GB201516243D0 - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- GB201516243D0 GB201516243D0 GBGB1516243.1A GB201516243A GB201516243D0 GB 201516243 D0 GB201516243 D0 GB 201516243D0 GB 201516243 A GB201516243 A GB 201516243A GB 201516243 D0 GB201516243 D0 GB 201516243D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- novel compounds
- novel
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1516243.1A GB201516243D0 (en) | 2015-09-14 | 2015-09-14 | Novel compounds |
PCT/EP2016/071466 WO2017046036A1 (en) | 2015-09-14 | 2016-09-12 | Compounds for the modulation of rip2 kinase activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1516243.1A GB201516243D0 (en) | 2015-09-14 | 2015-09-14 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB201516243D0 true GB201516243D0 (en) | 2015-10-28 |
Family
ID=54363130
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB1516243.1A Ceased GB201516243D0 (en) | 2015-09-14 | 2015-09-14 | Novel compounds |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB201516243D0 (en) |
WO (1) | WO2017046036A1 (en) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2016232705C1 (en) | 2015-03-18 | 2021-06-17 | Arvinas, Inc. | Compounds and methods for the enhanced degradation of targeted proteins |
GB201506872D0 (en) * | 2015-04-22 | 2015-06-03 | Ge Oil & Gas Uk Ltd | Novel compounds |
EP3445760B1 (en) * | 2016-04-22 | 2022-02-23 | Dana-Farber Cancer Institute, Inc. | Degradation of cyclin-dependent kinase 9 (cdk9) by conjugation of cdk9 inhibitors with e3 ligase ligand and methods of use |
MX2019005007A (en) | 2016-11-01 | 2019-07-18 | Arvinas Inc | Tau-protein targeting protacs and associated methods of use. |
KR102173464B1 (en) | 2016-12-01 | 2020-11-04 | 아비나스 오퍼레이션스, 인코포레이티드 | Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders |
KR102564201B1 (en) | 2016-12-23 | 2023-08-07 | 아비나스 오퍼레이션스, 인코포레이티드 | Compounds and methods for targeted degradation of rapidly progressive fibrosarcoma polypeptides |
EP3559006A4 (en) | 2016-12-23 | 2021-03-03 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of fetal liver kinase polypeptides |
US11173211B2 (en) | 2016-12-23 | 2021-11-16 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of rapidly accelerated Fibrosarcoma polypeptides |
EP3559002A4 (en) | 2016-12-23 | 2021-02-17 | Arvinas Operations, Inc. | Egfr proteolysis targeting chimeric molecules and associated methods of use |
EP3573977A4 (en) | 2017-01-26 | 2020-12-23 | Arvinas Operations, Inc. | Modulators of estrogen receptor proteolysis and associated methods of use |
EP3710002A4 (en) | 2017-11-16 | 2021-07-07 | C4 Therapeutics, Inc. | Degraders and degrons for targeted protein degradation |
EP3710443A1 (en) | 2017-11-17 | 2020-09-23 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of interleukin-1 receptor-associated kinase 4 polypeptides |
CA3095494C (en) | 2018-04-04 | 2023-11-07 | Arvinas Operations, Inc. | Modulators of proteolysis and associated methods of use |
WO2019204354A1 (en) | 2018-04-16 | 2019-10-24 | C4 Therapeutics, Inc. | Spirocyclic compounds |
JP2021527137A (en) * | 2018-06-13 | 2021-10-11 | アンフィスタ セラピューティクス リミテッド | Bifunctional molecule for targeting Rpn11 |
WO2020041331A1 (en) | 2018-08-20 | 2020-02-27 | Arvinas Operations, Inc. | Proteolysis targeting chimeric (protac) compound with e3 ubiquitin ligase binding activity and targeting alpha-synuclein protein for treating neurodegenerative diseases |
WO2020043122A1 (en) * | 2018-08-28 | 2020-03-05 | 南京明德新药研发有限公司 | Quinazoline derivatives as rip2 kinase inhibitor |
BR112021010484A2 (en) * | 2018-11-30 | 2021-08-24 | Kymera Therapeutics, Inc. | Irak degraders and their uses |
EP3891128A4 (en) * | 2018-12-05 | 2022-08-17 | Vividion Therapeutics, Inc. | Substituted isoindolinones as modulators of cereblon-mediated neo-substrate recruitment |
CN113453679A (en) | 2018-12-20 | 2021-09-28 | C4医药公司 | Targeted protein degradation |
WO2020191369A1 (en) | 2019-03-21 | 2020-09-24 | Codiak Biosciences, Inc. | Process for preparing extracellular vesicles |
CN113747925A (en) | 2019-03-21 | 2021-12-03 | 科迪亚克生物科学公司 | Extracellular vesicle conjugates and uses thereof |
US11912699B2 (en) | 2019-07-17 | 2024-02-27 | Arvinas Operations, Inc. | Tau-protein targeting compounds and associated |
CN114728950A (en) | 2019-11-19 | 2022-07-08 | 百时美施贵宝公司 | Compounds useful as inhibitors of HELIOS proteins |
KR20220119094A (en) | 2019-12-19 | 2022-08-26 | 아비나스 오퍼레이션스, 인코포레이티드 | Compounds and methods for targeted degradation of androgen receptors |
CN111499623B (en) * | 2020-04-01 | 2022-07-08 | 南京缘聚医药科技有限公司 | Thiazolone urea derivatives of non-nucleoside antitumor drugs and pharmaceutical application thereof |
WO2021237100A1 (en) | 2020-05-21 | 2021-11-25 | Codiak Biosciences, Inc. | Methods of targeting extracellular vesicles to lung |
WO2022066928A2 (en) | 2020-09-23 | 2022-03-31 | Codiak Biosciences, Inc. | Process for preparing extracellular vesicles |
WO2022120118A1 (en) * | 2020-12-03 | 2022-06-09 | Baylor College Of Medicine | Novel ripk1 kinase targeting protacs and methods of use thereof |
CA3208313A1 (en) | 2021-01-13 | 2022-07-21 | Monte Rosa Therapeutics Ag | Isoindolinone compounds |
PE20231941A1 (en) | 2021-04-06 | 2023-12-05 | Bristol Myers Squibb Co | PYRIDINYL SUBSTITUTED OXOISOINDOLINE COMPOUNDS |
CA3217417A1 (en) | 2021-05-05 | 2022-11-10 | Kevin M. Guckian | Compounds for targeting degradation of bruton's tyrosine kinase |
WO2022266248A1 (en) * | 2021-06-16 | 2022-12-22 | Biotheryx, Inc. | Sos1 protein degraders, pharmaceutical compositions thereof, and their therapeutic applications |
EP4366834A1 (en) | 2021-07-07 | 2024-05-15 | Biogen MA Inc. | Compounds for targeting degradation of irak4 proteins |
IL309941A (en) | 2021-07-07 | 2024-03-01 | Biogen Ma Inc | Compounds for targeting degradation of irak4 proteins |
US11957759B1 (en) | 2022-09-07 | 2024-04-16 | Arvinas Operations, Inc. | Rapidly accelerated fibrosarcoma (RAF) degrading compounds and associated methods of use |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69413955T2 (en) | 1993-03-17 | 1999-04-01 | Minnesota Mining & Mfg | AEROSOL COMPOSITION CONTAINING A DERIVATIVE DERIVATIVE FROM ESTER, AMID OR MERCAPTOESTER |
US6126919A (en) | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
EP1699512B1 (en) | 2003-11-03 | 2012-06-20 | Glaxo Group Limited | A fluid dispensing device |
GB0610666D0 (en) | 2006-05-30 | 2006-07-05 | Glaxo Group Ltd | Fluid dispenser |
ES2552977T3 (en) | 2010-05-07 | 2015-12-03 | Glaxosmithkline Intellectual Property Development Limited | Amino-quinolines as kinase inhibitors |
UY33549A (en) | 2010-08-10 | 2012-01-31 | Glaxo Group Ltd | QUINOLIL AMINAS AS INHIBITING AGENTS OF KINASES |
AU2012225735B2 (en) | 2011-03-04 | 2016-03-10 | Glaxosmithkline Intellectual Property Development Limited | Amino-quinolines as kinase inhibitors |
TWI547494B (en) | 2011-08-18 | 2016-09-01 | 葛蘭素史克智慧財產發展有限公司 | Amino quinazolines as kinase inhibitors |
KR102204989B1 (en) | 2012-01-12 | 2021-01-20 | 예일 유니버시티 | Compounds and Methods for the Enhanced Degradation of Targeted Proteins and Other Polypeptides by an E3 Ubiquitin Ligase |
TW201425307A (en) | 2012-09-13 | 2014-07-01 | Glaxosmithkline Llc | Amino-quinolines as kinase inhibitors |
ES2654100T3 (en) | 2013-02-21 | 2018-02-12 | Glaxosmithkline Intellectual Property Development Limited | Quinazolines as kinase inhibitors |
-
2015
- 2015-09-14 GB GBGB1516243.1A patent/GB201516243D0/en not_active Ceased
-
2016
- 2016-09-12 WO PCT/EP2016/071466 patent/WO2017046036A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2017046036A1 (en) | 2017-03-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |