EP3920909A4 - Pharmaceutical compositions comprising meloxicam - Google Patents

Pharmaceutical compositions comprising meloxicam Download PDF

Info

Publication number
EP3920909A4
EP3920909A4 EP20752178.2A EP20752178A EP3920909A4 EP 3920909 A4 EP3920909 A4 EP 3920909A4 EP 20752178 A EP20752178 A EP 20752178A EP 3920909 A4 EP3920909 A4 EP 3920909A4
Authority
EP
European Patent Office
Prior art keywords
meloxicam
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20752178.2A
Other languages
German (de)
French (fr)
Other versions
EP3920909A1 (en
Inventor
Herriot TABUTEAU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axsome Therapeutics Inc
Original Assignee
Axsome Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axsome Therapeutics Inc filed Critical Axsome Therapeutics Inc
Publication of EP3920909A1 publication Critical patent/EP3920909A1/en
Publication of EP3920909A4 publication Critical patent/EP3920909A4/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
EP20752178.2A 2019-02-06 2020-02-06 Pharmaceutical compositions comprising meloxicam Pending EP3920909A4 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962802198P 2019-02-06 2019-02-06
US201962803756P 2019-02-11 2019-02-11
US201962835613P 2019-04-18 2019-04-18
US201962846311P 2019-05-10 2019-05-10
US201962860705P 2019-06-12 2019-06-12
US201962895956P 2019-09-04 2019-09-04
US201962895933P 2019-09-04 2019-09-04
US201962955905P 2019-12-31 2019-12-31
PCT/US2020/017046 WO2020163620A1 (en) 2019-02-06 2020-02-06 Pharmaceutical compositions comprising meloxicam

Publications (2)

Publication Number Publication Date
EP3920909A1 EP3920909A1 (en) 2021-12-15
EP3920909A4 true EP3920909A4 (en) 2022-11-30

Family

ID=71947112

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20752178.2A Pending EP3920909A4 (en) 2019-02-06 2020-02-06 Pharmaceutical compositions comprising meloxicam

Country Status (17)

Country Link
EP (1) EP3920909A4 (en)
JP (3) JP7237386B2 (en)
KR (1) KR20210118880A (en)
CN (1) CN113423397A (en)
AU (2) AU2020218253B2 (en)
BR (1) BR112021015467A2 (en)
CA (2) CA3213549A1 (en)
CL (1) CL2021002070A1 (en)
CO (1) CO2021010380A2 (en)
CR (1) CR20210420A (en)
EC (1) ECSP21060962A (en)
IL (1) IL285389A (en)
MA (1) MA54904A (en)
MX (1) MX2021009435A (en)
PE (1) PE20212157A1 (en)
SG (1) SG11202107926XA (en)
WO (1) WO2020163620A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024502041A (en) * 2020-12-31 2024-01-17 アクスサム セラピューティクス インコーポレイテッド Pharmaceutical compositions containing meloxicam

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040214861A1 (en) * 2003-03-28 2004-10-28 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitors and 5-HT1B1D antagonists for the treatment and prevention of migraine
US20090068262A1 (en) * 2007-04-04 2009-03-12 Ilan Zalit Rapid dissolution of combination products
US9821075B2 (en) * 2015-02-10 2017-11-21 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US20180280306A1 (en) * 2017-01-04 2018-10-04 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1126841B1 (en) * 1998-11-02 2004-12-15 Merck & Co., Inc. Combinations of a 5ht1b/1d agonist and a selective cox-2 inhibitor for the treatment of migraine
US8268791B2 (en) * 2004-08-25 2012-09-18 Aegis Therapeutics, Llc. Alkylglycoside compositions for drug administration
ES2769949T3 (en) * 2009-05-13 2020-06-29 Cydex Pharmaceuticals Inc Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of preparing and using them
AU2016218992C1 (en) * 2015-02-10 2019-09-26 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
SI3256138T1 (en) * 2015-11-25 2022-07-29 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
CN109952314A (en) * 2016-09-23 2019-06-28 泰瓦制药国际有限公司 Treat intractable migraine
PT3565550T (en) * 2017-01-04 2021-01-20 Axsome Therapeutics Inc Pharmaceutical compositions comprising meloxicam
CN110612103B (en) * 2017-05-10 2023-08-22 艾克萨姆治疗公司 Pharmaceutical composition comprising meloxicam

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040214861A1 (en) * 2003-03-28 2004-10-28 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitors and 5-HT1B1D antagonists for the treatment and prevention of migraine
US20090068262A1 (en) * 2007-04-04 2009-03-12 Ilan Zalit Rapid dissolution of combination products
US9821075B2 (en) * 2015-02-10 2017-11-21 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam
US20180280306A1 (en) * 2017-01-04 2018-10-04 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising meloxicam

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "Axosome Therapeutics announces AXS-07 for the treatment of migraine", PIPELINEREVIEW.COM, 28 November 2017 (2017-11-28), pages 1 - 2, XP055890967, Retrieved from the Internet <URL:https://pipelinereview.com/index.php/2017112866624/Small-Molecules/Axsome-Therapeutics-Announces-AXS-07-for-the-Treatment-of-Migraine.html> [retrieved on 20220214] *

Also Published As

Publication number Publication date
MX2021009435A (en) 2021-09-10
MA54904A (en) 2021-12-15
WO2020163620A1 (en) 2020-08-13
ECSP21060962A (en) 2021-11-30
CO2021010380A2 (en) 2021-09-30
EP3920909A1 (en) 2021-12-15
JP2023062144A (en) 2023-05-02
JP2022519670A (en) 2022-03-24
AU2020218253A1 (en) 2021-08-12
CA3128940A1 (en) 2020-08-13
SG11202107926XA (en) 2021-08-30
CR20210420A (en) 2021-12-22
JP2024026732A (en) 2024-02-28
AU2020218253B2 (en) 2023-02-23
JP7237386B2 (en) 2023-03-13
IL285389A (en) 2021-09-30
CN113423397A (en) 2021-09-21
BR112021015467A2 (en) 2021-10-05
JP7420990B2 (en) 2024-01-23
AU2023202545A1 (en) 2023-05-18
CA3128940C (en) 2023-11-07
PE20212157A1 (en) 2021-11-09
KR20210118880A (en) 2021-10-01
CL2021002070A1 (en) 2022-04-01
CA3213549A1 (en) 2020-08-13

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