GB1462958A - Biodegradable implantable drug delivery device and process for preparing and using the same - Google Patents

Biodegradable implantable drug delivery device and process for preparing and using the same

Info

Publication number
GB1462958A
GB1462958A GB2136174A GB2136174A GB1462958A GB 1462958 A GB1462958 A GB 1462958A GB 2136174 A GB2136174 A GB 2136174A GB 2136174 A GB2136174 A GB 2136174A GB 1462958 A GB1462958 A GB 1462958A
Authority
GB
United Kingdom
Prior art keywords
implanted
preparing
same
delivery device
drug delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2136174A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arthur D Little Inc
Original Assignee
Arthur D Little Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arthur D Little Inc filed Critical Arthur D Little Inc
Publication of GB1462958A publication Critical patent/GB1462958A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/2045—Polyamides; Polyaminoacids, e.g. polylysine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)

Abstract

1462958 Controlled release devices ARTHUR D LITTLE Inc 14 May 1974 [17 May 1973] 21361/74 Heading A5B An implant device for the controllable release of a biologically active substance or a diagnostic agent into a living host into which it is to be implanted comprises a biodegradable matrix structure formed from a substantially non-toxic polymer of an alpha-amino acid having the substance which is to be controllably released physically distributed therethrough. The implants may be for example, in the form of films, ribbons rods or fibres and may be implanted in or near an organ of the body, or they may be implanted subdermally They may also be administered as uterine or vaginal inserts.
GB2136174A 1973-05-17 1974-05-14 Biodegradable implantable drug delivery device and process for preparing and using the same Expired GB1462958A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36118273A 1973-05-17 1973-05-17

Publications (1)

Publication Number Publication Date
GB1462958A true GB1462958A (en) 1977-01-26

Family

ID=23420985

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2136174A Expired GB1462958A (en) 1973-05-17 1974-05-14 Biodegradable implantable drug delivery device and process for preparing and using the same

Country Status (6)

Country Link
JP (1) JPS5040718A (en)
CA (1) CA1045977A (en)
CH (1) CH591255A5 (en)
DE (1) DE2424169A1 (en)
FR (1) FR2287242A1 (en)
GB (1) GB1462958A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2295316A (en) * 1994-11-25 1996-05-29 William Leslie Porter Bolus for supplying biologically beneficial substances to ruminant animals
US7833548B2 (en) 2002-06-18 2010-11-16 Surmodics, Inc. Bioactive agent release coating and controlled humidity method
US10390702B2 (en) 2011-12-30 2019-08-27 Kibur Medical, Inc. Implantable devices and methods for the evaluation of active agents

Families Citing this family (69)

* Cited by examiner, † Cited by third party
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JPS5423050B2 (en) * 1972-04-28 1979-08-10
JPS4964542A (en) * 1972-10-25 1974-06-22
JPS52137559A (en) * 1976-05-12 1977-11-17 Brother Ind Ltd Coupling method for component parts
DE2856901D2 (en) * 1977-06-07 1980-11-13 Garching Instrumente Form of implant medicament and preparation process
AR221964A1 (en) * 1979-09-12 1981-03-31 Lilly Co Eli DEVICE FOR RUMINANTS
GB2077586A (en) * 1980-06-12 1981-12-23 Standard Telephones Cables Ltd Sustained-release device
JPS57128621A (en) * 1981-01-30 1982-08-10 Japan Atom Energy Res Inst Preparation of prolonged release type composite
JPS58144314A (en) * 1982-02-19 1983-08-27 Japan Atom Energy Res Inst Preparation of combined substance having prolonged effect
JPS58154509A (en) * 1982-03-10 1983-09-14 Japan Atom Energy Res Inst Preparation of slow-releasing composite
JPS58192817A (en) * 1982-05-06 1983-11-10 Nippon Soda Co Ltd Production of stick-like drug preparation
US5248700A (en) * 1982-05-14 1993-09-28 Akzo Nv Active agent containing solid structures for prolonged release of active agents
JPS58213708A (en) * 1982-06-03 1983-12-12 Mitsui Toatsu Chem Inc Preparation of molded bar drug having prolonged effect
JPS58225008A (en) * 1982-06-25 1983-12-27 Japan Atom Energy Res Inst Preparation of prolonged action compounded substance
JPS5968209A (en) * 1982-10-13 1984-04-18 Mikuni Plast Kk Manufacture of joint pipe
JPS59135053A (en) * 1983-01-20 1984-08-03 日本特殊陶業株式会社 Liquid medicine impregnated fibrous ceramics
JPS59139318A (en) * 1983-01-31 1984-08-10 Mitsui Toatsu Chem Inc Production of filmlike or sheetlike molded pharmaceutical material
DE3463211D1 (en) * 1983-07-01 1987-05-21 Battelle Memorial Institute Biodegradable polypeptide and its use in the sustained release of medicaments
GB2146524B (en) * 1983-09-15 1987-04-08 Stc Plc Differential release system for aqueous media
GB2146531B (en) * 1983-09-15 1987-04-29 Stc Plc Controlled release system
JPS60237015A (en) * 1984-05-11 1985-11-25 Koken:Kk Sustained release drug
DE3671375D1 (en) * 1985-02-19 1990-06-28 Dow Chemical Co HARD TISSUE PROSTHESIS AND METHOD FOR THEIR PRODUCTION.
DE3533369A1 (en) * 1985-09-19 1987-03-19 Alois Prof Dr Med Bloemer ANTIBIOTIC CONTAINER AND ITS USE AS SURGICAL PLASTIC MATERIAL
CH667874A5 (en) * 1985-12-19 1988-11-15 Battelle Memorial Institute BIODEGRADABLE SYNTHETIC POLYPEPTIDE AND ITS USE FOR THE PREPARATION OF MEDICAMENTS.
JPS62247554A (en) * 1986-04-18 1987-10-28 Ibiden Co Ltd Pin grid array package substrate
JPS62247555A (en) * 1986-04-18 1987-10-28 Ibiden Co Ltd Pin grid array package substrate
EP0318512B1 (en) * 1986-08-18 1998-06-17 Emisphere Technologies, Inc. Delivery systems for pharmacological agents
DE3745075C2 (en) * 1986-08-18 1997-04-30 Emisphere Tech Inc Therapeutic agent encapsulated in proteinoid microspheres
USRE35862E (en) * 1986-08-18 1998-07-28 Emisphere Technologies, Inc. Delivery systems for pharmacological agents encapsulated with proteinoids
AU606383B2 (en) * 1987-03-06 1991-02-07 Research Triangle Institute Polymer blends for selective biodegradability
FR2618329B1 (en) * 1987-07-22 1997-03-28 Dow Corning Sa METHOD OF MANUFACTURING A RING CAPABLE OF ENSURING THE RELEASE OF A THERAPEUTIC AGENT, AND RING MANUFACTURED BY THIS METHOD
US4894231A (en) * 1987-07-28 1990-01-16 Biomeasure, Inc. Therapeutic agent delivery system
DE3832162A1 (en) * 1988-09-22 1990-04-12 Lohmann Therapie Syst Lts METHOD FOR THE PRODUCTION OF COLLAGEN FOAMS IN THE FORM OF ENDLESS TAPES AND USE IN MEDICINE, COSMETICS AND HYGIENE
US4976968A (en) * 1989-02-24 1990-12-11 Clinical Technologies Associates, Inc. Anhydrous delivery systems for pharmacological agents
US4983402A (en) * 1989-02-24 1991-01-08 Clinical Technologies Associates, Inc. Orally administerable ANF
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5447728A (en) 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5443841A (en) 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
US6099856A (en) 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US5693338A (en) 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
JPH04163879A (en) * 1990-10-26 1992-06-09 Mitsumi Electric Co Ltd Contact pin fixing method
US5326568A (en) * 1991-05-03 1994-07-05 Giampapa Vincent C Method of tissue-specific delivery
US5811127A (en) 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5792451A (en) 1994-03-02 1998-08-11 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5401516A (en) * 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
ES2163444T3 (en) 1993-04-22 2002-02-01 Emisphere Tech Inc COMPOSITIONS AND METHODS FOR THE ORAL ADMINISTRATION OF PHARMACOS.
US5643957A (en) 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5709861A (en) 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US5958457A (en) 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5650386A (en) 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US5965121A (en) 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5989539A (en) 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
BR9604880A (en) 1995-03-31 1998-05-19 Emisphere Tech Inc Compound composition dosage unit form methods for administering a biologically active agent for preparing a composition for administering an active agent and for preparing a compound and pharmacological composition
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US6051258A (en) 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US5667806A (en) 1995-06-07 1997-09-16 Emisphere Technologies, Inc. Spray drying method and apparatus
DE19608423A1 (en) * 1996-03-05 1997-09-11 Merck Patent Gmbh Phased drug delivery implants
JP2000512671A (en) 1996-06-14 2000-09-26 エミスフェアー テクノロジーズ インク Microencapsulated fragrance and preparation method
US5876710A (en) 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5879681A (en) 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US5990166A (en) 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5939381A (en) 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2295316A (en) * 1994-11-25 1996-05-29 William Leslie Porter Bolus for supplying biologically beneficial substances to ruminant animals
GB2295316B (en) * 1994-11-25 1997-09-10 William Leslie Porter Bolus for supplying biologically beneficial substances to ruminant animals
US7833548B2 (en) 2002-06-18 2010-11-16 Surmodics, Inc. Bioactive agent release coating and controlled humidity method
US10390702B2 (en) 2011-12-30 2019-08-27 Kibur Medical, Inc. Implantable devices and methods for the evaluation of active agents

Also Published As

Publication number Publication date
DE2424169A1 (en) 1974-12-05
CA1045977A (en) 1979-01-09
FR2287242A1 (en) 1976-05-07
JPS5040718A (en) 1975-04-14
CH591255A5 (en) 1977-09-15
FR2287242B1 (en) 1981-06-12

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee