HK1169455A1 - 阿爾茨海默病的診斷和治療 - Google Patents

阿爾茨海默病的診斷和治療

Info

Publication number
HK1169455A1
HK1169455A1 HK12110195.8A HK12110195A HK1169455A1 HK 1169455 A1 HK1169455 A1 HK 1169455A1 HK 12110195 A HK12110195 A HK 12110195A HK 1169455 A1 HK1169455 A1 HK 1169455A1
Authority
HK
Hong Kong
Prior art keywords
diagnosis
treatment
alzheimers disease
alzheimers
disease
Prior art date
Application number
HK12110195.8A
Other languages
English (en)
Inventor
Julie Williams
Michael John Owen
Original Assignee
Univ College Cardiff Consultants Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0911539A external-priority patent/GB0911539D0/en
Priority claimed from GB0913357A external-priority patent/GB0913357D0/en
Priority claimed from GB0917326A external-priority patent/GB0917326D0/en
Application filed by Univ College Cardiff Consultants Ltd filed Critical Univ College Cardiff Consultants Ltd
Publication of HK1169455A1 publication Critical patent/HK1169455A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/775Apolipopeptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK12110195.8A 2009-07-03 2012-10-16 阿爾茨海默病的診斷和治療 HK1169455A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0911539A GB0911539D0 (en) 2009-07-03 2009-07-03 Diagnosis of alzheimer's disease
GB0913357A GB0913357D0 (en) 2009-07-31 2009-07-31 Diagnosis of alzheimer's disease
GB0917326A GB0917326D0 (en) 2009-10-03 2009-10-03 Diagnosis of alzheimer's disease
PCT/GB2010/001208 WO2011001135A2 (en) 2009-07-03 2010-06-22 Diagnosis and treatment of alzheimer's disease

Publications (1)

Publication Number Publication Date
HK1169455A1 true HK1169455A1 (zh) 2013-01-25

Family

ID=43014386

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12110195.8A HK1169455A1 (zh) 2009-07-03 2012-10-16 阿爾茨海默病的診斷和治療

Country Status (9)

Country Link
US (3) US20120122703A1 (zh)
EP (2) EP2449134B1 (zh)
JP (2) JP5917395B2 (zh)
CN (2) CN102471800A (zh)
AU (1) AU2010267835C1 (zh)
CA (1) CA2766876C (zh)
HK (1) HK1169455A1 (zh)
NZ (1) NZ596614A (zh)
WO (1) WO2011001135A2 (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010267835C1 (en) * 2009-07-03 2015-02-26 University College Cardiff Consultants Limited Diagnosis and treatment of Alzheimer's disease
WO2011024035A1 (en) * 2009-08-27 2011-03-03 Institut Pasteur De Lille Method for determining the risk of occurrence of alzheimer's disease
GB201212334D0 (en) * 2012-07-11 2012-08-22 Warwick The Therapeutic targets for alzheimers disease
CN104102839B (zh) * 2013-11-16 2017-10-27 西安电子科技大学 一种基于多尺度网格曲面形状特征的阿尔茨海默病脑皮层自动分类方法
CN105969885A (zh) * 2016-06-24 2016-09-28 江苏雄鸣医药科技有限公司 一种阿尔兹海默症的基因诊断试剂盒
CN106978475A (zh) * 2016-08-17 2017-07-25 上海易瑞生物科技有限公司 一种阿尔茨海默氏病易感基因检测分型试剂盒及其应用
CN106290823A (zh) * 2016-10-18 2017-01-04 上海凯璟生物科技有限公司 一种阿尔兹海默综合症标志物abca7检测试剂盒和制备方法
US11725232B2 (en) * 2016-10-31 2023-08-15 The Hong Kong University Of Science And Technology Compositions, methods and kits for detection of genetic variants for alzheimer's disease
US20210293794A1 (en) * 2017-02-24 2021-09-23 University Of Hawii Cancer Center Metabolic biomarkers for the identification and characterization of alzheimers disease
WO2018212371A1 (ko) * 2017-05-17 2018-11-22 조선대학교산학협력단 알츠하이머병 위험도와 관련된 apoe 프로모터 단일염기변이 및 이것의 용도
KR101933847B1 (ko) 2017-05-15 2018-12-28 조선대학교산학협력단 알츠하이머병 위험도와 관련된 apoe 프로모터 단일염기변이 및 이것의 용도
JP7399465B2 (ja) * 2017-05-15 2023-12-18 インフォメディテック・カンパニー,リミテッド アルツハイマー病の危険性と関連するapoeプロモーターの一塩基多型およびその使用
WO2019178167A1 (en) * 2018-03-13 2019-09-19 I2Dx, Inc. Electronic delivery of information in personalized medicine
JP2021524741A (ja) * 2018-05-18 2021-09-16 アナベックス ライフ サイエンス コーポレイション レスポンダ選択および治療の最適化されたsigma−1アゴニスト方法
CN110607364B (zh) * 2019-11-01 2023-04-28 北京中医药大学 通过检测snp位点确定等位基因的基因型的方法
KR20230134755A (ko) * 2022-03-15 2023-09-22 사회복지법인 삼성생명공익재단 유럽 인구 데이터 기반 알츠하이머병 치매의 발병 위험군 또는 조기 증상 발현 위험군, 기억상실형 경도인지장애의 발병 위험군 및/또는 아밀로이드β 침착에 대한 PET 양성 위험군을 예측하기 위한 정보를 제공하는 방법
CN114736963B (zh) * 2022-05-25 2023-03-24 首都医科大学宣武医院 一种用于预测阿尔茨海默病发病风险的物质的组合、试剂盒及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2765591B1 (fr) * 1997-07-01 2002-08-09 Pasteur Institut Procede de diagnostic de la maladie d'alzheimer
WO2006138716A2 (en) * 2005-06-17 2006-12-28 Brt Laboratories, Inc. Thermodynamically defined gene specific primers
JP2007166962A (ja) * 2005-12-21 2007-07-05 Japan Health Science Foundation アルツハイマー病の予測または診断の方法
WO2008085601A2 (en) * 2006-11-02 2008-07-17 Genizon Biosciences Inc. Genemap of the human genes associated with asthma disease
CN101679970A (zh) * 2007-04-17 2010-03-24 参天制药株式会社 青光眼发病风险的判定方法
AU2010267835C1 (en) * 2009-07-03 2015-02-26 University College Cardiff Consultants Limited Diagnosis and treatment of Alzheimer's disease

Also Published As

Publication number Publication date
US20150119264A1 (en) 2015-04-30
CN102471800A (zh) 2012-05-23
EP2449134A2 (en) 2012-05-09
CN103409511A (zh) 2013-11-27
US20120122703A1 (en) 2012-05-17
JP2014012007A (ja) 2014-01-23
CA2766876A1 (en) 2011-01-06
CA2766876C (en) 2020-01-28
WO2011001135A9 (en) 2011-02-24
EP2891723A1 (en) 2015-07-08
WO2011001135A2 (en) 2011-01-06
JP5917395B2 (ja) 2016-05-11
AU2010267835C1 (en) 2015-02-26
EP2891723B1 (en) 2017-10-04
JP2012531195A (ja) 2012-12-10
WO2011001135A3 (en) 2011-06-30
NZ596614A (en) 2012-11-30
EP2449134B1 (en) 2016-07-27
AU2010267835B2 (en) 2014-11-06
JP5917460B2 (ja) 2016-05-18
AU2010267835A1 (en) 2011-12-15
US20130288906A1 (en) 2013-10-31

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