GB2453407B - Matrix-assisted laser desorption with high ionization yield - Google Patents

Matrix-assisted laser desorption with high ionization yield

Info

Publication number
GB2453407B
GB2453407B GB0813569A GB0813569A GB2453407B GB 2453407 B GB2453407 B GB 2453407B GB 0813569 A GB0813569 A GB 0813569A GB 0813569 A GB0813569 A GB 0813569A GB 2453407 B GB2453407 B GB 2453407B
Authority
GB
United Kingdom
Prior art keywords
matrix
laser desorption
assisted laser
high ionization
ionization yield
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB0813569A
Other versions
GB0813569D0 (en
GB2453407A (en
Inventor
Andreas Haase
Jens Hohndorf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bruker Daltonics GmbH and Co KG
Original Assignee
Bruker Daltonik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102007043456A external-priority patent/DE102007043456B4/en
Application filed by Bruker Daltonik GmbH filed Critical Bruker Daltonik GmbH
Publication of GB0813569D0 publication Critical patent/GB0813569D0/en
Publication of GB2453407A publication Critical patent/GB2453407A/en
Application granted granted Critical
Publication of GB2453407B publication Critical patent/GB2453407B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Landscapes

  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
GB0813569A 2007-07-31 2008-07-24 Matrix-assisted laser desorption with high ionization yield Active GB2453407B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007035826 2007-07-31
DE102007043456A DE102007043456B4 (en) 2007-07-31 2007-09-12 Matrix-assisted laser desorption with high ionization efficiency

Publications (3)

Publication Number Publication Date
GB0813569D0 GB0813569D0 (en) 2008-09-03
GB2453407A GB2453407A (en) 2009-04-08
GB2453407B true GB2453407B (en) 2012-07-18

Family

ID=39746872

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0813569A Active GB2453407B (en) 2007-07-31 2008-07-24 Matrix-assisted laser desorption with high ionization yield

Country Status (1)

Country Link
GB (1) GB2453407B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009013653B4 (en) 2009-03-18 2014-09-18 Bruker Daltonik Gmbh Protein sequencing with MALDI mass spectrometry
GB2556074A (en) 2016-11-17 2018-05-23 Micromass Ltd Axial atmospheric pressure photo-ionization imaging source and inlet device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965884A (en) * 1998-06-04 1999-10-12 The Regents Of The University Of California Atmospheric pressure matrix assisted laser desorption
US20020109085A1 (en) * 1996-09-19 2002-08-15 Franz Hillenkamp Method and apparatus for maldi analysis
US20030222212A1 (en) * 2002-05-31 2003-12-04 Beck Kenneth M. High spatial resolution matrix assisted laser desorption/ionization (maldi)
GB2423187A (en) * 2005-02-10 2006-08-16 Bruker Daltonik Gmbh A method and system for providing a choice of spatial intensity distributions of laser radiation in MALDI mass spectroscopy.
GB2437623A (en) * 2006-04-27 2007-10-31 Bruker Daltonik Gmbh Method and apparatus for sample preparation for imaging mass spectrometry

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020109085A1 (en) * 1996-09-19 2002-08-15 Franz Hillenkamp Method and apparatus for maldi analysis
US5965884A (en) * 1998-06-04 1999-10-12 The Regents Of The University Of California Atmospheric pressure matrix assisted laser desorption
US20030222212A1 (en) * 2002-05-31 2003-12-04 Beck Kenneth M. High spatial resolution matrix assisted laser desorption/ionization (maldi)
GB2423187A (en) * 2005-02-10 2006-08-16 Bruker Daltonik Gmbh A method and system for providing a choice of spatial intensity distributions of laser radiation in MALDI mass spectroscopy.
GB2437623A (en) * 2006-04-27 2007-10-31 Bruker Daltonik Gmbh Method and apparatus for sample preparation for imaging mass spectrometry

Also Published As

Publication number Publication date
GB0813569D0 (en) 2008-09-03
GB2453407A (en) 2009-04-08

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Legal Events

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Free format text: REGISTERED BETWEEN 20210722 AND 20210728