EP2872652A4 - Devices and methods for nucleic acid preparation and analysis - Google Patents

Devices and methods for nucleic acid preparation and analysis

Info

Publication number
EP2872652A4
EP2872652A4 EP13778675.2A EP13778675A EP2872652A4 EP 2872652 A4 EP2872652 A4 EP 2872652A4 EP 13778675 A EP13778675 A EP 13778675A EP 2872652 A4 EP2872652 A4 EP 2872652A4
Authority
EP
European Patent Office
Prior art keywords
analysis
methods
devices
nucleic acid
acid preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13778675.2A
Other languages
German (de)
French (fr)
Other versions
EP2872652A1 (en
Inventor
John L Harris
Adrian Mark Thomas West
Broeck Dirk Peter Ten
Ekaterina Protozanova
Robert H Meltzer
Joshua W Griffis
Rudolf Gilmanshin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PathoGenetix Inc
Original Assignee
PathoGenetix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PathoGenetix Inc filed Critical PathoGenetix Inc
Publication of EP2872652A1 publication Critical patent/EP2872652A1/en
Publication of EP2872652A4 publication Critical patent/EP2872652A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0663—Stretching or orienting elongated molecules or particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP13778675.2A 2012-04-18 2013-04-18 Devices and methods for nucleic acid preparation and analysis Withdrawn EP2872652A4 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261635263P 2012-04-18 2012-04-18
US201261625743P 2012-04-18 2012-04-18
US201261635221P 2012-04-18 2012-04-18
US201261625745P 2012-04-18 2012-04-18
US201361784061P 2013-03-14 2013-03-14
US201361783601P 2013-03-14 2013-03-14
US201361784399P 2013-03-14 2013-03-14
US201361790721P 2013-03-15 2013-03-15
PCT/US2013/037140 WO2013158860A1 (en) 2012-04-18 2013-04-18 Devices and methods for nucleic acid preparation and analysis

Publications (2)

Publication Number Publication Date
EP2872652A1 EP2872652A1 (en) 2015-05-20
EP2872652A4 true EP2872652A4 (en) 2016-03-09

Family

ID=49384067

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13778675.2A Withdrawn EP2872652A4 (en) 2012-04-18 2013-04-18 Devices and methods for nucleic acid preparation and analysis

Country Status (2)

Country Link
EP (1) EP2872652A4 (en)
WO (1) WO2013158860A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018022014A1 (en) * 2016-07-26 2018-02-01 Hewlett-Packard Development Company, L.P. Microfluidic device with manifold
US20200061617A1 (en) * 2016-12-07 2020-02-27 Niagara Biosciences, Inc. Devices and methods for nucleic acid identification
CN109622072B (en) * 2019-02-28 2023-08-22 枣庄学院 Laboratory waste liquid storage and recovery device
CN111718836B (en) * 2020-06-16 2022-08-26 东南大学 Microfluidic chip for rare cell acquisition and single cell packaging
CN114682310B (en) * 2020-12-31 2023-12-05 深圳市真迈生物科技有限公司 Liquid path system, sequencing system and method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000009757A1 (en) * 1998-08-13 2000-02-24 U.S. Genomics, Inc. Optically characterizing polymers
WO2001013088A1 (en) * 1999-08-13 2001-02-22 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
WO2004091795A2 (en) * 2003-04-10 2004-10-28 U.S. Genomics, Inc. Manipulation of polymers in a microchannel

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6696022B1 (en) * 1999-08-13 2004-02-24 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
US20050142565A1 (en) * 2003-12-30 2005-06-30 Agency For Science, Technology And Research Nucleic acid purification chip
WO2006118420A1 (en) * 2005-04-30 2006-11-09 Jae Chern Yoo Bio-disc, bio-driver apparatus, and assay method using the same
WO2006122310A2 (en) * 2005-05-11 2006-11-16 The Trustess Of The University Of Pennsylvania System for testing
US8114636B2 (en) * 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids
US8841116B2 (en) * 2006-10-25 2014-09-23 The Regents Of The University Of California Inline-injection microdevice and microfabricated integrated DNA analysis system using same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000009757A1 (en) * 1998-08-13 2000-02-24 U.S. Genomics, Inc. Optically characterizing polymers
WO2001013088A1 (en) * 1999-08-13 2001-02-22 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
WO2004091795A2 (en) * 2003-04-10 2004-10-28 U.S. Genomics, Inc. Manipulation of polymers in a microchannel

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BAKAJIN O B ET AL: "ELECTROHYDRODYNAMIC STRETCHING OF DNA IN CONFINED ENVIRONMENTS", PHYSICAL REVIEW LETTERS, AMERICAN PHYSICAL SOCIETY, US, vol. 80, no. 12, 23 March 1998 (1998-03-23), pages 2737 - 2740, XP000980688, ISSN: 0031-9007, DOI: 10.1103/PHYSREVLETT.80.2737 *
CHAN E Y ET AL: "DNA mapping using microfluidic stretching and single-molecule detection of fluorescent site-specific tags", GENOME RESEARCH, COLD SPRING HARBOR LABORATORY PRESS, vol. 14, no. 6, 1 June 2004 (2004-06-01), pages 1137 - 1146, XP002346048, ISSN: 1088-9051, DOI: 10.1101/GR.1635204 *
See also references of WO2013158860A1 *

Also Published As

Publication number Publication date
WO2013158860A1 (en) 2013-10-24
EP2872652A1 (en) 2015-05-20

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Extension state: BA ME

RIN1 Information on inventor provided before grant (corrected)

Inventor name: GRIFFIS, JOSHUA, W.

Inventor name: PROTOZANOVA, EKATERINA

Inventor name: HARRIS, JOHN, L.

Inventor name: WEST, ADRIAN MARK, THOMAS

Inventor name: TEN BROECK, DIRK, PETER

Inventor name: GILMANSHIN, RUDOLF

Inventor name: MELTZER, ROBERT H.

DAX Request for extension of the european patent (deleted)
RA4 Supplementary search report drawn up and despatched (corrected)

Effective date: 20160204

RIC1 Information provided on ipc code assigned before grant

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Ipc: C12Q 1/68 20060101AFI20160129BHEP

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