EP3890748A4 - Zusammensetzungen und verfahren zur behandlung von lebererkrankungen - Google Patents
Zusammensetzungen und verfahren zur behandlung von lebererkrankungen Download PDFInfo
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- EP3890748A4 EP3890748A4 EP19893549.6A EP19893549A EP3890748A4 EP 3890748 A4 EP3890748 A4 EP 3890748A4 EP 19893549 A EP19893549 A EP 19893549A EP 3890748 A4 EP3890748 A4 EP 3890748A4
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- liver disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A61K31/404—Indoles, e.g. pindolol
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PCT/US2019/064548 WO2020117987A1 (en) | 2018-12-05 | 2019-12-04 | Compositions and methods for the treatment of liver disorders |
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CA (1) | CA3121620A1 (de) |
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CA2606499C (en) | 2005-05-26 | 2017-06-13 | Metabasis Therapeutics, Inc. | Thyromimetics for the treatment of fatty liver diseases |
KR20190104524A (ko) | 2016-11-21 | 2019-09-10 | 바이킹 테라퓨틱스 인코포레이티드 | 당원축적질환의 치료 방법 |
KR102600115B1 (ko) | 2017-06-05 | 2023-11-09 | 바이킹 테라퓨틱스 인코포레이티드 | 섬유증 치료를 위한 조성물 |
EP3768690A4 (de) | 2018-03-22 | 2021-11-24 | Viking Therapeutics, Inc. | Kristalline formen und verfahren zur herstellung kristalliner formen einer verbindung |
CN112707892A (zh) * | 2019-10-24 | 2021-04-27 | 苏州泽璟生物制药股份有限公司 | 哒嗪酮或哒嗪类化合物及其衍生物和药物组合物 |
US11752161B2 (en) | 2020-03-27 | 2023-09-12 | Gannex Pharma Co., Ltd. | Pharmaceutical compositions, method of making and method of using thereof |
US20230226038A1 (en) * | 2020-06-09 | 2023-07-20 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of liver disorders |
WO2021259309A1 (zh) * | 2020-06-24 | 2021-12-30 | 广州市恒诺康医药科技有限公司 | Glp-1受体激动剂及其药物组合物和用途 |
CN111793066B (zh) * | 2020-07-17 | 2022-04-08 | 瀚海新拓(杭州)生物医药有限公司 | 苯并五元杂环磺酰胺类化合物、其制备方法、药物组合物及应用 |
WO2023169456A1 (en) | 2022-03-09 | 2023-09-14 | Gasherbrum Bio , Inc. | Heterocyclic glp-1 agonists |
WO2023198140A1 (en) | 2022-04-14 | 2023-10-19 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
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CA2606499C (en) * | 2005-05-26 | 2017-06-13 | Metabasis Therapeutics, Inc. | Thyromimetics for the treatment of fatty liver diseases |
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WO2010125565A2 (en) * | 2009-04-27 | 2010-11-04 | Hadasit Medical Research Services And Development Ltd. | Anti-lps enriched immunoglobulin preparation for use in treatment and/or prophylaxis of a pathologic disorder |
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KR20210099612A (ko) | 2021-08-12 |
MX2021006575A (es) | 2021-08-16 |
JP2022510690A (ja) | 2022-01-27 |
CA3121620A1 (en) | 2020-06-11 |
EP3890748A1 (de) | 2021-10-13 |
CN113365637A (zh) | 2021-09-07 |
BR112021010916A2 (pt) | 2021-08-24 |
US20220016136A1 (en) | 2022-01-20 |
WO2020117987A1 (en) | 2020-06-11 |
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