EP2027251A4 - Systeme de cyclage thermique - Google Patents
Systeme de cyclage thermiqueInfo
- Publication number
- EP2027251A4 EP2027251A4 EP07783905A EP07783905A EP2027251A4 EP 2027251 A4 EP2027251 A4 EP 2027251A4 EP 07783905 A EP07783905 A EP 07783905A EP 07783905 A EP07783905 A EP 07783905A EP 2027251 A4 EP2027251 A4 EP 2027251A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- thermal cycling
- cycling system
- thermal
- cycling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/168—Specific optical properties, e.g. reflective coatings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
- B01L2300/185—Means for temperature control using fluid heat transfer medium using a liquid as fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/02—Water baths; Sand baths; Air baths
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
- B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12178744.4A EP2535427A3 (fr) | 2006-05-17 | 2007-05-17 | Système de cycle thermique |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80117806P | 2006-05-17 | 2006-05-17 | |
US83249206P | 2006-07-21 | 2006-07-21 | |
US87317206P | 2006-12-06 | 2006-12-06 | |
US87308406P | 2006-12-06 | 2006-12-06 | |
PCT/US2007/069197 WO2008070198A2 (fr) | 2006-05-17 | 2007-05-17 | Système de cyclage thermique |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2027251A2 EP2027251A2 (fr) | 2009-02-25 |
EP2027251A4 true EP2027251A4 (fr) | 2010-05-05 |
Family
ID=39492885
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12178744.4A Withdrawn EP2535427A3 (fr) | 2006-05-17 | 2007-05-17 | Système de cycle thermique |
EP07783905A Ceased EP2027251A4 (fr) | 2006-05-17 | 2007-05-17 | Systeme de cyclage thermique |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12178744.4A Withdrawn EP2535427A3 (fr) | 2006-05-17 | 2007-05-17 | Système de cycle thermique |
Country Status (3)
Country | Link |
---|---|
EP (2) | EP2535427A3 (fr) |
JP (1) | JP2009537152A (fr) |
WO (1) | WO2008070198A2 (fr) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8541238B2 (en) * | 2008-09-09 | 2013-09-24 | Douglas Machine Inc. | Apparatus and methods for performing real time PCR in array tape |
WO2010088514A1 (fr) * | 2009-01-30 | 2010-08-05 | Micronics, Inc. | Système portable de détection de fluorescence à gain élevé |
CN102439130A (zh) * | 2009-03-31 | 2012-05-02 | 财团法人神奈川科学技术研究院 | 液体回流型高速基因扩增装置 |
DE212010000039U1 (de) * | 2009-04-03 | 2012-02-02 | Helixis, Inc. | Geräte zum erhitzen biologischer proben |
GB2511692A (en) * | 2009-08-08 | 2014-09-10 | Bibby Scient Ltd | An apparatus for treating a test sample |
GB2512764B (en) * | 2009-08-08 | 2014-12-24 | Bibby Scient Ltd | An apparatus for treating a test sample |
CN102471746B (zh) * | 2009-08-20 | 2013-07-10 | 宝生物工程有限公司 | 温度循环装置 |
DE202010010523U1 (de) * | 2009-09-09 | 2010-11-18 | Helixis, Inc., Carlsbad | Optisches System für Mehrfachreaktionen |
JP5343801B2 (ja) * | 2009-09-30 | 2013-11-13 | 凸版印刷株式会社 | 遺伝子処理装置用伝熱装置及び遺伝子処理装置 |
ES2363697B1 (es) * | 2009-10-26 | 2012-04-20 | Ingenia Biosystems, S.L. | Aparato para el bloqueo de los ácidos nucleicos mediante fotoactivación de agentes intercalantes. |
KR101873199B1 (ko) * | 2010-01-12 | 2018-08-03 | 아람 바이오시스템 주식회사 | 3단 열대류 장치 및 그 사용법 |
US9132423B2 (en) | 2010-01-29 | 2015-09-15 | Micronics, Inc. | Sample-to-answer microfluidic cartridge |
EP2556173B1 (fr) | 2010-04-09 | 2021-05-26 | Life Technologies Corporation | Uniformité thermique améliorée pour instrumentation de thermocycleur à l'aide de régulation dynamique |
US9170028B1 (en) | 2010-10-06 | 2015-10-27 | Lawrence Livermore National Security, Llc | Methods and compositions for rapid thermal cycling |
US9446410B2 (en) | 2010-12-03 | 2016-09-20 | Biofire Defense, Llc | Thermal cycler apparatus with elastomeric adhesive |
JP5687514B2 (ja) * | 2011-02-17 | 2015-03-18 | 株式会社日立ハイテクノロジーズ | 核酸配列解析装置 |
JP2012187054A (ja) * | 2011-03-11 | 2012-10-04 | Hitachi High-Technologies Corp | 核酸増幅反応装置 |
CA3082652A1 (fr) * | 2011-04-15 | 2012-10-18 | Becton, Dickinson And Company | Thermocycleur microfluidique en temps reel a balayage et procedes synchronises de thermocyclage et de detection optique a balayage |
JP5663541B2 (ja) * | 2012-09-19 | 2015-02-04 | 株式会社日立ハイテクノロジーズ | 反応容器,並列処理装置、及びシーケンサ |
US20140112829A1 (en) * | 2012-10-22 | 2014-04-24 | Qiagen Gaithersburg, Inc. | Tube strip handling and heating apparatus |
JP6935167B2 (ja) | 2012-12-21 | 2021-09-15 | ペルキネルマー ヘルス サイエンシーズ, インコーポレイテッド | マイクロ流体使用のための低弾性フィルム |
CN104919191B (zh) | 2012-12-21 | 2019-07-09 | 精密公司 | 流体回路及相关的制造方法 |
KR20150097764A (ko) | 2012-12-21 | 2015-08-26 | 마이크로닉스 인코포레이티드. | 휴대형 형광 검출 시스템 및 미량분석 카트리지 |
EP2994532B1 (fr) | 2013-05-07 | 2017-11-15 | Micronics, Inc. | Procédés de préparation d'échantillons d'acides nucléiques faisant appel à des minéraux argileux et à des solutions alcalines |
EP2994543B1 (fr) | 2013-05-07 | 2018-08-15 | Micronics, Inc. | Dispositif pour la préparation et l'analyse d'acides nucléiques |
WO2014182844A1 (fr) | 2013-05-07 | 2014-11-13 | Micronics, Inc. | Dispositifs microfluidiques et méthodes de séparation du sérum et de compatibilité croisée du sang |
US9352502B2 (en) | 2013-06-25 | 2016-05-31 | Lawrence Livermore National Security, Llc | Porous media heat transfer for injection molding |
JP6655539B2 (ja) | 2013-09-16 | 2020-02-26 | ライフ テクノロジーズ コーポレーション | サーモサイクラー熱均一性を提供するための器具、システム、及び方法 |
WO2015126621A1 (fr) | 2014-02-18 | 2015-08-27 | Life Technologies Corporation | Appareils, systèmes et procédés pour fournir des dispositifs à cycle thermique pouvant être mis à l'échelle et isoler des dispositifs thermoélectriques |
EP3765593A4 (fr) * | 2018-03-15 | 2022-03-23 | Kryptos Biotechnologies, Inc. | Procédé et système pour effectuer des réactions biochimiques assistées par la chaleur |
CN109030133B (zh) * | 2018-06-14 | 2021-04-30 | 华东交通大学 | 一种t型试样制作试件的方法 |
US11440015B2 (en) | 2018-08-08 | 2022-09-13 | Lawrence Livermore National Security, Llc | Integrated solid-state rapid thermo-cycling system |
CN109168298A (zh) * | 2018-10-18 | 2019-01-08 | 中国科学院合肥物质科学研究院 | 一种用于pcr检测仪温控系统的散热装置 |
KR20210099007A (ko) | 2018-11-09 | 2021-08-11 | 디그니타나 에이비 | 두피 냉각 장치, 방법 및 시스템 |
SG10201908290RA (en) * | 2019-09-09 | 2021-04-29 | Star Array Pte Ltd | Apparatus for polymerase chain reaction of nucleic acid |
DE102022109312A1 (de) | 2021-05-05 | 2022-11-10 | Frieder Weidhase | Vorrichtung zum beschleunigten, miniaturisierten Kühlen und Heizen in der Medizintechnik |
CN114854570B (zh) * | 2022-07-05 | 2022-09-02 | 鲲鹏基因(北京)科技有限责任公司 | 温控装置、液冷温控系统及pcr仪 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0363143A2 (fr) * | 1988-10-06 | 1990-04-11 | Coy Corporation | Appareil de régulation de température |
JPH07185363A (ja) * | 1993-12-27 | 1995-07-25 | Shuji Ueda | 加熱冷却器 |
US20020086417A1 (en) * | 2000-12-29 | 2002-07-04 | Shuqi Chen | Sample processing device and method |
US20030157721A1 (en) * | 1998-08-13 | 2003-08-21 | Symyx Technologies, Inc. | Parallel reactor with internal sensing and method of using same |
US20040178357A1 (en) * | 2003-02-28 | 2004-09-16 | Applera Corporation | Excitation and emission filter |
WO2004105947A2 (fr) * | 2003-05-23 | 2004-12-09 | Bio-Rad Laboratories, Inc. | Controle de temperature localise pour ensemble spatial de milieux reactionnels |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
KR100236506B1 (ko) * | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
US5440388A (en) | 1993-08-02 | 1995-08-08 | Erickson; Jon W. | Chemical analysis and imaging by discrete fourier transform spectroscopy |
US5792610A (en) | 1996-05-01 | 1998-08-11 | Biorad Laboratories, Inc. | Method for conducting multiparametric fluorescence in situ hybridization |
PT1179600E (pt) * | 1996-06-04 | 2005-08-31 | Univ Utah Res Found | Monitorizacao da hibridacao durante a rcp |
JPH10117765A (ja) * | 1996-10-18 | 1998-05-12 | Ngk Insulators Ltd | 試料容器及びその製造方法 |
US6207392B1 (en) | 1997-11-25 | 2001-03-27 | The Regents Of The University Of California | Semiconductor nanocrystal probes for biological applications and process for making and using such probes |
AU751280B2 (en) | 1997-12-12 | 2002-08-08 | Applera Corporation | Optical resonance analysis system |
US6369893B1 (en) | 1998-05-19 | 2002-04-09 | Cepheid | Multi-channel optical detection system |
GB9810350D0 (en) | 1998-05-14 | 1998-07-15 | Ciba Geigy Ag | Organic compounds |
GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
US6037130A (en) | 1998-07-28 | 2000-03-14 | The Public Health Institute Of The City Of New York, Inc. | Wavelength-shifting probes and primers and their use in assays and kits |
US6306658B1 (en) * | 1998-08-13 | 2001-10-23 | Symyx Technologies | Parallel reactor with internal sensing |
JP2000214506A (ja) | 1998-11-03 | 2000-08-04 | Toshiba Research Europe Ltd | 放射光線源及び撮像システム |
WO2000069561A1 (fr) * | 1999-05-14 | 2000-11-23 | Hitachi Chemical Research Center, Inc. | Appareil de chauffage a metal liquide pour echantillon biologique ou chimique |
DE29917313U1 (de) * | 1999-10-01 | 2001-02-15 | Mwg Biotech Ag | Vorrichtung zur Durchführung chemischer oder biologischer Reaktionen |
US6852986B1 (en) * | 1999-11-12 | 2005-02-08 | E. I. Du Pont De Nemours And Company | Fluorometer with low heat-generating light source |
US6403037B1 (en) | 2000-02-04 | 2002-06-11 | Cepheid | Reaction vessel and temperature control system |
US6783934B1 (en) | 2000-05-01 | 2004-08-31 | Cepheid, Inc. | Methods for quantitative analysis of nucleic acid amplification reaction |
JP2003024063A (ja) * | 2001-07-12 | 2003-01-28 | Toshio Kawai | Dnaの連続増幅方法とその装置 |
WO2003027673A1 (fr) * | 2001-07-31 | 2003-04-03 | Olympus Corporation | Appareil d'inspection genique et procede d'extraction d'acide nucleique cible faisant appel a cet appareil |
WO2003025540A2 (fr) | 2001-09-18 | 2003-03-27 | U.S. Genomics, Inc. | Marquage differentiel de polymeres pour une analyse lineaire a haute resolution |
US6928860B1 (en) * | 2002-02-08 | 2005-08-16 | King Refrigeration, Inc. | Heat-transfer-inhibiting motor and rotor |
JP2004028775A (ja) * | 2002-06-25 | 2004-01-29 | Olympus Corp | 遺伝子検査装置およびそれを用いた検出方法 |
US6998598B2 (en) | 2002-08-02 | 2006-02-14 | Sandia National Labroatories | Modular optical detector system |
US7113624B2 (en) | 2002-10-15 | 2006-09-26 | Palo Alto Research Center Incorporated | Imaging apparatus and method employing a large linear aperture |
KR100480637B1 (ko) | 2002-11-27 | 2005-03-31 | 삼성전자주식회사 | 고속의 프로그램 가능한 고정 우선 순위 및 라운드 로빈아비터 및 그 버스 제어 방법 |
US20050136448A1 (en) | 2003-10-02 | 2005-06-23 | Dakota Technologies, Inc. | Apparatus and methods for fluorescent detection of nucleic acids |
US20060134644A1 (en) | 2003-10-28 | 2006-06-22 | Dakota Technologies, Inc. | Apparatus and methods for detecting target analyte |
US7122799B2 (en) | 2003-12-18 | 2006-10-17 | Palo Alto Research Center Incorporated | LED or laser enabled real-time PCR system and spectrophotometer |
US7489401B2 (en) | 2004-03-01 | 2009-02-10 | National Institute Of Advanced Industrial Science And Technology | Device for detecting emission light of micro-object |
-
2007
- 2007-05-17 EP EP12178744.4A patent/EP2535427A3/fr not_active Withdrawn
- 2007-05-17 WO PCT/US2007/069197 patent/WO2008070198A2/fr active Application Filing
- 2007-05-17 JP JP2009511244A patent/JP2009537152A/ja active Pending
- 2007-05-17 EP EP07783905A patent/EP2027251A4/fr not_active Ceased
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0363143A2 (fr) * | 1988-10-06 | 1990-04-11 | Coy Corporation | Appareil de régulation de température |
JPH07185363A (ja) * | 1993-12-27 | 1995-07-25 | Shuji Ueda | 加熱冷却器 |
US20030157721A1 (en) * | 1998-08-13 | 2003-08-21 | Symyx Technologies, Inc. | Parallel reactor with internal sensing and method of using same |
US20020086417A1 (en) * | 2000-12-29 | 2002-07-04 | Shuqi Chen | Sample processing device and method |
US20040178357A1 (en) * | 2003-02-28 | 2004-09-16 | Applera Corporation | Excitation and emission filter |
WO2004105947A2 (fr) * | 2003-05-23 | 2004-12-09 | Bio-Rad Laboratories, Inc. | Controle de temperature localise pour ensemble spatial de milieux reactionnels |
Also Published As
Publication number | Publication date |
---|---|
EP2535427A2 (fr) | 2012-12-19 |
WO2008070198A2 (fr) | 2008-06-12 |
EP2535427A3 (fr) | 2013-04-24 |
WO2008070198A3 (fr) | 2009-04-16 |
JP2009537152A (ja) | 2009-10-29 |
WO2008070198A8 (fr) | 2008-12-24 |
EP2027251A2 (fr) | 2009-02-25 |
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Legal Events
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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Effective date: 20081212 |
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Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
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AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
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R17D | Deferred search report published (corrected) |
Effective date: 20090416 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/10 20060101ALI20090430BHEP Ipc: C12Q 1/68 20060101AFI20090430BHEP |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20100406 |
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17Q | First examination report despatched |
Effective date: 20100722 |
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RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: MALTEZOS, GEORGE Inventor name: JOHNSTON, MATTHEW Inventor name: WALKER, CHRISTOPHER I. Inventor name: GOODWIN, DAVID Inventor name: SCHERER, AXEL |
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