GB0600488D0 - Immunoglobulins - Google Patents

Immunoglobulins

Info

Publication number
GB0600488D0
GB0600488D0 GBGB0600488.1A GB0600488A GB0600488D0 GB 0600488 D0 GB0600488 D0 GB 0600488D0 GB 0600488 A GB0600488 A GB 0600488A GB 0600488 D0 GB0600488 D0 GB 0600488D0
Authority
GB
United Kingdom
Prior art keywords
immunoglobulins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0600488.1A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35997844&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB0600488(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to GBGB0600488.1A priority Critical patent/GB0600488D0/en
Publication of GB0600488D0 publication Critical patent/GB0600488D0/en
Priority to PE2007000018A priority patent/PE20081185A1/en
Priority to TW096100833A priority patent/TW200736274A/en
Priority to ARP070100082A priority patent/AR058955A1/en
Priority to BRPI0706481-0A priority patent/BRPI0706481A2/en
Priority to EP07703766A priority patent/EP1976881A2/en
Priority to CA002635972A priority patent/CA2635972A1/en
Priority to AU2007204372A priority patent/AU2007204372A1/en
Priority to PCT/EP2007/050219 priority patent/WO2007080174A2/en
Priority to EA200801520A priority patent/EA200801520A1/en
Priority to CNA2007800022973A priority patent/CN101370829A/en
Priority to JP2008549873A priority patent/JP2009523154A/en
Priority to KR1020087019555A priority patent/KR20080113201A/en
Priority to IL192207A priority patent/IL192207A0/en
Priority to NO20082767A priority patent/NO20082767L/en
Priority to ZA200805526A priority patent/ZA200805526B/en
Priority to MA31108A priority patent/MA30156B1/en
Priority to CR10161A priority patent/CR10161A/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • A61P33/12Schistosomicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
GBGB0600488.1A 2006-01-11 2006-01-11 Immunoglobulins Ceased GB0600488D0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
GBGB0600488.1A GB0600488D0 (en) 2006-01-11 2006-01-11 Immunoglobulins
PE2007000018A PE20081185A1 (en) 2006-01-11 2007-01-09 ANTIBODIES THAT BIND HUMAN INTERLEUKIN 13 (IL-13) AND COMPOSITIONS THAT UNDERSTAND IT
TW096100833A TW200736274A (en) 2006-01-11 2007-01-09 Immunoglobulins
ARP070100082A AR058955A1 (en) 2006-01-11 2007-01-09 IMMUNGLOBULINS THAT JOIN INTERLEUQUINA 13
KR1020087019555A KR20080113201A (en) 2006-01-11 2007-01-10 Chimeric and humanised anti-human il-13 antibodies
EP07703766A EP1976881A2 (en) 2006-01-11 2007-01-10 Chimeric and humanised anti-human il-13 antibodies
AU2007204372A AU2007204372A1 (en) 2006-01-11 2007-01-10 Chimeric and humanised anti-human IL-13 antibodies
JP2008549873A JP2009523154A (en) 2006-01-11 2007-01-10 Chimeric and humanized anti-human IL-13 antibodies
CA002635972A CA2635972A1 (en) 2006-01-11 2007-01-10 Chimeric and humanised anti-human il-13 antibodies
BRPI0706481-0A BRPI0706481A2 (en) 2006-01-11 2007-01-10 antibody or antigen-binding fragment thereof, humanized antibody, antigen-binding fragment, transformed or transfected recombinant host cell, methods of producing an antibody, for treating a human patient afflicted with a disease, to prevent acute asthmatic attacks in a human patient , and to reduce the frequency and / or mitigate the effects of acute asthmatic attacks on a human patient, pharmaceutical composition, kit of parts, and use of an antibody or antigen-binding fragment thereof.
PCT/EP2007/050219 WO2007080174A2 (en) 2006-01-11 2007-01-10 Chimeric and humanised anti-human il-13 antibodies
EA200801520A EA200801520A1 (en) 2006-01-11 2007-01-10 CHEMICAL AND HUMANIZED ANTIBODIES AGAINST HUMAN INTERLEUKIN-13 (IL-13)
CNA2007800022973A CN101370829A (en) 2006-01-11 2007-01-10 Chimeric and humanised anti-human IL-13 antibodies
IL192207A IL192207A0 (en) 2006-01-11 2008-06-16 Chimeric and humanised anti-human il -13 antibodies
NO20082767A NO20082767L (en) 2006-01-11 2008-06-16 Chimeric and humanized anti-human IL-13 antibodies
ZA200805526A ZA200805526B (en) 2006-01-11 2008-06-24 Chimeric and humanised anti-human IL-13 antibodies
MA31108A MA30156B1 (en) 2006-01-11 2008-07-11 IMMUNOGLOBULIN
CR10161A CR10161A (en) 2006-01-11 2008-07-17 IMMUNOGLOBULINS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0600488.1A GB0600488D0 (en) 2006-01-11 2006-01-11 Immunoglobulins

Publications (1)

Publication Number Publication Date
GB0600488D0 true GB0600488D0 (en) 2006-02-22

Family

ID=35997844

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0600488.1A Ceased GB0600488D0 (en) 2006-01-11 2006-01-11 Immunoglobulins

Country Status (18)

Country Link
EP (1) EP1976881A2 (en)
JP (1) JP2009523154A (en)
KR (1) KR20080113201A (en)
CN (1) CN101370829A (en)
AR (1) AR058955A1 (en)
AU (1) AU2007204372A1 (en)
BR (1) BRPI0706481A2 (en)
CA (1) CA2635972A1 (en)
CR (1) CR10161A (en)
EA (1) EA200801520A1 (en)
GB (1) GB0600488D0 (en)
IL (1) IL192207A0 (en)
MA (1) MA30156B1 (en)
NO (1) NO20082767L (en)
PE (1) PE20081185A1 (en)
TW (1) TW200736274A (en)
WO (1) WO2007080174A2 (en)
ZA (1) ZA200805526B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR058104A1 (en) 2005-10-21 2008-01-23 Novartis Ag ORGANIC COMPOUNDS
JP5420399B2 (en) 2006-05-25 2014-02-19 グラクソ グループ リミテッド Modified humanized anti-interleukin-18 antibody
EP2050764A1 (en) * 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
KR20110092328A (en) * 2008-11-26 2011-08-17 글락소 그룹 리미티드 Ligands that bind il-13
KR101579771B1 (en) 2009-03-05 2015-12-28 애브비 인코포레이티드 IL-17 binding proteins
GB0904214D0 (en) 2009-03-11 2009-04-22 Ucb Pharma Sa Biological products
JP5919188B2 (en) 2009-05-28 2016-05-18 グラクソ グループ リミテッドGlaxo Group Limited IL-13 binding protein
HUE053489T2 (en) * 2009-10-20 2021-06-28 Abbvie Inc Isolation and purification of anti-il-13 antibodies using protein a affinity chromatography
DK2627673T3 (en) * 2010-10-15 2017-11-06 Medimmune Ltd THERAPY TO IMPROVE LUNGE FUNCTION
KR101615420B1 (en) 2010-12-16 2016-04-26 제넨테크, 인크. Diagnosis and treatments relating to th2 inhibition
EP2686014A1 (en) 2011-03-16 2014-01-22 Sanofi Uses of a dual v region antibody-like protein
AR098155A1 (en) 2013-10-23 2016-05-04 Genentech Inc METHODS TO DIAGNOSTIC AND TREAT EOSYNOPHYL DISORDERS
AU2015218631A1 (en) 2014-02-21 2016-08-11 Genentech, Inc. Anti-IL-13/IL-17 bispecific antibodies and uses thereof
CA2943326A1 (en) 2014-04-11 2015-10-15 Novartis Ag Methods of selectively treating asthma using il-13 antagonists
KR20170127011A (en) 2015-03-16 2017-11-20 제넨테크, 인크. Methods for detecting and quantifying IL-13 and for diagnosing and treating TH2-related diseases
EP3433615A1 (en) 2016-03-21 2019-01-30 Institut National de la Sante et de la Recherche Medicale (INSERM) Methods for diagnosis and treatment of solar lentigo
JPWO2018135653A1 (en) * 2017-01-23 2020-01-09 学校法人 東洋大学 Anti-EPHA2 antibody and immunological detection of EPHA2 using the same
CN109776677B (en) * 2017-11-15 2023-11-03 尚华科创投资管理(江苏)有限公司 Humanized anti-IL-13 antibody and preparation method and application thereof
CN107909501B (en) * 2017-12-05 2020-12-01 创新先进技术有限公司 Smell and behavior association method, smell social method and device
CA3226165A1 (en) 2018-02-09 2019-08-15 Genentech, Inc. Therapeutic and diagnostic methods for mast cell-mediated inflammatory diseases
WO2020092015A1 (en) 2018-11-02 2020-05-07 University Of Rochester Therapeutic mitigation of epithelial infection
EP3938405A4 (en) * 2019-03-20 2022-12-28 Javelin Oncology, Inc. Anti-adam12 antibodies and chimeric antigen receptors, and compositions and methods comprising

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003259374A1 (en) * 2002-08-30 2004-03-19 Glaxo Group Limited Vaccine comprising il-13 and an adjuvant
WO2004096849A2 (en) * 2003-04-25 2004-11-11 University Of Manitoba Peptide-based cytokine/chemokine vaccines against allergy
ATE552850T1 (en) * 2003-12-23 2012-04-15 Genentech Inc NEW ANTI-IL 13 ANTIBODIES AND USES THEREOF
US7501121B2 (en) * 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
TWI307630B (en) * 2004-07-01 2009-03-21 Glaxo Group Ltd Immunoglobulins

Also Published As

Publication number Publication date
NO20082767L (en) 2008-10-06
CA2635972A1 (en) 2007-07-19
TW200736274A (en) 2007-10-01
CN101370829A (en) 2009-02-18
WO2007080174A3 (en) 2007-12-06
KR20080113201A (en) 2008-12-29
MA30156B1 (en) 2009-01-02
CR10161A (en) 2008-11-26
JP2009523154A (en) 2009-06-18
BRPI0706481A2 (en) 2011-03-29
EP1976881A2 (en) 2008-10-08
AU2007204372A1 (en) 2007-07-19
AR058955A1 (en) 2008-03-05
EA200801520A1 (en) 2009-02-27
WO2007080174A2 (en) 2007-07-19
PE20081185A1 (en) 2008-10-07
IL192207A0 (en) 2008-12-29
ZA200805526B (en) 2009-10-28

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