GB0520063D0 - Methods for regulating metabolism and diagnosing disease - Google Patents

Methods for regulating metabolism and diagnosing disease

Info

Publication number
GB0520063D0
GB0520063D0 GBGB0520063.9A GB0520063A GB0520063D0 GB 0520063 D0 GB0520063 D0 GB 0520063D0 GB 0520063 A GB0520063 A GB 0520063A GB 0520063 D0 GB0520063 D0 GB 0520063D0
Authority
GB
United Kingdom
Prior art keywords
methods
pkba
diagnosing disease
genes
adipogenesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0520063.9A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Friedrich Miescher Institute for Biomedical Research
Novartis Forschungsstiftung Zweigniederlassung Friedrich Miescher Institute for Biomedical Research
Novartis Forschungsstiftung
Original Assignee
Friedrich Miescher Institute for Biomedical Research
Novartis Forschungsstiftung Zweigniederlassung Friedrich Miescher Institut
Novartis Forschungsstiftung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Friedrich Miescher Institute for Biomedical Research, Novartis Forschungsstiftung Zweigniederlassung Friedrich Miescher Institut, Novartis Forschungsstiftung filed Critical Friedrich Miescher Institute for Biomedical Research
Priority to GBGB0520063.9A priority Critical patent/GB0520063D0/en
Publication of GB0520063D0 publication Critical patent/GB0520063D0/en
Priority to PCT/EP2006/009548 priority patent/WO2007039268A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Abstract

The present invention utilizes wild-type and PKBa-knockout mouse embryonic fibroblasts (MEFs) as well as nucleic acid microarray technology to identify genes whose expression is up-regulated in presence of PKBa during adipogenesis. Using this combined approach, we have identified genes previously unknown to be important for adipogenesis, and describe the use of these genes in drug discovery and as biomarkers.
GBGB0520063.9A 2005-10-03 2005-10-03 Methods for regulating metabolism and diagnosing disease Ceased GB0520063D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB0520063.9A GB0520063D0 (en) 2005-10-03 2005-10-03 Methods for regulating metabolism and diagnosing disease
PCT/EP2006/009548 WO2007039268A1 (en) 2005-10-03 2006-10-02 Methods for regulating metabolism and diagnosing disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0520063.9A GB0520063D0 (en) 2005-10-03 2005-10-03 Methods for regulating metabolism and diagnosing disease

Publications (1)

Publication Number Publication Date
GB0520063D0 true GB0520063D0 (en) 2005-11-09

Family

ID=35395157

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0520063.9A Ceased GB0520063D0 (en) 2005-10-03 2005-10-03 Methods for regulating metabolism and diagnosing disease

Country Status (2)

Country Link
GB (1) GB0520063D0 (en)
WO (1) WO2007039268A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958773A (en) * 1998-12-17 1999-09-28 Isis Pharmaceuticals Inc. Antisense modulation of AKT-1 expression
NZ537208A (en) * 2002-06-27 2009-02-28 Adipogen Pharmaceuticals Pty Ltd Differentiation modulating agents and uses therefor
EP2258847B2 (en) * 2002-08-05 2020-07-01 Silence Therapeutics GmbH Futher novel forms of interfering RNA molecules
KR101076146B1 (en) * 2002-08-16 2011-10-21 렉산 팔마큐티칼스, 인크. -1 use of antisense oligonucleotides to inhibit the expression of akt-1
EP1583836A4 (en) * 2002-12-11 2006-12-27 Univ Massachusetts METHOD OF INTRODUCING siRNA INTO ADIPOCYTES
EP1571157A1 (en) * 2004-03-05 2005-09-07 DeveloGen Aktiengesellschaft LIPIN1 function

Also Published As

Publication number Publication date
WO2007039268A1 (en) 2007-04-12

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)