288 A0 IL 102288A0 IL 102288 A IL102288 A IL 102288A IL 10228892 A IL10228892 A IL 10228892A IL 102288 A0 IL102288 A0 IL 102288A0
Authority
IL
Israel
Prior art keywords
azaisoindolinyl
quinolone
preparation
acid derivatives
antibacterial agents
Prior art date
Application number
IL102288A
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL102288A0 publication Critical patent/IL102288A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
IL102288A 1991-06-27 1992-06-24 7-azaisoindolinyl-quinolone-and naphthyridonecarboxylic acid derivatives,their preparation and antibacterial agents and feed additives containing them IL102288A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4121214A DE4121214A1 (en) 1991-06-27 1991-06-27 7-AZAISOINDOLINYL CHINOLONE AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES

Publications (1)

Publication Number Publication Date
IL102288A0 true IL102288A0 (en) 1993-01-14

Family

ID=6434855

Family Applications (1)

Application Number Title Priority Date Filing Date
IL102288A IL102288A0 (en) 1991-06-27 1992-06-24 7-azaisoindolinyl-quinolone-and naphthyridonecarboxylic acid derivatives,their preparation and antibacterial agents and feed additives containing them

Country Status (17)

Country Link
US (2) US5312823A (en)
EP (1) EP0520277A3 (en)
JP (1) JPH05213947A (en)
KR (1) KR930000514A (en)
CN (1) CN1068114A (en)
AU (2) AU647627B2 (en)
CA (1) CA2072207A1 (en)
CZ (1) CZ192892A3 (en)
DE (1) DE4121214A1 (en)
FI (1) FI922953A (en)
HU (1) HUT61545A (en)
IE (1) IE922099A1 (en)
IL (1) IL102288A0 (en)
MX (1) MX9203228A (en)
NO (1) NO922291L (en)
TW (1) TW209218B (en)
ZA (1) ZA924743B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4121214A1 (en) * 1991-06-27 1993-01-14 Bayer Ag 7-AZAISOINDOLINYL CHINOLONE AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES
AU4272793A (en) * 1993-04-24 1994-11-21 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
DE4339134A1 (en) * 1993-11-16 1995-05-18 Bayer Ag 1- (2-fluorocyclopropyl) quinolone and naphthyridonecarboxylic acid derivatives
KR950018003A (en) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 Novel quinolone derivatives and methods for their preparation
DE4427530A1 (en) * 1994-08-04 1996-02-08 Bayer Ag New 7-tri:cyclic amino-quinolone or naphthyridone derivs
DE4435479A1 (en) * 1994-10-04 1996-04-11 Bayer Ag Quinolone and naphthyridonecarboxylic acid derivatives
DE19500792A1 (en) * 1995-01-13 1996-07-18 Bayer Ag Quinolone and naphthyridonecarboxylic acid derivatives
US6608081B2 (en) 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
EP1358185A2 (en) 2001-02-07 2003-11-05 Ortho-Mcneil Pharmaceutical, Inc. Pyridoarylphenyl oxazolidinone antibacterials, and related compositions and methods
EP2305696A3 (en) 2005-07-25 2011-10-12 Intermune, Inc. Macrocyclic inhibitors of Hepatitis C virus replication
FR2891274B1 (en) * 2005-09-27 2007-11-23 Pierre Fabre Medicament Sa PROCESS FOR PREPARING (3-CHLORO-4-FLUORO-PHENYL) - (4-FLUORO-4 - {[(5-METHYL-PYRIMIDIN-2-YLMETHYL) -AMINO] -METHYL] -PIPERIDIN-1-YL) METHANONE AND NEW INTERMEDIATE PYRIMIDINE DERIVATIVES.
CN102443015A (en) * 2010-10-13 2012-05-09 南京明生医药技术有限公司 7-substituted quinoline carboxylic acid derivatives, preparation method and application thereof in antibiosis and antituberculosis
AR095079A1 (en) 2013-03-12 2015-09-16 Hoffmann La Roche DERIVATIVES OF OCTAHIDRO-PIRROLO [3,4-C] -PIRROL AND PIRIDINA-FENILO
CN103351348A (en) * 2013-07-15 2013-10-16 黄河三角洲京博化工研究院有限公司 Synthetic method for 2-methylamino pyrimidine hydrochloride
PL3074400T3 (en) 2013-11-26 2018-03-30 F.Hoffmann-La Roche Ag Octahydro-cyclobuta [1,2-c;3,4-c']dipyrrole derivatives as autotaxin inhibitors
EP3527569B1 (en) 2014-02-03 2021-08-25 Vitae Pharmaceuticals, LLC Dihydropyrrolopyridine inhibitors of ror-gamma for use in treating drye eye
MA50635A (en) 2014-03-26 2020-08-12 Hoffmann La Roche NEW BICYCLIC COMPOUNDS AS INHIBITORS OF AUTOTAXIN (ATX) AND LYSOPHOSPHATIDIC ACID PRODUCTION
WO2016046837A1 (en) * 2014-09-22 2016-03-31 Cadila Healthcare Limited An improved process for preparation of pyrrolo[3,4- c] pyrrole compounds and intermediates thereof
PT3207043T (en) 2014-10-14 2019-03-25 Vitae Pharmaceuticals Llc Dihydropyrrolopyridine inhibitors of ror-gamma
US9663515B2 (en) 2014-11-05 2017-05-30 Vitae Pharmaceuticals, Inc. Dihydropyrrolopyridine inhibitors of ROR-gamma
US9845308B2 (en) 2014-11-05 2017-12-19 Vitae Pharmaceuticals, Inc. Isoindoline inhibitors of ROR-gamma
WO2016183741A1 (en) 2015-05-15 2016-11-24 Merck Sharp & Dohme Corp. Pyrimidinone amide compounds as pde2 inhibitors
EP3331876B1 (en) 2015-08-05 2020-10-07 Vitae Pharmaceuticals, LLC Modulators of ror-gamma
PE20180479A1 (en) 2015-09-04 2018-03-07 Hoffmann La Roche NEW DERIVATIVES OF PHENOXYMETHYL
CA2984585A1 (en) 2015-09-24 2017-03-30 F. Hoffmann-La Roche Ag New bicyclic compounds as dual atx/ca inhibitors
CA2983782A1 (en) 2015-09-24 2017-03-30 F. Hoffmann-La Roche Ag Bicyclic compounds as atx inhibitors
RU2724899C2 (en) * 2015-09-24 2020-06-26 Ф. Хоффманн-Ля Рош Аг New bicyclic compounds as dual inhibitors of atx/ca
CN108463458B (en) 2015-11-20 2022-02-01 生命医药有限责任公司 Modulators of ROR-gamma
TW202220968A (en) 2016-01-29 2022-06-01 美商維它藥物有限責任公司 Modulators of ror-gamma
US9481674B1 (en) 2016-06-10 2016-11-01 Vitae Pharmaceuticals, Inc. Dihydropyrrolopyridine inhibitors of ROR-gamma
JP7090099B2 (en) 2017-03-16 2022-06-23 エフ．ホフマン－ラ ロシュ アーゲー A novel bicyclic compound as an ATX inhibitor
CN110392679B (en) 2017-03-16 2023-04-07 豪夫迈·罗氏有限公司 Heterocyclic compounds useful as dual ATX/CA inhibitors
TWI772389B (en) 2017-03-20 2022-08-01 美商佛瑪治療公司 Pyrrolopyrrole compositions as pyruvate kinase (pkr) activators
UA126583C2 (en) 2017-07-24 2022-11-02 Вітае Фармасьютікалс, Ллс INHIBITORS OF ROR<font face="Symbol">g</font>
WO2019018975A1 (en) 2017-07-24 2019-01-31 Vitae Pharmaceuticals, Inc. Inhibitors of ror gamma
CN113226356A (en) 2018-09-19 2021-08-06 福马治疗股份有限公司 Activating pyruvate kinase R
WO2020061378A1 (en) 2018-09-19 2020-03-26 Forma Therapeutics, Inc. Treating sickle cell disease with a pyruvate kinase r activating compound
CN109942488A (en) * 2019-04-04 2019-06-28 山东省联合农药工业有限公司 A kind of quinoline carboxylic acid ester's compound and preparation method thereof and purposes
CN113307768B (en) * 2021-04-29 2023-12-12 中国农业科学院兰州畜牧与兽药研究所 Quinolone derivative and preparation method and application thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
NZ208470A (en) * 1983-07-18 1988-06-30 Abbott Lab 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
EP0154780B1 (en) * 1984-01-26 1990-04-11 Abbott Laboratories Quinoline antibacterial compounds
DE3420743A1 (en) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-AMINO-1-CYCLOPROPYL-6,8-DIHALOGEN-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS
WO1989005643A1 (en) * 1987-12-18 1989-06-29 Pfizer Inc. Heterocyclic-substituted quinoline-carboxylic acids
JPH0262875A (en) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd Novel isoindoline derivative
DE3906365A1 (en) * 1988-07-15 1990-01-18 Bayer Ag 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM
KR910009330B1 (en) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 Antimicrobial quinoline compounds and the preparation process thereof
KR910009333B1 (en) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 Antimicrobial quinoline compounds and the preparation process thereof
DE4121214A1 (en) * 1991-06-27 1993-01-14 Bayer Ag 7-AZAISOINDOLINYL CHINOLONE AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES
DE4123918A1 (en) * 1991-07-19 1993-01-21 Bayer Ag 8-VINYL AND 8-ETHINYL-CHINOLON CARBONIC ACIDS
KR930703292A (en) * 1991-12-27 1993-11-29 쿠사이 요시히로 Novel quinolone derivatives or salts thereof and antimicrobial agents containing the compounds
TW209865B (en) * 1992-01-10 1993-07-21 Bayer Ag

Also Published As

Publication number Publication date
TW209218B (en) 1993-07-11
US5312823A (en) 1994-05-17
AU647627B2 (en) 1994-03-24
FI922953A0 (en) 1992-06-25
AU1803092A (en) 1993-01-07
IE922099A1 (en) 1992-12-30
DE4121214A1 (en) 1993-01-14
MX9203228A (en) 1992-12-01
EP0520277A2 (en) 1992-12-30
US5371090A (en) 1994-12-06
ZA924743B (en) 1993-03-31
JPH05213947A (en) 1993-08-24
FI922953A (en) 1992-12-28
NO922291D0 (en) 1992-06-11
CN1068114A (en) 1993-01-20
CZ192892A3 (en) 1993-01-13
KR930000514A (en) 1993-01-15
HUT61545A (en) 1993-01-28
EP0520277A3 (en) 1993-01-13
HU9202145D0 (en) 1992-10-28
AU5304094A (en) 1994-03-03
NO922291L (en) 1992-12-28
CA2072207A1 (en) 1992-12-28

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