EP3122333A4 - Cell free compositions for cellular restoration and methods of making and using same - Google Patents

Cell free compositions for cellular restoration and methods of making and using same Download PDF

Info

Publication number
EP3122333A4
EP3122333A4 EP15768892.0A EP15768892A EP3122333A4 EP 3122333 A4 EP3122333 A4 EP 3122333A4 EP 15768892 A EP15768892 A EP 15768892A EP 3122333 A4 EP3122333 A4 EP 3122333A4
Authority
EP
European Patent Office
Prior art keywords
making
methods
same
cell free
free compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP15768892.0A
Other languages
German (de)
French (fr)
Other versions
EP3122333A1 (en
Inventor
Steve Greco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Advanced Regen Medical Technologies LLC
Original Assignee
Advanced Regen Medical Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/577,978 external-priority patent/US20150174166A1/en
Application filed by Advanced Regen Medical Technologies LLC filed Critical Advanced Regen Medical Technologies LLC
Publication of EP3122333A1 publication Critical patent/EP3122333A1/en
Publication of EP3122333A4 publication Critical patent/EP3122333A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP15768892.0A 2014-03-24 2015-03-24 Cell free compositions for cellular restoration and methods of making and using same Pending EP3122333A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201461969694P 2014-03-24 2014-03-24
US14/577,978 US20150174166A1 (en) 2013-12-20 2014-12-19 Compositions for Cellular Restoration and Methods of Making and Using Same
PCT/US2014/071667 WO2015095794A1 (en) 2013-12-20 2014-12-19 Compositions for cellular restoration and methods of making and using same
PCT/US2015/022285 WO2015148534A1 (en) 2014-03-24 2015-03-24 Cell free compositions for cellular restoration and methods of making and using same

Publications (2)

Publication Number Publication Date
EP3122333A1 EP3122333A1 (en) 2017-02-01
EP3122333A4 true EP3122333A4 (en) 2017-11-29

Family

ID=54196315

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15768892.0A Pending EP3122333A4 (en) 2014-03-24 2015-03-24 Cell free compositions for cellular restoration and methods of making and using same

Country Status (4)

Country Link
EP (1) EP3122333A4 (en)
JP (2) JP6471302B2 (en)
CR (1) CR20160495A (en)
WO (1) WO2015148534A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11286463B2 (en) 2012-03-08 2022-03-29 Advanced ReGen Medical Technologies, LLC Reprogramming of aged adult stem cells
US10772911B2 (en) 2013-12-20 2020-09-15 Advanced ReGen Medical Technologies, LLC Cell free compositions for cellular restoration and methods of making and using same
JP6353073B2 (en) 2013-12-20 2018-07-04 アドヴァンスド リジェン メディカル テクノロジーズ，エルエルシー Composition for cell recovery and method for producing and using the same
CA3023468A1 (en) 2016-04-29 2017-11-02 Advanced ReGen Medical Technologies, LLC Microrna compositions and methods of making and using same
WO2019143847A1 (en) 2018-01-18 2019-07-25 Advanced ReGen Medical Technologies, LLC Therapeutic compositions and methods of making and using the same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014028493A2 (en) * 2012-08-13 2014-02-20 Cedars-Sinai Medical Center Exosomes and micro-ribonucleic acids for tissue regeneration

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1766053A4 (en) * 2004-06-02 2007-12-12 Sourcepharm Inc Rna-containing microvesicles and methods therefor
WO2010150783A1 (en) * 2009-06-25 2010-12-29 株式会社 日立メディコ Medical imaging apparatus
EP2363136A1 (en) * 2010-03-02 2011-09-07 Fresenius Medical Care Deutschland GmbH Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease
US20120093885A1 (en) * 2010-10-18 2012-04-19 Northwestern University Therapeutic vesicles
WO2013066368A1 (en) * 2011-10-03 2013-05-10 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Use of mirna 126 to produce hematopoietic stem cells
US9427450B2 (en) * 2012-01-31 2016-08-30 Xon Cells, Inc. Therapeutic immune modulation by stem cell secreted exosomes
US9295696B2 (en) * 2012-06-08 2016-03-29 University of Pittsburgh—of the Commonwealth System of Higher Education Compositions and methods for restoring or rejuvenating stem/progenitor cell function

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014028493A2 (en) * 2012-08-13 2014-02-20 Cedars-Sinai Medical Center Exosomes and micro-ribonucleic acids for tissue regeneration

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BO YU ET AL: "Exosomes Derived from Mesenchymal Stem Cells", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 15, no. 3, 7 March 2014 (2014-03-07), pages 4142 - 4157, XP055407121, DOI: 10.3390/ijms15034142 *
DIANA M. IGLESIAS ET AL: "Stem Cell Microvesicles Transfer Cystinosin to Human Cystinotic Cells and Reduce Cystine Accumulation In Vitro", PLOS ONE, vol. 7, no. 8, 13 August 2012 (2012-08-13), pages e42840, XP055408200, DOI: 10.1371/journal.pone.0042840 *
L KORDELAS ET AL: "MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease", LEUKEMIA., 21 January 2014 (2014-01-21), US, XP055406936, ISSN: 0887-6924, DOI: 10.1038/leu.2014.41 *
See also references of WO2015148534A1 *
SERENA RUBINA BAGLIO ET AL: "Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy", FRONTIERS IN PHYSIOLOGY, vol. 3, 1 January 2012 (2012-01-01), XP055406899, DOI: 10.3389/fphys.2012.00359 *

Also Published As

Publication number Publication date
WO2015148534A1 (en) 2015-10-01
JP6900358B2 (en) 2021-07-07
JP6471302B2 (en) 2019-02-20
JP2017510582A (en) 2017-04-13
CR20160495A (en) 2017-05-29
EP3122333A1 (en) 2017-02-01
JP2019052182A (en) 2019-04-04

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