FI943513A0 - 3-Phenylureidoazepin-2-ones and benzazepin-2-ones useful as cholecystokinin antagonists - Google Patents

3-Phenylureidoazepin-2-ones and benzazepin-2-ones useful as cholecystokinin antagonists

Info

Publication number
FI943513A0
FI943513A0 FI943513A FI943513A FI943513A0 FI 943513 A0 FI943513 A0 FI 943513A0 FI 943513 A FI943513 A FI 943513A FI 943513 A FI943513 A FI 943513A FI 943513 A0 FI943513 A0 FI 943513A0
Authority
FI
Finland
Prior art keywords
ones
phenylureidoazepin
benzazepin
useful
cholecystokinin antagonists
Prior art date
Application number
FI943513A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI943513A (en
Inventor
Iii John A Lowe
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI943513A publication Critical patent/FI943513A/en
Publication of FI943513A0 publication Critical patent/FI943513A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI943513A 1992-01-27 1994-07-26 3-Phenylureidoazepin-2-ones and benzazepin-2-ones useful as cholecystokinin antagonists FI943513A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82567792A 1992-01-27 1992-01-27
PCT/US1992/010720 WO1993015059A1 (en) 1992-01-27 1992-12-16 3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists

Publications (2)

Publication Number Publication Date
FI943513A FI943513A (en) 1994-07-26
FI943513A0 true FI943513A0 (en) 1994-07-26

Family

ID=25244657

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943513A FI943513A0 (en) 1992-01-27 1994-07-26 3-Phenylureidoazepin-2-ones and benzazepin-2-ones useful as cholecystokinin antagonists

Country Status (19)

Country Link
EP (1) EP0625145A1 (en)
JP (1) JPH07503465A (en)
KR (1) KR950700257A (en)
CN (1) CN1074903A (en)
AU (1) AU3276193A (en)
BR (1) BR9207071A (en)
CA (1) CA2117367A1 (en)
CZ (1) CZ391092A3 (en)
FI (1) FI943513A0 (en)
HU (1) HUT70496A (en)
IL (1) IL104472A0 (en)
MX (1) MX9300409A (en)
NO (1) NO942775L (en)
NZ (1) NZ245759A (en)
RU (1) RU94038063A (en)
TW (1) TW213901B (en)
WO (1) WO1993015059A1 (en)
YU (1) YU4393A (en)
ZA (1) ZA93582B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2097688A1 (en) * 1993-07-14 1997-04-01 Pfizer Substituted hexahydroazepinones and tetrahydrobenzazepinones
CA2168131C (en) * 1993-07-26 1998-10-06 John A. Lowe, Iii Tetrahydro-1h-benzazepinones containing acid surrogates
US5453424A (en) * 1993-11-22 1995-09-26 Merck & Co., Inc. Furanodiazepines
JPH09505597A (en) * 1993-11-22 1997-06-03 メルク エンド カンパニー インコーポレーテッド 3-acylaminobenzazepines
US5977355A (en) * 1994-10-04 1999-11-02 Pfizer Inc. Processes and intermediates for preparing 3-amino-benzo(b)azepinones
JPH10511928A (en) 1994-10-14 1998-11-17 グラクソ、ウェルカム、ソシエタ、ペル、アツィオーニ Use of a CCK-B receptor antagonist for the treatment of sleep disorders
DE10153348A1 (en) * 2001-10-29 2003-05-08 Gruenenthal Gmbh Substituted benzo (b) azepin-2-one compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166357A3 (en) * 1984-06-26 1988-10-26 Merck & Co. Inc. Benzofused lactams and pharmaceutical compositions containing them
US4767756A (en) * 1987-07-17 1988-08-30 E. R. Squibb & Sons, Inc. 3-substituted benzazepines
EP0322779A3 (en) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolactam compounds and pharmaceutical uses thereof
US5206234A (en) * 1990-10-22 1993-04-27 Merck & Co., Inc. Benzolactam analogs as antagonists of cck

Also Published As

Publication number Publication date
JPH07503465A (en) 1995-04-13
YU4393A (en) 1996-01-09
EP0625145A1 (en) 1994-11-23
CN1074903A (en) 1993-08-04
NO942775L (en) 1994-09-20
MX9300409A (en) 1993-07-01
RU94038063A (en) 1996-05-27
FI943513A (en) 1994-07-26
HUT70496A (en) 1995-10-30
ZA93582B (en) 1994-07-27
HU9402195D0 (en) 1994-09-28
CZ391092A3 (en) 1994-01-19
KR950700257A (en) 1995-01-16
IL104472A0 (en) 1993-05-13
AU3276193A (en) 1993-09-01
BR9207071A (en) 1995-12-05
TW213901B (en) 1993-10-01
CA2117367A1 (en) 1993-08-05
NO942775D0 (en) 1994-07-26
WO1993015059A1 (en) 1993-08-05
NZ245759A (en) 1997-06-24

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