FR2615192B1 - PROCESS FOR THE PREPARATION OF POLYMER PARTICLES OR LATEX CONSISTING OF POLYMER PARTICLES COMPRISING, IMPLANTED ON THEIR SURFACE, AMPHIPHILIC MOLECULES CARRYING IONOGENIC OR REACTIVE GROUPS - Google Patents
PROCESS FOR THE PREPARATION OF POLYMER PARTICLES OR LATEX CONSISTING OF POLYMER PARTICLES COMPRISING, IMPLANTED ON THEIR SURFACE, AMPHIPHILIC MOLECULES CARRYING IONOGENIC OR REACTIVE GROUPSInfo
- Publication number
- FR2615192B1 FR2615192B1 FR8706550A FR8706550A FR2615192B1 FR 2615192 B1 FR2615192 B1 FR 2615192B1 FR 8706550 A FR8706550 A FR 8706550A FR 8706550 A FR8706550 A FR 8706550A FR 2615192 B1 FR2615192 B1 FR 2615192B1
- Authority
- FR
- France
- Prior art keywords
- polymer particles
- particles
- implanted
- preparation
- reactive groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Polymerisation Methods In General (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Graft Or Block Polymers (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Peptides Or Proteins (AREA)
- Materials For Medical Uses (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Polyethers (AREA)
Abstract
The process comprises the following stages:
1) diffusion, into an aqueous "seed" dispersion of polymer particles, of an organosoluble polymerisation initiator, at a temperature lower than that of the initiator decomposition
2) swelling the particles by introduction of the monomer to be polymerised and of an amphiphilic compound containing an oligomeric hydrophilic block ending in an ion-forming or reactive group, at a temperature lower than that of the initiator decomposition
3) polymerisation of the monomer
4) removal of the unimplanted amphiphilic constituent
5) optionally separation of the particles.
<??>The particles or the dispersions of particles thus obtained may be employed in biology.
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8706550A FR2615192B1 (en) | 1987-05-11 | 1987-05-11 | PROCESS FOR THE PREPARATION OF POLYMER PARTICLES OR LATEX CONSISTING OF POLYMER PARTICLES COMPRISING, IMPLANTED ON THEIR SURFACE, AMPHIPHILIC MOLECULES CARRYING IONOGENIC OR REACTIVE GROUPS |
ES198888401079T ES2028321T3 (en) | 1987-05-11 | 1988-05-04 | PROCEDURE FOR THE PREPARATION OF PARTICLES OF POLYMER OR OF DARKNESS CONSTITUTED BY PARTICLES OF POLYMER THAT INCLUDE, IMPLEMENTED IN THEIR SURFACE, AMPHYPHILIC MOLECULES CARRYING IONOGENOUS OR REACTIVE GROUPS. |
AT88401079T ATE72049T1 (en) | 1987-05-11 | 1988-05-04 | PROCESS FOR THE PREPARATION OF POLYMER PARTICLES OR A LATEX OF POLYMER PARTICLES HAVING ON THEIR SURFACE AMPHIPHIL MOLECULES WITH IONOGENIC OR REACTIVE GROUPS. |
DE8888401079T DE3867900D1 (en) | 1987-05-11 | 1988-05-04 | METHOD FOR PRODUCING POLYMER PARTICLES OR A LATEX OF POLYMER PARTICLES WITH AMPHIPHILE MOLECULES ON THE SURFACE WITH IONOGENIC OR REACTIVE GROUPS. |
EP88401079A EP0291390B1 (en) | 1987-05-11 | 1988-05-04 | Process for the preparation of polymer particles or of a latex made of polymer particles having on their surface amphiphile molecules with inorganic or reactive groups |
US07/191,176 US4929662A (en) | 1987-05-11 | 1988-05-06 | Process for the preparation of polymer particles possessing, implanted on their surface, amphophilic molecules carrying ion-forming or reactive groups, and a process for the preparation of a latex comprising these particles |
AU15833/88A AU605292B2 (en) | 1987-05-11 | 1988-05-09 | Method for implanting amphiphile molecules on polymer particles |
IL86323A IL86323A (en) | 1987-05-11 | 1988-05-09 | Process for the preparation of polymer particles or of a latex made of polymer particles having on their surface amphiphilic molecules with ionogenic or reactive groups |
BR8802279A BR8802279A (en) | 1987-05-11 | 1988-05-10 | PROCESS OF PREPARATION OF POLYMER PARTICLES BEHAVING, IMPLANTED ON THEIR SURFACE, AMPHYPHYLIC MOLECULES, BEARING IONOGENOUS OR REACTIVE GROUPS TO PARTICLES OR WATER DISPERSES OF PARTICLES |
CN88102645A CN1031539A (en) | 1987-05-11 | 1988-05-10 | Be fixed with on its surface band ionization or active group amphiphile, amphiphilic molecule polymer beads or by the preparation method of its latex that constitutes |
DK256188A DK256188A (en) | 1987-05-11 | 1988-05-10 | PROCEDURE FOR PREPARING POLYMER PARTICLES OR POLYMER LATEXES WITH IMPLANTED AMPHIPHITE MOLECULES |
PT87448A PT87448B (en) | 1987-05-11 | 1988-05-10 | PROCESS FOR THE PREPARATION OF POLYMER OR LATEX PARTICLES CONSTITUTED BY POLYMER PARTICLES UNDERSTANDING, IMPLANTED ON THEIR SURFACE, ANTIFILIC MOLECULES THAT MAY CONTAIN IONOGENIC OR REACTIVE GROUPS |
JP63112682A JPH0667973B2 (en) | 1987-05-11 | 1988-05-11 | Method for producing polymer particles containing amphipathic compound having ionogen group or reactive group implanted on the surface or latex comprising the particles |
KR1019880005485A KR910009291B1 (en) | 1987-05-11 | 1988-05-11 | Process for the preparation of polymer particles possessing implanted on their surface amphophilic molecules carrying ion-forming or reactive groups and a process for the preparation of a latex comprising these particles |
GR920400164T GR3003741T3 (en) | 1987-05-11 | 1992-02-07 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8706550A FR2615192B1 (en) | 1987-05-11 | 1987-05-11 | PROCESS FOR THE PREPARATION OF POLYMER PARTICLES OR LATEX CONSISTING OF POLYMER PARTICLES COMPRISING, IMPLANTED ON THEIR SURFACE, AMPHIPHILIC MOLECULES CARRYING IONOGENIC OR REACTIVE GROUPS |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2615192A1 FR2615192A1 (en) | 1988-11-18 |
FR2615192B1 true FR2615192B1 (en) | 1989-12-01 |
Family
ID=9350946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8706550A Expired FR2615192B1 (en) | 1987-05-11 | 1987-05-11 | PROCESS FOR THE PREPARATION OF POLYMER PARTICLES OR LATEX CONSISTING OF POLYMER PARTICLES COMPRISING, IMPLANTED ON THEIR SURFACE, AMPHIPHILIC MOLECULES CARRYING IONOGENIC OR REACTIVE GROUPS |
Country Status (15)
Country | Link |
---|---|
US (1) | US4929662A (en) |
EP (1) | EP0291390B1 (en) |
JP (1) | JPH0667973B2 (en) |
KR (1) | KR910009291B1 (en) |
CN (1) | CN1031539A (en) |
AT (1) | ATE72049T1 (en) |
AU (1) | AU605292B2 (en) |
BR (1) | BR8802279A (en) |
DE (1) | DE3867900D1 (en) |
DK (1) | DK256188A (en) |
ES (1) | ES2028321T3 (en) |
FR (1) | FR2615192B1 (en) |
GR (1) | GR3003741T3 (en) |
IL (1) | IL86323A (en) |
PT (1) | PT87448B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5166000A (en) * | 1991-10-10 | 1992-11-24 | Nanofilm Corporation | Method of applying thin films of amphiphilic molecules to substrates |
FR2735778B1 (en) * | 1995-06-22 | 1997-08-22 | Prolabo Sa | NEW LATEX OF CALIBRATED SINGLE-SPRAY MAGNETISABLE MICROSPHERES, PROCESS FOR PREPARING AND USING THE LATEX IN CHEMISTRY OR BIOLOGY |
US5981296A (en) * | 1997-02-18 | 1999-11-09 | Dade Behring Inc. | Stabilization of particle reagents |
CN107076741B (en) * | 2014-09-02 | 2020-11-24 | 美迪恩斯生命科技株式会社 | Polymer microparticles for loading physiologically active substance and process for producing the same |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2461920A (en) * | 1944-01-25 | 1949-02-15 | Du Pont | Polyhydric alcohol mixed esters |
FR1537741A (en) * | 1967-06-09 | 1968-08-30 | Wolfen Filmfab Veb | Process for preparing vinyl ion exchange resins |
JPS5443572B2 (en) * | 1974-07-08 | 1979-12-20 | ||
US4157323A (en) * | 1976-06-09 | 1979-06-05 | California Institute Of Technology | Metal containing polymeric functional microspheres |
US4217344A (en) * | 1976-06-23 | 1980-08-12 | L'oreal | Compositions containing aqueous dispersions of lipid spheres |
FR2450263A1 (en) * | 1979-02-28 | 1980-09-26 | Dow Chemical Co | Coupling protein to latex particles having epoxy gps. - for use in immunological analysis esp. pregnancy testing |
FR2480764B1 (en) * | 1980-04-18 | 1985-10-04 | Rhone Poulenc Spec Chim | LATEX OF MAGNETIC POLYMERS AND PREPARATION METHOD |
US4333969A (en) * | 1980-12-23 | 1982-06-08 | Atlantic Richfield Company | Process for producing styrenic polymer beads of preferred bead size |
FI842992A0 (en) * | 1984-07-26 | 1984-07-26 | Labsystems Oy | IMMUNOLOGISKT DEFINITIONSFOERFARANDE. |
DE3523319A1 (en) * | 1985-06-29 | 1987-01-08 | Basf Ag | BINDING AGENT FOR AQUEOUS, PHYSICAL DRYING CORROSION PROTECTION COATINGS BASED ON A POLYMER DISPERSION CONTAINING PHOSPHORIC ACID MONOALKYLESTER |
US4855127A (en) * | 1986-07-07 | 1989-08-08 | Dow Corning Corporation | Lattice-entrapped composition |
-
1987
- 1987-05-11 FR FR8706550A patent/FR2615192B1/en not_active Expired
-
1988
- 1988-05-04 ES ES198888401079T patent/ES2028321T3/en not_active Expired - Lifetime
- 1988-05-04 DE DE8888401079T patent/DE3867900D1/en not_active Expired - Lifetime
- 1988-05-04 EP EP88401079A patent/EP0291390B1/en not_active Expired - Lifetime
- 1988-05-04 AT AT88401079T patent/ATE72049T1/en not_active IP Right Cessation
- 1988-05-06 US US07/191,176 patent/US4929662A/en not_active Expired - Lifetime
- 1988-05-09 IL IL86323A patent/IL86323A/en unknown
- 1988-05-09 AU AU15833/88A patent/AU605292B2/en not_active Ceased
- 1988-05-10 CN CN88102645A patent/CN1031539A/en active Pending
- 1988-05-10 PT PT87448A patent/PT87448B/en not_active IP Right Cessation
- 1988-05-10 DK DK256188A patent/DK256188A/en not_active Application Discontinuation
- 1988-05-10 BR BR8802279A patent/BR8802279A/en unknown
- 1988-05-11 KR KR1019880005485A patent/KR910009291B1/en active IP Right Grant
- 1988-05-11 JP JP63112682A patent/JPH0667973B2/en not_active Expired - Lifetime
-
1992
- 1992-02-07 GR GR920400164T patent/GR3003741T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
FR2615192A1 (en) | 1988-11-18 |
DK256188D0 (en) | 1988-05-10 |
PT87448A (en) | 1989-05-31 |
JPH0667973B2 (en) | 1994-08-31 |
JPS6465102A (en) | 1989-03-10 |
GR3003741T3 (en) | 1993-03-16 |
AU605292B2 (en) | 1991-01-10 |
US4929662A (en) | 1990-05-29 |
CN1031539A (en) | 1989-03-08 |
DK256188A (en) | 1989-01-19 |
KR910009291B1 (en) | 1991-11-09 |
KR880014014A (en) | 1988-12-22 |
ATE72049T1 (en) | 1992-02-15 |
ES2028321T3 (en) | 1992-07-01 |
PT87448B (en) | 1992-08-31 |
EP0291390B1 (en) | 1992-01-22 |
EP0291390A1 (en) | 1988-11-17 |
AU1583388A (en) | 1988-11-17 |
BR8802279A (en) | 1988-12-13 |
IL86323A0 (en) | 1988-11-15 |
DE3867900D1 (en) | 1992-03-05 |
IL86323A (en) | 1991-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |