FR2696461B1 - New derivatives of taxol analogs, their preparation and compositions containing them. - Google Patents

New derivatives of taxol analogs, their preparation and compositions containing them.

Info

Publication number
FR2696461B1
FR2696461B1 FR9211744A FR9211744A FR2696461B1 FR 2696461 B1 FR2696461 B1 FR 2696461B1 FR 9211744 A FR9211744 A FR 9211744A FR 9211744 A FR9211744 A FR 9211744A FR 2696461 B1 FR2696461 B1 FR 2696461B1
Authority
FR
France
Prior art keywords
preparation
compositions containing
new derivatives
taxol analogs
taxol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9211744A
Other languages
French (fr)
Other versions
FR2696461A1 (en
Inventor
Jean-Dominique Bourzat
Alain Commercon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Priority to FR9211744A priority Critical patent/FR2696461B1/en
Priority to MX9305769A priority patent/MX9305769A/en
Priority to ZA937321A priority patent/ZA937321B/en
Priority to PCT/FR1993/000970 priority patent/WO1994007880A1/en
Priority to AU51153/93A priority patent/AU5115393A/en
Publication of FR2696461A1 publication Critical patent/FR2696461A1/en
Application granted granted Critical
Publication of FR2696461B1 publication Critical patent/FR2696461B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
FR9211744A 1992-10-05 1992-10-05 New derivatives of taxol analogs, their preparation and compositions containing them. Expired - Fee Related FR2696461B1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR9211744A FR2696461B1 (en) 1992-10-05 1992-10-05 New derivatives of taxol analogs, their preparation and compositions containing them.
MX9305769A MX9305769A (en) 1992-10-05 1993-09-21 NEW DERIVATIVES OF ANALOGS OF TAXOL, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
ZA937321A ZA937321B (en) 1992-10-05 1993-10-01 Taxol derivatives their preparation and compositions containing them
PCT/FR1993/000970 WO1994007880A1 (en) 1992-10-05 1993-10-04 Novel derivatives of taxol analogues, preparation thereof and compositions containing them
AU51153/93A AU5115393A (en) 1992-10-05 1993-10-04 Novel derivatives of taxol analogues, preparation thereof and compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9211744A FR2696461B1 (en) 1992-10-05 1992-10-05 New derivatives of taxol analogs, their preparation and compositions containing them.

Publications (2)

Publication Number Publication Date
FR2696461A1 FR2696461A1 (en) 1994-04-08
FR2696461B1 true FR2696461B1 (en) 1994-11-10

Family

ID=9434122

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9211744A Expired - Fee Related FR2696461B1 (en) 1992-10-05 1992-10-05 New derivatives of taxol analogs, their preparation and compositions containing them.

Country Status (5)

Country Link
AU (1) AU5115393A (en)
FR (1) FR2696461B1 (en)
MX (1) MX9305769A (en)
WO (1) WO1994007880A1 (en)
ZA (1) ZA937321B (en)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
ATE420628T1 (en) 1993-07-19 2009-01-15 Angiotech Pharm Inc ANTI-ANGIogenic AGENTS AND METHODS OF USE THEREOF
EP0914116B1 (en) * 1996-05-22 2000-10-11 Protarga Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and taxotere
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
WO1998013359A1 (en) * 1996-09-24 1998-04-02 Marigen S.A. Ultramicroemulsion of spontaneously dispersible concentrates of esters of baccatin-iii compounds with antitumor and antiviral effect
US6515016B2 (en) 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CA2307393A1 (en) 2000-05-01 2001-11-01 The University Of British Columbia Ginsenoside chemotherapy
EP2014307A3 (en) 2001-03-13 2010-12-08 Angiotech International Ag Micellar drug delivery vehicles and uses thereof
CA2444529C (en) 2001-04-20 2010-11-23 The University Of British Columbia Micellar drug delivery systems for hydrophobic drugs
CA2354471A1 (en) * 2001-07-31 2003-01-31 Florida State University Research Foundation, Inc. C10 ester substituted taxanes
US7351542B2 (en) 2002-05-20 2008-04-01 The Regents Of The University Of California Methods of modulating tubulin deacetylase activity
DE60331367D1 (en) 2002-12-30 2010-04-01 Angiotech Int Ag ACTIVE COMPOSITION OF FAST GELING POLYMERIC COMPOSITION
EP1633317A4 (en) 2003-05-16 2008-08-20 Intermune Inc Synthetic chemokine receptor ligands and methods of use thereof
SV2006002010A (en) 2004-02-13 2006-08-23 Univ Florida State Res Found REPLACED TAXANS WITH CYCLOPENTILO ESTERS IN C10
US7989490B2 (en) 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
US7846940B2 (en) 2004-03-31 2010-12-07 Cordis Corporation Solution formulations of sirolimus and its analogs for CAD treatment
US8003122B2 (en) 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
US8691780B2 (en) 2005-02-17 2014-04-08 The Board Of Trustees Of The Leland Stanford Junior University Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby
AU2007228984B2 (en) 2006-03-22 2012-05-03 Syncore Biotechnology Co., Ltd Treatment of triple receptor negative breast cancer
EP2043704B2 (en) 2006-06-30 2017-04-19 Cook Medical Technologies LLC Methods of manufacturing and modifying taxane coatings for implantable medical devices
US8409601B2 (en) 2008-03-31 2013-04-02 Cordis Corporation Rapamycin coated expandable devices
US8420110B2 (en) 2008-03-31 2013-04-16 Cordis Corporation Drug coated expandable devices
EP2276755A4 (en) 2008-03-31 2011-05-04 Univ Florida State Res Found C(10) ethyl ester and c(10) cyclopropyl ester substituted taxanes
US8273404B2 (en) 2008-05-19 2012-09-25 Cordis Corporation Extraction of solvents from drug containing polymer reservoirs
ES2530462T3 (en) 2008-05-22 2015-03-03 Galera Therapeutics Llc Combination antitumor therapy
WO2010005850A1 (en) 2008-07-08 2010-01-14 The J. David Gladstone Institutes Methods and compositions for modulating angiogenesis
US8642063B2 (en) 2008-08-22 2014-02-04 Cook Medical Technologies Llc Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
US20120303115A1 (en) 2011-05-25 2012-11-29 Dadino Ronald C Expandable devices coated with a rapamycin composition
US20120302954A1 (en) 2011-05-25 2012-11-29 Zhao Jonathon Z Expandable devices coated with a paclitaxel composition
US9956385B2 (en) 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
KR102165464B1 (en) 2012-07-19 2020-10-14 레드우드 바이오사이언스 인코포레이티드 Antibody specific for cd22 and methods of use thereof
CN104884056A (en) 2012-11-12 2015-09-02 雷德伍德生物科技股份有限公司 Compounds and methods for producing a conjugate
DK3300745T3 (en) 2013-02-15 2019-11-04 Univ California CHEMICAL ANTIGEN RECEPTOR AND METHODS FOR USING IT
JP6410790B2 (en) 2013-03-14 2018-10-24 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー Mitochondrial aldehyde dehydrogenase-2 modulator and method of use thereof
US9493413B2 (en) 2013-11-27 2016-11-15 Redwood Bioscience, Inc. Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
US9879036B2 (en) 2014-02-19 2018-01-30 Aviv Therapeutics, Inc. Mitochondrial aldehyde dehydrogenase-2 binding compounds and methods of use thereof
KR20180058759A (en) 2015-09-25 2018-06-01 제트와이 테라퓨틱스 인코포레이티드 Pharmaceutical preparations based on microparticles comprising a polysaccharide-vitamin conjugate
WO2017083637A1 (en) 2015-11-12 2017-05-18 The Board Of Trustees Of The Leland Stanford Junior University Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery
TWI760319B (en) 2015-12-30 2022-04-11 杏國新藥股份有限公司 Treatment of breast cancer
WO2017189432A1 (en) 2016-04-26 2017-11-02 R.P. Scherer Technologies, Llc Antibody conjugates and methods of making and using the same
KR20230162139A (en) 2016-06-01 2023-11-28 세르비에 아이피 유케이 리미티드 Formulations of polyalkylene oxide-asparaginase and methods of making and using the same
TW201825087A (en) 2017-01-05 2018-07-16 杏國新藥股份有限公司 Treatment of pancreatic cancer
AU2018211081A1 (en) 2017-01-18 2019-07-18 Bioatla, Inc. Chimeric antigen receptors against Axl or Ror2 and methods of use thereof
EP3388082A1 (en) 2017-04-13 2018-10-17 Galera Labs, LLC Combination cancer immunotherapy with pentaaza macrocyclic ring complex
BR112020015520A2 (en) 2018-01-31 2021-02-02 Galera Labs, Llc combination therapy for cancer with pentaaza macrocyclic ring complex and platinum-based anticancer agent
BR112020020930A2 (en) 2018-04-11 2021-03-02 Ohio State Innovation Foundation drug delivery composition, method for treating an eye disorder and kit
EP3823674A4 (en) 2018-07-18 2022-12-28 Manzanita Pharmaceuticals, Inc. Conjugates for delivering an anti-cancer agent to nerve cells, methods of use and methods of making thereof
WO2020148612A1 (en) 2019-01-14 2020-07-23 Ignite Immunotherapy, Inc. Recombinant vaccinia virus and methods of use thereof
JP2022520220A (en) 2019-02-14 2022-03-29 イグナイト イミュノセラピー インク Recombinant vaccinia virus and how to use it
BR112021019701A2 (en) 2019-04-02 2021-12-14 Kenjockety Biotechnology Inc Multispecific antibodies to efflux pump cancer antigen and compositions, reagents, kits and methods related thereto
CN115380041A (en) 2019-12-12 2022-11-22 伊格奈特免疫疗法公司 Variant oncolytic vaccinia viruses and methods of use thereof
WO2021155028A1 (en) 2020-01-29 2021-08-05 Kenjockety Biotechnology, Inc. Anti-mdr1 antibodies and uses thereof
AU2021284240A1 (en) 2020-06-04 2022-12-08 Kenjockety Biotechnology, Inc. Anti-ABCG2 antibodies and uses thereof
CN116529267A (en) 2020-06-04 2023-08-01 肯乔克蒂生物技术股份有限公司 ABCG2 efflux pump-cancer antigen multispecific antibodies and related compositions, reagents, kits and methods
BR112023000650A2 (en) 2020-07-14 2023-01-31 Pfizer RECOMBINANT VACCINIA VIRUS
AU2021338286A1 (en) 2020-09-02 2023-03-23 Kenjockety Biotechnology, Inc. Anti-ABCC1 antibodies and uses thereof
US20240010747A1 (en) 2020-11-13 2024-01-11 Kenjockety Biotechnology, Inc. Anti-mrp4 (encoded by abcc4 gene) antibodies and uses thereof
AU2022413942A1 (en) 2021-12-13 2024-05-30 William Robert Arathoon Living Trust Anti-abcb1 antibodies
WO2023159220A1 (en) 2022-02-18 2023-08-24 Kenjockety Biotechnology, Inc. Anti-cd47 antibodies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (en) * 1986-07-17 1988-09-23 Rhone Poulenc Sante TAXOL DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
MX9102128A (en) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa DERIVATIVES OF TAXANE, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5243045A (en) * 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
FR2696461A1 (en) 1994-04-08
WO1994007880A1 (en) 1994-04-14
AU5115393A (en) 1994-04-26
MX9305769A (en) 1994-05-31
ZA937321B (en) 1994-04-25

Similar Documents

Publication Publication Date Title
FR2696461B1 (en) New derivatives of taxol analogs, their preparation and compositions containing them.
FR2679230B1 (en) NOVEL DERIVATIVES OF TAXOL ANALOGS, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
FR2611203B1 (en) GEM-DIPHOSPHONIC ANALOGS OF AMETHOPTERIN (METHOTREXATE) AND DEAZA-N-10 AMETHOPTERINE DERIVATIVES. THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2711993B1 (en) Drugs containing 7H-imidazol [1,2-a] pyrazine-8-one derivatives, new compounds and their preparation.
FR2697841B1 (en) New taxane derivatives, their preparation and the pharmaceutical compositions containing them.
FR2708606B1 (en) N-phenylalkylindol-2-one derivatives, their preparation, pharmaceutical compositions containing them.
FR2697019B1 (en) New taxane derivatives, their preparation and the pharmaceutical compositions containing them.
FR2687151B1 (en) NOVEL DERIVATIVES OF BACCATIN III AND DESACETYL-10 BACCATIN III, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2607502B1 (en) IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND MEDICINAL COMPOSITIONS CONTAINING THEM
FR2705671B1 (en) New hydroxybiphenyl derivatives, their preparation and the pharmaceutical compositions containing them.
OA07539A (en) New derivatives of phenyl aliphatic acids, their preparation, their application as medicaments, and the compositions containing them.
FR2712289B1 (en) New taxicin derivatives, their preparation and the pharmaceutical compositions containing them.
OA07537A (en) New derivatives of 4 H-1,2,4-triazole, their preparation, their application as a medicament, the compositions containing them and the intermediates obtained.
FR2705094B1 (en) New lupane derivatives, their preparation and the pharmaceutical compositions containing them.
FR2705097B1 (en) New lupane derivatives, their preparation and the pharmaceutical compositions containing them.
FR2691460B1 (en) NEW TAXANE DERIVATIVES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
FR2693193B1 (en) New derivatives of 10-deacetyl baccatin III, their preparation and the pharmaceutical compositions containing them.
FR2713643B1 (en) New analogs of eburnane, process for their preparation and pharmaceutical compositions containing them.
FR2521142B1 (en) NOVEL N-METHANESULFONIC DERIVATIVES OF DEMETHYL-3-O ISTAMYCIN B, THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS CONTAINING THE SAME
FR2692581B1 (en) New peptide derivatives with bradykinin antagonist activity, their preparation process and the pharmaceutical compositions containing them.
FR2706459B1 (en) New quinolone derivatives, process for obtaining them and pharmaceutical compositions containing them.
BE867129A (en) NEW DERIVATIVES OF HYDROXY-4 THIAZOLIDINETHIONE-2, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM
FR2701952B1 (en) New cyclopeptide derivatives of angiopeptin, their preparation process and the pharmaceutical compositions containing them.
FR2677355B1 (en) NEW OXAZOLE DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2699172B1 (en) New derivatives of 4-methyl-1,3-oxazole, their preparation process and the pharmaceutical compositions containing them.

Legal Events

Date Code Title Description
ST Notification of lapse