GB0319124D0 - Chemical compounds - Google Patents
Chemical compoundsInfo
- Publication number
- GB0319124D0 GB0319124D0 GBGB0319124.4A GB0319124A GB0319124D0 GB 0319124 D0 GB0319124 D0 GB 0319124D0 GB 0319124 A GB0319124 A GB 0319124A GB 0319124 D0 GB0319124 D0 GB 0319124D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- chemical compounds
- compounds
- chemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/55—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0319124.4A GB0319124D0 (en) | 2003-08-14 | 2003-08-14 | Chemical compounds |
PCT/GB2004/003528 WO2005016870A1 (en) | 2003-08-14 | 2004-08-13 | 2-substituted benzoic acid derivatives as hm74a receptor agonists |
EP04768088A EP1670749A1 (en) | 2003-08-14 | 2004-08-13 | 2-substituted benzoic acid derivatives as hm74a receptor agonists |
JP2006523062A JP2007502264A (en) | 2003-08-14 | 2004-08-13 | 2-Substituted benzoic acid derivatives as HM74A receptor agonists |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0319124.4A GB0319124D0 (en) | 2003-08-14 | 2003-08-14 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB0319124D0 true GB0319124D0 (en) | 2003-09-17 |
Family
ID=28052522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB0319124.4A Ceased GB0319124D0 (en) | 2003-08-14 | 2003-08-14 | Chemical compounds |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1670749A1 (en) |
JP (1) | JP2007502264A (en) |
GB (1) | GB0319124D0 (en) |
WO (1) | WO2005016870A1 (en) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2004268621C1 (en) * | 2003-08-29 | 2011-08-18 | Exelixis, Inc. | c-Kit modulators and methods of use |
PE20050483A1 (en) | 2003-10-31 | 2005-08-25 | Arena Pharm Inc | TETRAZOLE DERIVATIVES OF FORMULA (I), ITS PHARMACEUTICAL COMPOSITIONS AND PROCESSES TO PRODUCE PHARMACEUTICAL COMPOSITIONS |
US20070281969A1 (en) * | 2004-11-23 | 2007-12-06 | Colletti Steven L | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment |
KR101351209B1 (en) | 2004-12-03 | 2014-02-06 | 머크 샤프 앤드 돔 코포레이션 | Substituted piperazines as CB1 antagonists |
PE20060949A1 (en) | 2004-12-23 | 2006-10-11 | Arena Pharm Inc | FUSED DERIVATIVES OF PIRAZOLE AS NIACIN RECEPTOR AGONISTS |
GB0428526D0 (en) | 2004-12-30 | 2005-02-09 | Novartis Ag | Organic compounds |
EP1856053A1 (en) | 2005-01-14 | 2007-11-21 | Millennium Pharmaceuticals, Inc. | Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity |
US20080221108A1 (en) * | 2005-02-14 | 2008-09-11 | Richard Hatley | Anthranilic Acid Derivatives As Hm74A Receptor Agonists |
GB0503054D0 (en) * | 2005-02-14 | 2005-03-23 | Smithkline Beecham Corp | Chemical compounds |
GB0503053D0 (en) * | 2005-02-14 | 2005-03-23 | Smithkline Beecham Corp | Chemical compounds |
GB0503056D0 (en) * | 2005-02-14 | 2005-03-23 | Smithkline Beecham Corp | Chemical compounds |
AU2006236939A1 (en) * | 2005-04-13 | 2006-10-26 | Merck Sharp & Dohme Corp. | Niacin receptor agonists, compositions containing such compounds and methods of treatment |
CN101193853B (en) * | 2005-06-14 | 2011-11-23 | 霍夫曼-拉罗奇有限公司 | Anthranilic acid derivatives |
PT1901731E (en) * | 2005-06-28 | 2011-05-11 | Merck Sharp & Dohme | Niacin receptor agonists, compositions containing such compounds and methods of treatment |
AR055369A1 (en) * | 2005-08-10 | 2007-08-22 | Smithkline Beecham Corp | COMPOUNDS DERIVED FROM XANTINA, ITS USE TO PREPARE A MEDICINAL PRODUCT FOR THE TREATMENT OF A DISEASE MEDIATED BY THE RECEIVER HM74A, FORMULATIONS AND PHARMACEUTICAL COMBINATION THAT INCLUDE IT AND METHOD OF PREPARATION OF THE SAME |
GB0516462D0 (en) * | 2005-08-10 | 2005-09-14 | Smithkline Beecham Corp | Novel compounds |
GB0516464D0 (en) * | 2005-08-10 | 2005-09-14 | Smithkline Beecham Corp | Novel compounds |
CA2620570A1 (en) * | 2005-08-29 | 2007-03-08 | Merck & Co., Inc. | Niacin receptor agonists, compositions containing such compounds and methods of treatment |
US20110028462A1 (en) * | 2005-09-20 | 2011-02-03 | Colletti Steven L | Niacin Receptor Agonists, compositions Containing Such Compounds and Methods of Treatment |
AU2006331731A1 (en) * | 2005-12-20 | 2007-07-05 | Merck Sharp & Dohme Corp. | Niacin receptor agonists, compositions containing such compounds and methods of treatment |
KR101384572B1 (en) * | 2005-12-30 | 2014-04-24 | 아버 비타 코포레이션 | Small molecule inhibitors of pdz interactions |
US8633160B2 (en) | 2005-12-30 | 2014-01-21 | Nono Inc. | Small molecule inhibitors of PDZ interactions |
US20090062269A1 (en) * | 2006-02-07 | 2009-03-05 | Subharekha Raghavan | Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment |
EP2010512A4 (en) * | 2006-04-11 | 2010-02-24 | Merck & Co Inc | Niacin receptor agonists, compositions containing such compounds and methods of treatment |
US8071625B2 (en) | 2006-08-02 | 2011-12-06 | Cytokinetics, Inc. | Certain chemical entities, compositions, and methods |
US8063082B2 (en) * | 2006-08-02 | 2011-11-22 | Cytokinetics, Inc. | Certain chemical entities, compositions, and methods |
WO2008016676A2 (en) * | 2006-08-02 | 2008-02-07 | Cytokinetics, Incorporated | Certain chemical entities, compositions, and methods |
WO2008069611A1 (en) * | 2006-12-08 | 2008-06-12 | Korea Research Institute Of Chemical Technology | N-phenylamide derivative, process for the preparation thereof, and composition for preventing or treating ischemic diseases comprising same |
KR100832750B1 (en) | 2006-12-08 | 2008-05-27 | 한국화학연구원 | Composition for preventing or treating an ischemic disease containing n-phenylamide derivatives |
WO2008144423A2 (en) * | 2007-05-15 | 2008-11-27 | Medical College Of Georgia Research Institute, Inc. | Compositions comprising a gpr109 ligand for treating disorders of the digestive tract and/or cancer |
JP5670731B2 (en) | 2007-08-15 | 2015-02-18 | サイトキネティクス・インコーポレーテッドCytokinetics Incorporated | Certain chemicals, compositions, and methods |
US8415479B2 (en) | 2008-03-31 | 2013-04-09 | Renascience Co., Ltd. | Inhibitor of plasminogen activator inhibitor-1 |
CN102378753B (en) * | 2009-03-31 | 2016-03-02 | 肾脏科学股份有限公司 | Plasminogen activator-1 inhibitor |
US8664425B2 (en) * | 2010-02-02 | 2014-03-04 | Honeywell International Inc. | Bluegreen fluorescent compounds |
WO2012034116A2 (en) * | 2010-09-10 | 2012-03-15 | The Johns Hopkins University | Small molecules as epigenetic modulators of lysine-specific demethylase 1 and methods of treating disorders |
WO2013092786A1 (en) * | 2011-12-23 | 2013-06-27 | Norgine B.V. | Compositions comprising cetilistat |
JP5840324B2 (en) | 2013-04-15 | 2016-01-06 | 株式会社レナサイエンス | New uses of PAI-1 inhibitors |
CN104418764B (en) * | 2013-09-11 | 2017-02-01 | 上海伊明化学科技有限公司 | Method for synthesizing 4-hydroxy benzenepropionamido benzoic acid |
ES2578377B1 (en) * | 2014-12-22 | 2017-05-04 | Consejo Superior De Investigaciones Científicas (Csic) | DREAM CALCIUM NEURONAL SENSOR MODULATING COMPOUNDS AND THERAPEUTIC USES. |
CN106511110B (en) * | 2016-10-25 | 2019-10-01 | 福州美乐莲生物科技有限公司 | Application and its synthetic method of the dihydro oat alkaloid D salt compounds as cosmetic active ingredient |
WO2019034693A1 (en) | 2017-08-15 | 2019-02-21 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors |
KR20200041919A (en) | 2017-08-15 | 2020-04-22 | 인플라좀 리미티드 | Sulfonylurea and sulfonylthioureas as NLRP3 inhibitors |
US11542255B2 (en) | 2017-08-15 | 2023-01-03 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
US11905252B2 (en) | 2018-03-02 | 2024-02-20 | Inflazome Limited | Compounds |
EP3662908A1 (en) * | 2018-12-04 | 2020-06-10 | Consejo Superior de Investigaciones Cientificas (CSIC) | Modulating compounds of kchip2 and its use for the treatment of cardiovascular pathologies |
CN109553550B (en) * | 2018-12-29 | 2022-02-22 | 上海克琴科技有限公司 | Method for synthesizing dihydrooat alkaloid |
CN112939803B (en) * | 2021-02-07 | 2023-07-18 | 郑州轻工业大学 | Preparation process of dihydro oat alkaloid D |
CN114478296A (en) * | 2022-02-14 | 2022-05-13 | 河南旭瑞新材料科技有限公司 | Preparation method of dihydrooat alkaloid |
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JPS59122449A (en) * | 1982-12-28 | 1984-07-14 | Kissei Pharmaceut Co Ltd | Preparation of aromatic carboxylic acid amide derivative |
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CA1338238C (en) * | 1988-01-07 | 1996-04-09 | David John Carini | Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids |
US5808144A (en) * | 1995-11-27 | 1998-09-15 | Teijin Limited | Benzene derivatives |
FR2763334A1 (en) * | 1997-05-13 | 1998-11-20 | Lipha | Piperazino alkyl anthranilic acid amide |
BR9811845A (en) * | 1997-08-05 | 2000-08-08 | American Home Prod | Analogs of anthranilic acid |
CN1265643A (en) * | 1997-08-05 | 2000-09-06 | 美国家用产品公司 | Anthranilic acid analogs |
EP1101755B1 (en) * | 1998-07-24 | 2004-10-06 | Teijin Limited | Anthranilic acid derivatives |
ATE299499T1 (en) * | 1998-11-09 | 2005-07-15 | Black James Foundation | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS |
AR022204A1 (en) * | 1999-01-08 | 2002-09-04 | Norgine Bv | COMPOUND, PROCESS FOR PREPARATION, PHARMACEUTICAL COMPOSITION AND EDIBLE PRODUCT THAT UNDERSTANDS IT. |
CA2400264A1 (en) * | 2000-02-15 | 2001-08-23 | Teijin Limited | Cancer remedy comprising anthranilic acid derivative as active ingredient |
DE10133665A1 (en) * | 2001-07-11 | 2003-01-30 | Boehringer Ingelheim Pharma | Carboxylic acid derivatives, medicaments containing these compounds, their use and preparation |
-
2003
- 2003-08-14 GB GBGB0319124.4A patent/GB0319124D0/en not_active Ceased
-
2004
- 2004-08-13 WO PCT/GB2004/003528 patent/WO2005016870A1/en active Application Filing
- 2004-08-13 JP JP2006523062A patent/JP2007502264A/en not_active Withdrawn
- 2004-08-13 EP EP04768088A patent/EP1670749A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2007502264A (en) | 2007-02-08 |
WO2005016870A1 (en) | 2005-02-24 |
EP1670749A1 (en) | 2006-06-21 |
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