HK1104225A1 - Topical nepafenac formulations - Google Patents
Topical nepafenac formulationsInfo
- Publication number
- HK1104225A1 HK1104225A1 HK07110438.2A HK07110438A HK1104225A1 HK 1104225 A1 HK1104225 A1 HK 1104225A1 HK 07110438 A HK07110438 A HK 07110438A HK 1104225 A1 HK1104225 A1 HK 1104225A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- nepafenac formulations
- topical
- topical nepafenac
- formulations
- nepafenac
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63256204P | 2004-12-02 | 2004-12-02 | |
| PCT/US2005/043545 WO2006060618A2 (en) | 2004-12-02 | 2005-12-02 | Topical nepafenac formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1104225A1 true HK1104225A1 (en) | 2008-01-11 |
Family
ID=35848959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK07110438.2A HK1104225A1 (en) | 2004-12-02 | 2007-09-25 | Topical nepafenac formulations |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US7834059B2 (en) |
| EP (1) | EP1819362B1 (en) |
| JP (2) | JP4968844B2 (en) |
| KR (1) | KR101289661B1 (en) |
| CN (1) | CN101068573A (en) |
| AR (1) | AR052252A1 (en) |
| AT (1) | ATE476200T1 (en) |
| AU (1) | AU2005311738B2 (en) |
| BR (1) | BRPI0518904B1 (en) |
| CA (1) | CA2586807C (en) |
| CY (1) | CY1110780T1 (en) |
| DE (1) | DE602005022756D1 (en) |
| DK (1) | DK1819362T3 (en) |
| ES (1) | ES2348249T3 (en) |
| HK (1) | HK1104225A1 (en) |
| MX (1) | MX2007006558A (en) |
| PL (1) | PL1819362T3 (en) |
| PT (1) | PT1819362E (en) |
| RU (1) | RU2007124638A (en) |
| SI (1) | SI1819362T1 (en) |
| TW (1) | TWI358290B (en) |
| UY (1) | UY29238A1 (en) |
| WO (1) | WO2006060618A2 (en) |
| ZA (1) | ZA200704763B (en) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI358290B (en) | 2004-12-02 | 2012-02-21 | Alcon Inc | Topical nepafenac formulations |
| CA2607014A1 (en) * | 2005-05-10 | 2006-11-16 | Alcon, Inc. | Suspension formulations of nepafenac and other ophthalmic drugs for topical treatment of ophthalmic disorders |
| PL1885336T3 (en) * | 2005-05-10 | 2009-08-31 | Alcon Inc | Suspension formulations comprising an active principle, a poloxamer or meroxapol surfactant and a glycol, its use for the manufacture of a medicament for treating ophthalmic disorders |
| TW200812575A (en) * | 2006-04-28 | 2008-03-16 | Alcon Inc | Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye |
| US20080057022A1 (en) * | 2006-08-30 | 2008-03-06 | Erning Xia | Ophthalmic Pharmaceutical Compositions and Uses Thereof |
| EP2160182A1 (en) * | 2007-05-24 | 2010-03-10 | Aciex Therapeutics, Inc. | Formulations and methods for treating dry eye |
| TWI531362B (en) * | 2008-07-21 | 2016-05-01 | 艾爾康股份有限公司 | Ophthalmic device having therapeutic agent delivery capability |
| TW201023912A (en) | 2008-12-05 | 2010-07-01 | Alcon Res Ltd | Pharmaceutical suspension |
| WO2010101989A1 (en) * | 2009-03-03 | 2010-09-10 | Alcon Research, Ltd. | PHARMACEUTICAL COMPOSITION FOR DELIVERY OF RECEPTOR TYROSINE KINASE INHIBITING (RTKi) COMPOUNDS TO THE EYE |
| WO2010101971A1 (en) * | 2009-03-03 | 2010-09-10 | Alcon Research, Ltd. | Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (rtki) compounds to the eye |
| US8921337B2 (en) | 2009-12-03 | 2014-12-30 | Alcon Research, Ltd. | Carboxyvinyl polymer-containing nanoparticle suspensions |
| US9544143B2 (en) | 2010-03-03 | 2017-01-10 | Duo Security, Inc. | System and method of notifying mobile devices to complete transactions |
| US9532222B2 (en) | 2010-03-03 | 2016-12-27 | Duo Security, Inc. | System and method of notifying mobile devices to complete transactions after additional agent verification |
| US9467463B2 (en) | 2011-09-02 | 2016-10-11 | Duo Security, Inc. | System and method for assessing vulnerability of a mobile device |
| RU2014129268A (en) * | 2011-12-16 | 2016-02-10 | Аллерган, Инк. | OPHTHALMIC COMPOSITIONS THAT CONTAIN GRAVITY POLYVINYL POLYVINYL PROCALT-POLYVINYL ACETATE-POLYETHYLENE Glycol copolymers |
| EP3013790A1 (en) | 2013-06-27 | 2016-05-04 | Mylan Laboratories Ltd. | Process for the preparation of nepafenac |
| CN104490861A (en) * | 2014-11-21 | 2015-04-08 | 三明欣茂药业有限公司 | Sustained-release nepafenac eye-drops preparation |
| EP3721868B1 (en) | 2015-01-26 | 2022-06-01 | Bausch & Lomb Incorporated | Ophthalmic suspension composition |
| ES2758755T3 (en) | 2015-06-01 | 2020-05-06 | Duo Security Inc | Method of applying endpoint health standards |
| CN107024550A (en) * | 2016-12-21 | 2017-08-08 | 广州仁恒医药科技股份有限公司 | The quality control method of nepafenac medical composite for eye |
| CN106963730A (en) * | 2016-12-22 | 2017-07-21 | 广州仁恒医药科技股份有限公司 | Highly stable nepafenac medical composite for eye |
| US10412113B2 (en) | 2017-12-08 | 2019-09-10 | Duo Security, Inc. | Systems and methods for intelligently configuring computer security |
| US11658962B2 (en) | 2018-12-07 | 2023-05-23 | Cisco Technology, Inc. | Systems and methods of push-based verification of a transaction |
| JP6994061B2 (en) * | 2019-02-15 | 2022-01-14 | ノバルティス アーゲー | Preparation of 4- (7-hydroxy-2-isopropyl-4-oxo-4H-quinazoline-3-yl) -benzonitrile |
| CN114272207B (en) * | 2022-01-21 | 2023-04-11 | 山东诺明康药物研究院有限公司 | Nanocrystal suspension eye drops and preparation method thereof |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1226344A (en) | 1967-07-31 | 1971-03-24 | ||
| SE400966B (en) | 1975-08-13 | 1978-04-17 | Robins Co Inc A H | PROCEDURE FOR PREPARING 2-AMINO-3- (OR 5-) BENZOYL-PHENYLETIC ACIDS |
| US4313949A (en) | 1979-09-26 | 1982-02-02 | A. H. Robins Company, Inc. | Method of producing an inhibitory effect on blood platelet aggregation |
| US4254146A (en) | 1979-10-18 | 1981-03-03 | A. H. Robins Company, Inc. | 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and esters |
| IL61945A (en) | 1980-02-19 | 1984-09-30 | Robins Co Inc A H | 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them |
| US4503073A (en) | 1981-01-07 | 1985-03-05 | A. H. Robins Company, Incorporated | 2-Amino-3-(alkylthiobenzoyl)-phenylacetic acids |
| IL64724A0 (en) | 1981-02-17 | 1982-03-31 | Robins Co Inc A H | 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them |
| US4568695A (en) | 1983-12-07 | 1986-02-04 | A. H. Robins Company, Incorporated | 2-Amino-3-benzoyl-phenethylalcohols and intermediates therefor |
| US4851443A (en) | 1985-03-14 | 1989-07-25 | Smith Kline Dauelsberg, Gmbh | Carboxylic acid amides, compositions and medical use thereof |
| EP0195582B1 (en) | 1985-03-14 | 1990-01-24 | SMITH KLINE DAUELSBERG GmbH | 5-aminosalicylic acid derivatives of non-steroidal antiinflammatory acids |
| US4683242A (en) | 1985-10-28 | 1987-07-28 | A. H. Robins Company, Incorporated | Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters |
| DK406686D0 (en) | 1986-08-26 | 1986-08-26 | Hans Bundgaard | carboxylic acid derivatives |
| US4910225A (en) | 1988-01-27 | 1990-03-20 | Senju Pharmaceutical Co., Ltd. | Locally administrable therapeutic composition for inflammatory disease |
| US5461081A (en) | 1989-09-28 | 1995-10-24 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
| US5521222A (en) | 1989-09-28 | 1996-05-28 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
| US5624893A (en) | 1993-10-14 | 1997-04-29 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation |
| US5475034A (en) | 1994-06-06 | 1995-12-12 | Alcon Laboratories, Inc. | Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders |
| US6066671A (en) * | 1997-12-19 | 2000-05-23 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides |
| AR030346A1 (en) * | 2000-08-14 | 2003-08-20 | Alcon Inc | METHOD OF TREATMENT OF NEURODEGENERATIVE DISORDERS OF THE RETINA AND HEAD OF OPTICAL NERVE |
| AR030345A1 (en) * | 2000-08-14 | 2003-08-20 | Alcon Inc | METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS |
| JP2005525408A (en) * | 2002-05-03 | 2005-08-25 | アルコン，インコーポレイテッド | Method for treating vascular endothelial growth factor-mediated vascular injury using amfenac or nepafenac |
| CN100341498C (en) | 2003-01-21 | 2007-10-10 | 千寿制药株式会社 | Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid |
| TWI358290B (en) | 2004-12-02 | 2012-02-21 | Alcon Inc | Topical nepafenac formulations |
-
2005
- 2005-11-23 TW TW094141182A patent/TWI358290B/en active
- 2005-11-28 AR ARP050104964A patent/AR052252A1/en not_active Application Discontinuation
- 2005-11-29 UY UY29238A patent/UY29238A1/en not_active Application Discontinuation
- 2005-12-02 DE DE602005022756T patent/DE602005022756D1/en active Active
- 2005-12-02 MX MX2007006558A patent/MX2007006558A/en active IP Right Grant
- 2005-12-02 ZA ZA200704763A patent/ZA200704763B/en unknown
- 2005-12-02 RU RU2007124638/15A patent/RU2007124638A/en unknown
- 2005-12-02 DK DK05825662.9T patent/DK1819362T3/en active
- 2005-12-02 SI SI200531107T patent/SI1819362T1/en unknown
- 2005-12-02 PL PL05825662T patent/PL1819362T3/en unknown
- 2005-12-02 KR KR1020077012413A patent/KR101289661B1/en active IP Right Review Request
- 2005-12-02 PT PT05825662T patent/PT1819362E/en unknown
- 2005-12-02 CA CA2586807A patent/CA2586807C/en active Active
- 2005-12-02 US US11/292,484 patent/US7834059B2/en active Active
- 2005-12-02 CN CNA200580041442XA patent/CN101068573A/en active Pending
- 2005-12-02 ES ES05825662T patent/ES2348249T3/en active Active
- 2005-12-02 AT AT05825662T patent/ATE476200T1/en active
- 2005-12-02 BR BRPI0518904-7A patent/BRPI0518904B1/en active IP Right Grant
- 2005-12-02 WO PCT/US2005/043545 patent/WO2006060618A2/en active Application Filing
- 2005-12-02 EP EP05825662A patent/EP1819362B1/en active Active
- 2005-12-02 AU AU2005311738A patent/AU2005311738B2/en active Active
- 2005-12-02 JP JP2007544521A patent/JP4968844B2/en active Active
-
2007
- 2007-09-25 HK HK07110438.2A patent/HK1104225A1/en unknown
-
2010
- 2010-09-14 CY CY20101100830T patent/CY1110780T1/en unknown
- 2010-09-23 US US12/888,631 patent/US8071648B2/en active Active
-
2011
- 2011-10-05 US US13/253,648 patent/US8324281B2/en active Active
- 2011-11-25 JP JP2011257966A patent/JP2012041368A/en not_active Withdrawn
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