GB2232984B - Method of adsorbing immunoglobulin by using porous beads of chitosan - Google Patents

Method of adsorbing immunoglobulin by using porous beads of chitosan

Info

Publication number
GB2232984B
GB2232984B GB9016548A GB9016548A GB2232984B GB 2232984 B GB2232984 B GB 2232984B GB 9016548 A GB9016548 A GB 9016548A GB 9016548 A GB9016548 A GB 9016548A GB 2232984 B GB2232984 B GB 2232984B
Authority
GB
United Kingdom
Prior art keywords
chitosan
porous beads
immunoglobulin
adsorbing
adsorbing immunoglobulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB9016548A
Other versions
GB9016548D0 (en
GB2232984A (en
Inventor
Soyao Moriguchi
Hiroshi Suzuki
Hiroko Watanabe
Motoaki Satoh
Michio Abe
Yasuo Iwata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SB Kawasumi Laboratories Inc
Resonac Holdings Corp
Original Assignee
Kawasumi Laboratories Inc
Showa Denko KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61192142A external-priority patent/JPS6348452A/en
Priority claimed from JP61192141A external-priority patent/JPS6348451A/en
Priority claimed from JP61192143A external-priority patent/JPS6348453A/en
Priority claimed from JP61192144A external-priority patent/JPS6348222A/en
Priority claimed from JP62033472A external-priority patent/JPS63200770A/en
Priority claimed from GB8719348A external-priority patent/GB2195344B/en
Application filed by Kawasumi Laboratories Inc, Showa Denko KK filed Critical Kawasumi Laboratories Inc
Publication of GB9016548D0 publication Critical patent/GB9016548D0/en
Publication of GB2232984A publication Critical patent/GB2232984A/en
Publication of GB2232984B publication Critical patent/GB2232984B/en
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3285—Coating or impregnation layers comprising different type of functional groups or interactions, e.g. different ligands in various parts of the sorbent, mixed mode, dual zone, bimodal, multimodal, ionic or hydrophobic, cationic or anionic, hydrophilic or hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0415—Plasma
    • A61M2202/0417—Immunoglobulin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
GB9016548A 1986-08-19 1990-07-27 Method of adsorbing immunoglobulin by using porous beads of chitosan Expired - Lifetime GB2232984B (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP61192142A JPS6348452A (en) 1986-08-19 1986-08-19 Adsorption carrier for chromatography
JP61192144A JPS6348222A (en) 1986-08-19 1986-08-19 Adsorbent for factor inhibiting activity of interleukin-2
JP61192143A JPS6348453A (en) 1986-08-19 1986-08-19 Carrier for chromatography and its production
JP61192141A JPS6348451A (en) 1986-08-19 1986-08-19 Adsorption carrier for chromatography
JP62033472A JPS63200770A (en) 1987-02-18 1987-02-18 Immunoglobulin adsorbent
GB8719348A GB2195344B (en) 1986-08-19 1987-08-14 Adsorbent composed of porous beads of chitosan and adsorption method using same

Publications (3)

Publication Number Publication Date
GB9016548D0 GB9016548D0 (en) 1990-09-12
GB2232984A GB2232984A (en) 1991-01-02
GB2232984B true GB2232984B (en) 1991-05-08

Family

ID=27546976

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9016548A Expired - Lifetime GB2232984B (en) 1986-08-19 1990-07-27 Method of adsorbing immunoglobulin by using porous beads of chitosan

Country Status (1)

Country Link
GB (1) GB2232984B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10117043A1 (en) * 2001-04-05 2002-11-07 Gerhard Puetz Process for the elimination of potentially toxic and / or harmful substances
RU2313538C2 (en) * 2005-08-04 2007-12-27 Борис Олегович Майер Chitosan product, method for its preparing (variants)
DE102016004432A1 (en) * 2016-04-12 2017-10-12 Sartorius Stedim Biotech Gmbh Multimodal adsorption medium with multimodal ligands, process for its preparation and its use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6253669A (en) * 1985-08-31 1987-03-09 テルモ株式会社 Material and apparatus for adsorbing immunoglobulin substance

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6253669A (en) * 1985-08-31 1987-03-09 テルモ株式会社 Material and apparatus for adsorbing immunoglobulin substance

Also Published As

Publication number Publication date
GB9016548D0 (en) 1990-09-12
GB2232984A (en) 1991-01-02

Similar Documents

Publication Publication Date Title
GB2195344B (en) Adsorbent composed of porous beads of chitosan and adsorption method using same
DE3464857D1 (en) Process for preparing superficially porous supports for chromatography and catalysts
EP0242544A3 (en) Adsorbent for chromatography, method of producing the same, and column system for chromatography
DE3478809D1 (en) Adsorptive separation process
GB2137938B (en) Method of vehicle construction
GB8328403D0 (en) Chemical purification method
AU565440B2 (en) Reactivation of zeolite catalyst
AU569205B2 (en) Continuous adsorption process
ZA8270B (en) Method of preparation of composite zeolite catalysts
AU566505B2 (en) Enhancing stability of zeolite catalysts
GB2232984B (en) Method of adsorbing immunoglobulin by using porous beads of chitosan
JPS6447388A (en) Chromatographic purification method
AU2508384A (en) Crystaline silica polymorphs and preparation method
BG46338A1 (en) Method for obtaining of hydrophobic adsorbents
GB2142014B (en) Method of purifying 4-fluorophenol
CS222335B1 (en) Method of catalyst reactivation or regeneration
GB2090822B (en) Binderless zeolite extrudates and method of producing same
PL251416A2 (en) Method of modifying porous polymers sorbents for chromatography
ZA874020B (en) Adsorption process
PL241291A2 (en) Method of manufacture of novel chlorosulfonyl,styrene-divinylbenzene sorbents
PL247335A1 (en) Method of purifying microbiological proteinous isolates
JPS57177344A (en) Method of regenerating adsorbent
PL262898A1 (en) Method of regen rating membrane filters
AU8236482A (en) Regeneration of coagulant/adsorbent
JPS5561913A (en) Regeneration method of adsorbent

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960814