ES2042727T3 - Acidos 1,3,4,9-tetrahidropirano(3,4-b)indol-1-acetico. - Google Patents

Acidos 1,3,4,9-tetrahidropirano(3,4-b)indol-1-acetico.

Info

Publication number
ES2042727T3
ES2042727T3 ES88300820T ES88300820T ES2042727T3 ES 2042727 T3 ES2042727 T3 ES 2042727T3 ES 88300820 T ES88300820 T ES 88300820T ES 88300820 T ES88300820 T ES 88300820T ES 2042727 T3 ES2042727 T3 ES 2042727T3
Authority
ES
Spain
Prior art keywords
tetrahydropyran
indol
acetic acids
halogen
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88300820T
Other languages
English (en)
Inventor
Brian Alexander Mckittrick
Alan Howard Katz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Application granted granted Critical
Publication of ES2042727T3 publication Critical patent/ES2042727T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

DERIVADOS DE INDOL DE FORMULA (I), DONDE R1 ES HALOGENO O ALQUILO INFERIOR, Y R2 ES HIDROGENO O ALQUILO INFERIOR, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES SON UTILES COMO AGENTES ANTIINFLAMATORIOS Y ANALGESICOS. TAMBIEN SE DESCRIBEN METODOS PARA SU OBTENCION.
ES88300820T 1987-02-20 1988-02-01 Acidos 1,3,4,9-tetrahidropirano(3,4-b)indol-1-acetico. Expired - Lifetime ES2042727T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000530253A CA1319695C (en) 1987-02-20 1987-02-20 Substituted 1,3,4,9-tetrahydropyrano¬3,4-b|- indole-1-acetic acids

Publications (1)

Publication Number Publication Date
ES2042727T3 true ES2042727T3 (es) 1993-12-16

Family

ID=4135020

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88300820T Expired - Lifetime ES2042727T3 (es) 1987-02-20 1988-02-01 Acidos 1,3,4,9-tetrahidropirano(3,4-b)indol-1-acetico.

Country Status (8)

Country Link
US (2) US4785015A (es)
EP (1) EP0279548B1 (es)
JP (1) JP2733490B2 (es)
AT (1) ATE79625T1 (es)
CA (1) CA1319695C (es)
DE (1) DE3873786T2 (es)
ES (1) ES2042727T3 (es)
GR (1) GR3006108T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822781A (en) * 1987-10-08 1989-04-18 American Home Products Substituted-8-alkenyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids
TW200400963A (en) 2002-05-21 2004-01-16 Wyeth Corp R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease
TW200400818A (en) 2002-05-21 2004-01-16 Wyeth Corp Method for the use of pyranoindole derivatives to treat infection with hepatitis C virus
MX2007002837A (es) * 2004-09-10 2007-04-30 Wyeth Corp Procedimiento para la sintesis escalable de derivados de 1,3,4,9-tetrahidropirano[3,4-b]-indol.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3939178A (en) * 1971-06-01 1976-02-17 American Home Products Corporation Certain pyrano [3,4-b]indoles and thiopyrano[3,4-b]indoles
NZ219403A (en) * 1986-03-11 1989-11-28 American Home Prod 1,3,4,9-tetrahydropyrano(3,4-b indole-1-acetic acid derivatives and pharmaceutical compositions
US4686213A (en) * 1986-08-15 1987-08-11 American Home Products Corporation Substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids

Also Published As

Publication number Publication date
GR3006108T3 (es) 1993-06-21
JP2733490B2 (ja) 1998-03-30
ATE79625T1 (de) 1992-09-15
CA1319695C (en) 1993-06-29
DE3873786D1 (de) 1992-09-24
EP0279548A1 (en) 1988-08-24
JPS63208588A (ja) 1988-08-30
US4785015A (en) 1988-11-15
EP0279548B1 (en) 1992-08-19
DE3873786T2 (de) 1993-01-21
US4904799A (en) 1990-02-27

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