GB2013087A - Sterol liposomes containing medicaments - Google Patents

Sterol liposomes containing medicaments

Info

Publication number
GB2013087A
GB2013087A GB7902881A GB7902881A GB2013087A GB 2013087 A GB2013087 A GB 2013087A GB 7902881 A GB7902881 A GB 7902881A GB 7902881 A GB7902881 A GB 7902881A GB 2013087 A GB2013087 A GB 2013087A
Authority
GB
United Kingdom
Prior art keywords
medicament
beta
liposomes containing
sterol
cholesterol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7902881A
Other versions
GB2013087B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB2013087A publication Critical patent/GB2013087A/en
Application granted granted Critical
Publication of GB2013087B publication Critical patent/GB2013087B/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Liposomes formed from liquid crystals of a sterol, for example cholesterol, beta -sitosterol, desmosterol, 7-keto- cholesterol, beta -cholestanol or estradiol, and an aliphatic lipid capable of forming micelles in water, for example sodium or potassium salts of saturated or unsaturated C4-18 fatty acids, encapsulate medicaments (e.g. insulin, mazindol or ergot alkaloids). The medicament-containing liposomes are used by themselves or together with a pharmaceutical carrier or diluent, for oral or parenteral administration of the medicament.
GB7902881A 1978-01-27 1979-01-26 Liposome delivery systems Expired GB2013087B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87283578A 1978-01-27 1978-01-27

Publications (2)

Publication Number Publication Date
GB2013087A true GB2013087A (en) 1979-08-08
GB2013087B GB2013087B (en) 1982-07-21

Family

ID=25360392

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7902881A Expired GB2013087B (en) 1978-01-27 1979-01-26 Liposome delivery systems

Country Status (19)

Country Link
JP (1) JPS54113417A (en)
AT (1) AT368888B (en)
AU (1) AU524529B2 (en)
BE (1) BE873715A (en)
CA (1) CA1111347A (en)
DE (1) DE2902672A1 (en)
DK (1) DK22879A (en)
ES (1) ES477217A1 (en)
FI (1) FI790164A (en)
FR (1) FR2415460A1 (en)
GB (1) GB2013087B (en)
IE (1) IE790144L (en)
IL (1) IL56499A (en)
IT (1) IT1109867B (en)
NL (1) NL7900545A (en)
NZ (1) NZ189477A (en)
PT (1) PT69132A (en)
SE (1) SE7900458L (en)
ZA (1) ZA79349B (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007714A1 (en) * 1978-07-03 1980-02-06 National Research Development Corporation Liposomes and compositions containing them
GB2135878A (en) * 1981-10-29 1984-09-12 Nippon Shinyaku Co Ltd Liposome containing steryl glycoside
US4849227A (en) * 1986-03-21 1989-07-18 Eurasiam Laboratories, Inc. Pharmaceutical compositions
WO1992003123A1 (en) * 1990-08-28 1992-03-05 Liposome Technology, Inc. Liposome alternative bilayer formulations
FR2714621A1 (en) * 1994-01-06 1995-07-07 Centre Nat Rech Scient Process for the preparation of liposomes without the use of an organic solvent
EP1122304A1 (en) * 1999-08-13 2001-08-08 Suntory Limited Microorganism secreting out lipid and process for producing the lipid and lipid balls having the lipid encapsulating therein by using the microorganism
US7863024B2 (en) 2002-04-26 2011-01-04 Suntory Holdings Limited Process for producing highly unsaturated fatty acid-containing lipid
WO2013026989A3 (en) * 2011-08-25 2013-08-08 Trophos Liposome comprising at least one cholesterol derivative
AU2013203682B2 (en) * 2011-08-25 2016-03-31 Trophos Liposome comprising at least one cholesterol derivative

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3374837D1 (en) * 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
EP0102324A3 (en) * 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipids and surfactants in an aqueous medium
DE3421468A1 (en) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim LIPID NANOPELLETS AS A CARRIER SYSTEM FOR MEDICINAL PRODUCTS FOR PERORAL USE
US5077211A (en) * 1988-07-06 1991-12-31 Applied Genetics, Inc. Purification and administration of dna repair enzymes
CN113967192A (en) * 2021-11-09 2022-01-25 陕西海斯夫生物工程有限公司 Pharmaceutical composition for accelerating wound healing, preparation method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957951A (en) * 1974-08-23 1976-05-18 International Telephone And Telegraph Corporation Process for removing contaminants from hot waste gas streams
FR2315991A1 (en) * 1975-06-30 1977-01-28 Oreal METHOD OF MANUFACTURING AQUEOUS DISPERSIONS OF LIPID SPHERULES AND CORRESPONDING NEW COMPOSITIONS
FR2408387A2 (en) * 1975-06-30 1979-06-08 Oreal COMPOSITIONS BASED ON AQUEOUS DISPERSIONS OF LIPID SPHERULES
FR2374910A1 (en) * 1976-10-23 1978-07-21 Choay Sa PREPARATION BASED ON HEPARIN, INCLUDING LIPOSOMES, PROCESS FOR OBTAINING IT AND MEDICINAL PRODUCTS CONTAINING SUCH PREPARATIONS

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007714A1 (en) * 1978-07-03 1980-02-06 National Research Development Corporation Liposomes and compositions containing them
GB2135878A (en) * 1981-10-29 1984-09-12 Nippon Shinyaku Co Ltd Liposome containing steryl glycoside
US4849227A (en) * 1986-03-21 1989-07-18 Eurasiam Laboratories, Inc. Pharmaceutical compositions
WO1992003123A1 (en) * 1990-08-28 1992-03-05 Liposome Technology, Inc. Liposome alternative bilayer formulations
FR2714621A1 (en) * 1994-01-06 1995-07-07 Centre Nat Rech Scient Process for the preparation of liposomes without the use of an organic solvent
EP1122304A4 (en) * 1999-08-13 2004-03-17 Suntory Ltd Microorganism secreting out lipid and process for producing the lipid and lipid balls having the lipid encapsulating therein by using the microorganism
EP1122304A1 (en) * 1999-08-13 2001-08-08 Suntory Limited Microorganism secreting out lipid and process for producing the lipid and lipid balls having the lipid encapsulating therein by using the microorganism
AU784465B2 (en) * 1999-08-13 2006-04-06 Suntory Holdings Limited Microorganism secreting out lipid and process for producing the lipid and lipid balls having the lipid encapsulating therein by using the microorganism
US7157254B1 (en) 1999-08-13 2007-01-02 Suntory Limited Microorganism secreting out lipid and process for producing the lipid and lipid balls having the lipid encapsulating therein by using the mircroorganism
US7972855B2 (en) 1999-08-13 2011-07-05 Suntory Holdings Limited Microorganisms that extracellularly secrete lipids and methods of producing lipid and lipid vesicles encapsulating lipids using said microorganisms
US9782378B2 (en) 1999-08-13 2017-10-10 Suntory Holdings Limited Microorganisms that extracellularly secrete lipid particles encapsulating lipids
US10201514B2 (en) 1999-08-13 2019-02-12 Suntory Holdings Limited Microorganisms that extracellularly secrete lipids and methods of producing lipid and lipid particles encapsulating lipids using said microorganisms
US7863024B2 (en) 2002-04-26 2011-01-04 Suntory Holdings Limited Process for producing highly unsaturated fatty acid-containing lipid
WO2013026989A3 (en) * 2011-08-25 2013-08-08 Trophos Liposome comprising at least one cholesterol derivative
AU2013203682B2 (en) * 2011-08-25 2016-03-31 Trophos Liposome comprising at least one cholesterol derivative

Also Published As

Publication number Publication date
GB2013087B (en) 1982-07-21
DE2902672A1 (en) 1979-08-02
ES477217A1 (en) 1980-04-01
AU524529B2 (en) 1982-09-23
PT69132A (en) 1979-02-01
NL7900545A (en) 1979-07-31
BE873715A (en) 1979-07-25
ATA58979A (en) 1982-04-15
AT368888B (en) 1982-11-25
IE790144L (en) 1979-07-27
IT7919649A0 (en) 1979-01-26
ZA79349B (en) 1980-09-24
DK22879A (en) 1979-07-28
IT1109867B (en) 1985-12-23
SE7900458L (en) 1979-07-28
FR2415460B1 (en) 1983-05-20
FI790164A (en) 1979-07-28
JPS54113417A (en) 1979-09-05
AU4367879A (en) 1979-08-02
IL56499A (en) 1981-09-13
CA1111347A (en) 1981-10-27
IL56499A0 (en) 1979-03-12
NZ189477A (en) 1981-05-01
FR2415460A1 (en) 1979-08-24

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee