GB9511935D0 - Novel compound - Google Patents

Novel compound

Info

Publication number
GB9511935D0
GB9511935D0 GBGB9511935.0A GB9511935A GB9511935D0 GB 9511935 D0 GB9511935 D0 GB 9511935D0 GB 9511935 A GB9511935 A GB 9511935A GB 9511935 D0 GB9511935 D0 GB 9511935D0
Authority
GB
United Kingdom
Prior art keywords
novel compound
novel
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GBGB9511935.0A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Priority to GBGB9511935.0A priority Critical patent/GB9511935D0/en
Publication of GB9511935D0 publication Critical patent/GB9511935D0/en
Priority to AU60110/96A priority patent/AU6011096A/en
Priority to PCT/GB1996/001388 priority patent/WO1997000319A2/en
Priority to CA002224646A priority patent/CA2224646A1/en
Priority to JP9502784A priority patent/JPH11507547A/en
Priority to EP96917584A priority patent/EP0832219A2/en
Priority to US09/859,361 priority patent/US20020058311A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GBGB9511935.0A 1995-06-13 1995-06-13 Novel compound Pending GB9511935D0 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
GBGB9511935.0A GB9511935D0 (en) 1995-06-13 1995-06-13 Novel compound
AU60110/96A AU6011096A (en) 1995-06-13 1996-06-11 Chimeric leptin fused to immunoglobulin domain and use
PCT/GB1996/001388 WO1997000319A2 (en) 1995-06-13 1996-06-11 Chimeric leptin fused to immunoglobulin domain and use
CA002224646A CA2224646A1 (en) 1995-06-13 1996-06-11 Chimeric leptin fused to immunoglobulin domain and use
JP9502784A JPH11507547A (en) 1995-06-13 1996-06-11 Chimeric leptin fused with immunoglobulin domain and uses thereof
EP96917584A EP0832219A2 (en) 1995-06-13 1996-06-11 Chimeric leptin fused to immunoglobulin domain and use
US09/859,361 US20020058311A1 (en) 1995-06-13 2001-05-17 Chimeric leptin fused to immunoglobulin domain and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9511935.0A GB9511935D0 (en) 1995-06-13 1995-06-13 Novel compound

Publications (1)

Publication Number Publication Date
GB9511935D0 true GB9511935D0 (en) 1995-08-09

Family

ID=10775951

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9511935.0A Pending GB9511935D0 (en) 1995-06-13 1995-06-13 Novel compound

Country Status (6)

Country Link
EP (1) EP0832219A2 (en)
JP (1) JPH11507547A (en)
AU (1) AU6011096A (en)
CA (1) CA2224646A1 (en)
GB (1) GB9511935D0 (en)
WO (1) WO1997000319A2 (en)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6310034B1 (en) 1993-05-21 2001-10-30 Ut-Battelle, Llc Agouti polypeptide compositions
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US6429290B1 (en) 1994-08-17 2002-08-06 The Rockefeller University OB polypeptides, modified forms and derivatives
US6936439B2 (en) 1995-11-22 2005-08-30 Amgen Inc. OB fusion protein compositions and methods
US20030040467A1 (en) 1998-06-15 2003-02-27 Mary Ann Pelleymounter Ig/ob fusions and uses thereof.
PT866720E (en) * 1995-11-22 2004-06-30 Amgen Inc PROTEIN OB TO INCREASE MASS OF MOLE TISSUE
AU769250B2 (en) * 1995-12-27 2004-01-22 Genentech Inc. OB protein derivatives having prolonged half-life
US6620413B1 (en) 1995-12-27 2003-09-16 Genentech, Inc. OB protein-polymer chimeras
CN1154726C (en) * 1995-12-27 2004-06-23 基因技术股份有限公司 OB protein derivatives having prolonged half-life
US6541604B1 (en) 1996-01-08 2003-04-01 Genentech, Inc. Leptin receptor having a WSX motif
US7074397B1 (en) 1996-01-08 2006-07-11 Genentech, Inc. Method for enhancing proliferation or differentiation of a cell using ob protein
US20050019325A1 (en) 1996-01-08 2005-01-27 Carter Paul J. WSX receptor agonist antibodies
AU770897B2 (en) * 1996-12-20 2004-03-04 Amgen, Inc. OB fusion protein compositions and methods
JP4175668B2 (en) * 1996-12-20 2008-11-05 アムジエン・インコーポレーテツド OB fusion protein compositions and methods
AU6656098A (en) * 1997-02-25 1998-09-09 Eli Lilly And Company Treatment of infertility with leptin receptor ligands
AU2002300605B8 (en) * 1997-04-17 2006-02-09 Amgen Inc. Compositions Comprising Conjugates of Stable, Active, Human OB Protein with Antibody FC Chain and Methods
US20020019352A1 (en) * 1997-04-17 2002-02-14 David N. Brems Stable, active, human ob protein compositions and methods
DE69807679T2 (en) * 1997-04-17 2003-07-31 Amgen Inc COMPOSITIONS OF CONJUGATES OF THE STABLE, ACTIVE, HUMAN OB PROTEINS WITH THE FC CHAIN OF IMMUNOGLOBULINES AND RELATED PROCEDURES
US6187564B1 (en) 1997-07-10 2001-02-13 Beth Israel Deaconess Medical Center DNA encoding erythropoietin multimers having modified 5′ and 3′ sequences and its use to prepare EPO therapeutics
WO1999002709A1 (en) * 1997-07-10 1999-01-21 Beth Israel Deaconess Medical Center Recombinant erythropoietin / immunoglobulin fusion proteins
US6165476A (en) * 1997-07-10 2000-12-26 Beth Israel Deaconess Medical Center Fusion proteins with an immunoglobulin hinge region linker
US6242570B1 (en) 1997-07-10 2001-06-05 Beth Israel Deaconess Medical Center Production and use of recombinant protein multimers with increased biological activity
PL199659B1 (en) * 1998-02-25 2008-10-31 Merck Patent Gmbh Antibody-based fusion protein featured by prolonged residence in a cireculatory system and method of prolonging its residence time in a circulatory system
EP1101112B1 (en) 1998-07-28 2004-10-06 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Leptin-mediated gene-induction
SK9432001A3 (en) * 1999-01-07 2003-02-04 Lexigen Pharm Corp Expression and export of anti-obesity proteins as Fc fusion proteins
WO2000068376A1 (en) * 1999-05-07 2000-11-16 Genentech, Inc. Novel chimpanzee erythropoietin (chepo) polypeptides and nucleic acids encoding the same
AU7699900A (en) * 1999-10-01 2001-05-10 Eli Lilly And Company A novel human leptin homolog
ES2269366T3 (en) * 2000-02-11 2007-04-01 Merck Patent Gmbh IMPROVEMENT OF AVERAGE LIFE IN CIRCULATION OF FUSION PROTEINS BASED ON ANTIBODIES.
AU8178401A (en) 2000-05-22 2001-12-03 Vlaams Interuniv Inst Biotech Receptor-based interaction trap
US7235629B2 (en) 2000-11-14 2007-06-26 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Functional fragment of the leptin receptor
HUP0303171A2 (en) * 2001-02-19 2003-12-29 Merck Patent Gmbh Artificial proteins with reduced immunogenicity
WO2002079415A2 (en) 2001-03-30 2002-10-10 Lexigen Pharmaceuticals Corp. Reducing the immunogenicity of fusion proteins
NZ543292A (en) 2003-06-12 2008-04-30 Lilly Co Eli GLP-1 analog fusion proteins
CA2526169A1 (en) * 2003-06-12 2004-12-23 Eli Lilly And Company Fusion proteins
WO2005037867A1 (en) 2003-10-15 2005-04-28 Pdl Biopharma, Inc. ALTERATION OF Fc-FUSION PROTEIN SERUM HALF-LIVES BY MUTAGENESIS OF POSITIONS 250, 314 AND/OR 428 OF THE HEAVY CHAIN CONSTANT REGION OF IG
US8110665B2 (en) 2003-11-13 2012-02-07 Hanmi Holdings Co., Ltd. Pharmaceutical composition comprising an immunoglobulin FC region as a carrier
US8846874B2 (en) 2003-11-13 2014-09-30 Hanmi Science Co., Ltd IgG Fc fragment for a drug carrier and method for the preparation thereof
US8420087B2 (en) 2004-01-05 2013-04-16 Antisoma Research Limited Interleukin-12 targeted to oncofoetal fibronectin
US7423113B2 (en) 2004-08-25 2008-09-09 Vib Vzw Leptin antagonist
CA2585549A1 (en) 2004-11-18 2006-05-26 Vib Vzw Novel type leptin receptor antagonist
PT1831252E (en) * 2004-12-22 2009-09-17 Lilly Co Eli Glp-1 analog fusion protein formulations
EP2441838A3 (en) * 2006-01-24 2013-07-10 Domantis Limited Fusion proteins that contain natural junctions
EP2421896A1 (en) 2009-04-22 2012-02-29 Merck Patent GmbH Antibody fusion proteins with modified fcrn binding sites

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59109032D1 (en) * 1990-06-28 1998-09-03 Hoechst Ag Fusion proteins with immunoglobulin components, their production and use
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
GB9509164D0 (en) * 1995-05-05 1995-06-28 Smithkline Beecham Plc Novel compounds
AU5737696A (en) * 1995-05-08 1996-11-29 Chiron Corporation Nucleic acids for treating obesity

Also Published As

Publication number Publication date
EP0832219A2 (en) 1998-04-01
JPH11507547A (en) 1999-07-06
WO1997000319A3 (en) 1997-04-10
WO1997000319A2 (en) 1997-01-03
CA2224646A1 (en) 1997-01-03
AU6011096A (en) 1997-01-15

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