FR2356427A2 - Compsn. for treatment of cellulitis and lipidic excess - contains mucopolysaccharidases opt. with hyaluronidase and active cpds. such as triiodo-thyroacetic acid, acetazolamide and aescin - Google Patents

Compsn. for treatment of cellulitis and lipidic excess - contains mucopolysaccharidases opt. with hyaluronidase and active cpds. such as triiodo-thyroacetic acid, acetazolamide and aescin

Info

Publication number
FR2356427A2
FR2356427A2 FR7620218A FR7620218A FR2356427A2 FR 2356427 A2 FR2356427 A2 FR 2356427A2 FR 7620218 A FR7620218 A FR 7620218A FR 7620218 A FR7620218 A FR 7620218A FR 2356427 A2 FR2356427 A2 FR 2356427A2
Authority
FR
France
Prior art keywords
mucopolysaccharidases
aescin
hyaluronidase
cpds
triiodo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7620218A
Other languages
French (fr)
Other versions
FR2356427B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ANA LABORATOIRES
Original Assignee
ANA LABORATOIRES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ANA LABORATOIRES filed Critical ANA LABORATOIRES
Priority to FR7620218A priority Critical patent/FR2356427A2/en
Priority to BE1008215A priority patent/BE856006A/en
Priority to DE2729010A priority patent/DE2729010C2/en
Publication of FR2356427A2 publication Critical patent/FR2356427A2/en
Application granted granted Critical
Publication of FR2356427B2 publication Critical patent/FR2356427B2/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01035—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The compsn. contains an association of mucopolysaccharidases opt. with hyaluronidase and >=1 of the active cpds. chosen from 3,5,3'-triiodo-thyroacetic acid or its esters and salts; 3,5,3'-triiodothyrobutyric acid or its esters and salts; acetozolamide and aescin. The mucopolysaccharidases and hyaluronidase enzymes hydrolyse the mucopolysaccharides and hyaluronic acid respectively allowing intercommunication of the cellulo-fatty tissue and lipid mobilisation and giving better penetration of cpds. applied to the skin and better diffusion of cpds. administered sub-cutaneously. Acetazolamide is a carbonic anhydrase inhibitor and regulates water-metabolism and the carbon dioxide present for the local synthesis of fatty acids. Aescin has casoprotective activity and avoids oedema formation.
FR7620218A 1976-07-02 1976-07-02 Compsn. for treatment of cellulitis and lipidic excess - contains mucopolysaccharidases opt. with hyaluronidase and active cpds. such as triiodo-thyroacetic acid, acetazolamide and aescin Granted FR2356427A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR7620218A FR2356427A2 (en) 1976-07-02 1976-07-02 Compsn. for treatment of cellulitis and lipidic excess - contains mucopolysaccharidases opt. with hyaluronidase and active cpds. such as triiodo-thyroacetic acid, acetazolamide and aescin
BE1008215A BE856006A (en) 1976-07-02 1977-06-23 NEW MEDICINES FOR THE TREATMENT OF LIPID OVERLOAD AND CELLULITE
DE2729010A DE2729010C2 (en) 1976-07-02 1977-06-28 Medicines for the treatment of cellulite and obesity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7620218A FR2356427A2 (en) 1976-07-02 1976-07-02 Compsn. for treatment of cellulitis and lipidic excess - contains mucopolysaccharidases opt. with hyaluronidase and active cpds. such as triiodo-thyroacetic acid, acetazolamide and aescin

Publications (2)

Publication Number Publication Date
FR2356427A2 true FR2356427A2 (en) 1978-01-27
FR2356427B2 FR2356427B2 (en) 1978-12-15

Family

ID=9175169

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7620218A Granted FR2356427A2 (en) 1976-07-02 1976-07-02 Compsn. for treatment of cellulitis and lipidic excess - contains mucopolysaccharidases opt. with hyaluronidase and active cpds. such as triiodo-thyroacetic acid, acetazolamide and aescin

Country Status (3)

Country Link
BE (1) BE856006A (en)
DE (1) DE2729010C2 (en)
FR (1) FR2356427A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515961A1 (en) * 1977-06-03 1983-05-13 Berema Sa MEDICAMENT PREPARATIONS CONTAINING A TETRAIODOTHYROCARBOXYLIC ACID DERIVATIVE, IN PARTICULAR FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA
EP0477833A1 (en) * 1990-09-28 1992-04-01 Rosa Dr. Sternberg Ruiu Composition for therapeutic and/or cosmetic use for treatment of circulatory diseases and for aesthetic medicine treatments
EP1398024A3 (en) * 1995-06-07 2004-12-15 Karo Bio Ab uses for thyroid hormones compounds

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19721218B4 (en) 1997-05-21 2006-12-14 Dornier Medizintechnik Gmbh Using a pulse sound source
FR2774589B3 (en) * 1998-02-10 2000-01-07 Jean Noel Thorel SLIMMING COSMETIC COMPOSITIONS
AU1865100A (en) * 1998-12-23 2000-07-31 Esparma Gmbh Hyaluronate lyase used for promoting penetration in topical agents

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515961A1 (en) * 1977-06-03 1983-05-13 Berema Sa MEDICAMENT PREPARATIONS CONTAINING A TETRAIODOTHYROCARBOXYLIC ACID DERIVATIVE, IN PARTICULAR FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA
EP0477833A1 (en) * 1990-09-28 1992-04-01 Rosa Dr. Sternberg Ruiu Composition for therapeutic and/or cosmetic use for treatment of circulatory diseases and for aesthetic medicine treatments
EP1398024A3 (en) * 1995-06-07 2004-12-15 Karo Bio Ab uses for thyroid hormones compounds

Also Published As

Publication number Publication date
FR2356427B2 (en) 1978-12-15
DE2729010A1 (en) 1978-01-12
DE2729010C2 (en) 1986-11-06
BE856006A (en) 1977-12-23

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