HUP0002106A2 - Transz-5-klór-2,3,3a,12b-tetrahidro-2-metil-1H-dibenz-[2,3:6,7]oxepino[4,5-c]pirrol aromás szulfonátjai és az ezt tartalmazó gyógyszerkészítmények - Google Patents

Transz-5-klór-2,3,3a,12b-tetrahidro-2-metil-1H-dibenz-[2,3:6,7]oxepino[4,5-c]pirrol aromás szulfonátjai és az ezt tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0002106A2
HUP0002106A2 HU0002106A HUP0002106A HUP0002106A2 HU P0002106 A2 HUP0002106 A2 HU P0002106A2 HU 0002106 A HU0002106 A HU 0002106A HU P0002106 A HUP0002106 A HU P0002106A HU P0002106 A2 HUP0002106 A2 HU P0002106A2
Authority
HU
Hungary
Prior art keywords
oxepino
dibenz
pyrrole
tetrahydro
trans
Prior art date
Application number
HU0002106A
Other languages
English (en)
Inventor
Gerardus Johannes Heeres
Franciscus Hermanus Antonius Adreana Van Bakel
Original Assignee
Akzo Nobel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.
Publication of HUP0002106A2 publication Critical patent/HUP0002106A2/hu
Publication of HUP0002106A3 publication Critical patent/HUP0002106A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A találmány a CNS-antidepresszáns transz-5-klór-2,3,3a,12b-tet-rahidro-2-metil-1H-dibenz[2,3:6,7]oxepino[4,5-c]pirrol és egy sóképzőszer sójára vonatkozik, amelyben a sóképző szer egy aromás szulfonsav.A találmány szerinti só előnyösen vízben oldhatatlan és kristályos,ezért injekciós depókészítmények előállítására alkalmazható. Ó
HU0002106A 1997-05-26 1998-05-19 Aromatic sulfonates of trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1h-dibenz-[2,3:6,7]oxepino[4,5-c]pyrrole and pharmaceutical compositions containing it HUP0002106A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97201596 1997-05-26
PCT/EP1998/003022 WO1998054186A1 (en) 1997-05-26 1998-05-19 Salts of aromatic sulphonic acids

Publications (2)

Publication Number Publication Date
HUP0002106A2 true HUP0002106A2 (hu) 2000-11-28
HUP0002106A3 HUP0002106A3 (en) 2001-11-28

Family

ID=8228372

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0002106A HUP0002106A3 (en) 1997-05-26 1998-05-19 Aromatic sulfonates of trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1h-dibenz-[2,3:6,7]oxepino[4,5-c]pyrrole and pharmaceutical compositions containing it

Country Status (12)

Country Link
EP (1) EP0984968A1 (hu)
JP (1) JP2001526702A (hu)
KR (1) KR20010012985A (hu)
CN (1) CN1257504A (hu)
AU (1) AU7767598A (hu)
BR (1) BR9809162A (hu)
CA (1) CA2290070A1 (hu)
HU (1) HUP0002106A3 (hu)
NO (1) NO995770D0 (hu)
PL (1) PL337027A1 (hu)
TR (1) TR199902727T2 (hu)
WO (1) WO1998054186A1 (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2295058B1 (en) 2001-10-30 2013-09-04 Novartis AG Depot formulations of iloperidone with a polymer
HRP20020440B1 (en) 2002-05-21 2008-02-29 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 1-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof
HRP20020452A2 (en) 2002-05-23 2004-02-29 Pliva D D 1,2-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediates for preparation thereof
GB0216416D0 (en) 2002-07-15 2002-08-21 Novartis Ag Organic compounds
KR20070084123A (ko) * 2004-10-15 2007-08-24 엔.브이.오가논 양극성 장애 및 관련 증상의 치료
RU2012102247A (ru) 2009-06-24 2013-07-27 Мсд Осс Б.В. Инъекционные композиции, содержащие асенапин и способ лечения с их применением
ITMI20110734A1 (it) 2011-05-02 2012-11-03 Olon Spa Sali cristallini di asenapina
EP2524919A1 (en) 2011-05-17 2012-11-21 Sandoz AG Novel crystalline salts of Asenapine with organic Di-acids and Tri-acids
EP2524921A1 (en) 2011-05-17 2012-11-21 Sandoz AG Novel Crystalline Salts of Asenapine
EP2524920A1 (en) 2011-05-17 2012-11-21 Sandoz AG Novel Crystalline Asenapine Hydrochloride Salt Forms
AU2017384392B2 (en) 2016-12-20 2023-05-25 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene
PL3338768T3 (pl) 2016-12-20 2020-05-18 Lts Lohmann Therapie-Systeme Ag Transdermalny system terapeutyczny zawierający asenapinę
JP2020525545A (ja) 2017-06-26 2020-08-27 エルテーエス ローマン テラピー−ジステーメ アーゲー アセナピンおよびシリコーンアクリルハイブリッドポリマーを含有する経皮治療システム
MX2020014286A (es) 2018-06-20 2021-03-25 Lts Lohmann Therapie Systeme Ag Sistema terapeutico transdermico que contiene asenapina.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.

Also Published As

Publication number Publication date
KR20010012985A (ko) 2001-02-26
NO995770L (no) 1999-11-25
AU7767598A (en) 1998-12-30
BR9809162A (pt) 2000-08-01
CA2290070A1 (en) 1998-12-03
TR199902727T2 (xx) 2000-07-21
WO1998054186A1 (en) 1998-12-03
PL337027A1 (en) 2000-07-31
EP0984968A1 (en) 2000-03-15
NO995770D0 (no) 1999-11-25
JP2001526702A (ja) 2001-12-18
CN1257504A (zh) 2000-06-21
HUP0002106A3 (en) 2001-11-28

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