ES2138070T3 - Proceso para la preparacion de formas farmaceuticas de liberacion controlada y las formas obtenidas de esta manera. - Google Patents

Proceso para la preparacion de formas farmaceuticas de liberacion controlada y las formas obtenidas de esta manera.

Info

Publication number
ES2138070T3
ES2138070T3 ES94906994T ES94906994T ES2138070T3 ES 2138070 T3 ES2138070 T3 ES 2138070T3 ES 94906994 T ES94906994 T ES 94906994T ES 94906994 T ES94906994 T ES 94906994T ES 2138070 T3 ES2138070 T3 ES 2138070T3
Authority
ES
Spain
Prior art keywords
pct
forms
excipients
sec
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94906994T
Other languages
English (en)
Inventor
Giuseppe Motta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Saitec SRL
Original Assignee
Saitec SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT92BO455 external-priority patent/IT1260242B/it
Priority claimed from ITBO930294A external-priority patent/IT1263445B/it
Priority claimed from IT93BO000460A external-priority patent/IT1268454B1/it
Application filed by Saitec SRL filed Critical Saitec SRL
Application granted granted Critical
Publication of ES2138070T3 publication Critical patent/ES2138070T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTA UN PROCESO MEJORADO PARA PREPARAR FORMAS FARMACEUTICAS DE LIBERACION CONTROLADA QUE COMPRENDE LA EXPOSICION DE UNA MEZCLA QUE COMPRENDE UNO O MAS EXCIPIENTES Y UNO O MAS INGREDIENTES ACTIVOS COMPATIBLES ENTRE SI Y CON DICHOS EXCIPIENTES A ACCIONES MECANICAS O ELECTROMECANICAS DURANTE UN PERIODO DE TIEMPO BIEN ESTABLECIDO Y DENTRO DE UNA AMPLIA GAMA DE FRECUENCIAS PARA DAR COMO RESULTADO TABLETAS, MATRICES O PELICULAS MONO O MULTIESTRATIFICADAS. DICHAS FORMAS PUEDEN ROMPERSE OPCIONALMENTE PARA DAR COMO RESULTADO UN GRANULADO O UN POLVO. DEPENDIENDO DEL EXCIPIENTE EMPLEADO, PUEDE OBTENERSE UNA LIBERACION RETARDADA O RAPIDA, PERO SIEMPRE CONTROLADA, DEL INGREDIENTE ACTIVO.
ES94906994T 1992-12-23 1993-12-23 Proceso para la preparacion de formas farmaceuticas de liberacion controlada y las formas obtenidas de esta manera. Expired - Lifetime ES2138070T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT92BO455 IT1260242B (it) 1992-12-23 1992-12-23 Procedimento per preparare forme farmaceutiche a rilascio controllato ritardato del principio attivo e le forme farmaceutiche cosi' ottenute.
ITBO930294A IT1263445B (it) 1993-06-24 1993-06-24 Procedimento per preparare forme farmaceutiche a rilascio controllato/ritardato del principio attivo e le forme farmaceutiche cosi' ottenute
IT93BO000460A IT1268454B1 (it) 1993-11-12 1993-11-12 Procedimento per preparare forme farmaceutiche a rilascio controllato del principio attivo e le forme farmaceutiche cosi' ottenute.
PCT/IT1993/000136 WO1994014421A2 (en) 1992-12-23 1993-12-23 Process for preparing controlled release pharmaceutical forms and the forms thus obtained

Publications (1)

Publication Number Publication Date
ES2138070T3 true ES2138070T3 (es) 2000-01-01

Family

ID=27273889

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94906994T Expired - Lifetime ES2138070T3 (es) 1992-12-23 1993-12-23 Proceso para la preparacion de formas farmaceuticas de liberacion controlada y las formas obtenidas de esta manera.

Country Status (14)

Country Link
US (1) US5662935A (es)
EP (1) EP0675710B1 (es)
JP (1) JP3459421B2 (es)
KR (1) KR100297541B1 (es)
AT (1) ATE183641T1 (es)
AU (1) AU683044B2 (es)
BR (1) BR9307736A (es)
CA (1) CA2151396C (es)
DE (1) DE69326163T2 (es)
DK (1) DK0675710T3 (es)
ES (1) ES2138070T3 (es)
GR (1) GR3031936T3 (es)
RU (1) RU2128499C1 (es)
WO (1) WO1994014421A2 (es)

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JP2005298338A (ja) * 2002-02-27 2005-10-27 Eisai Co Ltd 速崩壊性圧縮成形製剤
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
DE10315640A1 (de) * 2003-04-04 2004-10-14 Ignatov, Konstantin Verfahren zur kontrollierten Freisetzung von Komponenten in eine Lösung
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
US8075872B2 (en) 2003-08-06 2011-12-13 Gruenenthal Gmbh Abuse-proofed dosage form
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
WO2005049306A1 (en) * 2003-11-18 2005-06-02 Eurand Pharmaceuticals Limited Ultrasound-assisted compaction process with a compaction device made of coupled plastic-metal materials
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102005024171A1 (de) * 2005-03-22 2006-09-28 Grünenthal GmbH Verfahren und Vorrichtung zur Ultraschallverpressung einer Tablette oder einer multipartikulären Arzneiform
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
EP2131816A1 (en) * 2007-03-08 2009-12-16 Smithkline Beecham Corporation Pharmaceutical analysis apparatus and method
RU2351352C2 (ru) * 2007-04-09 2009-04-10 Закрытое акционерное общество "Санкт-Петербургский институт фармации" Твердая нанокомпозиция для доставки биологически активных веществ
WO2009092601A1 (en) 2008-01-25 2009-07-30 Grünenthal GmbH Pharmaceutical dosage form
CN102123701B (zh) 2008-05-09 2013-03-27 格吕伦塔尔有限公司 使用喷雾冻凝步骤制备中间粉末制剂以及最终固体剂型的方法
TWI473610B (zh) * 2008-10-28 2015-02-21 Twi Biotechnology Inc 包含雙醋瑞因（ｄｉａｃｅｒｅｉｎ）之醫藥組合物
PE20121067A1 (es) 2009-07-22 2012-09-05 Gruenenthal Chemie Forma de dosificacion de liberacion controlada extruida por fusion en caliente
PL2456424T3 (pl) 2009-07-22 2013-12-31 Gruenenthal Gmbh Stabilizowana przed utlenianiem odporna na naruszenie postać dawkowania
NZ608865A (en) 2010-09-02 2015-03-27 Gruenenthal Chemie Tamper resistant dosage form comprising an anionic polymer
BR112013005194A2 (pt) 2010-09-02 2016-05-03 Gruenenthal Gmbh forma de dosagem resistente à violação compreendendo sal inorgânico
EA201400172A1 (ru) 2011-07-29 2014-06-30 Грюненталь Гмбх Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства
DK2736497T3 (da) 2011-07-29 2017-11-13 Gruenenthal Gmbh Stød-resistent tablet, der tilvejebringer en øjeblikkelig frigivelse af et lægemiddel.
JP6117249B2 (ja) 2012-02-28 2017-04-19 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 薬理学的に活性な化合物および陰イオン性ポリマーを含むタンパーレジスタント剤形
TR201815502T4 (tr) 2012-04-18 2018-11-21 Gruenenthal Gmbh Kurcalama veya dirençli ve doz boşalımına dirençli farmasötik dozaj formu.
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
CA2913209A1 (en) 2013-05-29 2014-12-04 Grunenthal Gmbh Tamper resistant dosage form with bimodal release profile
WO2014191397A1 (en) 2013-05-29 2014-12-04 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
WO2015004245A1 (en) 2013-07-12 2015-01-15 Grünenthal GmbH Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
CN105555847B (zh) 2013-09-19 2018-08-10 微仙美国有限公司 聚合物膜
US9546236B2 (en) 2013-09-19 2017-01-17 Terumo Corporation Polymer particles
CN105916495B (zh) 2013-11-08 2019-11-12 泰尔茂株式会社 聚合物颗粒
MX371372B (es) 2013-11-26 2020-01-28 Gruenenthal Gmbh Preparacion de una composicion farmaceutica en polvo por medio de criomolienda.
CA2947786A1 (en) 2014-05-12 2015-11-19 Grunenthal Gmbh Tamper resistant immediate release capsule formulation comprising tapentadol
CA2949422A1 (en) 2014-05-26 2015-12-03 Grunenthal Gmbh Multiparticles safeguarded against ethanolic dose-dumping
US9907880B2 (en) 2015-03-26 2018-03-06 Microvention, Inc. Particles
CN107889459A (zh) 2015-04-24 2018-04-06 格吕伦塔尔有限公司 具有立即释放和对溶剂萃取的抗性的抗篡改剂型
WO2017042325A1 (en) 2015-09-10 2017-03-16 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
CA3038719C (en) 2016-09-28 2020-04-21 Terumo Corporation Polymer particles

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Also Published As

Publication number Publication date
RU2128499C1 (ru) 1999-04-10
JPH08504807A (ja) 1996-05-28
GR3031936T3 (en) 2000-03-31
CA2151396C (en) 2006-08-22
AU6043494A (en) 1994-07-19
ATE183641T1 (de) 1999-09-15
WO1994014421A2 (en) 1994-07-07
US5662935A (en) 1997-09-02
AU683044B2 (en) 1997-10-30
DK0675710T3 (da) 2000-03-27
EP0675710B1 (en) 1999-08-25
DE69326163T2 (de) 2000-05-04
KR960700043A (ko) 1996-01-19
EP0675710A1 (en) 1995-10-11
KR100297541B1 (ko) 2001-11-26
WO1994014421A3 (en) 1994-08-18
BR9307736A (pt) 1999-08-31
CA2151396A1 (en) 1994-07-07
JP3459421B2 (ja) 2003-10-20
DE69326163D1 (de) 1999-09-30

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