EP2766087A4 - Non-regular electrical stimulation patterns for treating neurological disorders - Google Patents

Non-regular electrical stimulation patterns for treating neurological disorders

Info

Publication number
EP2766087A4
EP2766087A4 EP12839657.9A EP12839657A EP2766087A4 EP 2766087 A4 EP2766087 A4 EP 2766087A4 EP 12839657 A EP12839657 A EP 12839657A EP 2766087 A4 EP2766087 A4 EP 2766087A4
Authority
EP
European Patent Office
Prior art keywords
electrical stimulation
neurological disorders
treating neurological
stimulation patterns
regular electrical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP12839657.9A
Other languages
German (de)
French (fr)
Other versions
EP2766087A2 (en
Inventor
Warren M Grill
David T Brocker
Merill J Birdno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Priority to EP18167953.1A priority Critical patent/EP3372274B1/en
Priority to EP20175204.5A priority patent/EP3718596B1/en
Publication of EP2766087A2 publication Critical patent/EP2766087A2/en
Publication of EP2766087A4 publication Critical patent/EP2766087A4/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36178—Burst or pulse train parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0534—Electrodes for deep brain stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36189—Control systems using modulation techniques
    • A61N1/36196—Frequency modulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP12839657.9A 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders Ceased EP2766087A4 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP18167953.1A EP3372274B1 (en) 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders
EP20175204.5A EP3718596B1 (en) 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161545791P 2011-10-11 2011-10-11
US201161558871P 2011-11-11 2011-11-11
PCT/US2012/059787 WO2013055940A2 (en) 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP20175204.5A Division EP3718596B1 (en) 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders
EP18167953.1A Division EP3372274B1 (en) 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders

Publications (2)

Publication Number Publication Date
EP2766087A2 EP2766087A2 (en) 2014-08-20
EP2766087A4 true EP2766087A4 (en) 2015-05-06

Family

ID=48082746

Family Applications (3)

Application Number Title Priority Date Filing Date
EP18167953.1A Active EP3372274B1 (en) 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders
EP20175204.5A Active EP3718596B1 (en) 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders
EP12839657.9A Ceased EP2766087A4 (en) 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP18167953.1A Active EP3372274B1 (en) 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders
EP20175204.5A Active EP3718596B1 (en) 2011-10-11 2012-10-11 Non-regular electrical stimulation patterns for treating neurological disorders

Country Status (5)

Country Link
EP (3) EP3372274B1 (en)
CN (2) CN106955417B (en)
AU (4) AU2012322739A1 (en)
CA (2) CA2846639C (en)
WO (1) WO2013055940A2 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009300264B2 (en) 2008-10-03 2014-07-17 Duke University Non-regular electrical stimulation patterns for treating neurological disorders
US11013924B2 (en) 2008-10-03 2021-05-25 Duke University Non-regular electrical stimulation patterns for treating neurological disorders
US9802046B2 (en) 2008-10-03 2017-10-31 Duke University Non-regular electrical stimulation patterns for improved efficiency in treating Parkinson's Disease
US8798755B2 (en) 2008-10-03 2014-08-05 Duke University Non-regular electrical stimulation patterns for treating neurological disorders
US8923981B2 (en) 2008-10-03 2014-12-30 Duke University Non-regular electrical stimulation patterns designed with a cost function for treating neurological disorders
JP5847167B2 (en) 2010-05-27 2016-01-20 エヌディーアイ メディカル， エルエルシー Waveform shapes for neurological disorder treatment optimized for energy efficiency
US9821159B2 (en) 2010-11-16 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Stimulation devices and methods
WO2012068247A1 (en) 2010-11-16 2012-05-24 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for treatment of dry eye
EP2967817B1 (en) 2013-03-12 2021-03-10 Oculeve, Inc. Implant delivery devices and systems
US10155108B2 (en) 2013-04-19 2018-12-18 Oculeve, Inc. Nasal stimulation devices and methods
WO2014190167A2 (en) * 2013-05-22 2014-11-27 Deep Brain Innovations LLC Deep brain stimulator and method of use
US10688306B2 (en) 2013-12-23 2020-06-23 Deep Brain Innovations LLC Programming systems for deep brain stimulator system
CN106470673B (en) 2014-02-25 2020-01-31 奥库利维公司 Polymer formulations for nasolacrimal stimulation
US9687652B2 (en) 2014-07-25 2017-06-27 Oculeve, Inc. Stimulation patterns for treating dry eye
EP3209371A4 (en) 2014-10-22 2018-10-24 Oculeve, Inc. Implantable nasal stimulator systems and methods
AU2015335772B2 (en) 2014-10-22 2020-07-09 Oculeve, Inc. Contact lens for increasing tear production
WO2016065215A1 (en) 2014-10-22 2016-04-28 Oculeve, Inc. Stimulation devices and methods for treating dry eye
DE102014117429A1 (en) * 2014-11-27 2016-06-02 Forschungszentrum Jülich GmbH Apparatus and method for effective invasive neurostimulation by means of varying stimulus sequences
CN107847180A (en) * 2015-05-08 2018-03-27 杜克大学 spinal cord stimulation system and method
EP3328481B1 (en) 2015-07-30 2019-05-15 Boston Scientific Neuromodulation Corporation User interface for custom patterned electrical stimulation
US10603482B2 (en) * 2015-09-23 2020-03-31 Cala Health, Inc. Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors
WO2017066187A1 (en) 2015-10-15 2017-04-20 Boston Scientific Neuromodulation Corporation User interface for neurostimulation waveform composition
US10391313B2 (en) 2015-12-04 2019-08-27 Boston Scientific Neuromodulation Corporation Systems and methods for the development of therapy paradigms for neurological treatments
US10426958B2 (en) 2015-12-04 2019-10-01 Oculeve, Inc. Intranasal stimulation for enhanced release of ocular mucins and other tear proteins
US11344722B2 (en) 2016-01-21 2022-05-31 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US10252048B2 (en) 2016-02-19 2019-04-09 Oculeve, Inc. Nasal stimulation for rhinitis, nasal congestion, and ocular allergies
CA3022683A1 (en) 2016-05-02 2017-11-09 Oculeve, Inc. Intranasal stimulation for treatment of meibomian gland disease and blepharitis
KR20190124698A (en) 2016-12-02 2019-11-05 오큘레브, 인크. Apparatus and Method for Dry Eye Prediction and Treatment Recommendations
US11857778B2 (en) 2018-01-17 2024-01-02 Cala Health, Inc. Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation
US11890468B1 (en) 2019-10-03 2024-02-06 Cala Health, Inc. Neurostimulation systems with event pattern detection and classification
US20230064864A1 (en) * 2020-01-15 2023-03-02 Carnegie Mellon University Neuromodulation Using Electrical Stimulation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833005A (en) * 1971-07-26 1974-09-03 Medtronic Inc Compared count digitally controlled pacemaker
US5018524A (en) * 1985-05-15 1991-05-28 Hansen Gu Apparatus and method for generating vital information signals
US5095904A (en) * 1989-09-08 1992-03-17 Cochlear Pty. Ltd. Multi-peak speech procession
US20100152807A1 (en) * 2008-10-03 2010-06-17 Duke University Non-regular electrical stimulation patterns for treating neurological disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1003839B (en) * 1986-04-24 1989-04-12 顾涵森 Apparatus and method for generating vital information signal
US6366813B1 (en) * 1998-08-05 2002-04-02 Dilorenzo Daniel J. Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US7010351B2 (en) * 2000-07-13 2006-03-07 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
DE10318071A1 (en) * 2003-04-17 2004-11-25 Forschungszentrum Jülich GmbH Device for desynchronizing neuronal brain activity
WO2007080460A1 (en) * 2005-09-15 2007-07-19 Koninklijke Philips Electronics, N.V. Apparatus and method for electrostimulation/sensing in vivo

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833005A (en) * 1971-07-26 1974-09-03 Medtronic Inc Compared count digitally controlled pacemaker
US5018524A (en) * 1985-05-15 1991-05-28 Hansen Gu Apparatus and method for generating vital information signals
US5095904A (en) * 1989-09-08 1992-03-17 Cochlear Pty. Ltd. Multi-peak speech procession
US20100152807A1 (en) * 2008-10-03 2010-06-17 Duke University Non-regular electrical stimulation patterns for treating neurological disorders

Also Published As

Publication number Publication date
AU2019205970A1 (en) 2019-08-01
CA2846639C (en) 2022-10-18
CA3169207A1 (en) 2013-04-18
CN106955417A (en) 2017-07-18
WO2013055940A3 (en) 2014-05-30
CN103889503B (en) 2017-03-08
CN103889503A (en) 2014-06-25
AU2017203037A1 (en) 2017-06-01
CN106955417B (en) 2021-08-20
AU2012322739A1 (en) 2014-03-13
EP3372274A1 (en) 2018-09-12
EP2766087A2 (en) 2014-08-20
AU2021202778A1 (en) 2021-05-27
AU2017203037B2 (en) 2019-04-18
EP3718596B1 (en) 2023-06-28
AU2019205970B2 (en) 2021-02-04
EP3372274B1 (en) 2020-06-24
WO2013055940A2 (en) 2013-04-18
EP3718596A1 (en) 2020-10-07
CA2846639A1 (en) 2013-04-18

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