EP3060216A4 - Methods for treating hcv - Google Patents

Methods for treating hcv Download PDF

Info

Publication number
EP3060216A4
EP3060216A4 EP14856676.3A EP14856676A EP3060216A4 EP 3060216 A4 EP3060216 A4 EP 3060216A4 EP 14856676 A EP14856676 A EP 14856676A EP 3060216 A4 EP3060216 A4 EP 3060216A4
Authority
EP
European Patent Office
Prior art keywords
methods
treating hcv
hcv
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14856676.3A
Other languages
German (de)
French (fr)
Other versions
EP3060216A2 (en
Inventor
Iok Chan Ng
Liangjun Lu
Tanya DEKHTYAR
Thomas Reisch
Rakesh L. Tripathi
Ron PITHAWALLA
Christine A. Collins
Tami J. Pilot-Matias
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Inc
Original Assignee
AbbVie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AbbVie Inc filed Critical AbbVie Inc
Publication of EP3060216A2 publication Critical patent/EP3060216A2/en
Publication of EP3060216A4 publication Critical patent/EP3060216A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP14856676.3A 2013-10-25 2014-10-24 Methods for treating hcv Withdrawn EP3060216A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361895945P 2013-10-25 2013-10-25
PCT/US2014/062265 WO2015061742A2 (en) 2013-10-25 2014-10-24 Methods for treating hcv

Publications (2)

Publication Number Publication Date
EP3060216A2 EP3060216A2 (en) 2016-08-31
EP3060216A4 true EP3060216A4 (en) 2017-06-21

Family

ID=52993758

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14856676.3A Withdrawn EP3060216A4 (en) 2013-10-25 2014-10-24 Methods for treating hcv

Country Status (7)

Country Link
US (1) US20150119400A1 (en)
EP (1) EP3060216A4 (en)
JP (1) JP2016534082A (en)
CN (1) CN105658219A (en)
CA (1) CA2925328A1 (en)
MX (1) MX2016005393A (en)
WO (1) WO2015061742A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11484534B2 (en) 2013-03-14 2022-11-01 Abbvie Inc. Methods for treating HCV
CN110302361A (en) 2014-04-02 2019-10-08 艾伯维公司 The method for treating HCV
MX2016016127A (en) * 2014-06-06 2017-02-23 Abbvie Inc Crystal forms.
US20160375017A1 (en) 2015-06-26 2016-12-29 Abbvie Inc. Solid Pharmaceutical Compositions for Treating HCV
AU2016291154B2 (en) * 2015-07-08 2021-10-21 Abbvie Inc. Methods for treating HCV
TW202322824A (en) 2020-02-18 2023-06-16 美商基利科學股份有限公司 Antiviral compounds
CA3216162A1 (en) 2021-04-16 2022-10-20 Gilead Sciences, Inc. Methods of preparing carbanucleosides using amides

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120070416A1 (en) * 2010-09-21 2012-03-22 Enanta Pharmaceuticals, Inc. Macrocyclic Proline Derived HCV Serine Protease Inhibitors
WO2014152635A1 (en) * 2013-03-14 2014-09-25 Abbvie Inc. Combination of direct acting antiviral agents and ribavirin for treating hcv patients
WO2014152514A1 (en) * 2013-03-14 2014-09-25 Abbvie Inc. Combination of two antivirals for treating hepatitis c

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120070416A1 (en) * 2010-09-21 2012-03-22 Enanta Pharmaceuticals, Inc. Macrocyclic Proline Derived HCV Serine Protease Inhibitors
WO2014152635A1 (en) * 2013-03-14 2014-09-25 Abbvie Inc. Combination of direct acting antiviral agents and ribavirin for treating hcv patients
WO2014152514A1 (en) * 2013-03-14 2014-09-25 Abbvie Inc. Combination of two antivirals for treating hepatitis c

Also Published As

Publication number Publication date
US20150119400A1 (en) 2015-04-30
CN105658219A (en) 2016-06-08
MX2016005393A (en) 2016-08-11
EP3060216A2 (en) 2016-08-31
JP2016534082A (en) 2016-11-04
CA2925328A1 (en) 2015-04-30
WO2015061742A2 (en) 2015-04-30

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20160511

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Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20170524

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/7056 20060101ALI20170518BHEP

Ipc: A61K 31/53 20060101ALI20170518BHEP

Ipc: A61K 31/498 20060101AFI20170518BHEP

Ipc: A61K 45/06 20060101ALI20170518BHEP

Ipc: A61K 31/12 20060101ALI20170518BHEP

Ipc: A61P 31/14 20060101ALI20170518BHEP

Ipc: A61K 31/00 20060101ALI20170518BHEP

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Effective date: 20171223