FR2902428B1 - NOVEL DIAZENIUMDIOLATE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME - Google Patents

NOVEL DIAZENIUMDIOLATE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Info

Publication number
FR2902428B1
FR2902428B1 FR0605318A FR0605318A FR2902428B1 FR 2902428 B1 FR2902428 B1 FR 2902428B1 FR 0605318 A FR0605318 A FR 0605318A FR 0605318 A FR0605318 A FR 0605318A FR 2902428 B1 FR2902428 B1 FR 2902428B1
Authority
FR
France
Prior art keywords
preparing
pharmaceutical compositions
compositions containing
containing same
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0605318A
Other languages
French (fr)
Other versions
FR2902428A1 (en
Inventor
Alexis Cordi
Laure Haberkorn
Tony Verbeuren
Christine Courchay
Serge Simonet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Priority to FR0605318A priority Critical patent/FR2902428B1/en
Priority to PCT/FR2007/000989 priority patent/WO2007144512A2/en
Priority to ARP070102626A priority patent/AR061377A1/en
Publication of FR2902428A1 publication Critical patent/FR2902428A1/en
Application granted granted Critical
Publication of FR2902428B1 publication Critical patent/FR2902428B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0605318A 2006-06-15 2006-06-15 NOVEL DIAZENIUMDIOLATE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Expired - Fee Related FR2902428B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR0605318A FR2902428B1 (en) 2006-06-15 2006-06-15 NOVEL DIAZENIUMDIOLATE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
PCT/FR2007/000989 WO2007144512A2 (en) 2006-06-15 2007-06-14 Diazeniumdiolate derivatives, method for the preparation thereof, pharmaceutical compositions thereof, and use of same in the fields of hypertension and cardiovascular pathologies
ARP070102626A AR061377A1 (en) 2006-06-15 2007-06-15 DIAZENIODIOLATE DERIVATIVES, PREPARATION PROCEDURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES IN CARDIOVASCULAR PATHOLOGIES.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0605318A FR2902428B1 (en) 2006-06-15 2006-06-15 NOVEL DIAZENIUMDIOLATE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Publications (2)

Publication Number Publication Date
FR2902428A1 FR2902428A1 (en) 2007-12-21
FR2902428B1 true FR2902428B1 (en) 2008-08-15

Family

ID=37575276

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0605318A Expired - Fee Related FR2902428B1 (en) 2006-06-15 2006-06-15 NOVEL DIAZENIUMDIOLATE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

Country Status (3)

Country Link
AR (1) AR061377A1 (en)
FR (1) FR2902428B1 (en)
WO (1) WO2007144512A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008005484A1 (en) * 2008-01-22 2009-07-23 Schaper, Wolfgang, Dr. Induction and promotion of arteriogenesis
JP2011510082A (en) * 2008-01-24 2011-03-31 メルク・シャープ・エンド・ドーム・コーポレイション Angiotensin II receptor antagonist
AU2009210484A1 (en) 2008-02-08 2009-08-13 Merck Sharp & Dohme Corp. Angiotensin II receptor antagonists
EP2498605B1 (en) * 2009-10-29 2014-08-27 Merck Sharp & Dohme Corp. Diuretics
US8648058B2 (en) 2010-02-12 2014-02-11 Merck Sharp & Dohme Corp. Diazeniumdiolate cyclopentyl derivatives
EP2571351B1 (en) 2010-05-21 2016-09-14 Merck Sharp & Dohme Corp. Diazeniumdiolate cyclohexyl derivatives
CA2814752A1 (en) 2010-10-29 2012-05-03 Merck Sharp & Dohme Corp. Diazeniumdiolate heterocyclic derivatives
RU2013138391A (en) * 2011-01-19 2015-02-27 Мерк Шарп Энд Домэ Корп. DIAZENIUM DIOLATE DERIVATIVES
JO3350B1 (en) 2011-03-07 2019-03-13 Merck Sharp & Dohme Heterocyclic derivatives containing primary amino groups and diazeniumdiolates
WO2012151114A1 (en) 2011-05-02 2012-11-08 Merck Sharp & Dohme Corp. Diazeniumdiolate cyclohexyl derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
NO20030115D0 (en) * 2003-01-09 2003-01-09 Amersham Health As Imaging agents

Also Published As

Publication number Publication date
WO2007144512A2 (en) 2007-12-21
AR061377A1 (en) 2008-08-20
WO2007144512A3 (en) 2008-03-20
FR2902428A1 (en) 2007-12-21

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Effective date: 20100226