HUP0700809A2 - Racemisation process for producing methyl (r,s)-(+)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4h)-acetate hydrogene sulfate intermediate - Google Patents

Racemisation process for producing methyl (r,s)-(+)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4h)-acetate hydrogene sulfate intermediate

Info

Publication number
HUP0700809A2
HUP0700809A2 HU0700809A HUP0700809A HUP0700809A2 HU P0700809 A2 HUP0700809 A2 HU P0700809A2 HU 0700809 A HU0700809 A HU 0700809A HU P0700809 A HUP0700809 A HU P0700809A HU P0700809 A2 HUP0700809 A2 HU P0700809A2
Authority
HU
Hungary
Prior art keywords
dihydrothieno
pyridin
chlorophenyl
alpha
acetate
Prior art date
Application number
HU0700809A
Other languages
Hungarian (hu)
Inventor
Sandor Garadnay
Jozsef Neu
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Priority to HU0700809A priority Critical patent/HUP0700809A2/en
Publication of HU0700809D0 publication Critical patent/HU0700809D0/en
Priority to PCT/HU2008/000148 priority patent/WO2009077797A1/en
Publication of HUP0700809A2 publication Critical patent/HUP0700809A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
HU0700809A 2007-12-14 2007-12-14 Racemisation process for producing methyl (r,s)-(+)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4h)-acetate hydrogene sulfate intermediate HUP0700809A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU0700809A HUP0700809A2 (en) 2007-12-14 2007-12-14 Racemisation process for producing methyl (r,s)-(+)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4h)-acetate hydrogene sulfate intermediate
PCT/HU2008/000148 WO2009077797A1 (en) 2007-12-14 2008-12-11 Racemization process for the preparation of an intermediate of clopidogrel hydrogen sulphate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0700809A HUP0700809A2 (en) 2007-12-14 2007-12-14 Racemisation process for producing methyl (r,s)-(+)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4h)-acetate hydrogene sulfate intermediate

Publications (2)

Publication Number Publication Date
HU0700809D0 HU0700809D0 (en) 2008-02-28
HUP0700809A2 true HUP0700809A2 (en) 2009-11-30

Family

ID=89987939

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0700809A HUP0700809A2 (en) 2007-12-14 2007-12-14 Racemisation process for producing methyl (r,s)-(+)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4h)-acetate hydrogene sulfate intermediate

Country Status (2)

Country Link
HU (1) HUP0700809A2 (en)
WO (1) WO2009077797A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111166745A (en) * 2020-01-19 2020-05-19 成都施贝康生物医药科技有限公司 Composition containing racemic oxypyramine or salt thereof and application

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL166593A0 (en) * 2002-08-02 2006-01-15 Racemization and enantiomer separation of clopidogrel

Also Published As

Publication number Publication date
WO2009077797A1 (en) 2009-06-25
HU0700809D0 (en) 2008-02-28

Similar Documents

Publication Publication Date Title
WO2007125544A3 (en) Process for the preparation of polymorphic forms of clopidogrel hydrogen sulfate
IL185510A0 (en) Fused thieno [2,3-b] pyridine and thiazolo [5,4-b] pyridine compounds for inhibiting ksp kinesin activity
IL189667A0 (en) 4-amino-thieno[3,2-c]pyridine-7-carboxylic acid derivatives
IL177805A0 (en) A method for preparing thieno[3,2-c]pyridine derivatives
HK1122808A1 (en) Preparation and use of tetrahydropyrrolo [3, 2-c]t pyridin-4-one derivatives for treatment of obesitty, psychiatric and neurological disorders
PL2112155T3 (en) Hydrogensulfate salt of 2-acetoxy-5-(a-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine and its preparation
HK1159628A1 (en) Thieno[3,2-c]pyridine derivatives as kinase inhibitors for use in the treatment of cancer [32- c]
IL181387A0 (en) Fused tricyclic derivatives for the treatment of psychotic disorders
SI1513846T1 (en) Process of preparation of olanzapine form i
EP1651646A4 (en) A novel process for the manufacture of (+)-(s)-clopidogrel bisulfate form-i
HU0600194D0 (en) Process for producing (s)-(+)-methyl-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4h)-acetate hidrogen sulfate polimorph i
ZA200608569B (en) Polymorphic forms of methyl (+)-(S)-alpha- (2-chlorophenyl)-6, 7-dinydrothieno[3,2-C] pyridine-5(4H) acetate hydrobromide, clopidrogel hydrobromide
PL382055A1 (en) Production method of crystalline form of clopidogrel 1 hydrogen sulphate
HU0700809D0 (en) Racemisation process for producing methyl (r,s)-(+)-alpha-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4h)-acetate hydrogene sulfate intermediate
UA84335C2 (en) Clopidogrel salt and polymorphic forms thereof
IL218132B (en) Crystalline forms of 4,5,6,7-tetrahydro-11-methoxy-2-[(4-methyl-1-piperazinyl)methyl]-1h-cyclopenta[a]pyrrolo[3,4-c]carbazole-1,3(2h)-dione and pharmaceutical compositions comprising them
ZA201000627B (en) 2-(2-oxoindoline-3-ylidene)methyl-5-(2-hydroxy-3-morpholin-4-yl-propyl)-6,7-dihydro-1h-pyrrol[3,2-c]pyridine-4(5h)-one compounds and use as protein kinase inhibitors
PL354642A1 (en) Method of manufacture of alanzapine, new derivative of n-demethyl olanzapine and method of manufacture of new derivative of n-demethyl olanzapine
WO2007087555A3 (en) Novel polymorph 'form e ' of olanzapine (2-methyl-4- (4-methyl-1-piperazinyl) -10h-thieno [2, 3-b] [1, 5] benzodiazepine) and preparation of the anhydrous non-solvated crystalline polymorphic 'form i' of olanzapine from the polymorphic olanzapine 'form e'
SG113595A1 (en) New benzo[b]chromeno-naphthyridin-7-one and pyrano[2',3':7,8] quino[2,3-b]quinoxalin-7-one compounds, process for their preparation and pharmaceutical compositions containing them
PL380849A1 (en) Crystalline form of racemic methyl 0 - (2-chlorophenyl) - 6, 7 - dihydrothiene [3, 2 - c] pyridil -5 (4H) - acetate, method for its manufacture and its application
WO2008108742A3 (en) Polymorphic forms of clopidogrel hydrobromide
EA201290535A1 (en) METHOD FOR OBTAINING PHARMACEUTICAL COMPOUNDS AND INTERMEDIATE COMPOUNDS
WO2005003138A3 (en) Process for the preparation of amorphous form of a platelet aggregation inhibitor drug
ZA200707302B (en) Fused thieno [2,3-B] pyridine and thiazolo [5,4-B] pyridine compounds for inhibiting KSP kinesin activity

Legal Events

Date Code Title Description
FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished