GR1006568B - Method and system for recording of, and aiding in, the regeneration of a peripheral nerve. - Google Patents

Method and system for recording of, and aiding in, the regeneration of a peripheral nerve.

Info

Publication number
GR1006568B
GR1006568B GR20080100282A GR20080100282A GR1006568B GR 1006568 B GR1006568 B GR 1006568B GR 20080100282 A GR20080100282 A GR 20080100282A GR 20080100282 A GR20080100282 A GR 20080100282A GR 1006568 B GR1006568 B GR 1006568B
Authority
GR
Greece
Prior art keywords
regeneration
nerve
recording
electronic unit
aiding
Prior art date
Application number
GR20080100282A
Other languages
Greek (el)
Inventor
Αλεξανδρος Μπερης
Original Assignee
Αλεξανδρος Μπερης
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Αλεξανδρος Μπερης filed Critical Αλεξανδρος Μπερης
Priority to GR20080100282A priority Critical patent/GR1006568B/en
Priority to PCT/GR2009/000024 priority patent/WO2009130515A2/en
Priority to EP09734126A priority patent/EP2307090A2/en
Publication of GR1006568B publication Critical patent/GR1006568B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Electrotherapy Devices (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Prostheses (AREA)

Abstract

Method and system for the recording of, and aiding in, the regeneration of peripheral nerves after injury, which comprise a stimulation electrode which can be implanted in the central part of the nerve, at least one recording electrode which can beimplanted in the peripheral part of the nerve, an implantable electronic unit, an implantable device that releases regeneration-stimulating agents, such as a micro-pump, and a computational unit which is preferably positioned extra-corporeally for the transmission of data and energy to the electronic unit. The electric signals produced by the peripheral part of the injured nerve, after suitable electric stimulation of the central part thereof, are recorded on various time moments. The analysis of the recorded electric signals is used for the evaluation of the state and progress of the axons under regeneration, from which evaluation various control parameters are determined. The said parameters are used by the electronic unit in order to adjust the release of the stimulating agents so that the therapy is effective, maintaining at the same time the administration of agents at safe levels.
GR20080100282A 2008-04-22 2008-04-22 Method and system for recording of, and aiding in, the regeneration of a peripheral nerve. GR1006568B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GR20080100282A GR1006568B (en) 2008-04-22 2008-04-22 Method and system for recording of, and aiding in, the regeneration of a peripheral nerve.
PCT/GR2009/000024 WO2009130515A2 (en) 2008-04-22 2009-04-15 Method and system for recording and promoting peripheral nerve regeneration
EP09734126A EP2307090A2 (en) 2008-04-22 2009-04-15 Method and system for recording and promoting peripheral nerve regeneration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20080100282A GR1006568B (en) 2008-04-22 2008-04-22 Method and system for recording of, and aiding in, the regeneration of a peripheral nerve.

Publications (1)

Publication Number Publication Date
GR1006568B true GR1006568B (en) 2009-10-13

Family

ID=40585045

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20080100282A GR1006568B (en) 2008-04-22 2008-04-22 Method and system for recording of, and aiding in, the regeneration of a peripheral nerve.

Country Status (3)

Country Link
EP (1) EP2307090A2 (en)
GR (1) GR1006568B (en)
WO (1) WO2009130515A2 (en)

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US9974455B2 (en) 2011-05-13 2018-05-22 Saluda Medical Pty Ltd. Method and apparatus for estimating neural recruitment
US9872990B2 (en) 2011-05-13 2018-01-23 Saluda Medical Pty Limited Method and apparatus for application of a neural stimulus
CA2835486C (en) 2011-05-13 2022-07-19 Saluda Medical Pty Limited Method and apparatus for measurement of neural response - a
WO2012155190A1 (en) * 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for measurement of neural response
EP3357533B1 (en) 2011-05-13 2021-08-11 Saluda Medical Pty Ltd Apparatus for controlling a neural stimulus
AU2012255675B2 (en) 2011-05-13 2016-12-01 Saluda Medical Pty Limited Method and apparatus for application of a neural stimulus - i
US10568559B2 (en) 2011-05-13 2020-02-25 Saluda Medical Pty Ltd Method and apparatus for measurement of neural response
DK2908904T3 (en) 2012-11-06 2020-12-14 Saluda Medical Pty Ltd SYSTEM FOR CONTROLING THE ELECTRICAL CONDITION OF TISSUE
EP3068296A4 (en) 2013-11-15 2017-07-19 Saluda Medical Pty Limited Monitoring brain neural potentials
EP3071100B1 (en) 2013-11-22 2024-01-03 Saluda Medical Pty Limited Method and device for detecting a neural response in a neural measurement
WO2015168735A1 (en) 2014-05-05 2015-11-12 Saluda Medical Pty Ltd Improved neural measurement
ES2873255T3 (en) 2014-07-25 2021-11-03 Saluda Medical Pty Ltd Neurological stimulation dosage
US10597636B2 (en) 2014-09-19 2020-03-24 University Of Florida Research Foundation, Inc. Electroactive polymeric scaffolds and method for delivering nerve growth factor to nerve tissue
WO2016077882A1 (en) 2014-11-17 2016-05-26 Saluda Medical Pty Ltd Method and device for detecting a neural response in neural measurements
WO2016090436A1 (en) 2014-12-11 2016-06-16 Saluda Medical Pty Ltd Method and device for feedback control of neural stimulation
US10588698B2 (en) 2014-12-11 2020-03-17 Saluda Medical Pty Ltd Implantable electrode positioning
EP3229893B1 (en) 2015-01-19 2020-06-17 Saluda Medical Pty Ltd Method and device for neural implant communication
WO2016161484A2 (en) 2015-04-09 2016-10-13 Saluda Medical Pty Ltd Electrode to nerve distance estimation
WO2016191808A1 (en) 2015-05-31 2016-12-08 Saluda Medical Pty Ltd Monitoring brain neural activity
CA2983333C (en) 2015-05-31 2023-09-19 Saluda Medical Pty Ltd Brain neurostimulator electrode fitting
CN107613861B (en) 2015-06-01 2021-10-26 闭环医疗私人有限公司 Motor fiber neuromodulation
CA3019701A1 (en) 2016-04-05 2017-10-12 Saluda Medical Pty Ltd Improved feedback control of neuromodulation
JP7278076B2 (en) 2016-06-24 2023-05-19 サルーダ・メディカル・ピーティーワイ・リミテッド Nerve stimulation to reduce artifacts
WO2018232145A1 (en) * 2017-06-14 2018-12-20 Wichita State University Apparatus and method for neural regeneration
US10589089B2 (en) 2017-10-25 2020-03-17 Epineuron Technologies Inc. Systems and methods for delivering neuroregenerative therapy
CN111511435A (en) 2017-10-25 2020-08-07 艾品诺龙科技公司 Systems and methods for delivering neuroregenerative therapy
JP2021521985A (en) 2018-04-27 2021-08-30 サルーダ・メディカル・ピーティーワイ・リミテッド Nerve stimulation of mixed nerves
US11364381B2 (en) 2019-10-01 2022-06-21 Epineuron Technologies Inc. Methods for delivering neuroregenerative therapy and reducing post-operative and chronic pain

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060089751A1 (en) * 1997-01-27 2006-04-27 Ewa Herbst Electronic delivery systems and methods with feedback
US20060194724A1 (en) * 2005-02-25 2006-08-31 Whitehurst Todd K Methods and systems for nerve regeneration
WO2006108262A2 (en) * 2005-04-15 2006-10-19 Lozano Andres M Regulation of neurotrophins
WO2008005843A2 (en) * 2006-06-30 2008-01-10 Cyberkinetics Neurotechnology Systems, Inc. Nerve regeneration system and lead devices associated therewith

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060089751A1 (en) * 1997-01-27 2006-04-27 Ewa Herbst Electronic delivery systems and methods with feedback
US20060194724A1 (en) * 2005-02-25 2006-08-31 Whitehurst Todd K Methods and systems for nerve regeneration
WO2006108262A2 (en) * 2005-04-15 2006-10-19 Lozano Andres M Regulation of neurotrophins
WO2008005843A2 (en) * 2006-06-30 2008-01-10 Cyberkinetics Neurotechnology Systems, Inc. Nerve regeneration system and lead devices associated therewith

Also Published As

Publication number Publication date
WO2009130515A2 (en) 2009-10-29
WO2009130515A3 (en) 2010-04-01
EP2307090A2 (en) 2011-04-13

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Legal Events

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PG Patent granted
ML Lapse due to non-payment of fees

Effective date: 20131104