GB8320521D0 - Chemical process - Google Patents

Chemical process

Info

Publication number
GB8320521D0
GB8320521D0 GB838320521A GB8320521A GB8320521D0 GB 8320521 D0 GB8320521 D0 GB 8320521D0 GB 838320521 A GB838320521 A GB 838320521A GB 8320521 A GB8320521 A GB 8320521A GB 8320521 D0 GB8320521 D0 GB 8320521D0
Authority
GB
United Kingdom
Prior art keywords
chemical process
chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB838320521A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to GB838320521A priority Critical patent/GB8320521D0/en
Publication of GB8320521D0 publication Critical patent/GB8320521D0/en
Priority to FI843011A priority patent/FI76808C/en
Priority to SE8403897A priority patent/SE463263B/en
Priority to NO843055A priority patent/NO167292C/en
Priority to IE1938/84A priority patent/IE57726B1/en
Priority to JP59155694A priority patent/JPH0613526B2/en
Priority to CH3672/84A priority patent/CH662121A5/en
Priority to NL8402372A priority patent/NL8402372A/en
Priority to FR8412011A priority patent/FR2549837B1/en
Priority to DE19843427828 priority patent/DE3427828A1/en
Priority to AU31256/84A priority patent/AU582121B2/en
Priority to CA000459929A priority patent/CA1265511A/en
Priority to ZA845830A priority patent/ZA845830B/en
Priority to AT2444/84A priority patent/AT392470B/en
Priority to KR1019840004465A priority patent/KR910008377B1/en
Priority to ES534695A priority patent/ES534695A0/en
Priority to DK366684A priority patent/DK165505C/en
Priority to BE0/213398A priority patent/BE900241A/en
Priority to GB08419202A priority patent/GB2145409B/en
Priority to PT78985A priority patent/PT78985B/en
Priority to IL72536A priority patent/IL72536A/en
Priority to NZ209046A priority patent/NZ209046A/en
Priority to AU36601/89A priority patent/AU634965B2/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
GB838320521A 1983-07-29 1983-07-29 Chemical process Pending GB8320521D0 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
GB838320521A GB8320521D0 (en) 1983-07-29 1983-07-29 Chemical process
PT78985A PT78985B (en) 1983-07-29 1984-07-27 Improvements in or relating to cephalosporins
AU31256/84A AU582121B2 (en) 1983-07-29 1984-07-27 Improvements in or relating to cephalosporins
ZA845830A ZA845830B (en) 1983-07-29 1984-07-27 Cephalosporins
NO843055A NO167292C (en) 1983-07-29 1984-07-27 PROCEDURE FOR THE PREPARATION OF CEFUROXIM 1 ACETOXYLYL ESTE.
IE1938/84A IE57726B1 (en) 1983-07-29 1984-07-27 Improvements in or relating to cephalosporins
JP59155694A JPH0613526B2 (en) 1983-07-29 1984-07-27 Method for producing crystalline cefuroxime acetyl
CH3672/84A CH662121A5 (en) 1983-07-29 1984-07-27 METHOD FOR PRODUCING HIGH PURITY CRYSTALLINE CEFUROXIM-1-ACETOXYETHYLESTER.
NL8402372A NL8402372A (en) 1983-07-29 1984-07-27 PROCESS FOR THE PREPARATION OF CEFUROXIM-AXETIL.
FR8412011A FR2549837B1 (en) 1983-07-29 1984-07-27 PROCESS FOR THE PREPARATION OF 1-ACETOXYETHYL ESTER OF CEFUROXIME
DE19843427828 DE3427828A1 (en) 1983-07-29 1984-07-27 CEPHALOSPORINE IMPROVEMENTS
FI843011A FI76808C (en) 1983-07-29 1984-07-27 FOERFARANDE FOER FRAMSTAELLNING AV CEFUROXIM-1-ACETOXIETYLESTER.
CA000459929A CA1265511A (en) 1983-07-29 1984-07-27 Cephalosporins
SE8403897A SE463263B (en) 1983-07-29 1984-07-27 PROCEDURES FOR THE PREPARATION OF CRYSTALLINE CEFUROXIM-1 ACETOXYTHYLESTER
AT2444/84A AT392470B (en) 1983-07-29 1984-07-27 METHOD FOR PRODUCING HIGH PURITY CRYSTALLINE CEFUROXIM ACETOXYETHYLESTER
KR1019840004465A KR910008377B1 (en) 1983-07-29 1984-07-27 Process for preparation of celphaslosporin
ES534695A ES534695A0 (en) 1983-07-29 1984-07-27 A PROCEDURE TO PREPARE VERY PURE CRYSTALLINE CEFUROXYME ESTER 1-ACETOXYETHYLENE
DK366684A DK165505C (en) 1983-07-29 1984-07-27 PROCEDURE FOR THE PREPARATION OF CRYSTALLINIC CEFUROXIMAXETIL AND THIS CONNECTION IN A HIGH FORM
BE0/213398A BE900241A (en) 1983-07-29 1984-07-27 PROCESS FOR THE PREPARATION OF A-ACETOXYETHYL ESTER OF CEFUROXIME.
GB08419202A GB2145409B (en) 1983-07-29 1984-07-27 Crystalline cefuroxime axetil
IL72536A IL72536A (en) 1983-07-29 1984-07-29 Highly pure crystalline cefuroxime 1-acetoxyethyl ester and preparation thereof
NZ209046A NZ209046A (en) 1983-07-29 1984-07-30 Crystalline cefuroxime 1-acetoxyethyl ester of at least 95 percent mass/mass purity
AU36601/89A AU634965B2 (en) 1983-07-29 1989-06-16 Process for obtaining crystalline cefuroxime 1-acetoxyethyl ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838320521A GB8320521D0 (en) 1983-07-29 1983-07-29 Chemical process

Publications (1)

Publication Number Publication Date
GB8320521D0 true GB8320521D0 (en) 1983-09-01

Family

ID=10546505

Family Applications (2)

Application Number Title Priority Date Filing Date
GB838320521A Pending GB8320521D0 (en) 1983-07-29 1983-07-29 Chemical process
GB08419202A Expired GB2145409B (en) 1983-07-29 1984-07-27 Crystalline cefuroxime axetil

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB08419202A Expired GB2145409B (en) 1983-07-29 1984-07-27 Crystalline cefuroxime axetil

Country Status (21)

Country Link
JP (1) JPH0613526B2 (en)
KR (1) KR910008377B1 (en)
AT (1) AT392470B (en)
AU (2) AU582121B2 (en)
BE (1) BE900241A (en)
CA (1) CA1265511A (en)
CH (1) CH662121A5 (en)
DE (1) DE3427828A1 (en)
DK (1) DK165505C (en)
ES (1) ES534695A0 (en)
FI (1) FI76808C (en)
FR (1) FR2549837B1 (en)
GB (2) GB8320521D0 (en)
IE (1) IE57726B1 (en)
IL (1) IL72536A (en)
NL (1) NL8402372A (en)
NO (1) NO167292C (en)
NZ (1) NZ209046A (en)
PT (1) PT78985B (en)
SE (1) SE463263B (en)
ZA (1) ZA845830B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
US5063224A (en) * 1990-07-09 1991-11-05 Eli Lilly And Company R-cefuroxime axetil
IT1277426B1 (en) * 1995-08-03 1997-11-10 Acs Dobfar Spa BIOAVAILABLE CRYSTALLINE FORM OF CEFUROXIMA AXETIL
CN1111537C (en) * 1997-05-15 2003-06-18 第一制糖株式会社 The preparation method of highly pure crystalline form of cefuroxime axetil
KR100228264B1 (en) * 1997-08-02 1999-11-01 김선진 The synthetic method of crystalline cefuroxime axetil
CA2209868C (en) * 1997-08-15 2001-08-14 Bernard Charles Sherman Pharmaceutical compositions comprising cefuroxime axetil
IN186539B (en) * 1997-09-29 2001-09-29 Ranbaxy Lab Ltd
DK0937727T3 (en) * 1998-02-20 2002-05-13 Fako Ilaclari A S Process for the preparation of soluble crystalline cefuroxime axetil
IN190849B (en) 2000-07-17 2003-08-23 Ranbaxy Lab Ltd
AT411996B (en) 2000-09-11 2004-08-26 Sandoz Ag METHOD FOR PRODUCING CEFUROXIME IN THE FORM OF ITS N-BUTYL LAMONIUM SALTS
ITMI20011763A1 (en) * 2001-08-10 2003-02-10 Antibioticos Spa HIGH-PURITY CEFUROXIME AXELITE PREPARATION PROCESS
ITMI20011925A1 (en) * 2001-09-14 2003-03-14 Antibioticos Spa METHOD APPLICABLE ON INDUSTRIAL SCALE FOR THE PREPARATION OF CEFUROXIME AXETILE CRISTALLINO
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
CN100448879C (en) * 2004-07-22 2009-01-07 北京化工大学 Method for preparing unformed cefuroxime axetil
DE102005019458A1 (en) * 2005-04-25 2006-10-26 Grünenthal GmbH Composition, useful in the preparation of pellets and the multi-particular-presentation form, comprises cefuroximaxetil and carrageenan of the group of lambda carrageenan, tau carrageenan and kappa carrageenan

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1094545A (en) * 1976-02-16 1981-01-27 Michael Gregson Cephalosporin antibiotics
GB1571683A (en) * 1976-02-16 1980-07-16 Glaxo Operations Ltd Ester derivatives of cefuroxime
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS577485A (en) * 1980-06-13 1982-01-14 Takeda Chem Ind Ltd Cephalosporin
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics

Also Published As

Publication number Publication date
GB8419202D0 (en) 1984-08-30
FI76808B (en) 1988-08-31
AT392470B (en) 1991-04-10
ES8601869A1 (en) 1985-11-01
NO843055L (en) 1985-01-30
NL8402372A (en) 1985-02-18
NO167292B (en) 1991-07-15
CH662121A5 (en) 1987-09-15
FI843011A (en) 1985-01-30
KR850001221A (en) 1985-03-16
BE900241A (en) 1985-01-28
ATA244484A (en) 1990-09-15
GB2145409B (en) 1987-02-18
SE8403897L (en) 1985-01-30
DK165505B (en) 1992-12-07
FI76808C (en) 1988-12-12
IL72536A (en) 1988-01-31
DK366684A (en) 1985-01-30
FI843011A0 (en) 1984-07-27
FR2549837B1 (en) 1986-12-26
AU582121B2 (en) 1989-03-16
AU3125684A (en) 1985-01-31
IE841938L (en) 1985-01-29
JPH0613526B2 (en) 1994-02-23
SE8403897D0 (en) 1984-07-27
JPS6075484A (en) 1985-04-27
NO167292C (en) 1991-10-23
ZA845830B (en) 1986-03-26
GB2145409A (en) 1985-03-27
KR910008377B1 (en) 1991-10-12
NZ209046A (en) 1988-02-29
PT78985B (en) 1986-10-23
PT78985A (en) 1984-08-01
IE57726B1 (en) 1993-03-24
DE3427828A1 (en) 1985-02-14
AU634965B2 (en) 1993-03-11
AU3660189A (en) 1989-10-05
ES534695A0 (en) 1985-11-01
DK165505C (en) 1993-04-19
IL72536A0 (en) 1984-11-30
FR2549837A1 (en) 1985-02-01
CA1265511A (en) 1990-02-06
SE463263B (en) 1990-10-29
DK366684D0 (en) 1984-07-27

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