EP2024006B1 - Vorrichtung zur nervenstimulation bei einem patienten - Google Patents
Vorrichtung zur nervenstimulation bei einem patienten Download PDFInfo
- Publication number
- EP2024006B1 EP2024006B1 EP07794979.0A EP07794979A EP2024006B1 EP 2024006 B1 EP2024006 B1 EP 2024006B1 EP 07794979 A EP07794979 A EP 07794979A EP 2024006 B1 EP2024006 B1 EP 2024006B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- current
- therapy
- mode
- nerve
- test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/08—Accessories or related features not otherwise provided for
- A61B2090/0814—Preventing re-use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/3752—Details of casing-lead connections
Definitions
- the present invention is directed to nerve stimulators, and more particularly to electrical leads for nerve stimulators.
- US 2005/0171576 A1 discloses an electro-nerve stimulation apparatus including a pulse generator, a first electrically conductive, insulated lead wire, a second electrically conductive, insulated lead wire, an electrically conductive transcutaneous electrode and an electrically conductive percutaneous needle electrode.
- the lead wire set includes a single-use mechanism adapted to effectively discourage reuse of the electrodes.
- US 2002/0183804 A1 discloses an electro-nerve stimulator system including a pulse generator for generating current pulses with a transcutaneous patch and percutaneous needle for delivering current pulses to selected stimulation sites.
- EMS electronic muscle stimulation
- TENS transcutaneous electrical nerve stimulation
- Urologists and obstetrician/gynecologists have used a form of TENS for pelvic floor stimulation to treat incontinence and pelvic pain.
- medical providers have used a variety of implantable and percutaneous stimulators to manage pain, to create local nerve blocks, and to treat incontinence, Parkinson's disease, and multiple sclerosis.
- Transcutaneous stimulators i.e., stimulators which do not physically penetrate the skin surface
- transcutaneous stimulators often require higher current levels than percutaneous and implantable stimulators. Higher current levels can cause irritation and discomfort when used for extended periods.
- transcutaneous stimulators stimulate on the skin surface, their target site usually covers a large area. Thus, transcutaneous stimulators may not be highly effective for direct nerve stimulation.
- Implantable stimulators can free a patient from the need for constant and frequent manual treatment. However, implantable stimulators can cause mild discomfort, and often cause more severe implant-site pain.
- Percutaneous stimulators provide direct nerve stimulation without the invasiveness of an implant.
- a conducting needle is inserted to provide electrical stimulation to a target nerve.
- the needle is electrically connected to a controller by a series of leads, often bound together at one end as a cable that connects to the controller.
- Leads for percutaneous stimulators may be designated for single-use only, particularly if they have not been tested or validated for multiple uses. Since such leads should not be used multiple times, there exists a need for electrical leads that ensure against multiple uses.
- One aspect, not included in the invention, is a method for stimulating a posterior tibial nerve of a patient, comprising determining an initial therapy current level for the patient; delivering a therapy current to the nerve through a lead set expressing a "use" status, the therapy current being initially set to the initial therapy current level; and changing the lead set to express a "do not use” status within a predetermined time after start of the therapy current delivering step.
- Another aspect, not included in the invention, is a method for stimulating a posterior tibial nerve of a patient with therapy current, comprising activating a stimulator, the stimulator comprising a handheld controller coupled to a lead set having a fuse disposed therein; entering a test mode; adjusting a test current during test mode to set a final test current level; exiting the test mode; entering a therapy mode when the test mode is exited; forming an initial therapy current level from the final test current level; providing a therapy current through the lead set; blowing the fuse within a predetermined time after entering therapy mode; and exiting the therapy mode within a predetermined time after the fuse is blown.
- a posterior tibial nerve stimulator comprising a controller, the controller comprising a stored program of digital instructions for executing a test mode to determine an initial therapy current level for the patient; executing a therapy mode to deliver a therapy current to the nerve through a lead set expressing a "use" status, the current being initially set to the initial therapy current level; and causing the lead set to express a "do not use” status within a predetermined time after start of execution of the therapy mode.
- Another aspect of the present invention is an apparatus for stimulating a nerve of a patient, comprising means for determining an initial therapy current level for the patient; means for delivering a therapy current to the nerve through a lead set expressing a "use" status, the therapy current being initially set to the initial therapy current level; and means for changing the lead set to express a "do not use” status within a predetermined time after start of the therapy current delivering step.
- Nerve and muscle stimulation may be used by medical providers to treat a variety of ailments.
- urinary incontinence may be treated by stimulating the sacral nerves, which affect bladder control.
- One such treatment may be done in a percutaneous manner by inserting a fine gauge needle into the posterior tibial nerve just above the ankle and applying an electrical stimulation to the needle.
- the tibial nerve carries the electrical stimulation up the leg to the S3 region of the lower spinal cord. Electrical stimulation near the S3 region is effective in treating chronic pelvic pain, fecal incontinence, nocturnal urinary frequency, interstitial cystitis symptoms of urinary frequency, urinary urgency, and urinary urge incontinence, and overactive bladder symptoms of urinary frequency, urinary urgency and urinary urge incontinence.
- suitable single-use leads rely on the conductivity between two particular electrical connections to determine if the lead set have been used.
- the two particular connections have a fuse between them that conducts electricity prior to use. Once a particular set of criteria is met that determines that the lead set should not be reused, the fuse is deliberately blown, and the two particular connections no longer conduct electricity from one to the other.
- the two particular connections are coupled to a controller that can sense the conductivity between them and can also generate enough current to blow the fuse when required.
- the fuse and the electrical connections to the fuse are electrically isolated from the leads that deliver the stimulation current, although they may be combined with the stimulation current leads if desired.
- FIG. 1 shows exemplary nerve stimulator 11 that has a set of single-use electrical leads.
- the leads are shown in FIG. 1 as individual wires emerging from a controller 10, although it will be understood that any or all of the leads may be packaged in a connector to simplify connecting or removing the leads from the controller 10.
- the controller 10 may include circuitry for monitoring time and generating a prescribed amount of current.
- the current may be AC, DC, or may alternatively be pulsed.
- the controller 10 may also include a battery or may alternatively use an external source of power.
- the controller 10 has four electrical connections or leads, although it may alternatively have more or fewer electrical connections, such as 3, 5, 6 and so forth.
- two leads 16 and 18 provide a current through a portion of the patient's body, and the other two leads 17 and 19 are used for ensuring that the electrical leads are used for only a single therapy session.
- Lead 16 connects the controller 10 to a transcutaneous electrode 14 that is placed in a suitable location on the exterior of the patient's body.
- the electrode 14 may be conductive or one or both sides, and may optionally have an adhesive that sticks to the patient's body.
- Lead 18 connects the controller 10 to a percutaneous electrode needle 12 that is inserted into the patient's body at a stimulation site 15 and connects electrically near a nerve or bundle of nerves to be stimulated.
- the connector generates a voltage difference between leads 16 and 18, so that current flows between the electrode 14 and the needle 12. This current is denoted as arrow "i" in FIG. 1 .
- the remaining two leads 17 and 19 are connected to a fuse 13.
- the controller contains circuitry that can sense whether or not fuse 13 is blown, by generating a relatively small voltage between leads 17 and 19 and sensing whether or not any current is flowing through leads 17 and 19.
- the controller also contains circuitry that can deliberately blow the fuse 13, by generating a relatively large voltage between leads 17 and 19.
- the voltages used in leads 17 and 19 are determined in part by the fuse 13, and are typically low enough to not damage any tissue if it should come in contact with the leads 17 or 19.
- the fuse 13 and the electrical leads 16, 17, 18 and 19 are bundled together at the controller 10 and connect to the controller 10 through a connector.
- a simulator 20 having an exemplary connector 22 is shown in FIG. 2 , along with typical a controller unit 21, leads 25 and 26, an electrode 27, and a clip 28 that attaches to a needle 29.
- the controller unit 21 may be a portable unit, with a lightweight, ergonomic, handheld design.
- the controller unit 21 may have electronic touch pad controls or other suitable buttons or switches for entering data or changing the status of the controller unit 21.
- the controller unit 21 may have raised and embossed buttons, which provide tactile feedback to the user while protecting the controller unit 21 from moisture, contamination, and so forth. It will be readily understood by one of ordinary skill in the art that the controller may use any combination of buttons, switches, joysticks, levers, or any other suitable adjustment mechanism.
- the controller unit 21 may have a display such as an LCD screen for providing operational status and visual feedback information to the user.
- the controller unit 21 includes a connection site to mate with a connector 22.
- the connection site may be a one-way fit connection site to ensure that the connector 22 for the leads cannot be plugged in backwards.
- the connector 22 may be keyed to the connection site in any desired manner, such as extended ribs, chamfers, spacing of the pins or sockets, and so forth.
- the controller unit 21 contains the electronics suitable for providing a current for stimulating the desired nerve in the patient.
- any suitable current scheme may be used, such as direct current (“DC”), alternating current (“AC”) with a continuously varying current, AC with a pulsed current, or a combination of any of these.
- DC direct current
- AC alternating current
- the specific current settings in the following three paragraphs are merely exemplary.
- the controller unit 21 may have twenty current setting levels, ranging from level “0" to level “19", representing a current range of 0 mA to approximately 9 mA. At level “0”, the device produces 0 mA current. At level “1”, the current is 0.15 mA. At level “2”, the current level is 0.5 mA, and so forth. Each subsequent level represents a 0.5 mA increase. It will be understood that other increments and levels may be used as well.
- the controller unit 21 may provide a pulsed current.
- the frequency of the pulses may be fixed at 20 Hz.
- the pulse width may be 200 microseconds.
- the pulse waveform may be square. It will be understood that other suitable frequencies, pulse widths, and waveforms may be used as well, and may optionally be adjustable.
- the internal resistance of the controller unit 21 may be varied by the controller unit 21 from 500 to 4000 Ohms in order to provide the desired current. This range is merely exemplary, and other suitable ranges may be used as well.
- buttons on the controller unit 21 in greater detail. These descriptions are merely exemplary.
- the controller unit 21 may have a "power" button that turns the power on or off. To turn the power on or off, the user may be required to depress the power button for an extended period, such as approximately two seconds, to protect the controller unit 21 from inadvertent status changes.
- the controller may have a "test” button, which begins “test mode". "Test mode” is described in greater detail later in this document.
- the default current setting may be "0", or 0 mA.
- the final current setting may be the baseline setting in "therapy mode”, which is also described in greater detail later in this document.
- the user may be required to depress the test mode button for an extended period, such as approximately two seconds. This may protect the controller unit 21 from inadvertent status changes.
- the controller unit 21 may have a "therapy” button, which begins “therapy mode".
- the default current setting for therapy mode may be the final current setting in test mode.
- the current adjustment button (described below) may be used to increase or decrease the level at any time.
- the user may be required to depress the therapy mode button for an extended period, such as approximately two seconds. This may protect the controller unit 21 from inadvertent status changes.
- the controller unit 21 may have a "stop" button that stops the flow of current in test or therapy mode. If treatment is stopped or interrupted during therapy mode, the remaining therapy mode time may be displayed. Once stopped, the treatment session may need to be restarted, beginning with test mode.
- controller unit 21 may have a "current adjustment” button, which increases or decreases current.
- the current may be adjustable in both test and therapy modes.
- the controller unit 21 may have a "battery level" icon.
- the number of horizontal lines displayed in the battery level icon may represent the remaining battery life. Seven horizontal lines may indicate a fully charged battery whereas one horizontal line may indicate that the battery is nearly empty. A flashing battery level icon may signal that a replacement battery may be needed.
- the controller unit 21 may emit a periodic beep when the battery is nearly empty, such as when only one line is displayed in the battery level icon.
- the controller unit 21 may be designed to prohibit the start of test mode if there is insufficient battery life remaining to complete the treatment.
- the controller unit 21 may have a "lead wire status" icon, which may indicate the functional status of the lead wire.
- the icon may flash if a new lead wire is required.
- the controller unit 21 may have an "inactive current” icon, which may indicate that current is not flowing through the lead set. This icon may signal that the user should check the security of the lead connector, the adherence of the surface electrode, and the placement of the needle electrode clip.
- the controller unit 21 may have an "active current” icon, which may indicate that current is actively flowing through the lead set.
- the controller unit 21 may have a "service required" icon. If a fault is detected, therapy mode may end and the service required icon may appear on the screen.
- the controller unit 21 may have a "treatment status" portion of the screen.
- the word “TEST” may appear on the screen.
- a countdown timer may appear in a portion of the display. This timer may indicate how much time is left in the therapy session.
- the word “END” may flash on the screen until shutdown.
- controller unit 21 may have a "current setting" portion of the screen, which may display the selected current setting.
- the current may be adjustable in both test and therapy modes.
- the leads transfers the electrical current from the controller unit 21 to the tibial nerve and may include one or more lead sets such as lead set 23, one or more percutaneous electrodes such as needle electrode 29, one or more surface electrodes such as electrode 27, and an optional alcohol pad (not shown).
- lead sets such as lead set 23, one or more percutaneous electrodes such as needle electrode 29, one or more surface electrodes such as electrode 27, and an optional alcohol pad (not shown).
- percutaneous electrodes such as needle electrode 29, one or more surface electrodes such as electrode 27, and an optional alcohol pad (not shown).
- the components of the lead set 23 create the non-sterile circuit interface between the controller unit 21 and the patient.
- a one-way fit connector 22 is attached to the proximal end of the lead wire 23.
- the distal end of the lead wire may be split into individual wires 25 and 26, with the split occurring at a fork 24.
- One wire 25 may be attached to an adhesive-backed surface electrode 27; the other wire 26 may be attached to a needle electrode clip 28.
- the needle electrode clip 28 clips to the needle electrode 29.
- the needle electrode 29 illustratively is a 34 gauge solid stainless steel needle, which may be packaged within a plastic guide tube with stop plug. Each needle electrode 29 may be supplied sterile (ethylene oxide) in an individual peel-open package.
- the alcohol pad may be prepackaged to clean the needle electrode insertion site.
- Percutaneous tibial nerve stimulation (PTNS) therapy involves placing the needle electrode 29 into the lower, inner aspect of either leg slightly cephalad to the medial malleolus.
- the surface electrode 27 is placed over the medial aspect of the calcaneous on the same leg.
- the lead set 23 first is plugged into the stimulator 21, and then the needle electrode clip 28 is clipped to the needle electrode 29.
- the stimulator 21 produces an adjustable electrical pulse that travels to the sacral nerve plexus via the tibial nerve. Among other functions, the sacral nerve plexus regulates bladder and pelvic floor function.
- the patient is typically treated once per week for 30 minutes for a period of 12 weeks. No decision to discontinue treatment should be made until the patient completes the 12 treatments.
- the time between treatment sessions may be slowly increased after the initial 12 treatments, with the patient closely monitored for the return of symptoms. If symptoms reappear or increase in severity, the patient's treatment schedule should revert to the last previously effective treatment schedule.
- the treatment length of 30 minutes and period of 12 weeks are merely exemplary, and any suitable length and period may be used.
- the following section describes a preferred treatment protocol 30 for each treatment session, shown as flow charts in FIGs. 3-5 . Because the protocol is lengthy, it is divided into sections numbered 1-8, with appropriately lettered subsections. The described protocol is merely exemplary. Alternatively, any suitable protocol may be used.
- the stimulator Before beginning any treatment session, it is advisable to check the battery level. To check the battery level, turn on the stimulator by pressing and holding the power button for approximately 2 seconds. An audible tone will sound and icons will appear on the screen. Battery replacement is recommended when there is only one line remaining in the battery level icon. To conserve battery power, the stimulator may be turned off during patient preparation. Note that the system is designed to prohibit the start of Test mode if there is insufficient battery life remaining to complete the treatment.
- Locate the insertion site for the needle electrode by identifying the location on the lower inner aspect of either leg that is approximately three fingerbreadths (5 cm or 2 inches) cephalad to the medial malleolus and approximately one fingerbreadth (2 cm or 3/4 inch) posterior to the tibia.
- the patient Place the patient in a comfortable position, supine or sitting, for easy access to the insertion site; for example, the patient may sit with the soles of the feet together and knees abducted and flexed. Open the sterile needle electrode package and remove the needle electrode/guide tube assembly.
- test mode by pressing and holding the test button for approximately 2 seconds (block 42).
- the default setting for test mode is level 0 (0 mA current). Note that if the inactive current icon appears, current is not flowing through the lead set. Check the security of the lead wire connector, the adherence of the surface electrode, and the placement of the needle electrode clip.
- Patient response is generally a toe flex or fan, or an extension of the entire foot.
- therapy mode can be entered by either (i) pressing the stop button to end test mode and then pressing the therapy button to start therapy mode; or (ii) pressing the therapy button while the test mode is still active. Note that the test mode is a prerequisite to therapy mode.
- the default current setting for therapy mode should be the final current setting in test mode.
- the current adjustment button can be used to increase or decrease the current level at any time during Therapy mode.
- Therapy mode time is automatically set for 30 minutes.
- therapy mode automatically ends the current becomes inactive (block 57) and the stimulator emits a series of three beeps.
- Treatments as described above are preferably administered periodically over a prescribed length of time.
- the treatments may include 12 sessions, typically once per week. After the initial 12 treatments, the time between treatments may slowly increase, with the patient closely monitored for the return of symptoms. If symptoms reappear or increase in severity, the patient's treatment schedule may revert to the last previously effective treatment schedule.
- test mode is used to determine a current value for treatment
- therapy mode administers treatment with the chosen current value. More specific aspects of these two modes are presented in the following paragraphs.
- the controller assumes that the leads have already been used (block 58).
- the controller produces a suitable signal, such as an audible beep or a visual cue on its display indicating that the leads need to be replaced.
- the controller does not enter test mode or therapy mode at this point. Alternatively, the controller may enter test mode but not therapy mode.
- the controller assumes that the leads are as yet unused, and allows the user to enter either test mode or therapy mode.
- test mode the user may manually step up the current (blocks 43, 44 and 45) until the patient's foot shows a response, such as a movement. Once a response is seen, the user may manually decrease the current by one increment (block 46) to a value that is to be used as a default in therapy mode. Test mode lasts for a particular amount of time, such as five minutes, then shuts off. The user can also manually exit test mode before the particular time expires. The user can exit and enter test mode an unlimited number of times, as long as the fuse in the leads is conducting. Entering or exiting test mode does not cause the controller to deliberately blow the fuse. Alternatively, the fuse may be blown after a predetermined number of test mode reentries.
- a default current value is determined from test mode (block 53; see also block 48 in FIG. 4 ) the user then begins therapy mode.
- the current may be increased or decreased at any time in therapy mode, although preferably the current remains fairly close to the default value for the full extent of therapy mode.
- Therapy mode may last for a fixed amount of time, although the user can exit at any time.
- therapy mode triggers the deliberate blowing of the fuse in the leads (block 55) thereby ensuring that the leads are not reused after the therapy mode ends.
- the fuse may be blown after a particular amount of time spent in therapy mode (block 54) such as one minute, two minutes, five minutes or any other suitable time interval.
- the user may still complete the therapy mode (block 56) even though the fuse is non-conducting, although the user may not initiate another test mode or therapy mode using the blown leads. Alternatively, the user may initiate a test mode but not a therapy mode using the blown leads. Once therapy mode ends, the current is set to zero (block 57).
- the nerve stimulation system is effective not only for the treatment of chronic pelvic pain, fecal incontinence, nocturnal urinary frequency, interstitial cystitis symptoms of urinary frequency, urinary urgency, and urinary urge incontinence, and overactive bladder symptoms of urinary frequency, urinary urgency and urinary urge incontinence, but may also be effective for both nerve and muscle stimulation to treat other numerous conditions, including, for example, muscle and joint rehabilitation, chronic pain, Parkinson's disease, obesity, and multiple sclerosis. While many of these other conditions may use different nerve pathways than the one described herein, the nerve stimulator may be used in a similar manner for any suitable nerve pathway in the body. In addition, the system may be.used to manage pain and create local nerve blocks, as well as in any other application in which it is desirable to provide electrical nerve and/or muscle stimulation.
- the lead set may contain a "status flag” element to indicate whether the lead set has been used.
- the status flag element is reset by default at “use,” and once a particular set of criteria is met that determines that the leads should not be reused, the status flag element is set at "do not use.”
- the controller senses the lead set status as indicated by the status flag element, and is also capable of setting the status flag element at "do not use” when required.
- FIGS. 6-11 illustrate a variety of possible techniques which may be implemented in a connector for ensuring single use.
- a connector 100 includes two ports A and B corresponding to stimulation current lead wires 102 and 104 (also designated by corresponding reference letters A and B).
- FIG. 7 shows one type of status flag, illustratively a fuse 120, which may be blown and subsequently sensed by a controller (not shown) through a third port C to indicate that the lead set has been used.
- a controller not shown
- the connector 100 may include another type of status flag, illustratively a single wire serial read/write non-volatile erasable, programmable read only memory (EPROM) 122, which may be programmed and subsequently read by a controller through port C to indicate that the lead set has been used.
- EPROM programmable read only memory
- Other types of memory may be used as well, including single and multiple bit memory and Flash memory.
- Other types of devices may be used as well, including digital potentiometers.
- FIGS. 9 and 10 show a connector 106 that incorporates both a serial read/write non-volatile EPROM 123 and a fuse 120.
- the EPROM 123 may be programmed with information to instruct a controller to burn out the fuse 120 after a preselected time period, or to generate a current spike to burn out the fuse 120 after expiration of a preselected time period.
- Other components shown in FIG. 10 include a resister 124 and a Zener diode 126.
- FIG. 11 shows an illustrative mechanical mechanism that may be employed, in which a pin 128 is biased within port C.
- the mechanism is actuated to release the biased pin 128.
- the released pin 128 prevents the connector from being reinserted into the female receptacle to prevent reuse.
- the transcutaneous electrode and the percutaneous electrode may be implemented in any desired manner. While FIG. 2 shows a needle clip 28, for example, the lead may terminate in a needle without the intervening clip, or equivalents such as conductive tape may be used.
- a suitable conductive tape is described in US Patent US 7 536 226 B2, issued May 19, 2009 to Williams et al .
- a suitable tape member may have various layers sandwiched together, including a non-electrically conductive top layer, an intermediate electrically conductive foil layer, and a bottom electrically conductive adhesive layer. The opposing ends of the tape member are folded over onto each other and over the terminal end of the percutaneous needle electrode.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Electrotherapy Devices (AREA)
Claims (4)
- Vorrichtung zur Stimulation eines Nervs, umfassend:ein Mittel zum Bestimmen eines anfänglichen Therapiestrompegels für einen Patienten, wobei das Bestimmungsmittel einen Prüfmodussteuermechanismus aufweist, der an einer Handsteuereinheit (21) bereitgestellt ist, wobei die Steuereinheit (21) einen darin montierten Anschlusspunkt zum Aufnehmen einer Kabelgarnitur (23) hat, wobei die Kabelgarnitur mehrere Kabel (16, 18, 25, 26, 102, 104, 108, 110, 114, 116, A, B), die darin angeordnet und mit an den Patienten angelegten Elektroden (27, 28) gekoppelt sind, und mehrere Kabel (17, 19, A, B, C, D), die mit einem darin angeordneten Statusmarkierungselement (13, 120, 122, 123, 124, 126, 128) gekoppelt sind, hat, wobei der Anschlusspunkt elektrische Verbindungen zu den Kabeln, die mit den Elektroden gekoppelt sind, und zu den Kabeln, die mit dem Statusmarkierungselement gekoppelt sind, bereitstellt, die Steuereinheit (21) zum Einleiten eines Prüfmodus (42), in dem Elektronik in der Steuereinheit einen Prüfstrom (43) zu den elektrischen Verbindungen zu den Kabeln, die mit den Elektroden gekoppelt sind, zum Einstellen des Prüfstroms auf einen endgültigen Prüfstrompegel (43, 46) auf Basis einer Reaktion des Patienten auf die Stimulation des Nervs durch den Prüfstrom (45) bereitstellt, wobei der anfängliche Therapiestrompegel für den Patienten gleich dem endgültigen Therapiestrompegel (48) ist;ein Mittel zum Abgeben eines Therapiestroms durch die Kabelgarnitur an den Nerv, das einen "Benutzen"-Status ausdrückt, wobei der Therapiestrom zu Beginn der Abgabe des Therapiestroms auf den anfänglichen Therapiestrompegel eingestellt wird, wobei das Abgabemittel einen an der Steuereinheit (21) bereitgestellten Therapiemodussteuermechanismus zum Einleiten eines Therapiemodus (52) aufweist, bei dem Elektronik in der Steuereinheit den Therapiestrom (53) zu den elektrischen Verbindungen zu den Kabeln, die mit den Elektroden gekoppelt sind, bereitstellt, wobei der Therapiestrom anfänglich auf den anfänglichen Therapiestrompegel (53) eingestellt wird; undein Mittel zum Ändern der Kabelgarnitur, so dass sie einen "nicht benutzen"-Status ausdrückt, innerhalb einer vorbestimmten Zeit nach Beginn der Abgabe des Therapiestroms, wobei das Änderungsmittel Elektronik in der Steuereinheit aufweist zum Einstellen des Statusmarkierungselements auf "nicht benutzen" (54, 55) durch die elektrischen Verbindungen zu den Kabeln, die mit dem Statusmarkierungselement gekoppelt sind, während der Therapiestrom bereitgestellt wird;wobei die Steuereinheit ferner eine Schaltungsanordnung zum Erkennen des Kabelgarniturstatus, wie er vom Statusmarkierungselement angezeigt wird (51, 58), durch die elektrischen Verbindungen zu den Kabeln, die mit dem Statusmarkierungselement gekoppelt sind, und zum Deaktivieren des Einleitens des Therapiemodus (59), wenn das Statusmarkierungselement auf "nicht benutzen" eingestellt ist,wobei das Statusmarkierungselement eine Sicherung (13, 120) ist und Elektronik in der Steuereinheit eine erste Spannung an die elektrischen Verbindungen zu den Kabeln anlegt, die mit der Sicherung gekoppelt sind, während der Therapiestrom bereitgestellt wird, zum Auslösen der Sicherung (55) undwobei die Schaltungsanordnung in der Steuereinheit eine zweite Spannung an die elektrischen Verbindungen zu den Kabeln anlegt, die mit der Sicherung gekoppelt sind, zum Erkennen, wenn die Sicherung ausgelöst (51) wurde, und zum Deaktivieren des Einleitens des Therapiemodus, wenn die Sicherung ausgelöst wurde (59) .
- Vorrichtung zur Stimulation eines Nervs nach Anspruch 1, die ferner einen Stromanpassungssteuermechnismus aufweist, der an der Steuereinheit (21) bereitgestellt ist, wobei:der Stromanpassungssteuermechanismus während des Prüfmodus zum Variieren des Prüfstroms (43, 46) wirksam ist undder Stromanpassungssteuermechanismus während des Therapiemodus zum Variieren des Prüfstroms (37) wirksam ist.
- Vorrichtung zur Stimulation eines Nervs nach Anspruch 1, wobei der Prüfmodussteuermechanismus Folgendes aufweist:einen Prüfmodusknopf zum Einleiten des Prüfmodus undeinen Stromanpassungsknopf zum Einstellen des Prüfstroms auf den endgültigen Prüfstrompegel auf Basis der Reaktion des Patienten auf die Stimulation des Nervs durch den Prüfstrom.
- Vorrichtung zur Stimulation eines Nervs nach Anspruch 1, wobei der Therapiemodussteuermechanismus Folgendes aufweist:einen Therapiemodusknopf zum Einleiten des Therapiemodus undeinen Stromanpassungsknopf zum Variieren des Pegels des Therapiestroms während des Therapiemodus.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80129606P | 2006-05-18 | 2006-05-18 | |
PCT/US2007/011820 WO2007136694A2 (en) | 2006-05-18 | 2007-05-17 | Method and apparatus for stimulating a nerve of a patient |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2024006A2 EP2024006A2 (de) | 2009-02-18 |
EP2024006A4 EP2024006A4 (de) | 2009-05-27 |
EP2024006B1 true EP2024006B1 (de) | 2018-10-10 |
Family
ID=38723829
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07794979.0A Active EP2024006B1 (de) | 2006-05-18 | 2007-05-17 | Vorrichtung zur nervenstimulation bei einem patienten |
Country Status (4)
Country | Link |
---|---|
US (2) | US7668598B2 (de) |
EP (1) | EP2024006B1 (de) |
DK (1) | DK2024006T3 (de) |
WO (1) | WO2007136694A2 (de) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8812114B2 (en) | 2001-10-18 | 2014-08-19 | Uroplasty, Inc. | Lead set for nerve stimulator and method of operation thereof |
CA2553901C (en) | 2004-01-22 | 2015-01-20 | Rehabtronics Inc. | Method of routing electrical current to bodily tissues via implanted passive conductors |
US9610459B2 (en) | 2009-07-24 | 2017-04-04 | Emkinetics, Inc. | Cooling systems and methods for conductive coils |
US9339641B2 (en) | 2006-01-17 | 2016-05-17 | Emkinetics, Inc. | Method and apparatus for transdermal stimulation over the palmar and plantar surfaces |
US20100168501A1 (en) * | 2006-10-02 | 2010-07-01 | Daniel Rogers Burnett | Method and apparatus for magnetic induction therapy |
DK2024006T3 (en) * | 2006-05-18 | 2019-02-04 | Uroplasty Inc | Apparatus for stimulation of a patient's nerve |
US11224742B2 (en) | 2006-10-02 | 2022-01-18 | Emkinetics, Inc. | Methods and devices for performing electrical stimulation to treat various conditions |
US10786669B2 (en) | 2006-10-02 | 2020-09-29 | Emkinetics, Inc. | Method and apparatus for transdermal stimulation over the palmar and plantar surfaces |
WO2008042902A2 (en) * | 2006-10-02 | 2008-04-10 | Emkinetics, Inc. | Method and apparatus for magnetic induction therapy |
US11679262B2 (en) | 2007-03-09 | 2023-06-20 | Mainstay Medical Limited | Systems and methods for restoring muscle function to the lumbar spine |
EP2125100B1 (de) | 2007-03-09 | 2021-08-25 | Mainstay Medical Limited | Muskelstimulator |
US10925637B2 (en) * | 2010-03-11 | 2021-02-23 | Mainstay Medical Limited | Methods of implanting electrode leads for use with implantable neuromuscular electrical stimulator |
US9072897B2 (en) | 2007-03-09 | 2015-07-07 | Mainstay Medical Limited | Systems and methods for restoring muscle function to the lumbar spine |
US11679261B2 (en) | 2007-03-09 | 2023-06-20 | Mainstay Medical Limited | Systems and methods for enhancing function of spine stabilization muscles associated with a spine surgery intervention |
US11331488B2 (en) | 2007-03-09 | 2022-05-17 | Mainstay Medical Limited | Systems and methods for enhancing function of spine stabilization muscles associated with a spine surgery intervention |
US8738137B2 (en) | 2007-08-23 | 2014-05-27 | Bioness Inc. | System for transmitting electrical current to a bodily tissue |
US9757554B2 (en) | 2007-08-23 | 2017-09-12 | Bioness Inc. | System for transmitting electrical current to a bodily tissue |
US20090326602A1 (en) * | 2008-06-27 | 2009-12-31 | Arkady Glukhovsky | Treatment of indications using electrical stimulation |
US9724508B2 (en) * | 2009-03-09 | 2017-08-08 | Boston Scientific Neuromodulation Corporation | Electronic identification of external cables for external medical devices |
US9878154B2 (en) * | 2009-10-01 | 2018-01-30 | University of Pittsburgh—of the Commonwealth System of Higher Education | Non-invasive method to treat urological and gastrointestinal disorders |
CA2778963A1 (en) * | 2009-10-26 | 2011-05-05 | Emkinetics, Inc. | Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues |
AU2011224323B2 (en) | 2010-03-11 | 2016-06-23 | Mainstay Medical Limited | Modular stimulator for treatment of back pain, implantable RF ablation system and methods of use |
US9999763B2 (en) | 2012-06-13 | 2018-06-19 | Mainstay Medical Limited | Apparatus and methods for anchoring electrode leads adjacent to nervous tissue |
US11684774B2 (en) | 2010-03-11 | 2023-06-27 | Mainstay Medical Limited | Electrical stimulator for treatment of back pain and methods of use |
US11786725B2 (en) | 2012-06-13 | 2023-10-17 | Mainstay Medical Limited | Systems and methods for restoring muscle function to the lumbar spine and kits for implanting the same |
US9950159B2 (en) | 2013-10-23 | 2018-04-24 | Mainstay Medical Limited | Systems and methods for restoring muscle function to the lumbar spine and kits for implanting the same |
US20120105136A1 (en) * | 2010-10-27 | 2012-05-03 | Thermaltherapeutic Systems, Inc. | Fuse link system for disposable component |
WO2012174330A1 (en) * | 2011-06-16 | 2012-12-20 | Advanced Uro-Solutions, Llc | Percutaneous tibial nerve stimulator |
US9076187B1 (en) | 2011-06-16 | 2015-07-07 | Advanced Uro-Solutions, Llc | Medical device payment system |
CA2843767C (en) | 2011-08-02 | 2019-07-09 | Mainstay Medical Limited | Apparatus for anchoring electrode leads for use with implantable neuromuscular electrical stimulator |
US9731126B2 (en) | 2011-11-15 | 2017-08-15 | Neurometrix, Inc. | Transcutaneous electrical nerve stimulator with automatic detection of leg orientation and leg motion for enhanced sleep analysis, including enhanced transcutaneous electrical nerve stimulation (TENS) using the same |
US11247040B2 (en) | 2011-11-15 | 2022-02-15 | Neurometrix, Inc. | Dynamic control of transcutaneous electrical nerve stimulation therapy using continuous sleep detection |
WO2013074809A1 (en) | 2011-11-15 | 2013-05-23 | Neurometrix, Inc. | Apparatus and method for relieving pain using transcutaneous electrical nerve stimulation |
US10112040B2 (en) | 2011-11-15 | 2018-10-30 | Neurometrix, Inc. | Transcutaneous electrical nerve stimulation using novel unbalanced biphasic waveform and novel electrode arrangement |
US9827420B2 (en) | 2013-03-29 | 2017-11-28 | Neurometrix, Inc. | Transcutaneous electrical nerve stimulator with user gesture detector and electrode-skin contact detector, with transient motion detector for increasing the accuracy of the same |
US11259744B2 (en) | 2011-11-15 | 2022-03-01 | Neurometrix, Inc. | Transcutaneous electrical nerve stimulator with automatic detection of leg orientation and leg motion for enhanced sleep analysis, including enhanced transcutaneous electrical nerve stimulation (TENS) using the same |
US10279179B2 (en) | 2013-04-15 | 2019-05-07 | Neurometrix, Inc. | Transcutaneous electrical nerve stimulator with automatic detection of user sleep-wake state |
US10335595B2 (en) | 2011-11-15 | 2019-07-02 | Neurometrix, Inc. | Dynamic control of transcutaneous electrical nerve stimulation therapy using continuous sleep detection |
US9675801B2 (en) | 2011-11-15 | 2017-06-13 | Neurometrix, Inc. | Measuring the “on-skin” time of a transcutaneous electrical nerve stimulator (TENS) device in order to minimize skin irritation due to excessive uninterrupted wearing of the same |
EP2794000B1 (de) | 2011-12-19 | 2016-03-30 | Mainstay Medical Limited | Vorrichtung zur rehabilitation eines muskels und zur überprüfung des rehabilitationsfortschritts |
US8968294B2 (en) | 2012-04-17 | 2015-03-03 | Covidien Lp | Single or limited use device designs |
GB201207490D0 (en) * | 2012-04-30 | 2012-06-13 | Emblation Ltd | Apparatus and method for determining a status of a medical device component |
US9186501B2 (en) | 2012-06-13 | 2015-11-17 | Mainstay Medical Limited | Systems and methods for implanting electrode leads for use with implantable neuromuscular electrical stimulator |
US10195419B2 (en) | 2012-06-13 | 2019-02-05 | Mainstay Medical Limited | Electrode leads for use with implantable neuromuscular electrical stimulator |
JP2016515428A (ja) | 2013-03-29 | 2016-05-30 | ニューロメトリックス・インコーポレーテッド | 電極−皮膚インピーダンスを使用する皮膚電極剥離の検出 |
US10940311B2 (en) | 2013-03-29 | 2021-03-09 | Neurometrix, Inc. | Apparatus and method for button-free control of a wearable transcutaneous electrical nerve stimulator using interactive gestures and other means |
CN105431196B (zh) | 2013-04-15 | 2019-02-01 | Gsk消费者健康有限公司 | 具有用户睡眠—觉醒状态的自动检测的经皮电神经刺激器 |
US9566109B2 (en) | 2013-07-18 | 2017-02-14 | Covidien Lp | Limited-use surgical devices |
US9610442B2 (en) | 2015-05-21 | 2017-04-04 | The Governing Council Of The University Of Toronto | Systems and methods for treatment of urinary dysfunction |
US10556107B2 (en) | 2013-11-27 | 2020-02-11 | Ebt Medical, Inc. | Systems, methods and kits for peripheral nerve stimulation |
US20160263376A1 (en) | 2013-11-27 | 2016-09-15 | The Governing Council Of The University Of Toronto | Systems and methods for improved treatment of overactive bladder |
US11633593B2 (en) | 2013-11-27 | 2023-04-25 | Ebt Medical, Inc. | Treatment of pelvic floor disorders using targeted lower limb nerve stimulation |
CA3190484A1 (en) | 2013-11-27 | 2015-06-04 | Ebt Medical, Inc. | Systems and methods of enhancing electrical activation of nervous tissue |
US9606605B2 (en) | 2014-03-07 | 2017-03-28 | Apple Inc. | Dynamic voltage margin recovery |
EP3797729A1 (de) | 2014-04-09 | 2021-03-31 | Gyrus ACMI, Inc. d/b/a Olympus Surgical Technologies America | Durchsetzungsvorrichtung für produkt mit begrenzter nutzung |
EP3180071B1 (de) * | 2014-08-15 | 2021-09-22 | Axonics, Inc. | Externe impulsgeneratorvorrichtung und zugehörige system zur versuchsnervenstimulation |
EP3180069B1 (de) | 2014-08-17 | 2020-05-13 | Nine Continents Medical, Inc. | Implantierbares miniaturneurostimulatorsystem für ischiasnerven und deren verzweigungen |
US10471268B2 (en) | 2014-10-16 | 2019-11-12 | Mainstay Medical Limited | Systems and methods for monitoring muscle rehabilitation |
WO2016106182A1 (en) | 2014-12-23 | 2016-06-30 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Devices, systems and methods for treating urological and gastrointestinal disorders by electrical stimulation of the foot |
ES2725489T3 (es) | 2015-01-09 | 2019-09-24 | Axonics Modulation Tech Inc | Control remoto del paciente y procedimientos de uso asociados con un sistema de estimulación nerviosa |
JP1543097S (de) * | 2015-03-27 | 2016-02-08 | ||
USD778453S1 (en) * | 2015-04-07 | 2017-02-07 | Meditech International Inc. | Controller |
DE102015217466A1 (de) * | 2015-09-11 | 2017-03-16 | Birgitt Lantzberg | Gerät zur transkutanen elektrischen Stimulation von Muskeln und/oder Nerven am menschlichen Körper |
US10327810B2 (en) | 2016-07-05 | 2019-06-25 | Mainstay Medical Limited | Systems and methods for enhanced implantation of electrode leads between tissue layers |
AU2017297399B2 (en) * | 2016-07-13 | 2020-04-09 | GSK Consumer Healthcare S.A. | Apparatus and method for automated compensation of transcutaneous electrical nerve stimulation for temporal fluctuations such as circadian rhythms |
US10555725B2 (en) | 2016-09-29 | 2020-02-11 | Gyrus Acmi, Inc. | Thermal mechanism to prevent reprocessing or reuse of mechanical surgical devices |
US10792495B2 (en) | 2016-12-01 | 2020-10-06 | Thimble Bioelectronics, Inc. | Neuromodulation device and method for use |
US11235142B2 (en) | 2016-12-23 | 2022-02-01 | Neurometrix, Inc. | “Smart” electrode assembly for transcutaneous electrical nerve stimulation (TENS) |
US11058877B2 (en) | 2017-05-30 | 2021-07-13 | Neurometrix, Inc. | Apparatus and method for the automated control of transcutaneous electrical nerve stimulation based on current and forecasted weather conditions |
USD837394S1 (en) | 2017-07-11 | 2019-01-01 | Neurometrix, Inc. | Transcutaneous electrical nerve stimulation (TENS) device |
USD857910S1 (en) | 2017-09-21 | 2019-08-27 | Neurometrix, Inc. | Transcutaneous electrical nerve stimulation device |
USD865986S1 (en) | 2017-09-21 | 2019-11-05 | Neurometrix, Inc. | Transcutaneous electrical nerve stimulation device strap |
USD836789S1 (en) * | 2017-10-30 | 2018-12-25 | JKH Health Co., Ltd. | Handheld stimulator |
USD861903S1 (en) | 2018-05-15 | 2019-10-01 | Neurometrix, Inc. | Apparatus for transcutaneous electrical nerve stimulation |
US11883661B2 (en) | 2018-12-07 | 2024-01-30 | Neurometrix, Inc. | Intelligent determination of therapeutic stimulation intensity for transcutaneous electrical nerve stimulation |
WO2020163046A1 (en) * | 2019-02-08 | 2020-08-13 | Boston Scientific Neuromodulation Corporation | System for delivering prescribed neuromodulation dose |
US11848090B2 (en) | 2019-05-24 | 2023-12-19 | Axonics, Inc. | Trainer for a neurostimulator programmer and associated methods of use with a neurostimulation system |
US11452559B2 (en) | 2019-06-25 | 2022-09-27 | Covidien Lp | Electrosurgical plug for energy activation of surgical instruments |
US11504179B2 (en) | 2019-06-25 | 2022-11-22 | Covidien Lp | Electrosurgical plug for energy activation of surgical instruments |
MX2023002140A (es) * | 2020-10-12 | 2023-07-04 | Neuvana Llc | Metodo para la calibracion de un estimulador nervioso transcutaneo. |
WO2023220382A1 (en) * | 2022-05-12 | 2023-11-16 | President And Fellows Of Harvard College | Wearable system for therapeutic afferent nerve electrical stimulation |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004034885A2 (en) * | 2002-10-15 | 2004-04-29 | Medtronic Inc. | Signal quality monitoring and control for a medical device system |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3893462A (en) | 1972-01-28 | 1975-07-08 | Esb Inc | Bioelectrochemical regenerator and stimulator devices and methods for applying electrical energy to cells and/or tissue in a living body |
US3995644A (en) | 1975-09-16 | 1976-12-07 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Percutaneous connector device |
US4408609A (en) | 1980-04-01 | 1983-10-11 | Professional Staff Association Of The Rancho Los Amigos Hospital, Inc. | Electrical muscle stimulation for treatment of scoliosis and other spinal deformities |
US4406288A (en) | 1981-04-06 | 1983-09-27 | Hugh P. Cash | Bladder control device and method |
US4535785A (en) | 1982-09-23 | 1985-08-20 | Minnesota Mining And Manufacturing Co. | Method and apparatus for determining the viability and survival of sensori-neutral elements within the inner ear |
US4519394A (en) | 1983-03-07 | 1985-05-28 | Trustees Of The University Of Pennsylvania | Method and apparatus for cathodic potential control in electrically induced osteogenesis |
EP0327304A1 (de) | 1988-02-01 | 1989-08-09 | Physio-Control Corporation | Wegwerf-Stimulationselektrode mit grosser Lagerbeständigkeit und verbessertem Stromdichteprofil |
US5094242A (en) | 1988-11-07 | 1992-03-10 | Regents Of The University Of California | Implantable nerve stimulation device |
US5056518A (en) | 1990-07-02 | 1991-10-15 | Electro-Biology, Inc. | Optimization of bone formation at cathodes |
US5573533A (en) * | 1992-04-10 | 1996-11-12 | Medtronic Cardiorhythm | Method and system for radiofrequency ablation of cardiac tissue |
US5557210A (en) | 1992-11-20 | 1996-09-17 | Pacesetter, Inc. | Universal cable connector for temporarily connecting implantable stimulation leads and implantable stimulation devices with a non-implantable system analyzer |
US5441520A (en) | 1993-04-06 | 1995-08-15 | Hewlett-Packard Corporation | Defibrillator patient connection system with automatic identification |
US5776171A (en) | 1994-09-06 | 1998-07-07 | Case Western Reserve University | Functional neuromuscular stimulation system |
US5645571B1 (en) * | 1995-08-01 | 1999-08-24 | Surviva Link Corp | Automated external defibrillator with lid activated self-test system |
US5695495A (en) | 1995-11-20 | 1997-12-09 | Ellman; Alan G. | Electrosurgical electrode for sclerotherapy |
US5983141A (en) | 1996-06-27 | 1999-11-09 | Radionics, Inc. | Method and apparatus for altering neural tissue function |
US5782892A (en) | 1997-04-25 | 1998-07-21 | Medtronic, Inc. | Medical lead adaptor for external medical device |
EP1003416A4 (de) | 1997-08-01 | 2006-08-23 | Harbinger Medical Inc | Anordnung und verfahren zur nicht-invasiven bestimmung der empfindlichkeit einer person bezüglich arrythmien |
US6055453A (en) | 1997-08-01 | 2000-04-25 | Genetronics, Inc. | Apparatus for addressing needle array electrodes for electroporation therapy |
US5906634A (en) | 1997-08-08 | 1999-05-25 | Cardiac Pacemakers, Inc. | Implantable device having a quick connect mechanism for leads |
US5857968A (en) | 1997-11-24 | 1999-01-12 | Benja-Athon; Anuthep | Coupling device in electroacupuncture |
GB2336214A (en) | 1998-01-16 | 1999-10-13 | David William Taylor | Preventionof multiple use of limited use devices |
US6493588B1 (en) | 1998-03-18 | 2002-12-10 | Mmc/Gatx Partnership No. 1 | Electro-nerve stimulator systems and methods |
US6141585A (en) | 1998-05-08 | 2000-10-31 | Intermedics Inc. | Implantable cardiac stimulator with electrode-tissue interface characterization |
US6735474B1 (en) * | 1998-07-06 | 2004-05-11 | Advanced Bionics Corporation | Implantable stimulator system and method for treatment of incontinence and pain |
US6516227B1 (en) | 1999-07-27 | 2003-02-04 | Advanced Bionics Corporation | Rechargeable spinal cord stimulator system |
US6904324B2 (en) * | 1999-12-01 | 2005-06-07 | Meagan Medical, Inc. | Method and apparatus for deploying a percutaneous probe |
US6701190B2 (en) * | 2000-10-10 | 2004-03-02 | Meagan Medical, Inc. | System and method for varying characteristics of electrical therapy |
DE10136642A1 (de) * | 2001-07-20 | 2003-02-06 | Biotronik Mess & Therapieg | Medizinisches Einweggerät |
US8812114B2 (en) | 2001-10-18 | 2014-08-19 | Uroplasty, Inc. | Lead set for nerve stimulator and method of operation thereof |
ES2377946T3 (es) | 2001-10-18 | 2012-04-03 | Uroplasty, Inc. | Sistema y procedimientos de neuroestimulación eléctrica |
US7139615B2 (en) * | 2001-10-31 | 2006-11-21 | Koninklijke Philips Electronics, N.V. | Single separable electrode and self-contained pad viability tester |
DK2024006T3 (en) * | 2006-05-18 | 2019-02-04 | Uroplasty Inc | Apparatus for stimulation of a patient's nerve |
US7921106B2 (en) * | 2006-08-03 | 2011-04-05 | Microsoft Corporation | Group-by attribute value in search results |
-
2007
- 2007-05-17 DK DK07794979.0T patent/DK2024006T3/en active
- 2007-05-17 US US11/804,137 patent/US7668598B2/en active Active
- 2007-05-17 EP EP07794979.0A patent/EP2024006B1/de active Active
- 2007-05-17 WO PCT/US2007/011820 patent/WO2007136694A2/en active Application Filing
-
2010
- 2010-01-11 US US12/685,557 patent/US8046082B2/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004034885A2 (en) * | 2002-10-15 | 2004-04-29 | Medtronic Inc. | Signal quality monitoring and control for a medical device system |
Also Published As
Publication number | Publication date |
---|---|
US8046082B2 (en) | 2011-10-25 |
US20080033510A1 (en) | 2008-02-07 |
WO2007136694A2 (en) | 2007-11-29 |
US7668598B2 (en) | 2010-02-23 |
US20100114259A1 (en) | 2010-05-06 |
WO2007136694A3 (en) | 2008-10-23 |
EP2024006A4 (de) | 2009-05-27 |
DK2024006T3 (en) | 2019-02-04 |
EP2024006A2 (de) | 2009-02-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2024006B1 (de) | Vorrichtung zur nervenstimulation bei einem patienten | |
US9265941B2 (en) | Lead set for nerve stimulator and method of operation thereof | |
US11576599B2 (en) | Stimulation device adapter | |
EP1993440A2 (de) | Systeme und verfahren zur unterscheidung und/oder identifikation von durch darauf ausgerichtete nerven angeregten gewebebereichen zu diagnose- und/oder behandlungszwecken | |
US20220233849A1 (en) | Systems and methods for delivering neuroregenerative therapy | |
US11247044B2 (en) | Devices for delivering neuroregenerative therapy | |
CA2924050C (en) | Stimulation device adapter | |
AU2017254920B2 (en) | Method of reducing renal hypertension and computer-readable medium | |
EP2024017A2 (de) | Elektrodenset für nervenstimulator und bedienungsverfahren dafür | |
US11623091B2 (en) | Portable electrical stimulation system and method | |
AU2019204642B2 (en) | Method for reducing overactive bladder syndrome and computer-readable medium thereof | |
Walsh | Introduction to low frequency currents |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20081212 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20090429 |
|
DAX | Request for extension of the european patent (deleted) | ||
17Q | First examination report despatched |
Effective date: 20141013 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Ref document number: 602007056460 Country of ref document: DE Free format text: PREVIOUS MAIN CLASS: A61N0001040000 Ipc: A61N0001360000 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61N 1/36 20060101AFI20180126BHEP Ipc: A61N 1/375 20060101ALI20180126BHEP |
|
INTG | Intention to grant announced |
Effective date: 20180301 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAJ | Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deleted |
Free format text: ORIGINAL CODE: EPIDOSDIGR1 |
|
GRAL | Information related to payment of fee for publishing/printing deleted |
Free format text: ORIGINAL CODE: EPIDOSDIGR3 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
INTC | Intention to grant announced (deleted) | ||
GRAR | Information related to intention to grant a patent recorded |
Free format text: ORIGINAL CODE: EPIDOSNIGR71 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
GRAJ | Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deleted |
Free format text: ORIGINAL CODE: EPIDOSDIGR1 |
|
GRAR | Information related to intention to grant a patent recorded |
Free format text: ORIGINAL CODE: EPIDOSNIGR71 |
|
GRAJ | Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deleted |
Free format text: ORIGINAL CODE: EPIDOSDIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
GRAR | Information related to intention to grant a patent recorded |
Free format text: ORIGINAL CODE: EPIDOSNIGR71 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE PATENT HAS BEEN GRANTED |
|
INTG | Intention to grant announced |
Effective date: 20180809 |
|
INTC | Intention to grant announced (deleted) | ||
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
INTG | Intention to grant announced |
Effective date: 20180903 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP Ref country code: AT Ref legal event code: REF Ref document number: 1050539 Country of ref document: AT Kind code of ref document: T Effective date: 20181015 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D Ref country code: DE Ref legal event code: R096 Ref document number: 602007056460 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: FP |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: NV Representative=s name: ING. MARCO ZARDI C/O M. ZARDI AND CO. S.A., CH |
|
REG | Reference to a national code |
Ref country code: DK Ref legal event code: T3 Effective date: 20190128 |
|
REG | Reference to a national code |
Ref country code: SE Ref legal event code: TRGR |
|
REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG4D |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190210 Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190110 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 Ref country code: PL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 Ref country code: LV Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190111 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190210 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 20190315 Year of fee payment: 13 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: LU Payment date: 20190510 Year of fee payment: 13 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602007056460 Country of ref document: DE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DK Payment date: 20190510 Year of fee payment: 13 Ref country code: IT Payment date: 20190527 Year of fee payment: 13 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: NO Payment date: 20190425 Year of fee payment: 11 |
|
26N | No opposition filed |
Effective date: 20190711 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: AT Payment date: 20190425 Year of fee payment: 13 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190517 |
|
REG | Reference to a national code |
Ref country code: DK Ref legal event code: EBP Effective date: 20200531 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MM01 Ref document number: 1050539 Country of ref document: AT Kind code of ref document: T Effective date: 20200517 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20200517 Ref country code: SE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20200518 |
|
REG | Reference to a national code |
Ref country code: BE Ref legal event code: MM Effective date: 20200531 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20200517 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DK Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20200531 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20200531 Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20070517 Ref country code: MT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20181010 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20200517 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: UEP Ref document number: 1050539 Country of ref document: AT Kind code of ref document: T Effective date: 20181010 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: NL Payment date: 20230526 Year of fee payment: 17 Ref country code: FR Payment date: 20230525 Year of fee payment: 17 Ref country code: DE Payment date: 20230530 Year of fee payment: 17 Ref country code: CH Payment date: 20230610 Year of fee payment: 17 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20230529 Year of fee payment: 17 |