ID18010A - MODIFIED OLIGOSAKARIDA - Google Patents

MODIFIED OLIGOSAKARIDA

Info

Publication number
ID18010A
ID18010A IDP972766A ID972766A ID18010A ID 18010 A ID18010 A ID 18010A ID P972766 A IDP972766 A ID P972766A ID 972766 A ID972766 A ID 972766A ID 18010 A ID18010 A ID 18010A
Authority
ID
Indonesia
Prior art keywords
oligosakarida
modified
modified oligosakarida
Prior art date
Application number
IDP972766A
Other languages
Indonesian (id)
Inventor
Gebfard Dr Thoma
Rolf Dr Banteli
Willy Dr Kinzy
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ID18010A publication Critical patent/ID18010A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06Aminosugars
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IDP972766A 1996-08-08 1997-08-08 MODIFIED OLIGOSAKARIDA ID18010A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96810527 1996-08-08
EP96810526 1996-08-08
EP96810636 1996-09-26

Publications (1)

Publication Number Publication Date
ID18010A true ID18010A (en) 1998-02-19

Family

ID=27237868

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP972766A ID18010A (en) 1996-08-08 1997-08-08 MODIFIED OLIGOSAKARIDA

Country Status (19)

Country Link
EP (1) EP0920437A1 (en)
JP (1) JP2000516224A (en)
KR (1) KR20000029862A (en)
CN (1) CN1227563A (en)
AR (1) AR008283A1 (en)
AU (1) AU720381B2 (en)
BR (1) BR9711117A (en)
CA (1) CA2260854A1 (en)
CO (1) CO4900075A1 (en)
CZ (1) CZ39099A3 (en)
ID (1) ID18010A (en)
IL (1) IL127908A0 (en)
NO (1) NO990497L (en)
NZ (1) NZ334048A (en)
PE (1) PE99298A1 (en)
PL (1) PL331286A1 (en)
SK (1) SK15699A3 (en)
TR (1) TR199900245T2 (en)
WO (1) WO1998006730A1 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888984A (en) * 1994-05-12 1999-03-30 Dermal Research Laboratories, Inc. Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same
WO2000044367A2 (en) * 1999-02-01 2000-08-03 Dermal Research Laboratories, Inc. A pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same
US7879824B2 (en) 2001-07-31 2011-02-01 Dermal Research Laboratories, Inc. Methods of preventing or treating diseases and conditions using complex carbohydrates
CA2490703A1 (en) * 2002-07-03 2004-01-15 Glycomimetics, Inc. Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis
DE60329511D1 (en) 2002-10-11 2009-11-12 Astellas Pharma Europ B V GLUCOSE BASE COMPOSITIONS WITH AFFINITY FOR P-SELECTIN
WO2005054264A2 (en) * 2003-11-19 2005-06-16 Glycomimetics, Inc. Glycomimetic antagonists for both e- and p-selectins
US20090036386A1 (en) * 2005-05-25 2009-02-05 Glycomimetics, Inc Heterobifunctional compounds for selectin inhibition
CN101287741B (en) 2005-09-02 2014-05-07 糖模拟物有限公司 Heterobifunctional pan-selectin inhibitors
AU2008216794A1 (en) * 2007-02-09 2008-08-21 Glycomimetics, Inc. Methods of use of glycomimetics with replacements for hexoses and N-acetyl hexosamines
US9486497B2 (en) 2007-12-10 2016-11-08 The University Of Queensland Treatment of immunocompromised conditions
WO2009126556A1 (en) 2008-04-08 2009-10-15 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
WO2012037034A1 (en) 2010-09-14 2012-03-22 Glycomimetics, Inc. E-selectin antagonists
US9109002B2 (en) 2011-12-22 2015-08-18 Glycomimetics, Inc. E-selectin antagonist compounds, compositions, and methods of use
ES2668045T3 (en) 2012-12-07 2018-05-16 Glycomimetics, Inc. Compounds, compositions and methods that use E-selectin antagonists for the mobilization of hematopoietic cells
ES2754549T3 (en) 2014-12-03 2020-04-20 Glycomimetics Inc Heterobifunctional inhibitors of E-selectins and CXCR4 chemokine receptors
EP3405473A1 (en) 2016-01-22 2018-11-28 GlycoMimetics, Inc. Glycomimetic inhibitors of pa-il and pa-iil lectins
WO2017151708A1 (en) 2016-03-02 2017-09-08 Glycomimetics, Inc. Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
EP3497131B1 (en) 2016-08-08 2022-03-09 GlycoMimetics, Inc. Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4.
EP3522931A1 (en) 2016-10-07 2019-08-14 GlycoMimetics, Inc. Highly potent multimeric e-selectin antagonists
JP7272956B2 (en) 2017-03-15 2023-05-12 グリコミメティクス, インコーポレイテッド Galactopyranosyl-cyclohexyl derivatives as E-selectin antagonists
JP7275131B2 (en) 2017-11-30 2023-05-17 グリコミメティクス, インコーポレイテッド Methods of mobilizing bone marrow-infiltrating lymphocytes and uses thereof
EP3732186A1 (en) 2017-12-29 2020-11-04 GlycoMimetics, Inc. Heterobifunctional inhibitors of e-selectin and galectin-3
CN108299525B (en) * 2018-01-05 2021-03-26 佛山科学技术学院 Method for synthesizing Lewis oligose-X
AU2019230013A1 (en) 2018-03-05 2020-09-10 Glycomimetics, Inc. Methods for treating acute myeloid leukemia and related conditions
WO2020139962A1 (en) 2018-12-27 2020-07-02 Glycomimetics, Inc. Heterobifunctional inhibitors of e-selectin and galectin-3
CN109762032A (en) * 2019-01-16 2019-05-17 天津科技大学 A kind of sulfonated lewis X trisaccharide and its synthetic method and application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023031A1 (en) * 1992-05-08 1993-11-25 The Biomembrane Institute Multivalent mimetics and peptide mimetics for blocking carbohydrate-dependent cellular interaction and for eliciting anticarbohydrate t-cell response
WO1994020514A1 (en) * 1993-03-04 1994-09-15 Mect Corporation Lewis-associated compound, process for producing the same, and anti-inflammatory
SK141695A3 (en) * 1993-05-14 1996-10-02 Cytel Corp Analogous compound sialyl lex, pharmaceutical agent containing this compound and method of preparation of lactoseammoniacal salt
CN1176644A (en) * 1994-12-28 1998-03-18 住友制药株式会社 Lewis X derivative and process for producing the same

Also Published As

Publication number Publication date
NO990497D0 (en) 1999-02-03
KR20000029862A (en) 2000-05-25
IL127908A0 (en) 1999-11-30
TR199900245T2 (en) 1999-05-21
EP0920437A1 (en) 1999-06-09
CN1227563A (en) 1999-09-01
PE99298A1 (en) 1999-01-21
AU4378897A (en) 1998-03-06
AR008283A1 (en) 1999-12-29
CA2260854A1 (en) 1998-02-19
NO990497L (en) 1999-03-24
BR9711117A (en) 1999-09-08
JP2000516224A (en) 2000-12-05
CO4900075A1 (en) 2000-03-27
PL331286A1 (en) 1999-07-05
AU720381B2 (en) 2000-06-01
SK15699A3 (en) 1999-07-12
NZ334048A (en) 2000-05-26
WO1998006730A1 (en) 1998-02-19
CZ39099A3 (en) 1999-05-12

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